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Volumn 12, Issue 5, 2016, Pages 595-602

A Comparative Study of Intravenous Immunoglobulin and Subcutaneous Immunoglobulin in Adult Patients with Primary Immunodeficiency Diseases: A Systematic Review and Meta-Analysis

Author keywords

efficacy; Intravenous immunoglobulin; primary immunodeficiency; safety; Subcutaneous immunoglobulin

Indexed keywords

ANTIBIOTIC AGENT; IMMUNOGLOBULIN; IMMUNOGLOBULIN G;

EID: 84961215659     PISSN: 1744666X     EISSN: 17448409     Source Type: Journal    
DOI: 10.1586/1744666X.2016.1155452     Document Type: Article
Times cited : (41)

References (49)
  • 1
    • 84855297376 scopus 로고    scopus 로고
    • Newborn screening for primary immunodeficiencies: Beyond SCID and XLA
    • Borte S, Wang N, Oskarsdóttir S, et al. Newborn screening for primary immunodeficiencies: beyond SCID and XLA. Ann N Y Acad Sci. 2011; 1246: 118-130.
    • (2011) Ann N y Acad Sci , vol.1246 , pp. 118-130
    • Borte, S.1    Wang, N.2    Oskarsdóttir, S.3
  • 2
    • 84871989178 scopus 로고    scopus 로고
    • Guidelines for newborn screening of primary immunodeficiency diseases
    • Borte S, vonDöbeln U, Hammarström L. Guidelines for newborn screening of primary immunodeficiency diseases. Curr Opin Hematol. 2013; 20: 48-54.
    • (2013) Curr Opin Hematol , vol.20 , pp. 48-54
    • Borte, S.1    Vondöbeln, U.2    Hammarström, L.3
  • 3
    • 77749314940 scopus 로고    scopus 로고
    • History of primary immunodeficiency diseases in Iran
    • Aghamohammadi A, Moin M, Rezaei N. History of primary immunodeficiency diseases in Iran. Iran J Pediatr. 2010; 20: 16.
    • (2010) Iran J Pediatr , vol.20 , pp. 16
    • Aghamohammadi, A.1    Moin, M.2    Rezaei, N.3
  • 5
    • 79957533995 scopus 로고    scopus 로고
    • Indications and safety of intravenous and subcutaneous immunoglobulin therapy
    • Rezaei N, Abolhassani H, Aghamohammadi A, et al. Indications and safety of intravenous and subcutaneous immunoglobulin therapy. Expert Rev Clin Immunol. 2011; 7: 301-306.
    • (2011) Expert Rev Clin Immunol , vol.7 , pp. 301-306
    • Rezaei, N.1    Abolhassani, H.2    Aghamohammadi, A.3
  • 6
    • 84907818238 scopus 로고    scopus 로고
    • Immunoglobulin replacement therapy for primary immunodeficiencies
    • Peter JG, Chapel H. Immunoglobulin replacement therapy for primary immunodeficiencies. Immunotherapy. 2014; 6: 853-869.
    • (2014) Immunotherapy , vol.6 , pp. 853-869
    • Peter, J.G.1    Chapel, H.2
  • 7
    • 4944262622 scopus 로고    scopus 로고
    • Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home
    • Gardulf A, Nicolay U, Asensio O, et al. Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home. J Allergy Clin Immunol. 2004; 114 (4): 936-942.
    • (2004) J Allergy Clin Immunol , vol.114 , Issue.4 , pp. 936-942
    • Gardulf, A.1    Nicolay, U.2    Asensio, O.3
  • 9
    • 84894299046 scopus 로고    scopus 로고
    • A new intravenous immunoglobulin (BIVIGAM®) for primary humoral immunodeficiency
    • Wasserman RL. A new intravenous immunoglobulin (BIVIGAM®) for primary humoral immunodeficiency. Expert Rev Clin Immunol. 2014; 10: 325-337.
    • (2014) Expert Rev Clin Immunol , vol.10 , pp. 325-337
    • Wasserman, R.L.1
  • 10
    • 42049096072 scopus 로고    scopus 로고
    • Principles of and advances in immunoglobulin replacement therapy for primary immunodeficiency
    • Berger M. Principles of and advances in immunoglobulin replacement therapy for primary immunodeficiency. Immunol Allergy Clin North Am. 2008; 28: 413-437.
