Nef exosomes isolated from the plasma of individuals with HIV-associated dementia (HAD) can induce Aβ1–42 secretion in SH-SY5Y neural cells

Journal of NeuroVirology

Volumn 22, Issue 2, 2016, Pages 179-190

  Khan, Mahfuz B ^a   Lang, Michelle J ^a   Huang, Ming Bo ^a   Raymond, Andrea ^b   Bond, Vincent C ^a   Shiramizu, Bruce ^c   Powell, Michael D ^a  

^a MOREHOUSE SCHOOL OF MEDICINE   (United States)

^b FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^c UNIVERSITY OF HAWAII   (United States)

Author keywords

Amyloid; Combination antiretroviral therapy; HIV; HIV associated neurocognitive disorders; Nef

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; MESSENGER RNA; NEF PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; NEF PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1; PEPTIDE FRAGMENT; VIRUS RNA;

ADULT; AGED; ARTICLE; CELL ISOLATION; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; EMBRYO; EXOSOME; FEMALE; GENE EXPRESSION; HEK293 CELL LINE; HIV ASSOCIATED DEMENTIA; HUMAN; HUMAN CELL; MALE; MIDDLE AGED; NEUROBLASTOMA CELL LINE; NEUROPATHOLOGY; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN INTERACTION; PROTEIN SECRETION; SH SY5Y CELL; TARGET CELL; UPREGULATION; AIDS DEMENTIA COMPLEX; BIOSYNTHESIS; BLOOD; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SECRETION (PROCESS); TUMOR CELL LINE; VIROLOGY; VIRUS LOAD;

ADULT; AGED; AIDS DEMENTIA COMPLEX; AMYLOID BETA-PEPTIDES; ANTI-HIV AGENTS; CELL LINE, TUMOR; EXOSOMES; FEMALE; GENE EXPRESSION REGULATION; HEK293 CELLS; HIV-1; HUMANS; MALE; MIDDLE AGED; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; NEURONS; PEPTIDE FRAGMENTS; RNA, MESSENGER; RNA, VIRAL; VIRAL LOAD;

EID: 84960805724     PISSN: 13550284     EISSN: 15382443     Source Type: Journal    
DOI: 10.1007/s13365-015-0383-6     Document Type: Article

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