메뉴 건너뛰기




Volumn 32, Issue 8, 2016, Pages 986.e17-986.e22

Novel Oral Anticoagulants and the Risk of Major Hemorrhage in Elderly Patients With Chronic Kidney Disease: A Nested Case-Control Study

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTIFUNGAL AGENT; ANTITHROMBOCYTIC AGENT; CORTICOSTEROID; DABIGATRAN; RIVAROXABAN; SEROTONIN UPTAKE INHIBITOR; WARFARIN;

EID: 84960862119     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cjca.2016.01.013     Document Type: Article
Times cited : (22)

References (34)
  • 1
    • 84904634733 scopus 로고    scopus 로고
    • Dabigatran: how the drug company withheld important analyses
    • 1 Cohen, D., Dabigatran: how the drug company withheld important analyses. BMJ, 349, 2014, g4670.
    • (2014) BMJ , vol.349 , pp. g4670
    • Cohen, D.1
  • 2
    • 84882909945 scopus 로고    scopus 로고
    • Novel oral anticoagulants: clinical pharmacology, indications and practical considerations
    • 2 Harder, S., Graff, J., Novel oral anticoagulants: clinical pharmacology, indications and practical considerations. Eur J Clin Pharmacol 69 (2013), 1617–1633.
    • (2013) Eur J Clin Pharmacol , vol.69 , pp. 1617-1633
    • Harder, S.1    Graff, J.2
  • 3
    • 82455162521 scopus 로고    scopus 로고
    • The contribution of chronic kidney disease to the global burden of major noncommunicable diseases
    • 3 Couser, W.G., Remuzzi, G., Mendis, S., Tonelli, M., The contribution of chronic kidney disease to the global burden of major noncommunicable diseases. Kidney Int 80 (2011), 1258–1270.
    • (2011) Kidney Int , vol.80 , pp. 1258-1270
    • Couser, W.G.1    Remuzzi, G.2    Mendis, S.3    Tonelli, M.4
  • 4
    • 84871970168 scopus 로고    scopus 로고
    • Impact of chronic kidney disease on risk of incident atrial fibrillation and subsequent survival in Medicare patients
    • 4 Nelson, S.E., Shroff, G.R., Li, S., Herzog, C.A., Impact of chronic kidney disease on risk of incident atrial fibrillation and subsequent survival in Medicare patients. J Am Heart Assoc, 1, 2012, e002097.
    • (2012) J Am Heart Assoc , vol.1 , pp. e002097
    • Nelson, S.E.1    Shroff, G.R.2    Li, S.3    Herzog, C.A.4
  • 5
    • 84867582089 scopus 로고    scopus 로고
    • Association of mild to moderate chronic kidney disease with venous thromboembolism: pooled analysis of five prospective general population cohorts
    • 5 Mahmoodi, B.K., Gansevoort, R.T., Naess, I.A., et al. Association of mild to moderate chronic kidney disease with venous thromboembolism: pooled analysis of five prospective general population cohorts. Circulation 126 (2012), 1964–1971.
    • (2012) Circulation , vol.126 , pp. 1964-1971
    • Mahmoodi, B.K.1    Gansevoort, R.T.2    Naess, I.A.3
  • 6
    • 84888241102 scopus 로고    scopus 로고
    • Prescribing patterns of novel oral anticoagulants following regulatory approval for atrial fibrillation in Ontario, Canada: a population-based descriptive analysis
    • 6 Xu, Y., Holbrook, A.M., Simpson, C.S., Dowlatshahi, D., Johnson, A.P., Prescribing patterns of novel oral anticoagulants following regulatory approval for atrial fibrillation in Ontario, Canada: a population-based descriptive analysis. CMAJ Open 1 (2013), E115–E119.
    • (2013) CMAJ Open , vol.1 , pp. E115-E119
    • Xu, Y.1    Holbrook, A.M.2    Simpson, C.S.3    Dowlatshahi, D.4    Johnson, A.P.5
  • 7
    • 84895545893 scopus 로고    scopus 로고
    • FDA approved drug products: label information for PRADAXA
    • Available at: Accessed August 12, 2014
    • 7 FDA approved drug products: label information for PRADAXA. 2012 Available at: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022512s009lbl.pdf. Accessed August 12, 2014.