    • (2008) Immunol Allergy Clin North Am , vol.28 , pp. 413-437
    • Berger, M.1
  • 11
    • 0025738608 scopus 로고
    • Home treatment of hypogammaglobulinaemia with subcutaneous gammaglobulin by rapid infusion
    • Hammarstrom L, Gardulf A, Edvard Smith CI. Home treatment of hypogammaglobulinaemia with subcutaneous gammaglobulin by rapid infusion. Lancet. 1991; 338: 162-166.
    • (1991) Lancet , vol.338 , pp. 162-166
    • Hammarstrom, L.1    Gardulf, A.2    Edvard Smith, C.I.3
  • 12
    • 0036751568 scopus 로고    scopus 로고
    • Express subcutaneous IgG infusions: Decreased time of delivery with maintained safety
    • Hansen S, Gustafson R, Smith C, et al. Express subcutaneous IgG infusions: decreased time of delivery with maintained safety. Clin Immunol. 2002; 104: 237-241.
    • (2002) Clin Immunol , vol.104 , pp. 237-241
    • Hansen, S.1    Gustafson, R.2    Smith, C.3
  • 13
    • 34247279262 scopus 로고    scopus 로고
    • Immunoglobulin treatment for primary antibody deficiencies: Advantages of the subcutaneous route
    • Gardulf A. Immunoglobulin treatment for primary antibody deficiencies: advantages of the subcutaneous route. BioDrugs. 2007; 21: 105-116.
    • (2007) Bio Drugs , vol.21 , pp. 105-116
    • Gardulf, A.1
  • 14
    • 0028857579 scopus 로고
    • Subcutaneous immunoglobulin replacement in patients with primary antibody deficiencies: Safety and costs
    • Gardulf A, Andersen V, Björkander J, et al. Subcutaneous immunoglobulin replacement in patients with primary antibody deficiencies: safety and costs. Lancet. 1995; 345: 365-369.
    • (1995) Lancet , vol.345 , pp. 365-369
    • Gardulf, A.1    Andersen, V.2    Björkander, J.3
  • 15
    • 0034073949 scopus 로고    scopus 로고
    • The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy
    • Chapel HM, Spickett GP, Ericson D, et al. The comparison of the efficacy and safety of intravenous versus subcutaneous immunoglobulin replacement therapy. J Clin Immunol. 2000; 20: 94-100.
    • (2000) J Clin Immunol , vol.20 , pp. 94-100
    • Chapel, H.M.1    Spickett, G.P.2    Ericson, D.3
  • 16
    • 34548665264 scopus 로고    scopus 로고
    • Safety and efficacy of subcutaneous human immunoglobulin in children with primary immunodeficiency
    • Fasth A, Nyström J. Safety and efficacy of subcutaneous human immunoglobulin in children with primary immunodeficiency. Acta Paediatr. 2007; 96: 1474-1478.
    • (2007) Acta Paediatr , vol.96 , pp. 1474-1478
    • Fasth, A.1    Nyström, J.2
  • 17
    • 84920263313 scopus 로고    scopus 로고
    • Current treatment options with immunoglobulin G for the individualization of care in patients with primary immunodeficiency disease
    • Jolles S, Orange JS, Gardulf A, et al. Current treatment options with immunoglobulin G for the individualization of care in patients with primary immunodeficiency disease. Clin Exp Immunol. 2015; 179: 146-160.
    • (2015) Clin Exp Immunol , vol.179 , pp. 146-160
    • Jolles, S.1    Orange, J.S.2    Gardulf, A.3
  • 18
    • 84878233844 scopus 로고    scopus 로고
    • Home-based subcutaneous immunoglobulin versus hospital-based intravenous immunoglobulin in treatment of primary antibody deficiencies: Systematic review and meta analysis
    • Abolhassani H, Sadaghiani MS, Aghamohammadi A, et al. Home-based subcutaneous immunoglobulin versus hospital-based intravenous immunoglobulin in treatment of primary antibody deficiencies: systematic review and meta analysis. J Clin Immunol. 2012; 32: 1180-1192.
