Cancer among patients with type 2 diabetes mellitus: A population-based cohort study in northeastern Italy

Cancer Epidemiology

Volumn 41, Issue , 2016, Pages 80-87

  Gini, Andrea ^a   Bidoli, Ettore ^a   Zanier, Loris ^b   Clagnan, Elena ^b   Zanette, Giorgio ^c   Gobbato, Michele ^b   De Paoli, Paolo ^a   Serraino, Diego ^a  

^a CENTRO DI RIFERIMENTO ONCOLOGICO   (Italy)

^b ARPA Regional Environmental Protection Agency Friuli Venezia Giulia   (Italy)

^c S MARIA DEGLI ANGELI HOSPITAL   (Italy)

Author keywords

Cancer; Cancer risk; Population based cohort study; Record linkage; Survival; Type 2 diabetes mellitus

Indexed keywords

ADULT; AGED; ARTICLE; CANCER DIAGNOSIS; CANCER REGISTRY; CANCER RISK; CANCER SURVIVAL; COHORT ANALYSIS; FEMALE; FEMALE GENITAL TRACT CANCER; HOSPITAL DISCHARGE; HUMAN; ITALY; LIVER CANCER; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS CANCER; POPULATION RESEARCH; PRIORITY JOURNAL; PROSTATE CANCER; RETROSPECTIVE STUDY; SMALL INTESTINE CANCER; STANDARDIZED INCIDENCE RATIO; SURVIVAL RATE; COMPLICATION; INCIDENCE; MIDDLE AGED; NEOPLASMS; PATHOLOGY; RISK FACTOR; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FEMALE; HUMANS; INCIDENCE; ITALY; MALE; MIDDLE AGED; NEOPLASMS; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 84960848779     PISSN: 18777821     EISSN: 1877783X     Source Type: Journal    
DOI: 10.1016/j.canep.2016.01.011     Document Type: Article

References (40)