    • (2012)
  • 8
    • 72449133295 scopus 로고    scopus 로고
    • FDA approved drug products: Xarelto
    • Available at: Accessed August 12, 2014
    • 8 FDA approved drug products: Xarelto. 2012 Available at: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022406s001s002s003lbl.pdf. Accessed August 12, 2014.
    • (2012)
  • 9
    • 84990006460 scopus 로고    scopus 로고
    • Health Canada: Drugs and Health Products: Pradax
    • Available at: Accessed August 12, 2014
    • 9 Health Canada: Drugs and Health Products: Pradax. 2012 Available at: http://www.hc-sc.gc.ca/dhp-mps/prodpharma/sbd-smd/drugmed/ sbd_smd_2008_pradax_114887-eng.php. Accessed August 12, 2014.
    • (2012)
  • 10
    • 84990006460 scopus 로고    scopus 로고
    • Health Canada: Drugs and Health Products: Xarelto
    • Available at: Accessed August 12, 2014
    • 10 Health Canada: Drugs and Health Products: Xarelto. 2012 Available at: http://www.hc-sc.gc.ca/dhp-mps/prodpharma/sbd-smd/drug-med/sbd_smd_2009_xarelto_119111-eng.php. Accessed August 12, 2014.
    • (2012)
  • 11
    • 84880283344 scopus 로고    scopus 로고
    • Product Information: Pradaxa
    • Available at: Accessed August 12, 2014
    • 11 European Medicines Agency, Product Information: Pradaxa. 2012 Available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000829/WC500041059.pdf. Accessed August 12, 2014.
    • (2012)
    • European Medicines Agency1
  • 12
    • 84990012780 scopus 로고    scopus 로고
    • European Medicines Agency. Product Information: Xarelto. Available at: Accessed August 12.
    • 12 European Medicines Agency. Product Information: Xarelto. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000944/WC500057108.pdf. Accessed August 12, 2014.
    • (2014)
  • 13
    • 84873105205 scopus 로고    scopus 로고
    • Hemorrhagic gastritis with dabigatran in a patient with renal insufficiency
    • 13 Fellows, S.E., Rosini, J.M., Curtis, J.A., Volz, E.G., Hemorrhagic gastritis with dabigatran in a patient with renal insufficiency. J Emerg Med 44 (2013), e221–e225.
    • (2013) J Emerg Med , vol.44 , pp. e221-e225
    • Fellows, S.E.1    Rosini, J.M.2    Curtis, J.A.3    Volz, E.G.4
  • 14
    • 84859703006 scopus 로고    scopus 로고
    • Dabigatran-induced gastrointestinal bleeding in an elderly patient with moderate renal impairment
    • 14 Wychowski, M.K., Kouides, P.A., Dabigatran-induced gastrointestinal bleeding in an elderly patient with moderate renal impairment. Ann Pharmacother, 46, 2012, e10.
    • (2012) Ann Pharmacother , vol.46 , pp. e10
    • Wychowski, M.K.1    Kouides, P.A.2
  • 15
    • 35848948166 scopus 로고    scopus 로고
    • The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies
    • 15 von Elm, E., Altman, D.G., Egger, M., et al. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Ann Intern Med 147 (2007), 573–577.
    • (2007) Ann Intern Med , vol.147 , pp. 573-577
    • von Elm, E.1    Altman, D.G.2    Egger, M.3
  • 16
    • 84873326583 scopus 로고    scopus 로고
    • Rates of hemorrhage during warfarin therapy for atrial fibrillation
    • 16 Gomes, T., Mamdani, M.M., Holbrook, A.M., et al. Rates of hemorrhage during warfarin therapy for atrial fibrillation. CMAJ 185 (2013), E121–E127.
    • (2013) CMAJ , vol.185 , pp. E121-E127
    • Gomes, T.1    Mamdani, M.M.2    Holbrook, A.M.3
  • 17
    • 84876796876 scopus 로고    scopus 로고
    • No increase in adverse events during aliskiren use among Ontario patients receiving angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers
    • 17 Gilbert, C.J., Gomes, T., Mamdani, M.M., et al. No increase in adverse events during aliskiren use among Ontario patients receiving angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers. Can J Cardiol 29 (2013), 586–591.
