Methylation of viral and host genes and severity of cervical lesions associated with human papillomavirus type 16

International Journal of Cancer

Volumn 136, Issue 6, 2015, Pages E638-E645

  Louvanto, Karolina ^a   Franco, Eduardo L ^a   Ramanakumar, Agnihotram V ^a   Vasiljević, Nataša ^b   Scibior Bentkowska, Dorota ^b   Koushik, Anita ^c   Cuzick, Jack ^b   Coutlée, Francois ^c   Lorincz, Attila T ^b   Pollak, M ^d   Roger, M ^d   Duarte, E ^d   Slavtcheva, N ^d   Piche S ^d   Rahimi, K ^d   Ferenczy, A ^d   Arseneau, J ^d   Voyer, H ^d   Forest, P ^d   Provencher, D ^d   Gilbert, L ^d   Capek, A ^d   Juras, A ^d   Michon, B ^d   Florakas, C ^d   Landry, D ^d   Grandmont, D ^d   L'Heureux, D ^d   Dalton, D ^d   Queiros, E ^d   Dauth, E ^d   Leclerc, F ^d   Stanimir, G ^d   Hum, H S ^d   Czitrom, J P ^d   Dubuc Lissoir, J ^d   Lord, J ^d   Mayrand, M H ^d   Dupuis, M J ^d   Martin, M ^d   Roleau, M ^d   Plamondon, M ^d   Mansour, N ^d   Fournier, P ^d,d   Gauthier, P ^d   Drouin, P ^d   Jeanbart, P ^d   Shatz, R ^d   Piche R ^d   Hunt, R ^d   more..

^a MCGILL UNIVERSITY   (Canada)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^c CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

^d NONE

Author keywords

Biomarker; Cervical intraepithelial neoplasia (CIN); DNA methylation; HPV16; Human papillomavirus (HPV)

Indexed keywords

DNA;

ADULT; ARTICLE; CANCER RISK; CONTROLLED STUDY; CPG ISLAND; DISEASE SEVERITY; DNA METHYLATION; EPB41L3 GENE; FEMALE; GENE; HUMAN; HUMAN CELL; HUMAN PAPILLOMAVIRUS TYPE 16; LMX1 GENE; MAJOR CLINICAL STUDY; PAPILLOMAVIRUS INFECTION; PREDICTION; RECEIVER OPERATING CHARACTERISTIC; TUMOR DIFFERENTIATION; UTERINE CERVIX CANCER; UTERINE CERVIX CARCINOMA; UTERINE CERVIX CARCINOMA IN SITU; GENETICS; SEVERITY OF ILLNESS INDEX; UTERINE CERVIX TUMOR; VIROLOGY;

ADULT; CERVICAL INTRAEPITHELIAL NEOPLASIA; DNA METHYLATION; FEMALE; HUMAN PAPILLOMAVIRUS 16; HUMANS; ROC CURVE; SEVERITY OF ILLNESS INDEX; UTERINE CERVICAL NEOPLASMS;

EID: 84961291208     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29196     Document Type: Article

References (33)

