메뉴 건너뛰기




Volumn 11, Issue 2, 2016, Pages

Constitutively elevated blood serotonin is associated with bone loss and type 2 diabetes in rats

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CARBOXY TERMINAL TELOPEPTIDE; CHOLESTEROL; GLUCOSE; HEMOGLOBIN A1C; INSULIN; PARATHYROID HORMONE; SEROTONIN;

EID: 84961144159     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0150102     Document Type: Article
Times cited : (36)

References (48)
  • 1
    • 56349162283 scopus 로고    scopus 로고
    • Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum
    • PMID: 19041748
    • Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schutz G, et al. (2008) Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum. Cell 135: 825-837. doi: 10.1016/j.cell.2008.09.059 PMID: 19041748
    • (2008) Cell , vol.135 , pp. 825-837
    • Yadav, V.K.1    Ryu, J.H.2    Suda, N.3    Tanaka, K.F.4    Gingrich, J.A.5    Schutz, G.6
  • 2
    • 84867166343 scopus 로고    scopus 로고
    • FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin
    • PMID: 22945629
    • Kode A, Mosialou I, Silva BC, Rached MT, Zhou B, Wang J, et al. (2012) FOXO1 orchestrates the bone-suppressing function of gut-derived serotonin. J Clin Invest 122: 3490-3503. doi: 10.1172/JCI64906 PMID: 22945629
    • (2012) J Clin Invest , vol.122 , pp. 3490-3503
    • Kode, A.1    Mosialou, I.2    Silva, B.C.3    Rached, M.T.4    Zhou, B.5    Wang, J.6
  • 4
    • 84953836265 scopus 로고    scopus 로고
    • Adult tph2 knockout mice without brain serotonin have moderately elevated spine trabecular bone but moderately low cortical bone thickness
    • PMID: 26229596
    • Brommage R, Liu J, Doree D, Yu W, Powell DR, Melissa Yang Q (2015) Adult Tph2 knockout mice without brain serotonin have moderately elevated spine trabecular bone but moderately low cortical bone thickness. Bonekey Rep 4: 718. doi: 10.1038/bonekey.2015.87 PMID: 26229596
    • (2015) Bonekey Rep , vol.4 , pp. 718
    • Brommage, R.1    Liu, J.2    Doree, D.3    Yu, W.4    Powell, D.R.5    Melissa Yang, Q.6
  • 5
    • 84923897116 scopus 로고    scopus 로고
    • High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes
    • PMID: 26273529
    • Brommage R, Liu J, Hansen GM, Kirkpatrick LL, Potter DG, Sands AT, et al. (2014) High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes. Bone Res 2: 14034. doi: 10.1038/boneres.2014.34 PMID: 26273529
    • (2014) Bone Res , vol.2
    • Brommage, R.1    Liu, J.2    Hansen, G.M.3    Kirkpatrick, L.L.4    Potter, D.G.5    Sands, A.T.6
  • 6
    • 84890100598 scopus 로고    scopus 로고
    • Reversing LRP5-dependent osteoporosis and SOST deficiency-induced sclerosing bone disorders by altering WNT signaling activity
    • PMID: 23901037
    • Chang MK, Kramer I, Keller H, Gooi JH, Collett C, Jenkins D, et al. (2014) Reversing LRP5-dependent osteoporosis and SOST deficiency-induced sclerosing bone disorders by altering WNT signaling activity. J Bone Miner Res 29: 29-42. doi: 10.1002/jbmr.2059 PMID: 23901037
    • (2014) J Bone Miner Res , vol.29 , pp. 29-42
    • Chang, M.K.1    Kramer, I.2    Keller, H.3    Gooi, J.H.4    Collett, C.5    Jenkins, D.6
  • 8
    • 79960640529 scopus 로고    scopus 로고
    • Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high-bone-mass phenotype due to a mutation in lrp5
    • PMID: 21351148
    • Frost M, Andersen T, Gossiel F, Hansen S, Bollerslev J, van Hul W, et al. (2011) Levels of serotonin, sclerostin, bone turnover markers as well as bone density and microarchitecture in patients with high-bone-mass phenotype due to a mutation in Lrp5. J Bone Miner Res 26: 1721-1728. doi: 10.1002/jbmr.376 PMID: 21351148