    • (2013) Can J Cardiol , vol.29 , pp. 586-591
    • Gilbert, C.J.1    Gomes, T.2    Mamdani, M.M.3
  • 18
    • 84875861528 scopus 로고    scopus 로고
    • Detecting chronic kidney disease in population-based administrative databases using an algorithm of hospital encounter and physician claim codes
    • 18 Fleet, J.L., Dixon, S.N., Shariff, S.Z., et al. Detecting chronic kidney disease in population-based administrative databases using an algorithm of hospital encounter and physician claim codes. BMC Nephrol, 14, 2013, 81.
    • (2013) BMC Nephrol , vol.14 , pp. 81
    • Fleet, J.L.1    Dixon, S.N.2    Shariff, S.Z.3
  • 19
    • 33744506249 scopus 로고    scopus 로고
    • Accuracy of coding for possible warfarin complications in hospital discharge abstracts
    • 19 Arnason, T., Wells, P.S., van Walraven, C., Forster, A.J., Accuracy of coding for possible warfarin complications in hospital discharge abstracts. Thromb Res 118 (2006), 253–262.
    • (2006) Thromb Res , vol.118 , pp. 253-262
    • Arnason, T.1    Wells, P.S.2    van Walraven, C.3    Forster, A.J.4
  • 20
    • 0032940813 scopus 로고    scopus 로고
    • A relative power table for nested matched case-control studies
    • 20 Pang, D., A relative power table for nested matched case-control studies. Occup Environ Med 56 (1999), 67–69.
    • (1999) Occup Environ Med , vol.56 , pp. 67-69
    • Pang, D.1
  • 21
    • 84895546812 scopus 로고    scopus 로고
    • Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) trial analysis
    • 21 Hijazi, Z., Hohnloser, S.H., Oldgren, J., et al. Efficacy and safety of dabigatran compared with warfarin in relation to baseline renal function in patients with atrial fibrillation: a RE-LY (Randomized Evaluation of Long-term Anticoagulation Therapy) trial analysis. Circulation 129 (2014), 961–970.
    • (2014) Circulation , vol.129 , pp. 961-970
    • Hijazi, Z.1    Hohnloser, S.H.2    Oldgren, J.3
  • 22
    • 80054071757 scopus 로고    scopus 로고
    • Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment
    • 22 Fox, K.A.A., Piccini, J.P., Wojdyla, D., et al. Prevention of stroke and systemic embolism with rivaroxaban compared with warfarin in patients with non-valvular atrial fibrillation and moderate renal impairment. Eur Heart J 32 (2011), 2387–2394.
    • (2011) Eur Heart J , vol.32 , pp. 2387-2394
    • Fox, K.A.A.1    Piccini, J.P.2    Wojdyla, D.3
  • 23
    • 84895452890 scopus 로고    scopus 로고
    • Comparisons between novel oral anticoagulants and vitamin K antagonists in patients with CKD
    • 23 Harel, Z., Sholzberg, M., Shah, P.S., et al. Comparisons between novel oral anticoagulants and vitamin K antagonists in patients with CKD. J Am Soc Nephrol 25 (2014), 431–442.
    • (2014) J Am Soc Nephrol , vol.25 , pp. 431-442
    • Harel, Z.1    Sholzberg, M.2    Shah, P.S.3
  • 24
    • 84904764432 scopus 로고    scopus 로고
    • Novel oral anticoagulants in patients with renal insufficiency: a meta-analysis of randomized trials
    • 24 Sardar, P., Chatterjee, S., Herzog, E., et al. Novel oral anticoagulants in patients with renal insufficiency: a meta-analysis of randomized trials. Can J Cardiol 30 (2014), 888–897.
    • (2014) Can J Cardiol , vol.30 , pp. 888-897
    • Sardar, P.1    Chatterjee, S.2    Herzog, E.3
  • 25
    • 84937468276 scopus 로고    scopus 로고
    • One-year risk of bleeding with dabigatran in patients with atrial fibrillation: placing real-world results into perspective
    • 25 Miyares, M.A., One-year risk of bleeding with dabigatran in patients with atrial fibrillation: placing real-world results into perspective. JAMA Intern Med 175 (2015), 1242–1243.