1. Walboomers J.M., Jacobs M.V., Manos M.M., et al. Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol 1999; 189: 12-9.
2. Ferlay J. , Shin H.R., Bray F., et al. Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer 2010; 127: 2893-2917.
3. Schiffman M, Castle PE, Jeronimo J, et al. Human papillomavirus and cervical cancer. Lancet 2007;370:890-907.
4. Louvanto K, Chevarie-Davis M, Ramanakumar AV, et al. HPV testing with cytology triage for cervical cancer screening in routine practice. Am J Obstet Gynecol 2014;210:474.e1-7.
5. Leeson SC, Alibegashvili T, Arbyn M, et al. HPV testing and vaccination in Europe. J Low Genit Tract Dis 2014;18:61-9.
6. Cuzick J, Bergeron C, von Knebel Doeberitz M, et al. New technologies and procedures for cervical cancer screening. Vaccine 2012;30 (Suppl 5):F107-16.
7. Wentzensen N, Sherman ME, Schiffman M, et al. Utility of methylation markers in cervical cancer early detection: appraisal of the state-of-the-science. Gynecol Oncol 2009;112:293-9.
8. Clarke MA, Wentzensen N, Mirabello L, et al. Human papillomavirus DNA methylation as a potential biomarker for cervical cancer. Cancer Epidemiol Biomarkers Prev 2012;21:2125-37.
9. Kalantari M, Osann K, Calleja-Macias IE, et al. Methylation of human papillomavirus 16, 18, 31, and 45 L2 and L1 genes and the cellular DAPK gene: considerations for use as biomarkers of the progression of cervical neoplasia. Virology 2014;448:314-21.
10. Hesselink AT, Berkhof J, Heideman DA, et al. High-risk human papillomavirus DNA load in a population-based cervical screening cohort in relation to the detection of high-grade cervical intraepithelial neoplasia and cervical cancer. Int J Cancer 2009;124:381-6.
11. Hesselink AT, Heideman DA, Steenbergen RD, et al. Combined promoter methylation analysis of CADM1 and MAL: an objective triage tool for high-risk human papillomavirus DNA-positive women. Clin Cancer Res 2011;17:2459-65.
12. Hesselink AT, Heideman DA, Steenbergen RD, et al. Methylation marker analysis of self-sampled cervico-vaginal lavage specimens to triage high-risk HPV-positive women for colposcopy. Int J Cancer 2014;135:880-6.
13. Verhoef VM, Bosgraaf RP, van Kemenade FJ, et al. Triage by methylation-marker testing versus cytology in women who test HPV-positive on self-collected cervicovaginal specimens (PROH-TECT-3): a randomised controlled non-inferiority trial. Lancet Oncol 2014;15:315-22.
14. Li N, Franceschi S, Howell-Jones R, et al. Human papillomavirus type distribution in 30,848 invasive cervical cancers worldwide: variation by geographical region, histological type and year of publication. Int J Cancer 2011;128:927-35.
15. Malogajski J, Brankovic I, Verweij SP, et al. Translational potential into health care of basic genomic and genetic findings for human immunodeficiency virus, Chlamydia trachomatis, and human papilloma virus. Biomed Res Int 2013;2013:892106.
16. Lorincz AT, Brentnall AR, Vasiljevic N, et al. HPV16 L1 and L2 DNA methylation predicts high-grade cervical intraepithelial neoplasia in women with mildly abnormal cervical cytology. Int J Cancer 2013;133:637-44.
17. Wang SS, Smiraglia DJ, Wu YZ, et al. Identification of novel methylation markers in cervical cancer using restriction landmark genomic scanning. Cancer Res 2008;68:2489-97.
18. Mirabello L, Schiffman M, Ghosh A, et al. Elevated methylation of HPV16 DNA is associated with the development of high grade cervical intraepithelial neoplasia. Int J Cancer 2013;132:1412-22.
19. Lai HC, Lin YW, Huang TH, et al. Identification of novel DNA methylation markers in cervical cancer. Int J Cancer 2008;123:161-7.
20. Eijsink JJ, Lendvai A, Deregowski V, et al. A four-gene methylation marker panel as triage test in high-risk human papillomavirus positive patients. Int J Cancer 2012;130:1861-9.
21. Vasiljevic N, Scibior-Bentkowska D, Brentnall AR, et al. Credentialing of DNA methylation assays for human genes as diagnostic biomarkers of cervical intraepithelial neoplasia in high-risk HPV positive women. Gynecol Oncol 2014;132:709-14.
22. Koushik A, Ghosh A, Duarte-Franco E, et al. The p53 codon 72 polymorphism and risk of high-grade cervical intraepithelial neoplasia. Cancer Detect Prev 2005;29:307-16.
23. Mayrand MH, Duarte-Franco E, Coutlee F, et al. Randomized controlled trial of human papilloma-virus testing versus Pap cytology in the primary screening for cervical cancer precursors: design, methods and preliminary accrual results of the Canadian cervical cancer screening trial (CCCaST). Int J Cancer 2006;119:615-23.
24. Bernkopf DB, Williams ED. Potential role of EPB41L3 (protein 4.1B/Dal-1) as a target for treatment of advanced prostate cancer. Expert Opin Ther Targets 2008;12:845-53.
25. Heller G, Geradts J, Ziegler B, et al. Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer. Breast Cancer Res Treat 2007;103:283-91.
26. Chizhikov VV, Millen KJ. Control of roof plate formation by Lmx1a in the developing spinal cord. Development 2004;131:2693-705.
27. Brentnall AR, Vasiljevic N, Scibior-Bentkowska D, et al. A DNA methylation classifier of cervical precancer based on human papillomavirus and human genes. Int J Cancer 2014;135:1425-32.
28. Franco EL. Statistical issues in human papilloma-virus testing and screening. Clin Lab Med 2000;20:345-67.
29. Carreon JD, Sherman ME, Guillen D, et al. CIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of population-based cervical samples. Int J Gynecol Pathol 2007;26:441-6.
30. Tang D, Kryvenko ON, Mitrache N, et al. Methylation of the RARB gene increases prostate cancer risk in black Americans. J Urol 2013;190:317-24.
31. Laberge AM, Michaud J, Richter A, et al. Population history and its impact on medical genetics in Quebec. Clin Genet 2005;68:287-301.
32. Senchenko VN, Kisseljova NP, Ivanova TA, et al. Novel tumor suppressor candidates on chromosome 3 revealed by NotI-microarrays in cervical cancer. Epigenetics 2013;8:409-20
33. Wentzensen N, Sun C, Ghosh A, et al. Methylation of HPV18, HPV31, and HPV45 genomes and cervical intraepithelial neoplasia grade 3. J Natl Cancer Inst 2012;104:1738-49.