Unique trophoblast stem cell- and pluripotency marker staining patterns depending on gestational age and placenta-associated pregnancy complications

Cell Adhesion and Migration

Volumn 10, Issue 1-2, 2016, Pages 56-65

  Weber, Maja ^a   Göhner, Claudia ^a,b   San Martin, Sebastian ^c   Vattai, Aurelia ^d   Hutter, Stefan ^d   Parraga, Mario ^c   Jeschke, Udo ^d   Schleussner, Ekkehard ^a   Markert, Udo R ^a   Fitzgerald, Justine S ^a,e  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c UNIVERSIDAD DE VALPARAÍSO   (Chile)

^d UNIVERSITY OF MUNICH   (Germany)

^e Kinderwunschzentrum Erfurt   (Germany)

Author keywords

IUGR; placenta; pluripotency markers; preeclampsia; trophoblast stem cell markers

Indexed keywords

BIOLOGICAL MARKER; OCT4A PROTEIN; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG;

ARTICLE; BLASTOCYST; CYTOTROPHOBLAST; FEMALE; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPEROXIDASE STAINING; INTRAUTERINE GROWTH RETARDATION; MESENCHYME CELL; PLACENTA; PLACENTA DISORDER; PLURIPOTENT STEM CELL; PREECLAMPSIA; PREGNANCY COMPLICATION; PROTEIN EXPRESSION; SYNCYTIOTROPHOBLAST; TROPHOBLAST; METABOLISM; PATHOLOGY; PREGNANCY; STAINING; THIRD TRIMESTER PREGNANCY;

BIOMARKERS; FEMALE; FETAL GROWTH RETARDATION; GESTATIONAL AGE; HUMANS; IMMUNOHISTOCHEMISTRY; PLACENTA; PLURIPOTENT STEM CELLS; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY TRIMESTER, THIRD; STAINING AND LABELING; TROPHOBLASTS;

EID: 84961201128     PISSN: 19336918     EISSN: 19336926     Source Type: Journal    
DOI: 10.1080/19336918.2016.1142035     Document Type: Article

References (32)

