Human Induced Pluripotent Stem Cells for Tumor Targeted Delivery of Gold Nanorods and Enhanced Photothermal Therapy

ACS Nano

Volumn 10, Issue 2, 2016, Pages 2375-2385

  Liu, Yanlei ^a,b   Yang, Meng ^a,b   Zhang, Jingpu ^b   Zhi, Xiao ^b   Li, Chao ^b   Zhang, Chunlei ^a   Pan, Fei ^a,c   Wang, Kan ^a   Yang, Yuming ^a   Martinez De La Fuentea, Jesus ^d   Cui, Daxiang ^a,c  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b School of Biomedical Engineering   (China)

^c SHANGHAI JIAO TONG UNIVERSITY   (China)

^d UNIVERSITY OF ZARAGOZA   (Spain)

Author keywords

Au nanorods; CXCR4; induced pluripotent stem cells; photothermal therapy

Indexed keywords

CELLS; CYTOLOGY; MAMMALS; NANOPARTICLES; NANORODS; OPTICAL PROPERTIES; PHOTOACOUSTIC EFFECT; PLASMONS; STEM CELLS; TUMORS;

AU NANO RODS; CXCR4; HUMAN-INDUCED PLURIPOTENT STEM CELLS; INDUCED PLURIPOTENT STEM CELLS; PHOTOACOUSTIC TOMOGRAPHY; PHOTOTHERMAL THERAPY; TUMOR TARGETED DELIVERY; TWO-PHOTON LUMINESCENCE;

GOLD;

CHEMOKINE RECEPTOR CXCR4; CXCR4 PROTEIN, HUMAN; GOLD; NANOTUBE; SILICON DIOXIDE;

ANIMAL; BAGG ALBINO MOUSE; CELL LINE; CHEMISTRY; FEMALE; HUMAN; INDUCED PLURIPOTENT STEM CELL; MOUSE; NUDE MOUSE; PHOTOCHEMOTHERAPY; PROCEDURES; TRANSPLANTATION; TUMOR CELL LINE;

ANIMALS; CELL LINE; CELL LINE, TUMOR; FEMALE; GOLD; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; NANOTUBES; PHOTOCHEMOTHERAPY; RECEPTORS, CXCR4; SILICON DIOXIDE;

EID: 84961231096     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/acsnano.5b07172     Document Type: Article

References (36)