    • (2012) J Clin Immunol , vol.32 , pp. 1180-1192
    • Abolhassani, H.1    Sadaghiani, M.S.2    Aghamohammadi, A.3
  • 19
    • 84885182424 scopus 로고    scopus 로고
    • Comparative study of subcutaneous versus intravenous IgG replacement therapy in pediatric patients with primary immunodeficiency diseases: A multicenter study in Argentina
    • Bezrodnik L, Gómez Raccio A, Belardinelli G, et al. Comparative study of subcutaneous versus intravenous IgG replacement therapy in pediatric patients with primary immunodeficiency diseases: a multicenter study in Argentina. J Clin Immunol. 2013; 33: 1216-1222.
    • (2013) J Clin Immunol , vol.33 , pp. 1216-1222
    • Bezrodnik, L.1    Gómez Raccio, A.2    Belardinelli, G.3
  • 20
    • 84880004959 scopus 로고    scopus 로고
    • Subcutaneous immunoglobulin (16 or 20%) therapy in obese patients with primary immunodeficiency: A retrospective analysis of administration by infusion pump or subcutaneous rapid push
    • Shapiro R. Subcutaneous immunoglobulin (16 or 20%) therapy in obese patients with primary immunodeficiency: a retrospective analysis of administration by infusion pump or subcutaneous rapid push. Clin Exp Immunol. 2013; 173: 365-371.
    • (2013) Clin Exp Immunol , vol.173 , pp. 365-371
    • Shapiro, R.1
  • 21
    • 84898850033 scopus 로고    scopus 로고
    • Efficacy and safety of IgPro20, a subcutaneous immunoglobulin, in Japanese patients with primary immunodeficiency diseases
    • Kanegane H, Imai K, Yamada M, et al. Efficacy and safety of IgPro20, a subcutaneous immunoglobulin, in Japanese patients with primary immunodeficiency diseases. J Clin Immunol. 2014; 34: 204-211.
    • (2014) J Clin Immunol , vol.34 , pp. 204-211
    • Kanegane, H.1    Imai, K.2    Yamada, M.3
  • 22
    • 84911979412 scopus 로고    scopus 로고
    • Intravenous and subcutaneous immunoglobulin replacement: A two-way road. Optimizing healthcare quality in patients with primary immunodeficiencies
    • Soler-Palacín P, Gasó-Gago I, Fernández-Polo A, et al. Intravenous and subcutaneous immunoglobulin replacement: a two-way road. Optimizing healthcare quality in patients with primary immunodeficiencies. J Clin Immunol. 2014; 34: 1015-1017.
    • (2014) J Clin Immunol , vol.34 , pp. 1015-1017
    • Soler-Palacín, P.1    Gasó-Gago, I.2    Fernández-Polo, A.3
  • 23
    • 84925491129 scopus 로고    scopus 로고
    • Subcutaneous immunoglobulin replacement therapy in patients with primary immunodeficiency in routine clinical practice: The VISPO prospective multicenter study
    • Vultaggio A, Azzari C, Milito C, et al. Subcutaneous immunoglobulin replacement therapy in patients with primary immunodeficiency in routine clinical practice: the VISPO prospective multicenter study. Clin Drug Investig. 2015; 35: 179-185.
    • (2015) Clin Drug Investig , vol.35 , pp. 179-185
    • Vultaggio, A.1    Azzari, C.2    Milito, C.3
  • 24
    • 84866740512 scopus 로고    scopus 로고
    • Efficacy, safety and pharmacokinetics of a novel subcutaneous immunoglobulin, evogam®, in primary immunodeficiency
    • Empson MB, Tang MLK, Pearce LKC, et al. Efficacy, safety and pharmacokinetics of a novel subcutaneous immunoglobulin, evogam®, in primary immunodeficiency. J Clin Immunol. 2012; 32: 897-906.
    • (2012) J Clin Immunol , vol.32 , pp. 897-906
    • Empson, M.B.1    Tang, M.L.K.2    Pearce, L.K.C.3
  • 25
    • 79961169672 scopus 로고    scopus 로고
    • Efficacy safety, and pharmacokinetics of a 10% liquid immune globulin preparation (GAMMAGARD LIQUID, 10%) administered subcutaneously in subjects with primary immunodeficiency disease
    • Wasserman RL, Melamed I, Kobrynski L, et al. Efficacy safety, and pharmacokinetics of a 10% liquid immune globulin preparation (GAMMAGARD LIQUID, 10%) administered subcutaneously in subjects with primary immunodeficiency disease. J Clin Immuno. 2011; 31: 323-331.