1. E.Berzan, R.Doyle, C.M.Brown. Treatment of preeclampsia: current approach and future perspectives. Curr Hypertension Rep 2014; 16:473; PMID:25135649; http://dx.doi.org/10.1007/s11906-014-0473-5
2. C.W.Redman, I.L.Sargent. Latest advances in understanding preeclampsia. Science 2005; 308:1592-4; PMID:15947178; http://dx.doi.org/10.1126/science.1111726
3. G.J.Burton, A.W.Woods, E.Jauniaux, J.C.Kingdom. Rheological and physiological consequences of conversion of the maternal spiral arteries for uteroplacental blood flow during human pregnancy. Placenta 2009; 30:473-82; PMID:19375795; http://dx.doi.org/10.1016/j.placenta.2009.02.009
4. F.Lyall. Priming and remodelling of human placental bed spiral arteries during pregnancy–a review. Placenta 2005; 26 Suppl A:S31-6; PMID:15837064; http://dx.doi.org/10.1016/j.placenta.2005.02.010
5. A.C.Staff, R.Dechend, R.Pijnenborg. Learning from the placenta: acute atherosis and vascular remodeling in preeclampsia-novel aspects for atherosclerosis and future cardiovascular health. Hypertension 2010; 56:1026-34; PMID:20956732; http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.157743
6. B.Huppertz. Placental origins of preeclampsia: challenging the current hypothesis. Hypertension 2008; 51:970-5; PMID:18259009; http://dx.doi.org/10.1161/HYPERTENSIONAHA.107.107607
7. C.W.Redman, I.L.Sargent. Immunology of pre-eclampsia. Am J Reprod Immunol 2010; 63:534-43; PMID:20331588; http://dx.doi.org/10.1111/j.1600-0897.2010.00831.x
8. B.C.Young, R.J.Levine, S.A.Karumanchi. Pathogenesis of preeclampsia. Ann Rev Pathol 2010; 5:173-92; PMID:20078220; http://dx.doi.org/10.1146/annurev-pathol-121808-102149
9. C.W.Redman, D.S.Tannetta, R.A.Dragovic, C.Gardiner, J.H.Southcombe, G.P.Collett, I.L.Sargent. Review: does size matter? Placental debris and the pathophysiology of pre-eclampsia. Placenta 2012; 33 Suppl:S48-54; PMID:22217911; http://dx.doi.org/10.1016/j.placenta.2011.12.006
10. S.Carolina, J.R.Pamela, C.N.Colleen. Exosomes in prostate cancer: putting together the pieces of a puzzle. Cancers 2013; 5:1522-44; PMID:24351670
11. T.M.Mayhew. A stereological perspective on placental morphology in normal and complicated pregnancies. J Anatomy 2009; 215:77-90; PMID:19141109; http://dx.doi.org/10.1111/j.1469-7580.2008.00994.x
12. O.Genbacev, J.D.Lamb, A.Prakobphol, M.Donne, M.T.McMaster, S.J.Fisher. Human trophoblast progenitors: where do they reside? Semin Reproduct Med 2013; 31:56-61; PMID:23329637; http://dx.doi.org/10.1055/s-0032-1331798
13. A.Rolfo, D.Giuffrida, A.M.Nuzzo, D.Pierobon, S.Cardaropoli, E.Piccoli, M.Giovarelli, T.Todros. Pro-inflammatory profile of preeclamptic placental mesenchymal stromal cells: new insights into the etiopathogenesis of preeclampsia. PloS One 2013; 8:e59403; PMID:23527185; http://dx.doi.org/10.1371/journal.pone.0059403
14. C.Salomon, J.Ryan, L.Sobrevia, M.Kobayashi, K.Ashman, M.Mitchell, G.E.Rice. Exosomal signaling during hypoxia mediates microvascular endothelial cell migration and vasculogenesis. PloS One 2013; 8:e68451; PMID:23861904; http://dx.doi.org/10.1371/journal.pone.0068451
15. S.M.Newhouse, S.T.Davidge, B.Winkler-Lowen, N.Demianczuk, L.J.Guilbert. In vitro differentiation of villous trophoblasts from pregnancies complicated by intrauterine growth restriction with and without pre-eclampsia. Placenta 2007; 28:999-1003; PMID:17559930; http://dx.doi.org/10.1016/j.placenta.2007.04.008
16. M.Hemberger, R.Udayashankar, P.Tesar, H.Moore, G.J.Burton. ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta. Hum Mol Gen 2010; 19:2456-67; PMID:20354077; http://dx.doi.org/10.1093/hmg/ddq128
17. O.Genbacev, M.Donne, M.Kapidzic, M.Gormley, J.Lamb, J.Gilmore, N.Larocque, G.Goldfien, T.Zdravkovic, M.T.McMaster, S.J.Fisher. Establishment of human trophoblast progenitor cell lines from the chorion. Stem cells (Dayton, Ohio) 2011; 29:1427-36; PMID:21755573
