Bacteriological spectrum and antimicrobial susceptibility pattern of neonatal septicaemia in a tertiary care hospital of North India

Journal of Maternal-Fetal and Neonatal Medicine

Volumn 29, Issue 24, 2016, Pages 3993-3998

  Lamba, Mamta ^a   Sharma, Rajni ^a   Sharma, Deepak ^b   Choudhary, Mukesh ^c   Maheshwari, Rakesh Kumar ^a  

^a SMS MEDICAL COLLEGE   (India)

^b POST GRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^c GCRI   (India)

Author keywords

Antimicrobial susceptibility; blood culture; changing bacterial spectrum; neonatal septicaemia

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; AMPICILLIN; CEFOTAXIME; CEFOXITIN; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; GENTAMICIN; IMIPENEM; LINEZOLID; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TEICOPLANIN; VANCOMYCIN;

ACINETOBACTER; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; BLOOD CULTURE; BLOOD SAMPLING; BURKHOLDERIA; CITROBACTER; COAGULASE NEGATIVE STAPHYLOCOCCUS; DISK DIFFUSION; ENTEROBACTER AEROGENES; ENTEROBACTER CLOACAE; ENTEROCOCCUS; ESCHERICHIA COLI; FEMALE; GRAM NEGATIVE SEPSIS; GRAM POSITIVE BACTERIUM; HAFNIA; HUMAN; INDIA; INFECTION RISK; KLEBSIELLA; MAJOR CLINICAL STUDY; MALE; NEWBORN; NEWBORN SEPSIS; NONHUMAN; OBSERVATIONAL STUDY; ONSET AGE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PSEUDOMONAS; TERTIARY CARE CENTER; ANTIBIOTIC RESISTANCE; BACTEREMIA; GRAM NEGATIVE INFECTION; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; NEONATAL INTENSIVE CARE UNIT; STAPHYLOCOCCUS;

BACTEREMIA; DRUG RESISTANCE, BACTERIAL; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; INDIA; INFANT, NEWBORN; INTENSIVE CARE UNITS, NEONATAL; KLEBSIELLA; MALE; MICROBIAL SENSITIVITY TESTS; NEONATAL SEPSIS; PROSPECTIVE STUDIES; STAPHYLOCOCCUS; TERTIARY CARE CENTERS;

EID: 84961217206     PISSN: 14767058     EISSN: 14764954     Source Type: Journal    
DOI: 10.3109/14767058.2016.1152251     Document Type: Article

References (36)

