Role of individual genes of the A/Leningrad/134/17/57 (H2N2) cold-adapted donor strain in manifestation of the temperature-sensitive phenotype of reassortant influenza A viruses

International Congress Series

Volumn 1263, Issue C, 2004, Pages 547-550

  Kiseleva, I ^a,b   Klimov, A ^c   Su, Q ^a   Szymkowiak, C ^a   Toner, T J ^a   Kwan, W S ^a   Rudenko, L ^b   Shaw, A R ^a   Youil, R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Russian Federation)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Cold adapted; Influenza; Phenotype

Indexed keywords

EID: 84961387593     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/j.ics.2004.02.156     Document Type: Article

References (4)

1. Klimov, A.I., Cox, N.J., PCR restriction analysis of genome composition and stability of cold-adapted reassortant live influenza vaccines. J. Virol. Methods 52 (1995), 41–49.
2. Klimov, A.I., et al. Sequence changes in the live attenuated, cold-adapted variants of influenza A/Leningrad/134/57 (H2N2) virus. Virology 86 (1992), 795–797.
3. Klimov, A.I., et al. Genes coding for polymerase proteins are essential for attenuation of the cold-adapted A/Leningrad/134/17/57 (H2N2) influenza virus. Osterhaus, A.D.M.E, Cox, N, Hampson, A.W., (eds.) Options for the Control of Influenza IV International Congress Series, vol. 1219, 2001, Elsevier, Amsterdam, 955–959.
4. Kiseleva, I, et al. Cell based assay for the determination of temperature sensitive and cold adapted phenotype of influenza viruses. J. Virol. Methods 116 (2004), 71–78.