    • (2011) J Clin Immuno , vol.31 , pp. 323-331
    • Wasserman, R.L.1    Melamed, I.2    Kobrynski, L.3
  • 26
    • 80052617229 scopus 로고    scopus 로고
    • Efficacy and safety of Hizentra® in patients with primary immunodeficiency after a dose-equivalent switch from intravenous or subcutaneous replacement therapy
    • Jolles S, Bernatowska E, De Gracia J, et al. Efficacy and safety of Hizentra® in patients with primary immunodeficiency after a dose-equivalent switch from intravenous or subcutaneous replacement therapy. J Clin Immunol. 2011; 141: 90-102.
    • (2011) J Clin Immunol , vol.141 , pp. 90-102
    • Jolles, S.1    Bernatowska, E.2    De Gracia, J.3
  • 27
    • 80255138611 scopus 로고    scopus 로고
    • Efficacy and safety of subcutaneous vivaglobin® replacement therapy in previously untreated patients with primary immunodeficiency: A prospective, multicenter study
    • Borte M, Quinti I, Soresina A, et al. Efficacy and safety of subcutaneous vivaglobin® replacement therapy in previously untreated patients with primary immunodeficiency: a prospective, multicenter study. J Clin Immunol. 2011; 31: 952-961.
    • (2011) J Clin Immunol , vol.31 , pp. 952-961
    • Borte, M.1    Quinti, I.2    Soresina, A.3
  • 28
    • 79955837379 scopus 로고    scopus 로고
    • Pharmacokinetics of subcutaneous IgPro20 in patients with primary immunodeficiency
    • Wasserman RL, Melamed I, Nelson Jr. RP, et al. Pharmacokinetics of subcutaneous IgPro20 in patients with primary immunodeficiency. Clin Pharmacokinet. 2011; 50: 405-414.
    • (2011) Clin Pharmacokinet , vol.50 , pp. 405-414
    • Wasserman, R.L.1    Melamed, I.2    Nelson, R.P.3
  • 29
    • 77955738662 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of subcutaneous immune globulin (human), 10% caprylate/chromatography purified in patients with primary immunodeficiency disease
    • Wasserman RL1, Irani AM, Tracy J, et al. Pharmacokinetics and safety of subcutaneous immune globulin (human), 10% caprylate/chromatography purified in patients with primary immunodeficiency disease. Clin Exp Immunol. 2010; 161: 518-526.
    • (2010) Clin Exp Immunol , vol.161 , pp. 518-526
    • Wasserman, R.1    Irani, A.M.2    Tracy, J.3
  • 30
    • 77954393427 scopus 로고    scopus 로고
    • Home-based subcutaneous immunoglobulin G replacement therapy under real-life conditions in children and adults with antibody deficiency
    • Hoffmann F, Grimbacher B, Thiel J, et al. Home-based subcutaneous immunoglobulin G replacement therapy under real-life conditions in children and adults with antibody deficiency. Eur J Med Res. 2010; 15: 238.
    • (2010) Eur J Med Res , vol.15 , pp. 238
    • Hoffmann, F.1    Grimbacher, B.2    Thiel, J.3
  • 31
    • 77953535202 scopus 로고    scopus 로고
    • Subcutaneous immunoglobulin therapy by rapid push is preferred to infusion by pump: A retrospective analysis
    • Shapiro R. Subcutaneous immunoglobulin therapy by rapid push is preferred to infusion by pump: a retrospective analysis. J Clin Immuno. 2010; 30: 301-307.
    • (2010) J Clin Immuno , vol.30 , pp. 301-307
    • Shapiro, R.1
  • 32
    • 77957580751 scopus 로고    scopus 로고
    • Efficacy and safety of a new 20% immunoglobulin preparation for subcutaneous administration, IgPro20, in patients with primary immunodeficiency
    • Hagan JB, Fasano MB, Spector S, et al. Efficacy and safety of a new 20% immunoglobulin preparation for subcutaneous administration, IgPro20, in patients with primary immunodeficiency. J Clin Immuno. 2010; 30: 734-745.
