Fetal Gene Therapy for Ornithine Transcarbamylase Deficiency by Intrahepatic Plasmid DNA-Micro-Bubble Injection Combined with Hepatic Ultrasound Insonation

Ultrasound in Medicine and Biology

Volumn 42, Issue 6, 2016, Pages 1357-1361

  Oishi, Yoshie ^a   Kakimoto, Takashi ^a   Yuan, Wenji ^a   Kuno, Shuichi ^a   Yamashita, Hiromasa ^a   Chiba, Toshio ^a  

^a NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

Author keywords

Micro bubble; OTC deficient mouse; Plasmid DNA; Prenatal gene therapy; Sonotransfection; Ultrasound insonation

Indexed keywords

AMINO ACIDS; AMMONIA; BIOMOLECULES; BUBBLES (IN FLUIDS); GENE THERAPY; GENES; MAMMALS; MIXTURES; ULTRASONICS;

INSONATION; MICRO-BUBBLE; OTC DEFICIENT MOUSE; PLASMID DNA; SONOTRANSFECTION;

DNA;

AMMONIA; ORNITHINE CARBAMOYLTRANSFERASE; OROTIC ACID; PLASMID DNA;

AMMONIA BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVITY; FEMALE; FETUS; GENE THERAPY; MALE; MICROBUBBLE; MOUSE; NEWBORN; NONHUMAN; ORNITHINE TRANSCARBAMYLASE DEFICIENCY; ULTRASOUND; ANIMAL; BAGG ALBINO MOUSE; DISEASE MODEL; EMBRYOLOGY; GENETIC TRANSFECTION; LIVER; ORNITHINE CARBAMOYLTRANSFERASE DEFICIENCY DISEASE; PLASMID; PROCEDURES; THERAPEUTIC USE; ULTRASOUND THERAPY;

ANIMALS; ANIMALS, NEWBORN; DISEASE MODELS, ANIMAL; FEMALE; GENETIC THERAPY; LIVER; MALE; MICE; MICE, INBRED BALB C; MICROBUBBLES; ORNITHINE CARBAMOYLTRANSFERASE DEFICIENCY DISEASE; PLASMIDS; TRANSFECTION; ULTRASONIC THERAPY;

EID: 84961176989     PISSN: 03015629     EISSN: 1879291X     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2015.10.007     Document Type: Article

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