1. International Diabetes Federation IDF Diabetes Atlas Update Poster 2014, International Diabetes Federation, Brussels, Belgium. 6th edn.
2. Emerging Risk Factors Collaboration, Sarwar N., Gao P., Seshasai S.R.K., Gobin R., Kaptoge S., Di Angelantonio E., Ingelsson E., Lawlor D.A., Selvin E., Stampfer M., Stehouwer C.D., Lewington S., Pennells L., Thompson A., Sattar N., White I.R., Ray K.K., Danesh J. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet 2010, 375(9733):2215-2222.
3. Liu X., Hemminki K., Försti A., Sundquist K., Sundquist J., Ji J. Cancer risk in patients with type 2 diabetes mellitus and their relatives. Int. J. Cancer 2015, 137(4):903-910.
4. Walker J.J., Brewster D.H., Colhoun H.M., Fischbacher C.M., Leese G.P., Lindsay R.S., McKnight J.A., Philip S., Sattar N., Stockton D.L., Wild S.H. Type 2 diabetes, socioeconomic status and risk of cancer in Scotland 2001-2007. Diabetologia 2013, 56(8):1712-1715.
5. Zhang P.H., Chen Z.W., Lv D., Xu Y.Y., Gu W.L., Zhang X.H., Le Y.L., Zhu H., Zhu Y.M. Increased risk of cancer in patients with type 2 diabetes mellitus: a retrospective cohort study in China. BMC Public Health 2012, 12(567). 10.1186/1471-2458-12-567.
6. Ben Q., Xu M., Ning X., Liu J., Hong S., Huang W., Zhang H., Li Z. Diabetes mellitus and risk of pancreatic cancer: a meta-analysis of cohort studies. Eur. J. Cancer 2011, 47(13):1928-1937.
7. Bosetti C., Rosato V., Li D., Silverman D., Petersen G.M., Bracci P.M., Neale R.E., Muscat J., Anderson K., Gallinger S., Olson S.H., Miller A.B., Bas Bueno-de-Mesquita H., Scelo G., Janout V., Holcatova I., Lagiou P., Serraino D., Lucenteforte E., Fabianova E., Ghadirian P., Baghurst P.A., Zatonski W., Foretova L., Fontham E., Bamlet W.R., Holly E.A., Negri E., Hassan M., Prizment A., Cotterchio M., Cleary S., Kurtz R.C., Maisonneuve P., Trichopoulos D., Polesel J., Duell E.J., Boffetta P., La Vecchia C. Diabetes, antidiabetic medications, and pancreatic cancer risk: an analysis from the International Pancreatic Cancer Case-Control Consortium. Ann. Oncol. 2014, 25(10):2065-2072.
8. Wang C., Wang X., Gong G., Ben Q., Qiu W., Chen Y., Li G., Wang L. Increased risk of hepatocellular carcinoma in patients with diabetes mellitus: a systematic review and meta-analysis of cohort studies. Int. J. Cancer 2012, 130(7):1639-1648.
9. Wu L., Yu C., Jiang H., Tang J., Huang H., Gao J., Zhang X. Diabetes mellitus and the occurrence of colorectal cancer: an updated meta-analysis of cohort studies. Diabetes Technol. Ther. 2013, 15(5):419-427.
10. Boyle P., Boniol M., Koechlin A., Robertson C., Valentini F., Coppens K., Fairley L.L., Boniol M., Zheng T., Zhang Y., Pasterk M., Smans M., Curado M.P., Mullie P., Gandini S., Bota M., Bolli G.B., Rosenstock J., Autier P. Diabetes and breast cancer risk: a meta-analysis. Br. J. Cancer 2012, 107(9):1608-1617.
11. Fang H., Yao B., Yan Y., Xu H., Liu Y., Tang H., Zhou J., Cao L., Wang W., Zhang J., Zhao L., Chen X., Zhang F., Zhao Y. Diabetes mellitus increases the risk of bladder cancer: an updated meta-analysis of observational studies. Diabetes Technol. Ther. 2013, 15(11):914-922.
12. Tsilidis K.K., Allen N.E., Appleby P.N., Rohrmann S., Nöthlings U., Arriola L., Gunter M.J., Chajes V., Rinaldi S., Romieu I., Murphy N., Riboli E., Tzoulaki I., Kaaks R., Lukanova A., Boeing H., Pischon T., Dahm C.C., Overvad K., Quirós J.R., Fonseca-Nunes A., Molina-Montes E., Gavrila Chervase D., Ardanaz E., Khaw K.T., Wareham N.J., Roswall N., Tjønneland A., Lagiou P., Trichopoulos D., Trichopoulou A., Palli D., Pala V., Tumino R., Vineis P., Bueno-de-Mesquita H.B., Malm J., Orho-Melander M., Johansson M., Stattin P., Travis R.C., Key T.J. Diabetes mellitus and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition. Int. J. Cancer 2015, 136(2):372-381.
13. Joost H.G. Diabetes and cancer: epidemiology and potential mechanisms. Diabetes Vasc. Dis. Res. 2014, 11(6):390-394.
14. Kasuga M., Ueki K., Tajima N., Noda M., Ohashi K., Noto H., Goto A., Ogawa W., Sakai R., Tsugane S., Hamajima N., Nakagama H., Tajima K., Miyazono K., Imai K. Report of the Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer. Cancer Sci. 2013, 104(7):965-976.
15. Valent F., Tillati S., Zanier L. Prevalence and comorbidities of known diabetes in northeastern Italy. J. Diabetes Invest. 2013, 4(4):355-360.
16. Valent F. Diabetes mellitus and cancer of the digestive organs: an Italian population-based cohort study. J. Diabetes Complication 2015, [Epub ahead of print]. 10.1016/j.jdiacomp.2015.07.017.
17. Birri, S., Bidoli, E., Zucchetto, A., Dal Maso, L., Zanier, L., Serraino, D., 2011. I tumori in Friuli Venezia Giulia. Dati di incidenza, sopravvivenza e prevalenza: aggiornamento al 2007. Available from:. http://www.cro.it/opencms/export/sites/cro/it/_organigramma/_docs/Tumori-1995-2007-rev.pdf.
18. Cancer Incidence in Five Continents 2013, vol. X. International Agency for Research on Cancer, Lyon, (electronic version), Available from: http://ci5.iarc.fr, (accessed 01.07.16).
