Vernalizing cold is registered digitally at FLC

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 13, 2015, Pages 4146-4151

  Angel, Andrew ^a,b,c   Song, Jie ^b,d   Yang, Hongchun ^b   Questa, Julia I ^b   Dean, Caroline ^b   Howard, Martin ^a,b  

^a Computational and Systems Biology ^*  (United Kingdom)

^b JOHN INNES CENTRE   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Analog; Digital; FLC; Temperature; Vernalization

Indexed keywords

MESSENGER RNA; ARABIDOPSIS PROTEIN; FLF PROTEIN, ARABIDOPSIS; MADS DOMAIN PROTEIN;

ARABIDOPSIS THALIANA; ARTICLE; CELL POPULATION; COLD; COLD EXPOSURE; COLD TREATMENT; CONTROLLED STUDY; DNA REPLICATION; EPIGENETICS; FLOWERING; FLOWERING LOCUS C; GENE EXPRESSION; HISTONE MODIFICATION; MATHEMATICAL MODEL; NONHUMAN; PLANT GROWTH; PRIORITY JOURNAL; PROTEIN EXPRESSION; REPRESSOR GENE; SIGNAL TRANSDUCTION; VERNALIZATION; ARABIDOPSIS; CHROMATIN IMMUNOPRECIPITATION; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC PROCEDURES; GENETICS; METABOLISM; PROBABILITY; REAL TIME POLYMERASE CHAIN REACTION; STATISTICS; THEORETICAL MODEL;

ARABIDOPSIS THALIANA;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CHROMATIN IMMUNOPRECIPITATION; COLD TEMPERATURE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, PLANT; GENETIC TECHNIQUES; MADS DOMAIN PROTEINS; MODELS, THEORETICAL; PROBABILITY; REAL-TIME POLYMERASE CHAIN REACTION; STOCHASTIC PROCESSES;

EID: 84961289745     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1503100112     Document Type: Article

References (23)

1. López-Maury L, Marguerat S, Bähler J (2008) Tuning gene expression to changing environments: From rapid responses to evolutionary adaptation. Nat Rev Genet 9(8): 583-593.
2. de Nadal E, Ammerer G, Posas F (2011) Controlling gene expression in response to stress. Nat Rev Genet 12(12):833-845.
3. Franklin KA, Toledo-Ortiz G, Pyott DE, Halliday KJ (2014) Interaction of light and temperature signalling. J Exp Bot 65(11):2859-2871.
4. Kaufman PD, Rando OJ (2010) Chromatin as a potential carrier of heritable information. Curr Opin Cell Biol 22(3):284-290.
5. Margueron R, Reinberg D (2010) Chromatin structure and the inheritance of epigenetic information. Nat Rev Genet 11(4):285-296.
6. Steffen PA, Ringrose L (2014) What are memories made of? How Polycomb and Trithorax proteins mediate epigenetic memory. Nat Rev Mol Cell Biol 15(5):340-356.
7. Steffen PA, Fonseca JP, Ringrose L (2012) Epigenetics meets mathematics: Towards a quantitative understanding of chromatin biology. BioEssays 34(10):901-913.
8. Casadesüs J, Low DA (2013) Programmed heterogeneity: Epigenetic mechanisms in bacteria. J Biol Chem 288(20):13929-13935.
9. Amasino R (2010) Seasonal and developmental timing of flowering. Plant J 61(6): 1001-1013.
10. Song J, Angel A, Howard M, Dean C (2012) Vernalization-a cold-induced epigenetic switch. J Cell Sci 125(Pt 16):3723-3731.
11. Finnegan EJ, Dennis ES (2007) Vernalization-induced trimethylation of histone H3 lysine 27 at FLC is not maintained in mitotically quiescent cells. Curr Biol 17(22): 1978-1983.
12. Angel A, Song J, Dean C, Howard M (2011) A Polycomb-based switch underlying quantitative epigenetic memory. Nature 476(7358):105-108.
13. Satake A, Iwasa Y (2012) A stochastic model of chromatin modification: Cell population coding of winter memory in plants. J Theor Biol 302(0):6-17.
14. Rosa S, et al. (2013) Physical clustering of FLC alleles during Polycomb-mediated epigenetic silencing in vernalization. Genes Dev 27(17):1845-1850.
15. Yang H, Howard M, Dean C (2014) Antagonistic roles for H3K36me3 and H3K27me3 in the cold-induced epigenetic switch at Arabidopsis FLC. Curr Biol 24(15):1793-1797.
16. Dodd IB, Micheelsen MA, Sneppen K, Thon G (2007) Theoretical analysis of epigenetic cell memory by nucleosome modification. Cell 129(4):813-822.
17. Heard E, Martienssen RA (2014) Transgenerational epigenetic inheritance: Myths and mechanisms. Cell 157(1):95-109.
18. Conaway JW (2012) Introduction to theme "Chromatin, epigenetics, and transcription". Annu Rev Biochem 81:61-64.
19. Storz G (1999) An RNA thermometer. Genes Dev 13(6):633-636.
20. Narberhaus F, Waldminghaus T, Chowdhury S (2006) RNA thermometers. FEMS Microbiol Rev 30(1):3-16.
21. Sung S, Amasino RM (2004) Vernalization in Arabidopsis thaliana is mediated by the PHD finger protein VIN3. Nature 427(6970):159-164.
22. Aikawa S, Kobayashi MJ, Satake A, Shimizu KK, Kudoh H (2010) Robust control of the seasonal expression of the Arabidopsis FLC gene in a fluctuating environment. Proc Natl Acad Sci USA 107(25):11632-11637.
23. Lee I, et al. (1994) The late-flowering phenotype of FRIGIDA and mutations in LUMINIDEPENDENS is suppressed in the Landsberg erecta strain of Arabidopsis. Plant J 6(6):903-909.