    • (2010) J Clin Immuno , vol.30 , pp. 734-745
    • Hagan, J.B.1    Fasano, M.B.2    Spector, S.3
  • 33
    • 43049114886 scopus 로고    scopus 로고
    • Prospective study on CVID patients with adverse reactions to intravenous or subcutaneous IgG administration
    • Quinti I, Soresina A, Agostini C, et al. Prospective study on CVID patients with adverse reactions to intravenous or subcutaneous IgG administration. J Clin Immunol. 2008; 28: 263-267.
    • (2008) J Clin Immunol , vol.28 , pp. 263-267
    • Quinti, I.1    Soresina, A.2    Agostini, C.3
  • 34
    • 33745158644 scopus 로고    scopus 로고
    • Safety and tolerability of increased rate of infusion of intravenous immunoglobulin G, 10% in antibody-deficient patients
    • Gelfand EW, Hanna K. Safety and tolerability of increased rate of infusion of intravenous immunoglobulin G, 10% in antibody-deficient patients. J Clin Immunol. 2006; 26: 284-290.
    • (2006) J Clin Immunol , vol.26 , pp. 284-290
    • Gelfand, E.W.1    Hanna, K.2
  • 35
    • 33745145825 scopus 로고    scopus 로고
    • Safety and efficacy of self-administered subcutaneous immunoglobulin in patients with primary immunodeficiency diseases
    • Ochs HD, Gupta S, Kiessling P, et al. Safety and efficacy of self-administered subcutaneous immunoglobulin in patients with primary immunodeficiency diseases. J Clin Immunol. 2006; 26: 265-273.
    • (2006) J Clin Immunol , vol.26 , pp. 265-273
    • Ochs, H.D.1    Gupta, S.2    Kiessling, P.3
  • 36
    • 33745040276 scopus 로고    scopus 로고
    • Rapid subcutaneous IgG replacement therapy is effective and safe in children and adults with primary immunodeficiencies-a prospective, multi-national study
    • Gardulf A, Nicolay U, Asensio O, et al. Rapid subcutaneous IgG replacement therapy is effective and safe in children and adults with primary immunodeficiencies-a prospective, multi-national study. J Clin Immunol. 2006; 26: 177-185.
    • (2006) J Clin Immunol , vol.26 , pp. 177-185
    • Gardulf, A.1    Nicolay, U.2    Asensio, O.3
  • 37
    • 0141574289 scopus 로고    scopus 로고
    • Substitution therapy in immunodeficient patients with anti-IgA antibodies or severe adverse reactions to previous immunoglobulin therapy
    • Eijkhout H, Van Den Broek P, Van Der Meer J. Substitution therapy in immunodeficient patients with anti-IgA antibodies or severe adverse reactions to previous immunoglobulin therapy. Neth J Med. 2003; 61: 213-217.
    • (2003) Neth J Med , vol.61 , pp. 213-217
    • Eijkhout, H.1    Van Den Broek, P.2    Van Der Meer, J.3
  • 38
    • 0031871760 scopus 로고    scopus 로고
    • Immunoglobulin replacement treatment by rapid subcutaneous infusion
    • Gaspar J, Gerritsen B, Jones A. Immunoglobulin replacement treatment by rapid subcutaneous infusion. Arch Dis Child. 1998; 79: 48-51.
    • (1998) Arch Dis Child , vol.79 , pp. 48-51
    • Gaspar, J.1    Gerritsen, B.2    Jones, A.3
  • 39
    • 0031051617 scopus 로고    scopus 로고
    • Multicenter crossover comparison of the safety and efficacy of Intraglobin-F with Gamimune-N, Sandoglobulin, and Gammagard in patients with primary immunodeficiency diseases
    • Schiff RI, Williams LW, Nelson RP, et al. Multicenter crossover comparison of the safety and efficacy of Intraglobin-F with Gamimune-N, Sandoglobulin, and Gammagard in patients with primary immunodeficiency diseases. J Clin Immunol. 1997; 17: 21-28.
    • (1997) J Clin Immunol , vol.17 , pp. 21-28
    • Schiff, R.I.1    Williams, L.W.2    Nelson, R.P.3
  • 40
    • 84861443275 scopus 로고    scopus 로고
    • Immune globulin subcutaneous (Human) 20%: In primary immunodeficiency disorders
    • McCormack PL. Immune globulin subcutaneous (Human) 20%: in primary immunodeficiency disorders. Drugs. 2012; 72: 1087-1097.