    • (2011) J Bone Miner Res , vol.26 , pp. 1721-1728
    • Frost, M.1    Andersen, T.2    Gossiel, F.3    Hansen, S.4    Bollerslev, J.5    Van Hul, W.6
  • 9
    • 77953451716 scopus 로고    scopus 로고
    • Patients with high-bone-mass phenotype owing to lrp5-T253I mutation have low plasma levels of serotonin
    • PMID: 20200960
    • Frost M, Andersen TE, Yadav V, Brixen K, Karsenty G, Kassem M (2010) Patients with high-bone-mass phenotype owing to Lrp5-T253I mutation have low plasma levels of serotonin. J Bone Miner Res 25: 673-675. doi: 10.1002/jbmr.44 PMID: 20200960
    • (2010) J Bone Miner Res , vol.25 , pp. 673-675
    • Frost, M.1    Andersen, T.E.2    Yadav, V.3    Brixen, K.4    Karsenty, G.5    Kassem, M.6
  • 10
    • 84922395150 scopus 로고    scopus 로고
    • Lrp5 regulation of bone mass and serotonin synthesis in the gut
    • PMID: 25375916
    • Kode A, Obri A, Paone R, Kousteni S, Ducy P, Karsenty G (2014) Lrp5 regulation of bone mass and serotonin synthesis in the gut. Nat Med 20: 1228-1229. doi: 10.1038/nm.3698 PMID: 25375916
    • (2014) Nat Med , vol.20 , pp. 1228-1229
    • Kode, A.1    Obri, A.2    Paone, R.3    Kousteni, S.4    Ducy, P.5    Karsenty, G.6
  • 11
    • 84922393739 scopus 로고    scopus 로고
    • Reply to lrp5 regulation of bone mass and gut serotonin synthesis
    • PMID: 25375917
    • Cui Y, Niziolek PJ, MacDonald BT, Alenina N, Matthes S, Jacobsen CM, et al. (2014) Reply to Lrp5 regulation of bone mass and gut serotonin synthesis. Nat Med 20: 1229-1230. doi: 10.1038/nm.3697 PMID: 25375917
    • (2014) Nat Med , vol.20 , pp. 1229-1230
    • Cui, Y.1    Niziolek, P.J.2    MacDonald, B.T.3    Alenina, N.4    Matthes, S.5    Jacobsen, C.M.6
  • 12
    • 80054839269 scopus 로고    scopus 로고
    • High-bone-mass-producing mutations in the wnt signaling pathway resultin distinct skeletal phenotypes
    • PMID: 21855668
    • Niziolek PJ, Farmer TL, Cui Y, Turner CH, Warman ML, Robling AG (2011) High-bone-mass-producing mutations in the Wnt signaling pathway resultin distinct skeletal phenotypes. Bone 49: 1010-1019. doi: 10.1016/j.bone.2011.07.034 PMID: 21855668
    • (2011) Bone , vol.49 , pp. 1010-1019
    • Niziolek, P.J.1    Farmer, T.L.2    Cui, Y.3    Turner, C.H.4    Warman, M.L.5    Robling, A.G.6
  • 13
    • 84859512183 scopus 로고    scopus 로고
    • Mutations in LRP5cause primary osteoporosis without features of OI by reducing wnt signaling activity
    • PMID: 22487062
    • Korvala J, Juppner H, Makitie O, Sochett E, Schnabel D, Mora S, et al. (2012) Mutations in LRP5cause primary osteoporosis without features of OI by reducing Wnt signaling activity. BMC Med Genet 13: 26. doi: 10.1186/1471-2350-13-26 PMID: 22487062
    • (2012) BMC Med Genet , vol.13 , pp. 26
    • Korvala, J.1    Juppner, H.2    Makitie, O.3    Sochett, E.4    Schnabel, D.5    Mora, S.6
  • 14
    • 84897895220 scopus 로고    scopus 로고
    • Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5
    • PMID: 24038240
    • Lee GS, Simpson C, Sun BH, Yao C, Foer D, Sullivan B, et al. (2014) Measurement of plasma, serum, and platelet serotonin in individuals with high bone mass and mutations in LRP5. J Bone Miner Res 29: 976-981. doi: 10.1002/jbmr.2086 PMID: 24038240
    • (2014) J Bone Miner Res , vol.29 , pp. 976-981
    • Lee, G.S.1    Simpson, C.2    Sun, B.H.3    Yao, C.4    Foer, D.5    Sullivan, B.6
  • 15
    • 77953407628 scopus 로고    scopus 로고
    • Relation of serum serotonin levels to bone density and structural parameters in women
    • PMID: 19594297
    • Modder UI, Achenbach SJ, Amin S, Riggs BL, Melton LJ 3rd, Khosla S (2010) Relation of serum serotonin levels to bone density and structural parameters in women. J Bone Miner Res 25: 415-422. doi: 10.1359/jbmr.090721 PMID: 19594297