1. Wang, D.; Xu, Z.; Yu, H.; Chen, X.; Feng, B.; Cui, Z.; Lin, B.; Yin, Q.; Zhang, Z.; Chen, C.; Wang, J.; Zhang, W.; Li, Y. Treatment of Metastatic Breast Cancer by Combination of Chemotherapy and Photothermal Ablation Using Doxorubicin-Loaded DNA Wrapped Gold Nanorods Biomaterials 2014, 35, 8374-8384 10.1016/j.biomaterials.2014.05.094
2. Zhang, Z.; Wang, J.; Nie, X.; Wen, T.; Ji, Y.; Wu, X.; Zhao, Y.; Chen, C. Near Infrared Laser-Induced Targeted Cancer Therapy Using Thermoresponsive Polymer Encapsulated Gold Nanorods J. Am. Chem. Soc. 2014, 136, 7317-7326 10.1021/ja412735p
3. Nima, Z. A.; Mahmood, M.; Xu, Y.; Mustafa, T.; Watanabe, F.; Nedosekin, D. A.; Juratli, M. A.; Fahmi, T.; Galanzha, E. I.; Nolan, J. P.; Basnakian, A. G.; Zharov, V. P.; Biris, A. S. Circulating Tumor Cell Identification by Functionalized Silver-Gold Nanorods with Multicolor, Super-Enhanced SERS and Photothermal Resonances Sci. Rep. 2014, 4, 4752 10.1038/srep04752
4. Wang, H.; Huff, T. B.; Zweifel, D. A.; He, W.; Low, P. S.; Wei, A.; Cheng, J. X. In Vitro and In Vivo Two-Photon Luminescence Imaging of Single Gold Nanorods Proc. Natl. Acad. Sci. U. S. A. 2005, 102, 15752-15756 10.1073/pnas.0504892102
5. Huff, T. B.; Hansen, M. N.; Zhao, Y.; Cheng, J. X.; Wei, A. Controlling The Cellular Uptake of Gold Nanorods Langmuir 2007, 23, 1596-1599 10.1021/la062642r
6. Khaing, O. M. K.; Yang, Y.; Hu, Y.; Gomez, M.; Du, H.; Wang, H. Gold Nanoparticle-Enhanced and Size-Dependent Generation of Reactive Oxygen Species from Protoporphyrin IX ACS Nano 2012, 6, 1939-1947 10.1021/nn300327c
7. Choi, J.; Yang, J.; Bang, D.; Park, J.; Suh, J. S.; Huh, Y. M.; Haam, S. Targetable Gold Nanorods for Epithelial Cancer Therapy Guided by Near-IR Absorption Imaging Small 2012, 8, 746-753 10.1002/smll.201101789
8. He, R.; Wang, Y. C.; Wang, X.; Wang, Z.; Liu, G.; Zhou, W.; Wen, L.; Li, Q.; Wang, X.; Chen, X.; Zeng, J.; Hou, J. G. Facile Synthesis of Pentacle Gold-Copper Alloy Nanocrystals and Their Plasmonic and Catalytic Properties Nat. Commun. 2014, 5, 4327 10.1038/ncomms5327
9. Aboody, K. S.; Najbauer, J.; Metz, M. Z.; D'Apuzzo, M.; Gutova, M.; Annala, A. J.; Synold, T. W.; Couture, L. A.; Blanchard, S.; Moats, R. A. Neural Stem Cell-Mediated Enzyme/Prodrug Therapy for Glioma: Preclinical Studies Sci. Transl. Med. 2013, 5, 184ra59 10.1126/scitranslmed.3005365
10. Cho, S. K.; Emoto, K.; Su, L. J.; Yang, X.; Flaig, T. W.; Park, W. Functionalized Gold Nanorods for Thermal Ablation Treatment of Bladder Cancer J. Biomed. Nanotechnol. 2014, 10, 1267-1276 10.1166/jbn.2014.1838
11. Xiao, Y.; Hong, H.; Matson, V. Z.; Javadi, A.; Xu, W.; Yang, Y.; Zhang, Y.; Engle, J. W.; Nickles, R. J.; Cai, W.; Steeber, D. A.; Gong, S. Gold Nanorods Conjugated with Doxorubicin and CRGD for Combined Anticancer Drug Delivery and PET Imaging Theranostics 2012, 2, 757-768 10.7150/thno.4756
12. Stuckey, D. W.; Shah, K. Stem Cell-Based Therapies for Cancer Treatment: Separating Hope from Hype Nat. Rev. Cancer 2014, 14, 683-691 10.1038/nrc3798
13. Stoff-Khalili, M. A.; Rivera, A. A.; Mathis, J. M.; Banerjee, N. S.; Moon, A. S.; Hess, A.; Rocconi, R. P.; Numnum, T. M.; Everts, M.; Chow, L. T.; Douqlas, J. T.; Sieqal, G. P.; Zhu, Z. B.; Bender, H. G.; Dall, P.; Stoff, A.; Pereboeva, L.; Curiel, D. T. Mesenchymal Stem Cells as A Vehicle for Targeted Delivery of CRAds to Lung Metastases of Breast Carcinoma Breast Cancer Res. Treat. 2007, 105, 157-167 10.1007/s10549-006-9449-8
14. Takahashi, K.; Yamanaka, S. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors Cell 2006, 126, 663-676 10.1016/j.cell.2006.07.024
15. Robinton, D. A.; Daley, G. Q. The Promise of Induced Pluripotent Stem Cells in Research and Therapy Nature 2012, 481, 295-305 10.1038/nature10761
16. Zlotnik, A.; Yoshie, O. Chemokines: A New Classification System and Their Role in Immunity Immunity 2000, 12, 121-127 10.1016/S1074-7613(00)80165-X
17. Kucia, M.; Jankowski, K.; Reca, R.; Wysoczynski, M.; Bandura, L.; Allendorf, D. J.; Zhang, J.; Ratajczak, J.; Ratajczak, M. Z. CXCR4-SDF-1 Signalling, Locomotion, Chemotaxis and Adhesion J. Mol. Histol. 2004, 35, 233-245 10.1023/B:HIJO.0000032355.66152.b8
18. Koizumi, S.; Gu, C.; Amano, S.; Yamamoto, S.; Ihara, H.; Tokuyama, T.; Namba, H. Migration of Mouse-Induced Pluripotent Stem Cells to Glioma-Conditioned Medium Is Mediated by Tumor-Associated Specific Growth Factors Oncol. Lett. 2011, 2, 283-288 10.3892/ol.2011.234