    • (2012) Drugs , vol.72 , pp. 1087-1097
    • McCormack, P.L.1
  • 41
    • 16844365082 scopus 로고    scopus 로고
    • Therapeutic intravenous immunoglobulins
    • Lemieux R, Bazin R, Néron S. Therapeutic intravenous immunoglobulins. Mol Immunol. 2005; 42: 839-848.
    • (2005) Mol Immunol , vol.42 , pp. 839-848
    • Lemieux, R.1    Bazin, R.2    Néron, S.3
  • 42
    • 2942641966 scopus 로고    scopus 로고
    • Subcutaneous immunoglobulin replacement in primary immunodeficiencies
    • Berger M. Subcutaneous immunoglobulin replacement in primary immunodeficiencies. Clin Immunol. 2004; 112: 1-7.
    • (2004) Clin Immunol , vol.112 , pp. 1-7
    • Berger, M.1
  • 43
    • 17444424564 scopus 로고    scopus 로고
    • Pharmacoeconomic evaluation of immunoglobulin treatment in patients with antibody deficiencies from the perspective of the German statutory health insurance
    • Högy B, Keinecke HO, Borte M. Pharmacoeconomic evaluation of immunoglobulin treatment in patients with antibody deficiencies from the perspective of the German statutory health insurance. Eur J Health Econ. 2005; 6: 24-29.
    • (2005) Eur J Health Econ , vol.6 , pp. 24-29
    • Högy, B.1    Keinecke, H.O.2    Borte, M.3
  • 45
    • 30944444864 scopus 로고    scopus 로고
    • Health-related quality of life and treatment satisfaction in North American patients with primary immunedeficiency diseases receiving subcutaneous IgG self-infusions at home
    • Nicolay U, Kiessling P, Berger M, et al. Health-related quality of life and treatment satisfaction in North American patients with primary immunedeficiency diseases receiving subcutaneous IgG self-infusions at home. J Clin Immuno. 2006; 26: 65-72.
    • (2006) J Clin Immuno , vol.26 , pp. 65-72
    • Nicolay, U.1    Kiessling, P.2    Berger, M.3
  • 46
    • 53649104662 scopus 로고    scopus 로고
    • Economic assessment of different modalities of immunoglobulin replacement therapy
    • Membe SK, Ho C, Cimon K, et al. Economic assessment of different modalities of immunoglobulin replacement therapy. Immunol Allergy Clin North Am. 2008; 28: 861-874.
    • (2008) Immunol Allergy Clin North Am , vol.28 , pp. 861-874
    • Membe, S.K.1    Ho, C.2    Cimon, K.3
  • 47
    • 77950834217 scopus 로고    scopus 로고
    • Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency disease
    • Skoda-Smith S, Torgerson TR, Ochs HD. Subcutaneous immunoglobulin replacement therapy in the treatment of patients with primary immunodeficiency disease. Ther Clin Risk Manag. 2010; 6: 1.
    • (2010) Ther Clin Risk Manag , vol.6 , pp. 1
    • Skoda-Smith, S.1    Torgerson, T.R.2    Ochs, H.D.3
  • 48
    • 80255138608 scopus 로고    scopus 로고
    • Efficacy and safety of Hizentra ®, a new 20% immunoglobulin preparation for subcutaneous administration, in pediatric patients with primary immunodeficiency
    • Borte M, Pac M, Serban M, et al. Efficacy and safety of Hizentra ®, a new 20% immunoglobulin preparation for subcutaneous administration, in pediatric patients with primary immunodeficiency. J Clin Immunol. 2011; 31: 752-761.
    • (2011) J Clin Immunol , vol.31 , pp. 752-761
    • Borte, M.1    Pac, M.2    Serban, M.3
  • 49
    • 84880133655 scopus 로고    scopus 로고
    • An overview of subcutaneous vs. Intravenous immunoglobulin for primary immunodeficiencies: Systematic review and economic analysis
    • Ho C, Membe S, Cimon K. An overview of subcutaneous vs. intravenous immunoglobulin for primary immunodeficiencies: systematic review and economic analysis. CADTH. HTA. 2008; 36: 1-8.
    • (2008) CADTH. HTA , vol.36 , pp. 1-8
    • Ho, C.1    Membe, S.2    Cimon, K.3


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