    • (2010) J Bone Miner Res , vol.25 , pp. 415-422
    • Modder, U.I.1    Achenbach, S.J.2    Amin, S.3    Riggs, B.L.4    Melton, L.J.5    Khosla, S.6
  • 16
    • 84953344323 scopus 로고    scopus 로고
    • The associations of serum serotonin with bone traits are age-and gender-specific
    • PMID: 25279460
    • Wang Q, Chen D, Nicholson P, Cheng S, Alen M, Mao L (2014) The associations of serum serotonin with bone traits are age-and gender-specific. PLoS One 9: e109028. doi: 10.1371/journal.pone.0109028 PMID: 25279460
    • (2014) PLoS One , vol.9
    • Wang, Q.1    Chen, D.2    Nicholson, P.3    Cheng, S.4    Alen, M.5    Mao, L.6
  • 18
    • 19344364877 scopus 로고    scopus 로고
    • Serotonin transporter kinetics in rats selected for extreme values of platelet serotonin level
    • PMID: 15894014
    • Cicin-Sain L, Froebe A, Bordukalo-Niksic T, Jernej B (2005) Serotonin transporter kinetics in rats selected for extreme values of platelet serotonin level. Life Sci 77: 452-461. PMID: 15894014
    • (2005) Life Sci , vol.77 , pp. 452-461
    • Cicin-Sain, L.1    Froebe, A.2    Bordukalo-Niksic, T.3    Jernej, B.4
  • 19
    • 0025336656 scopus 로고
    • Platelet serotonin level in rats is under genetic control
    • PMID: 2367601
    • Jernej B, Cicin-Sain L (1990) Platelet serotonin level in rats is under genetic control. Psychiatry Res 32: 167-174. PMID: 2367601
    • (1990) Psychiatry Res , vol.32 , pp. 167-174
    • Jernej, B.1    Cicin-Sain, L.2
  • 20
    • 0032458126 scopus 로고    scopus 로고
    • Serotonin transporter on rat platelets: Levels of mRNA underlie inherited differences in uptake kinetics
    • PMID: 10098721
    • Jernej B, Hranilovic D, Cicin-Sain L (1998) Serotonin transporter on rat platelets: levels of mRNA underlie inherited differences in uptake kinetics. Neurochem Int 33: 519-523. PMID: 10098721
    • (1998) Neurochem Int , vol.33 , pp. 519-523
    • Jernej, B.1    Hranilovic, D.2    Cicin-Sain, L.3
  • 21
    • 0035813621 scopus 로고    scopus 로고
    • "Type III" cells of rat taste buds: Immunohistochemical and ultrastructural studies of neuron-specific enolase, protein gene product 9.5, and serotonin
    • PMID: 11745610
    • Yee CL, Yang R, Bottger B, Finger TE, Kinnamon JC (2001) "Type III" cells of rat taste buds: immunohistochemical and ultrastructural studies of neuron-specific enolase, protein gene product 9.5, and serotonin. J Comp Neurol 440: 97-108. PMID: 11745610
    • (2001) J Comp Neurol , vol.440 , pp. 97-108
    • Yee, C.L.1    Yang, R.2    Bottger, B.3    Finger, T.E.4    Kinnamon, J.C.5
  • 22
    • 77249138271 scopus 로고    scopus 로고
    • 5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the Guinea pig ileum
    • PMID: 20007849
    • Foong JP, Parry LJ, Gwynne RM, Bornstein JC (2010) 5-HT(1A), SST(1), and SST(2) receptors mediate inhibitory postsynaptic potentials in the submucous plexus of the guinea pig ileum. Am J Physiol Gastrointest Liver Physiol 298: G384-394. doi: 10.1152/ajpgi.00438.2009 PMID: 20007849
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298 , pp. G384-G394
    • Foong, J.P.1    Parry, L.J.2    Gwynne, R.M.3    Bornstein, J.C.4
  • 23
    • 33645813684 scopus 로고    scopus 로고
    • Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption
    • PMID: 16798745
    • Simic P, Culej JB, Orlic I, Grgurevic L, Draca N, Spaventi R, et al. (2006) Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption. J Biol Chem 281: 25509-25521. PMID: 16798745
    • (2006) J Biol Chem , vol.281 , pp. 25509-25521
