Air leak after lung resection: Pathophysiology and patients' implications

Journal of Thoracic Disease

Volumn 8, Issue , 2016, Pages S46-S54

  Pompili, Cecilia ^a   Miserocchi, Giuseppe ^b  

^a ST JAMES S UNIVERSITY HOSPITAL   (United Kingdom)

^b UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

Air leak; Basic research; Chest tubes; Patients' perspectives

Indexed keywords

EXPERIMENTAL STUDY; HOSPITAL FINANCE; HUMAN; LUNG LOBECTOMY; NOMENCLATURE; PERCEPTION; PLEURA CAVITY; QUALITY OF LIFE; SCORING SYSTEM; STANDARDIZATION; TELEMONITORING; THORAX DRAINAGE;

EID: 84960491675     PISSN: 20721439     EISSN: 20776624     Source Type: Journal    
DOI: 10.3978/j.issn.2072-1439.2015.11.08     Document Type: Review

References (48)

1. Varela G, Jiménez MF, Novoa N, et al. Estimating hospital costs attributable to prolonged air leak in pulmonary lobectomy. Eur J Cardiothorac Surg 2005;27:329-33
2. Salati M, Brunelli A, Xiumè F, et al. Does fast-tracking increase the readmission rate after pulmonary resection? A case-matched study. Eur J Cardiothorac Surg 2012;41:1083-7; discussion 1087
3. Pompili C, Salati M, Refai M, et al. Recurrent air leak soon after pulmonary lobectomy: an analysis based on an electronic airflow evaluation†. Eur J Cardiothorac Surg 2015. [Epub ahead of print]
4. Varela G, Jiménez MF, Novoa NM, et al. Postoperative chest tube management: measuring air leak using an electronic device decreases variability in the clinical practice. Eur J Cardiothorac Surg 2009;35:28-31
5. Lackey A, Mitchell JD. The cost of air leak: physicians' and patients' perspectives. Thorac Surg Clin 2010;20:407-11
6. Pompili C, Tiberi M, Salati M, et al. Patient satisfaction with health-care professionals and structure is not affected by longer hospital stay and complications after lung resection: a case-matched analysis. Interact Cardiovasc Thorac Surg 2015;20:236-41
7. Southey D, Pullinger D, Loggos S, et al. Discharge of thoracic patients on portable digital suction: Is it costeffective? Asian Cardiovasc Thorac Ann 2015;23:832-8
8. Rieger KM, Wroblewski HA, Brooks JA, et al. Postoperative outpatient chest tube management: initial experience with a new portable system. Ann Thorac Surg 2007;84:630-2
9. Brunelli A, Cassivi SD, Halgren L. Risk factors for prolonged air leak after pulmonary resection. Thorac Surg Clin 2010;20:359-64
10. Brunelli A, Varela G, Refai M, et al. A scoring system to predict the risk of prolonged air leak after lobectomy. Ann Thorac Surg 2010;90:204-9
11. Orsini B, Baste JM, Gossot D, et al. Index of prolonged air leak score validation in case of video-assisted thoracoscopic surgery anatomical lung resection: results of a nationwide study based on the French national thoracic database, EPITHOR†. Eur J Cardiothorac Surg 2015;48:608-11
12. Rivera C, Bernard A, Falcoz PE, et al. Characterization and prediction of prolonged air leak after pulmonary resection: a nationwide study setting up the index of prolonged air leak. Ann Thorac Surg 2011;92:1062-8
13. Brunelli A, Beretta E, Cassivi SD, et al. Consensus definitions to promote an evidence-based approach to management of the pleural space. A collaborative proposal by ESTS, AATS, STS, and GTSC. Eur J Cardiothorac Surg 2011;40:291-7
14. Refai M, Brunelli A, Varela G, et al. The values of intrapleural pressure before the removal of chest tube in non-complicated pulmonary lobectomies. Eur J Cardiothorac Surg 2012;41:831-3
15. Wang NS. Mesothelial cells in situ. In: Chrétien J, Bignon J, Hirsh A, editors. The pleura in health and disease. New York: M. Dekker; 1985:23-42
16. Mariassy AT, Wheeldon EB. The pleura: a combined light microscopic, scanning, and transmission electron microscopic study in the sheep. I. Normal pleura. Exp Lung Res 1983;4:293-314
17. Albertine KH, Wiener-Kronish JP, Staub NC. The structure of the parietal pleura and its relationship to pleural liquid dynamics in sheep. Anat Rec 1984;208:401-9
18. Albertine KH, Wiener-Kronish JP, Roos PJ, et al. Structure, blood supply, and lymphatic vessels of the sheep's visceral pleura. Am J Anat 1982;165:277-94
19. Miserocchi G, Negrini D. Pleural space: pressures and fluid dynamics. In: Crystal RG, West JB, Weibel ER, et al, editors. The lung: scientific foundations. Vol.1. New York: Raven Press, 1997:1217-25