    • (2015) JAMA Intern Med , vol.175 , pp. 1242-1243
    • Miyares, M.A.1
  • 26
    • 84875780959 scopus 로고    scopus 로고
    • Dabigatran and postmarketing reports of bleeding
    • 26 Southworth, M.R., Reichman, M.E., Unger, E.F., Dabigatran and postmarketing reports of bleeding. N Engl J Med 368 (2013), 1272–1274.
    • (2013) N Engl J Med , vol.368 , pp. 1272-1274
    • Southworth, M.R.1    Reichman, M.E.2    Unger, E.F.3
  • 27
    • 84904866522 scopus 로고    scopus 로고
    • The trouble with dabigatran
    • 27 Charlton, B., Redberg, R., The trouble with dabigatran. BMJ, 349, 2014, g4681.
    • (2014) BMJ , vol.349 , pp. g4681
    • Charlton, B.1    Redberg, R.2
  • 28
    • 84857853180 scopus 로고    scopus 로고
    • Bleeding risk with dabigatran in the frail elderly
    • 28 Harper, P., Young, L., Merriman, E., Bleeding risk with dabigatran in the frail elderly. N Engl J Med 366 (2012), 864–866.
    • (2012) N Engl J Med , vol.366 , pp. 864-866
    • Harper, P.1    Young, L.2    Merriman, E.3
  • 29
    • 84920566138 scopus 로고    scopus 로고
    • Risk of bleeding with dabigatran in atrial fibrillation
    • 29 Hernandez, I., Baik, S.H., Pinera, A., Zhang, Y., Risk of bleeding with dabigatran in atrial fibrillation. JAMA Intern Med 175 (2015), 18–24.
    • (2015) JAMA Intern Med , vol.175 , pp. 18-24
    • Hernandez, I.1    Baik, S.H.2    Pinera, A.3    Zhang, Y.4
  • 30
    • 77954326078 scopus 로고    scopus 로고
    • Incidence and outcomes of acute kidney injury in a referred chronic kidney disease cohort
    • 30 Lafrance, J.P., Djurdjev, O., Levin, A., Incidence and outcomes of acute kidney injury in a referred chronic kidney disease cohort. Nephrol Dial Transplant 25 (2010), 2203–2209.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 2203-2209
    • Lafrance, J.P.1    Djurdjev, O.2    Levin, A.3
  • 31
    • 84874251027 scopus 로고    scopus 로고
    • Acute management of bleeding in patients on novel oral anticoagulants
    • 31 Siegal, D.M., Crowther, M.A., Acute management of bleeding in patients on novel oral anticoagulants. Eur Heart J 34 (2013), 489–498b.
    • (2013) Eur Heart J , vol.34 , pp. 489-498b
    • Siegal, D.M.1    Crowther, M.A.2
  • 32
    • 45949098057 scopus 로고    scopus 로고
    • Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th edition)
    • 32 Schulman, S., Beyth, R.J., Kearon, C., Levine, M.N., Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th edition). Chest 133 (2008), 257s–298s.
    • (2008) Chest , vol.133 , pp. 257s-298s
    • Schulman, S.1    Beyth, R.J.2    Kearon, C.3    Levine, M.N.4
  • 33
    • 84937501261 scopus 로고    scopus 로고
    • Dosage of dabigatran as a risk factor for bleeding in atrial fibrillation
    • 33 Liu, S., Kim, C.O., Lucyk, S.N., Dosage of dabigatran as a risk factor for bleeding in atrial fibrillation. JAMA Intern Med 175 (2015), 1244–1245.
    • (2015) JAMA Intern Med , vol.175 , pp. 1244-1245
    • Liu, S.1    Kim, C.O.2    Lucyk, S.N.3
  • 34
    • 84907965406 scopus 로고    scopus 로고
    • 2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of Atrial Fibrillation
    • 34 Verma, A., Cairns, J.A., Mitchell, L.B., et al. 2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of Atrial Fibrillation. Can J Cardiol 30 (2014), 1114–1130.
    • (2014) Can J Cardiol , vol.30 , pp. 1114-1130
    • Verma, A.1    Cairns, J.A.2    Mitchell, L.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.