    • Simic, P.1    Culej, J.B.2    Orlic, I.3    Grgurevic, L.4    Draca, N.5    Spaventi, R.6
  • 24
    • 0023506286 scopus 로고
    • Effects of 1 alpha, 25-and24R, 25-dihydroxyvitamin D3 on aluminum-induced rickets in growing uremic rats
    • PMID: 3502683
    • Vukicevic S, Krempien B, Stavljenic A (1987) Effects of 1 alpha, 25-and24R, 25-dihydroxyvitamin D3 on aluminum-induced rickets in growing uremic rats. J Bone Miner Res 2: 533-545. PMID: 3502683
    • (1987) J Bone Miner Res , vol.2 , pp. 533-545
    • Vukicevic, S.1    Krempien, B.2    Stavljenic, A.3
  • 25
  • 26
    • 81755162303 scopus 로고    scopus 로고
    • Expression and localization of paxillin in rat pancreas during development
    • PMID: 22110278
    • Guo J, Liu LJ, Yuan L, Wang N, De W (2011) Expression and localization of paxillin in rat pancreas during development. World J Gastroenterol 17: 4479-4487. doi: 10.3748/wjg.v17.i40.4479 PMID: 22110278
    • (2011) World J Gastroenterol , vol.17 , pp. 4479-4487
    • Guo, J.1    Liu, L.J.2    Yuan, L.3    Wang, N.4    De, W.5
  • 27
    • 84899756898 scopus 로고    scopus 로고
    • Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine
    • PMID: 23749550
    • Margolis KG, Stevanovic K, Li Z, Yang QM, Oravecz T, Zambrowicz B, et al. (2014) Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine. Gut 63: 928-937. doi: 10.1136/gutjnl-2013-304901 PMID: 23749550
    • (2014) Gut , vol.63 , pp. 928-937
    • Margolis, K.G.1    Stevanovic, K.2    Li, Z.3    Yang, Q.M.4    Oravecz, T.5    Zambrowicz, B.6
  • 28
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-delta delta C(T)) method
    • PMID: 11846609
    • Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408. PMID: 11846609
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 29
    • 70350520200 scopus 로고    scopus 로고
    • Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation
    • PMID: 19859528
    • Paulmann N, Grohmann M, Voigt JP, Bert B, Vowinckel J, Bader M, et al. (2009) Intracellular serotonin modulates insulin secretion from pancreatic beta-cells by protein serotonylation. PLoS Biol 7: e1000229. doi: 10.1371/journal.pbio.1000229 PMID: 19859528
    • (2009) PLoS Biol , vol.7
    • Paulmann, N.1    Grohmann, M.2    Voigt, J.P.3    Bert, B.4    Vowinckel, J.5    Bader, M.6
  • 30
    • 0024334946 scopus 로고
    • Formal demonstration of the phosphorylation of rat brain tryptophan hydroxylase by ca2+/calmodulin-dependent protein kinase
    • PMID: 2542452
    • Ehret M, Cash CD, Hamon M, Maitre M (1989) Formal demonstration of the phosphorylation of rat brain tryptophan hydroxylase by Ca2+/calmodulin-dependent protein kinase. J Neurochem 52: 1886-1891. PMID: 2542452
    • (1989) J Neurochem , vol.52 , pp. 1886-1891
    • Ehret, M.1    Cash, C.D.2    Hamon, M.3    Maitre, M.4
  • 31
    • 0023732597 scopus 로고
    • Bone density of the radius, spine, and proximal femur in osteoporosis
    • PMID: 3213603
    • Mazess RB, Barden H, Ettinger M, Schultz E (1988) Bone density of the radius, spine, and proximal femur in osteoporosis. J Bone Miner Res 3: 13-18. PMID: 3213603
    • (1988) J Bone Miner Res , vol.3 , pp. 13-18
    • Mazess, R.B.1    Barden, H.2    Ettinger, M.3    Schultz, E.4
  • 32
    • 12344309568 scopus 로고    scopus 로고
    • Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight
    • PMID: 15125798
    • Lang T, LeBlanc A, Evans H, Lu Y, Genant H, Yu A (2004) Cortical and trabecular bone mineral loss from the spine and hip in long-duration spaceflight. J Bone Miner Res 19: 1006-1012. PMID: 15125798
    • (2004) J Bone Miner Res , vol.19 , pp. 1006-1012
    • Lang, T.1    LeBlanc, A.2    Evans, H.3    Lu, Y.4    Genant, H.5    Yu, A.6