20. Negrini D, Del Fabbro M, Gonano C, et al. Distribution of diaphragmatic lymphatic lacunae. J Appl Physiol (1985) 1992;72:1166-72
21. Venturoli D, Grungo S, Negrini D, et al. Fractal Distribution of Serosal Lymphatics. In: Fractals in Biology and Medicine. Springer, 1998:345-53
22. Policard A, Galy P. La plèvre: mécanismes normaux et pathologiques. Paris: Masson, 1942:77-6
23. Rouvière H. Anatomie humaine, descriptive et topographique. T.2.9th ed. Paris: Masson, 1962:813-20
24. Leak LV. Gross and ultrastructural morphologic features of the diaphragm. Am Rev Respir Dis 1979;119:3-21
25. Bernaudin JF, Fleury J. Anatomy of the blood and lymphatics circulation of the pleural serosa. In: Chrétien J, Bignon J, Hirsh A, editors. The pleura in health and disease. New York: M. Dekker, 1985:101-24
26. Miserocchi G, Venturoli D, Negrini D, et al. Intrapleural fluid movements described by a porous flow model. J Appl Physiol 1992;73:2511-6
27. Miserocchi G, Nakamura T, Mariani E, et al. Pleural liquid pressure over the interlobar mediastinal and diaphragmatic surfaces of the lung. Respir Physiol 1981;46:61-9
28. Negrini D, Reed RK, Miserocchi G. Permeabiliry-surface area product and reflection coefficient of the parietal pleura in dogs. J Appl Physiol (1985) 1991;71:2543-7
29. Negrini D, Townseley MI, Taylor AE. Hydraulic conductivity and osmotic reflection coefficient of canine parietal pleura in vivo. J Appl Physiol (1985) 1990;69:438-42
30. Miserocchi G. Physiology and pathophysiology of pleural fluid turnover. Eur Respir J 1997;10:219-25
31. Miserocchi G, Venturoli D, Negrini D, et al. Model of pleural fluid turnover. J Appl Physiol (1985) 1993;75:1798-806
32. Zocchi L. Physiology and pathophysiology of pleural fluid turnover. Eur Respir J 2002;20:1545-58
33. Hills BA. Graphite-like lubrication of mesothelium by oligolamellar pleural surfactant. J Appl Physiol (1985) 1992;73:1034-9
34. Joseph J, Badrinath P, Basran GS, et al. Is the pleural fluid transudate or exudate? A revisit of the diagnostic criteria. Thorax 2001;56:867-70
35. Light RW, Macgregor MI, Luchsinger PC, et al. Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med 1972;77:507-13
36. Joseph J, Badrinath P, Basran GS, et al. Do we need all three criteria for the diagnostic separation of pleural fluid into transudates and exudates? An appraisal of the traditional criteria. Med Sci Monit 2003;9:CR474-6
37. Wiener-Kronish JP, Goldstein R, Matthay RA, et al. Lack of association of pleural effusion with chronic pulmonary arterial and right atrial hypertension. Chest 1987;92:967-70
38. Gao ZC, Xue PL, Zhang Y, et al. Potential role of human visceral pleura in pleural liquid turnover. Chin Med J (Engl) 2006;119:250-4
39. Cohen M, Sahn SA. Resolution of pleural effusions. Chest 2001;119:1547-62
40. Glazier, JB, Hughes JM, Maloney JE, et al. Vertical gradient of alveolar size in lungs of dogs frozen intact. J Appl Physiol 1967;23:694-705
41. Hoppin, FG, Green ID, Mead J. Distribution of pleural surface pressure in dogs. J Appl Physiol 1969;27:863-73
42. Hogg JC, Nepsky S. Regional lung volume and pleural pressure gradient estimated from lung density in dogs. J Appl Physiol 1969;27:198-203
43. West JB, Matthews FL. Stresses, strains, and surface pressures in the lung caused by its weight. J Appl Physiol 1972;32:332-45
44. Miserocchi G, Negrini D, Gonano C. Parenchymal stress affects interstitial and pleural pressures in in situ lung. J Appl Physiol (1985) 1991;71:1967-72
45. Shander A, Fleisher LA, Barie PS, et al. Clinical and economic burden of postoperative pulmonary complications: patient safety summit on definition, riskreducing interventions, and preventive strategies. Crit Care Med 2011;39:2163-72
46. Miserocchi G, Beretta E, Rivolta I. Respiratory mechanics and fluid dynamics after lung resection surgery. Thorac Surg Clin 2010;20:345-57
47. Salito C, Bovio D, Mazzuca E, et al. Experimental model to evaluate the effect of hydrothorax and lobar resection on lung compliance. Eur J Cardiothorac Surg 2014;45:489- 95; discussion 495
48. Bharat A, Graf N, Mullen A, et al. Pleural hypercarbia after lung surgery is associated with persistent alveolopleural fistulae. Chest 2015. [Epub ahead of print]