1. Freij BJ, George H, McCraken JR., Acute infections. In:Neonatology-pathophysiology and management of the new born. 4th edn. Philadelphia:JP Lippincott Company; 2005:1082–116
2. Singh M., Care of the newborn; 6th edn.; Meharban Singh, Sagar Publications; New Delhi; 2004:212–20
3. Report of the National Neonatal Perinatal Database (National Neonatology Forum) 2005:2002–03
4. Nimboor K, Ravindranath. Bacteriological (aerobic) study of neonatal septicemia in NICU. Dissertation Doctor of Medicine, 2006
5. Takkar VP, Bhakoo ON, Narang A., Scoring system for the prediction of early neonatal infections. Indian Pediatr 1974;11:597–600
6. Gomaa HHA, Udo EE, Rajaram U., Neonatal septicaemia in Al-Jahra hospital Kuwait:etiologic agents and antibioticsensitivity patterns. Med Princ Pract 2001;10:145–50
7. Puopolo KM., Bacterial and fungal Infection. In:Cloherty JP, Eichenwald EC, Hansen AR, Stark AR. Manual of Neonatal care. 7th edn. Philadelphia:Wolter Kluwer Lippincott; 2012:624–55
8. Rao PS, Baliga M, Shivananda PG., Bacteriology of neonatal septicaemia in a rural referral hospital in South India. J Trop Pediatr 1993;39:230–3
9. Karki S, Rai GK, Manandhar R., Bacteriological analysis and antibiotic sensitivity pattern of blood culture isolates in Kanti Children Hospital. J. Nepal Paediatr. Soc 2010;30:94–7
10. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; 23rd informational supplement. Pennsylvania:Clinical and Laboratory Standards Institute; 2013.p.M100–S23
11. Shrestha S, Adhikari N, Rai BK, Shreepaili A., Antibiotic resistance pattern of bacterial isolates in neonatal care unit. JNMA J Nepal Med Assoc 2010;50:277–81
12. Tallur SS, Kasturi AV, Nadigr SD, Krishna BV., Clinico-bacteriological study of neonatal septicemia in Hubli. Indian J Pediatr 2000;67:169–74
13. Shah A, Mulla S, Revdiwala S., Neonatal sepsis:high antibiotic resistance of the bacterial pathogens in a neonatal intensive care unit of a tertiary Care hospital. J Clin Neonatol 2012;1:72–5.
14. Dias E, Vigneshwaran P., The bacterial profile of neonatal septicaemia in a rural hospital in South India. J Clin Diagn Res [Serial Online] 2010;4:3327–30. December [cited:2016 Jan 2]; Available from http://www.jcdr.net/back_issues.asp?issn=097309x&year=2010&month=December&volume=4&issue=6&page=3327-3330&id=1008
15. Mahapatra A, Ghosh SK, Mishra S, et al Enterobacter cloacae:a predominant pathogen in neonatal septicaemia. Indian J Med Microbiol 2002;20:110–12
16. Jyothi P, Basavaraj MC, Basavaraj PV., Bacteriological profile of neonatal septicemia and antibiotic susceptibility pattern of the isolates. J Nat Sci Biol Med 2013;4:306–9
17. Rathod SD, Bhatia PV, Patel PH, et al Bacteriological analysis and resistance pattern among various culture isolates from neonatal septicemia at Tertiary Care Hospital, Ahmedabad. Natl J Med Res 2012;2:466–9
18. Bhat YR, Lewis LE., KE V, Bacterial isolates of early-onset neonatal sepsis and their antibiotic susceptibility pattern between 1998 and 2004:an audit from a center in India. Ital J Pediatr 2011;37:32
19. Sharma A, Kutty CV, Sabharwal U, et al Diagnostic and prognostic role of CRP and m-ESR in neonatal septicemia. Indian Pediatr 1993;30:347–50
20. Garg D, Agarwal N., Aetiology and presentation of neonatal septicaemia at Tertiary Care Hospital of Southern Rajasthan. Int J Med Sci Edu 2014;1:12–20
21. Rajendraprasad BM, Basavaraj KN, Antony B., Bacterial spectrum of neonatal septicemia with their antibiogram with reference to various predisposing factors in a tertiary care hospital in Southern India. Ann Trop Med Public Health 2013;6:96–9
22. Khatua SP, Das AK, Chattergee BD, et al Neonatal septicemia. Indian J Pediatr 1986;53:509–14
23. Sheth KV, Patel TK, Tripathi CB., Antibiotic sensitivity pattern in neonatal intensive care unit of a tertiary care hospital of India. Asian J Pharm Clin Res 2012;5:46–50
24. Nayak S, Rai R, Kumar VK, et al Distribution of microorganisms in neonatal sepsis and antimicrobial susceptibility patterns in a tertiary care hospital. Arch Med Health Sci 2014;2:136–9
25. Roy I, Jain A, Kumar M, Agarwal SK., Bacteriology of neonatal septicaemia in a tertiary care hospital of northern India. Indian J Med Microbiol 2002;20:156–9
26. Tsering DC, Chanchal L, Pal R, Kar S., Bacteriological profile of septicemia and the risk factors in neonates and infants in Sikkim. J Glob Infect Dis Infect 2011;3:42–5
27. Shah HY, Gadhavi HM, Shah VP, et al Antibiotics Susceptibility Patterns of Bacterial Isolates Among Neonatal Septicemia in Tertiary Care Hospital, Jamnagar, Gujarat. Global Research Analysis 2012;1:99–100
28. Chugh K, Aggarwal BB, Kaul VK, Arya SC., Bacteriological profile of neonatal septicemia. Indian J Pediatr 1988;55:961–5
29. Ballot DE, Nana T, Sriruttan C, Cooper PA., Bacterial bloodstream infections in neonates in a developing country. ISRN Pediatr 2012;2012:508512
30. Rahman S, Hameed A, Roghani MT, Ullah Z., Multidrug resistant neonatal sepsis in Peshawar, Pakistan. Arch Dis Child Fetal Neonatal Ed 2002;87:52–4
31. Shaw CK, Shaw P, Thapalial A., Neonatal sepsis bacterial isolates and antibiotic susceptibility patterns at a NICU in a tertiary care hospital in western Nepal:a retrospective analysis. Kathmandu Univ Med J (KUMJ) 2007;5:153–60
32. Raghunath D., Emerging antibiotic resistance in bacteria with special reference to India. J Biosci 2008;33:593–603
33. Abd El Hafez M, Khalaf NG, El Ahmady M, et al An outbreak of methicillin resistant Staphylococcus epidermidis among neonates in a hospital in Saudi Arabia. J Infect Dev Ctries 2011;5:692–9
34. Madavi D, Aziz F, Agrawal G., Clinico-bacteriological profile and antibiotic sensitivity pattern of neonatal septicaemia- a prospective observational study. Int J Cur Res Rev 2015;7:13–20
35. Jajoo M, Kapoor K, Garg LK, et al To study the incidence and risk factors of early onset neonatal sepsis in an out born neonatal intensive care unit of India. J Clin Neonatol 2015;4:91–5
36. Sharma D, Kumar C, Pandita A, et al Bacteriological profile and clinical predictors of ESBL neonatal sepsis. J Matern Fetal Neonatal Med 2016;29:567–70