  • 33
    • 0029940255 scopus 로고    scopus 로고
    • Differential responses of femoral and vertebral bones to long-term excessive L-thyroxine administration in adult rats
    • PMID: 8664988
    • Suwanwalaikorn S, Ongphiphadhanakul B, Braverman LE, Baran DT (1996) Differential responses of femoral and vertebral bones to long-term excessive L-thyroxine administration in adult rats. Eur J Endocrinol 134: 655-659. PMID: 8664988
    • (1996) Eur J Endocrinol , vol.134 , pp. 655-659
    • Suwanwalaikorn, S.1    Ongphiphadhanakul, B.2    Braverman, L.E.3    Baran, D.T.4
  • 34
    • 0031792583 scopus 로고    scopus 로고
    • Thyroid hormone excess increases insulin-like growth factor I transcripts in bone marrow cell cultures: Divergent effects on vertebral and femoral cell cultures
    • PMID: 9564868
    • Milne M, Kang MI, Quail JM, Baran DT (1998) Thyroid hormone excess increases insulin-like growth factor I transcripts in bone marrow cell cultures: divergent effects on vertebral and femoral cell cultures. Endocrinology 139: 2527-2534. PMID: 9564868
    • (1998) Endocrinology , vol.139 , pp. 2527-2534
    • Milne, M.1    Kang, M.I.2    Quail, J.M.3    Baran, D.T.4
  • 35
    • 77954480533 scopus 로고    scopus 로고
    • Serotonin regulates pancreatic beta cell mass during pregnancy
    • PMID: 20581837
    • Kim H, Toyofuku Y, Lynn FC, Chak E, Uchida T, Mizukami H, et al. (2010) Serotonin regulates pancreatic beta cell mass during pregnancy. Nat Med 16: 804-808. doi: 10.1038/nm.2173 PMID: 20581837
    • (2010) Nat Med , vol.16 , pp. 804-808
    • Kim, H.1    Toyofuku, Y.2    Lynn, F.C.3    Chak, E.4    Uchida, T.5    Mizukami, H.6
  • 36
    • 84887488911 scopus 로고    scopus 로고
    • Reduced serum concentrations of carboxylated and undercarboxylated osteocalcin are associated with risk of developing type 2 diabetes mellitus in a high cardiovascular risk population: A nested case-control study
    • PMID: 24037881
    • Diaz-Lopez A, Bullo M, Juanola-Falgarona M, Martinez-Gonzalez MA, Estruch R, Covas MI, et al. (2013) Reduced serum concentrations of carboxylated and undercarboxylated osteocalcin are associated with risk of developing type 2 diabetes mellitus in a high cardiovascular risk population: a nested case-control study. J Clin Endocrinol Metab 98: 4524-4531. doi: 10.1210/jc.2013-2472 PMID: 24037881
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 4524-4531
    • Diaz-Lopez, A.1    Bullo, M.2    Juanola-Falgarona, M.3    Martinez-Gonzalez, M.A.4    Estruch, R.5    Covas, M.I.6
  • 37
    • 84897904635 scopus 로고    scopus 로고
    • In vivo assessment of bone quality in postmenopausal women with type 2 diabetes
    • PMID: 24123088
    • Farr JN, Drake MT, Amin S, Melton LJ 3rd, McCready LK, Khosla S (2014) In vivo assessment of bone quality in postmenopausal women with type 2 diabetes. J Bone Miner Res 29: 787-795. doi: 10.1002/jbmr.2106 PMID: 24123088
    • (2014) J Bone Miner Res , vol.29 , pp. 787-795
    • Farr, J.N.1    Drake, M.T.2    Amin, S.3    Melton, L.J.4    McCready, L.K.5    Khosla, S.6
  • 38
    • 84872580066 scopus 로고    scopus 로고
    • Life without peripheral serotonin: Insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks
    • PMID: 23336045
    • Amireault P, Sibon D, Cote F (2013) Life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks. ACS Chem Neurosci 4: 64-71. doi: 10.1021/cn300154j PMID: 23336045
    • (2013) ACS Chem Neurosci , vol.4 , pp. 64-71
    • Amireault, P.1    Sibon, D.2    Cote, F.3
  • 39
    • 12344313055 scopus 로고    scopus 로고
    • Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth
    • PMID: 15539550