19. Breslow N.E., Day N.E. Statistical methods in cancer research. The Design and Analysis of Cohort Studies 1987, vol. II. IARC Sci Publ., Lyon.
20. Ogunleye A.A., Ogston S.A., Morris A.D., Evans J.M.M. A cohort study of the risk of cancer associated with type 2 diabetes. Br. J. Cancer 2009, 101(7):1199-1201.
21. Johnson J.A., Carstensen B., Witte D., Bowker S.L., Lipscombe L., Renehan A.G., on behalf of the Diabetes and Cancer Research Consortium Diabetes and cancer (1): evaluating the temporal relationship between type 2 diabetes and cancer incidence. Diabetologia 2012, 55:1607-1618.
22. Borena W., Strohmaier S., Lukanova A., Bjørge T., Lindkvist B., Hallmans G., Edlinger M., Stocks T., Nagel G., Manjer J., Engeland A., Selmer R., Häggström C., Tretli S., Concin H., Jonsson H., Stattin P., Ulmer H. Metabolic risk factors and primary liver cancer in a prospective study of 578,700 adults. Int. J. Cancer 2012, 131(1):193-200.
23. Giovannucci E., Harlan D.M., Archer M.C., Bergenstal R.M., Gapstur S.M., Habel L.A., Pollak M., Regensteiner J.G., Yee D. Diabetes and cancer: a consensus report. Diabetes Care 2010, 33(7):1674-1685.
24. Bosetti C., Rosato V., Polesel J., Levi F., Talamini R., Montella M., Negri E., Tavani A., Zucchetto A., Franceschi S., Corrao G., La Vecchia C. Diabetes mellitus and cancer risk in a network of case-control studies. Nutr. Cancer 2012, 64(5):643-651.
25. Giovannucci E., Michaud D. The role of obesity and related metabolic disturbances in cancers of the colon, prostate, and pancreas. Gastroenterology 2007, 132(6):2208-2225.
26. La Vecchia C., Giordano S.H., Hortobagyi G.N., Chabner B. Overweight, obesity, diabetes, and risk of breast cancer: interlocking pieces of the puzzle. Oncologist 2011, 16(6):726-729.
27. Xue F., Michels K.B. Diabetes, metabolic syndrome, and breast cancer: a review of the current evidence. Am. J. Clin. Nutr. 2007, 86(3):s823-s835.
28. Franceschi S., Favero A., La Vecchia C., Barón A.E., Negri E., Dal Maso L., Giacosa A., Montella M., Conti E., Amadori D. Body size indices and breast cancer risk before and after menopause. Int. J. Cancer 1996, 67(2):181-186.
29. Friberg E., Orsini N., Mantzoros C.S., Wolk A. Diabetes mellitus and risk of endometrial cancer: a meta-analysis. Diabetologia 2007, 50(7):1365-1374.
30. Saltzman B.S., Doherty J.A., Hill D.A., Beresford S.A., Voigt L.F., Chen C., Weiss N.S. Diabetes and endometrial cancer: an evaluation of the modifying effects of other known risk factors. Am. J. Epidemiol. 2008, 167(5):607-614.
31. Augustin L.S.A., Dal Maso L., Franceschi S., Talamini R., Kendall C.W.C., Jenkins D.J.A., Vidgen E., La Vecchia C. Association between components of the insulin-like growth factor system and endometrial cancer risk. Oncology 2004, 67(1):54-59.
32. Luo J., Beresford S., Chen C., Chlebowski R., Garcia L., Kuller L., Regier M., Wactawski-Wende J., Margolis K.L. Association between diabetes, diabetes treatment and risk of developing endometrial cancer. Br. J. Cancer 2014, 111(7):1432-1439.
33. Larsson S.C., Wolk A. Diabetes mellitus and incidence of kidney cancer: a meta-analysis of cohort studies. Diabetologia 2011, 54(5):1013-1018.
34. Kasper J.S., Giovannucci E. A meta-analysis of diabetes mellitus and the risk of prostate cancer. Cancer Epidemiol. Biomark Prev. 2006, 15(11):2056-2062.
35. Harding J.L., Shaw J.E., Peeters A., Cartensen B., Magliano D.J. Cancer risk among people with type 1 and type 2 diabetes: disentangling true associations, detection bias, and reverse causation. Diabetes Care 2015, 38(2):264-270.
36. Akter S., Okazaki H., Kuwahara K., Miyamoto T., Murakami T., Shimizu C., Shimizu M., Tomita K., Nagahama S., Eguchi M., Kochi T., Imai T., Nishihara A., Sasaki N., Nakagawa T., Yamamoto S., Honda T., Uehara A., Yamamoto M., Hori A., Sakamoto N., Nishiura C., Totsuzaki T., Kato N., Fukasawa K., Pham N.M., Kurotani K., Nanri A., Kabe I., Mizoue T., Sone T., Dohi S. Smoking, smoking cessation, and the risk of type 2 diabetes among Japanese adults: Japan Epidemiology Collaboration on Occupational Health Study. PLoS One 2015, 10(7):e0132166. 10.1371/journal.pone.0132166.
37. Libby G., Donnelly L.A., Donnan P.T., Alessi D.R., Morris A.D., Evans J.M.M. New users of metformin are at low risk of incident cancer. Diabetes Care 2009, 32(9):1620-1625.
38. Romon I., Rey G., Mandereau-Bruno L., Weill A., Jougla E., Eschwège E., Simon D., Druet C., Fagot-Campagna A. The excess mortality related to cardiovascular diseases and cancer among adults pharmacologically treated for diabetes-the 2001-2006 ENTRED cohort. Diabetes Med. 2014, 31(8):946-953.
39. Tuomi T., Santoro N., Caprio S., Cai M., Weng J., Groop L. The many faces of diabetes: a disease with increasing heterogeneity. Lancet 2014, 383(9922):1084-1094.
40. Buzzetti R., Di Pietro S., Giaccari A., Petrone A., Locatelli M., Suraci C., Capizzi M., Arpi M.L., Bazzigaluppi E., Dotta F., Bosi E., for the Non Insulin Requiring Autoimmune Diabetes (NIRAD) Study Group High titer of autoantibodies to GAD identifies a specific phenotype of adult-onset autoimmune diabetes. Diabetes Care 2007, 30(4):932-938.