19. Zong, S.; Wang, Z.; Yang, J.; Wang, C.; Xu, S.; Cui, Y. A SERS and Fluorescence Dual Mode Cancer Cell Targeting Probe Based on Silica Coated Au@Ag Core-Shell Nanorods Talanta 2012, 97, 368-75 10.1016/j.talanta.2012.04.047
20. Huang, P.; Bao, L.; Zhang, C.; Lin, J.; Luo, T.; Yang, D.; He, M.; Li, Z.; Gao, G.; Gao, B.; Fu, S.; Cui, D. Folic Acid-Conjugated Silica-Modified Gold Nanorods for X-ray/CT Imaging-Guided Dual-Mode Radiation and Photo-Thermal Therapy Biomaterials 2011, 32, 9796-9809 10.1016/j.biomaterials.2011.08.086
21. Wang, L.; Liu, Y.; Li, W.; Jiang, X.; Ji, Y.; Wu, X.; Xu, L.; Qiu, Y.; Zhao, K.; Wei, T.; Li, Y.; Zhao, Y.; Chen, C. Selective Targeting of Gold Nanorods at The Mitochondria of Cancer Cells: Implications for Cancer Therapy Nano Lett. 2011, 11, 772-780 10.1021/nl103992v
22. Madsen, S. J.; Baek, S. K.; Makkouk, A. R.; Krasieva, T.; Hirschberg, H. Macrophages as Cell-Based Delivery Systems for Nanoshells In Photothermal Therapy Ann. Biomed. Eng. 2012, 40, 507-515 10.1007/s10439-011-0415-1
23. Stephan, M. T.; Stephan, S. B.; Bak, P.; Chen, J.; Irvine, D. J. Synapse-Directed Delivery of Immunomodulators Using T-Cell-Conjugated Nanoparticles Biomaterials 2012, 33, 5776-5787 10.1016/j.biomaterials.2012.04.029
24. Klopp, A. H.; Gupta, A.; Spaeth, E.; Andreeff, M.; Marini, F. Concise Review: Dissecting ADiscrepancy in The Literature: Do Mesenchymal Stem Cells Support or Suppress Tumor Growth? Stem Cells 2011, 29, 11-19 10.1002/stem.559
25. Zhang, W.; Ji, Y.; Wu, X.; Xu, H. Trafficking of Gold Nanorods in Breast Cancer Cells: Uptake, Lysosome Maturation, and Elimination ACS Appl. Mater. Interfaces 2013, 5, 9856-9865 10.1021/am4033857
26. Mooney, R.; Roma, L.; Zhao, D.; Van Haute, D.; Garcia, E.; Kim, S. U.; Annala, A. J.; Aboody, K. S.; Berlin, J. M. Neural Stem Cell-Mediated Intratumoral Delivery of Gold Nanorods Improves Photothermal Therapy ACS Nano 2014, 8, 12450-12460 10.1021/nn505147w
27. Liang, S.; Li, C.; Zhang, C.; Chen, Y.; Xu, L.; Bao, C.; Wang, X.; Liu, G.; Zhang, F.; Cui, D. CD44v6Monoclonal Antibody-Conjugated Gold Nanostars for Targeted Photoacoustic Imaging and Plasmonic Photothermal Therapy of Gastric Cancer Stem-like Cells Theranostics 2015, 5, 970-984 10.7150/thno.11632
28. Song, C. W.; Park, H. J.; Lee, C. K.; Griffin, R. Implications of Increased Tumor Blood Flow and Oxygenation Caused by Mild Temperature Hyperthermia in Tumor Treatment Int. J. Hyperthermia 2005, 21, 761-767 10.1080/02656730500204487
29. Zheng, M.; Yue, C.; Ma, Y.; Gong, P.; Zhao, P.; Zheng, C.; Sheng, Z.; Zhang, P.; Wang, Z.; Cai, L. Single-Step Assembly of DOX/ICG Loaded Lipid-Polymer Nanoparticles for Highly Effective Chemo-Photothermal Combination Therapy ACS Nano 2013, 7, 2056-2067 10.1021/nn400334y
30. Chithrani, B. D.; Ghazani, A. A.; Chan, W. C. Determining The Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells Nano Lett. 2006, 6, 662-668 10.1021/nl052396o
31. Turk, B.; Stoka, V. Protease Signalling in Cell Death: Caspases Versus Cysteine Cathepsins FEBS Lett. 2007, 581, 2761-2767 10.1016/j.febslet.2007.05.038
32. Perez-Hernandez, M.; Del Pino, P.; Mitchell, S. G.; Moros, M.; Stepien, G.; Pelaz, B.; Parak, W. J.; Galvez, E. M.; Pardo, J.; de la Fuente, J. M. Dissecting The Molecular Mechanism of Apoptosis During Photothermal Therapy Using Gold Nanoprisms ACS Nano 2015, 9, 52-61 10.1021/nn505468v
33. Gorelikov, I.; Matsuura, N. Single-Step Coating of Mesoporous Silica on Cetyltrimethyl Ammonium Bromide-Capped Nanoparticles Nano Lett. 2008, 8, 369-373 10.1021/nl0727415
34. Zhang, Z.; Wang, L.; Wang, J.; Jiang, X.; Li, X.; Hu, Z.; Ji, Y.; Wu, X.; Chen, C. Mesoporous Silica-Coated Gold Nanorods as A Light-Mediated Multifunctional Theranostic Platform for Cancer Treatment Adv. Mater. 2012, 24, 1418-1423 10.1002/adma.201104714
35. Durr, N. J.; Larson, T.; Smith, D. K.; Korgel, B. A.; Sokolov, K.; Ben-Yakar, A. Two-Photon Luminescence Imaging of Cancer Cells Using Molecularly Targeted Gold Nanorods Nano Lett. 2007, 7, 941-945 10.1021/nl062962v
36. Xu, Y.; Wang, J.; Li, X.; Liu, Y.; Dai, L.; Wu, X.; Chen, C. Selective Inhibition of Breast Cancer Stem Cells by Gold Nanorods Mediated Plasmonic Hyperthermia Biomaterials 2014, 35, 4667-4677 10.1016/j.biomaterials.2014.02.035