    • Warden SJ, Robling AG, Sanders MS, Bliziotes MM, Turner CH (2005) Inhibition of the serotonin (5-hydroxytryptamine) transporter reduces bone accrual during growth. Endocrinology 146: 685-693. PMID: 15539550
    • (2005) Endocrinology , vol.146 , pp. 685-693
    • Warden, S.J.1    Robling, A.G.2    Sanders, M.S.3    Bliziotes, M.M.4    Turner, C.H.5
  • 40
    • 0015862640 scopus 로고
    • Growth hormone regulation by melatonin and serotonin
    • PMID: 4583097
    • Smythe GA, Lazarus L (1973) Growth hormone regulation by melatonin and serotonin. Nature 244: 230-231. PMID: 4583097
    • (1973) Nature , vol.244 , pp. 230-231
    • Smythe, G.A.1    Lazarus, L.2
  • 41
    • 12344334748 scopus 로고    scopus 로고
    • Serotonin regulates osteoclast differentiation through its transporter
    • PMID: 15312242
    • Battaglino R, Fu J, Spate U, Ersoy U, Joe M, Sedaghat L, et al. (2004) Serotonin regulates osteoclast differentiation through its transporter. J Bone Miner Res 19: 1420-1431. PMID: 15312242
    • (2004) J Bone Miner Res , vol.19 , pp. 1420-1431
    • Battaglino, R.1    Fu, J.2    Spate, U.3    Ersoy, U.4    Joe, M.5    Sedaghat, L.6
  • 43
    • 39149118317 scopus 로고    scopus 로고
    • Tryptophan hydroxylase is modulated by L-type calcium channels in the rat pineal gland
    • PMID: 18221757
    • Barbosa R, Scialfa JH, Terra IM, Cipolla-Neto J, Simonneaux V, Afeche SC (2008) Tryptophan hydroxylase is modulated by L-type calcium channels in the rat pineal gland. Life Sci 82: 529-535. doi: 10.1016/j.lfs.2007.12.011 PMID: 18221757
    • (2008) Life Sci , vol.82 , pp. 529-535
    • Barbosa, R.1    Scialfa, J.H.2    Terra, I.M.3    Cipolla-Neto, J.4    Simonneaux, V.5    Afeche, S.C.6
  • 44
    • 13244292476 scopus 로고    scopus 로고
    • Different properties of the central and peripheral forms of human tryptophan hydroxylase
    • PMID: 15663479
    • McKinney J, Knappskog PM, Haavik J (2005) Different properties of the central and peripheral forms of human tryptophan hydroxylase. J Neurochem 92: 311-320. PMID: 15663479
    • (2005) J Neurochem , vol.92 , pp. 311-320
    • McKinney, J.1    Knappskog, P.M.2    Haavik, J.3
  • 45
    • 84901851788 scopus 로고    scopus 로고
    • Vitamin D hormone regulates serotonin synthesis. Part 1: Relevance for autism
    • PMID: 24558199
    • Patrick RP, Ames BN (2014) Vitamin D hormone regulates serotonin synthesis. Part 1: relevance for autism. FASEB J 28: 2398-2413. doi: 10.1096/fj.13-246546 PMID: 24558199
    • (2014) FASEB J , vol.28 , pp. 2398-2413
    • Patrick, R.P.1    Ames, B.N.2
  • 47
    • 84879926338 scopus 로고    scopus 로고
    • Circulating serotonin and bone density, structure, and turnover in carcinoid syndrome
    • PMID: 23633214
    • Walsh JS, Newell-Price JD, DeBono M, Adaway J, Keevil B, Eastell R (2013) Circulating serotonin and bone density, structure, and turnover in carcinoid syndrome. J Clin Endocrinol Metab 98: 2902-2907. doi: 10.1210/jc.2012-4174 PMID: 23633214
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. 2902-2907
    • Walsh, J.S.1    Newell-Price, J.D.2    DeBono, M.3    Adaway, J.4    Keevil, B.5    Eastell, R.6
  • 48
    • 84918568550 scopus 로고    scopus 로고
    • The rational use of animal models in the evaluation of novel bone regenerative therapies
    • Peric M, Dumic-Cule I, Grcevic D, Matijasic M, Verbanac D, Paul R, et al. (2015) The rational use of animal models in the evaluation of novel bone regenerative therapies. Bone 70C: 73-86.
    • (2015) Bone , vol.70 C , pp. 73-86
    • Peric, M.1    Dumic-Cule, I.2    Grcevic, D.3    Matijasic, M.4    Verbanac, D.5    Paul, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.