18. R.Arakawa, R.Aoki, M.Arakawa, K.Saito. Human first-trimester chorionic villi have a myogenic potential. Cell Tissue Res 2012; 348:189-97; PMID:22370594; http://dx.doi.org/10.1007/s00441-012-1340-9
19. G.N.Jones, D.Moschidou, T.I.Puga-Iglesias, K.Kuleszewicz, M.Vanleene, S.J.Shefelbine, G.Bou-Gharios, N.M.Fisk, A.L.David, P.De Coppi, P.V.Guillot. Ontological differences in first compared to third trimester human fetal placental chorionic stem cells. PloS One 2012; 7:e43395; PMID:22962584; http://dx.doi.org/10.1371/journal.pone.0043395
20. U.Jeschke, D.Mayr, B.Schiessl, I.Mylonas, S.Schulze, C.Kuhn, K.Friese, H.Walzel. Expression of galectin-1, -3 (gal-1, gal-3) and the Thomsen-Friedenreich (TF) antigen in normal, IUGR, preeclamptic and HELLP placentas. Placenta 2007; 28:1165-73; PMID:17664004; http://dx.doi.org/10.1016/j.placenta.2007.06.006
21. A.Honig, L.Rieger, M.Kapp, J.Dietl, U.Kammerer. Immunohistochemistry in human placental tissue–pitfalls of antigen detection. J Histochem Cytochem: Off J Histochem Soc 2005; 53:1413-20; PMID:16009964; http://dx.doi.org/10.1369/jhc.5A6664.2005
22. M.Weber, I.Knoefler, E.Schleussner, U.R.Markert, J.S.Fitzgerald. HTR8/SVneo cells display trophoblast progenitor cell-like characteristics indicative of self-renewal, repopulation activity, and expression of “stemness-” associated transcription factors. BioMed Res Int 2013; 2013:243649; PMID:23586024; http://dx.doi.org/10.1155/2013/243649
23. M.K.Siu, E.S.Wong, H.Y.Chan, H.Y.Ngan, K.Y.Chan, A.N.Cheung. Overexpression of NANOG in gestational trophoblastic diseases: effect on apoptosis, cell invasion, and clinical outcome. Am J Pathol 2008; 173:1165-72; PMID:18772339; http://dx.doi.org/10.2353/ajpath.2008.080288
24. S.Liedtke, M.Stephan, G.Kogler. Oct4 expression revisited: potential pitfalls for data misinterpretation in stem cell research. Biol Chem 2008; 389:845-50; PMID:18627312; http://dx.doi.org/10.1515/BC.2008.098
25. T.T.Gu, S.Y.Liu, P.S.Zheng. Cytoplasmic NANOG-positive stromal cells promote human cervical cancer progression. Am J Pathol 2012; 181:652-61; PMID:22683467; http://dx.doi.org/10.1016/j.ajpath.2012.04.008
26. W.Luo, S.Li, B.Peng, Y.Ye, X.Deng, K.Yao. Embryonic stem cells markers SOX2, OCT4 and Nanog expression and their correlations with epithelial-mesenchymal transition in nasopharyngeal carcinoma. PloS One 2013; 8:e56324; PMID:23424657; http://dx.doi.org/10.1371/journal.pone.0056324
27. C.S.Kao, S.Warren, M.T.Idrees. Merkel cell carcinoma exhibiting cytoplasmic OCT4 staining: a potential new diagnostic immunohistochemical marker. Am J Dermatopathol 2013; PMID:23291584
28. R.E.Alexander, L.Cheng, D.J.Grignon, M.Idrees. Cytoplasmic staining of OCT4 is a highly sensitive marker of adrenal medullary-derived tissue. Am J Surg Pathol 2013; 37:727-33; PMID:23588367; http://dx.doi.org/10.1097/PAS.0b013e3182793dc2
29. A.A.Avilion, S.K.Nicolis, L.H.Pevny, L.Perez, N.Vivian, R.Lovell-Badge. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev 2003; 17:126-40; PMID:12514105; http://dx.doi.org/10.1101/gad.224503
30. Z.E.Madeja, J.Sosnowski, K.Hryniewicz, E.Warzych, P.Pawlak, N.Rozwadowska, B.Plusa, D.Lechniak. Changes in sub-cellular localisation of trophoblast and inner cell mass specific transcription factors during bovine preimplantation development. BMC Dev Biol 2013; 13:32; PMID:23941255; http://dx.doi.org/10.1186/1471-213X-13-32
31. J.L.James, P.R.Stone, L.W.Chamley. The isolation and characterization of a population of extravillous trophoblast progenitors from first trimester human placenta. Hum Reproduct 2007; 22:2111-9; PMID:17580299; http://dx.doi.org/10.1093/humrep/dem144
32. M.Weber, C.Kuhn, S.Schulz, B.Schiessl, E.Schleussner, U.Jeschke, U.R.Markert, J.S.Fitzgerald. Expression of signal transducer and activator of transcription 3 (STAT3) and its activated forms is negatively altered in trophoblast and decidual stroma cells derived from preeclampsia placentae. Histopathology 2012; 60:657-62; PMID:22211353; http://dx.doi.org/10.1111/j.1365-2559.2011.04063.x