Safety of Live Attenuated High-Titer Varicella-Zoster Virus Vaccine in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Recipients

Biology of Blood and Marrow Transplantation

Volumn 22, Issue 4, 2016, Pages 771-775

  Aoki, Takahiro ^a   Koh, Katsuyoshi ^a   Kawano, Yutaka ^a   Mori, Makiko ^a   Arakawa, Yuki ^a   Kato, Motohiro ^a   Hanada, Ryoji ^a  

^a SAITAMA CHILDREN'S MEDICAL CENTER   (Japan)

Author keywords

Allogeneic hematopoietic stem cell transplantation; Pediatrics; Varicella zoster virus vaccine

Indexed keywords

ACICLOVIR; CYCLOSPORIN A; LIVE VACCINE; METHOTREXATE; TACROLIMUS; THYMOCYTE ANTIBODY; VARICELLA ZOSTER VACCINE; CHICKENPOX VACCINE; MYELOABLATIVE AGENT;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; CHICKENPOX; CHILD; CLINICAL ARTICLE; DRUG EFFICACY; DRUG SAFETY; GRAFT VERSUS HOST REACTION; HERPES ZOSTER; HUMAN; INFECTION PREVENTION; PEDIATRICS; VACCINATION; VIRUS STRAIN; VIRUS TITRATION; ADOLESCENT; ADVERSE EFFECTS; ALLOTRANSPLANTATION; DRUG EFFECTS; FEMALE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGY; INFANT; MALE; PATHOLOGY; PATIENT SAFETY; PRESCHOOL CHILD; PROCEDURES; RETROSPECTIVE STUDY; VARICELLA ZOSTER VIRUS; VIROLOGY; VIRUS ACTIVATION;

ADOLESCENT; CHICKENPOX VACCINE; CHILD; CHILD, PRESCHOOL; FEMALE; HEMATOLOGIC NEOPLASMS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HERPES ZOSTER; HERPESVIRUS 3, HUMAN; HUMANS; INFANT; MALE; MYELOABLATIVE AGONISTS; PATIENT SAFETY; RETROSPECTIVE STUDIES; TRANSPLANTATION, HOMOLOGOUS; VACCINATION; VACCINES, ATTENUATED; VIRUS ACTIVATION;

EID: 84960477430     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2015.12.025     Document Type: Article

References (24)

1. Koc Y., Miller K.B., Schenkein D.P., et al. Varicella zoster virus infections following allogeneic bone marrow transplantation: frequency, risk factors, and clinical outcome. Biol Blood Marrow Transplant 2000, 6:44-49.
2. Onozawa M., Hashino S., Haseyama Y., et al. Incidence and risk of postherpetic neuralgia after varicella zoster virus infection in hematopoietic cell transplantation recipients: Hokkaido Hematology Study Group. Biol Blood Marrow Transplant 2009, 15:724-729.
3. Sauerbrei A., Prager J., Hengst U., et al. Varicella vaccination in children after bone marrow transplantation. Bone Marrow Transplant 1997, 20:381-383.
4. Hata A., Asanuma H., Rinki M., et al. Use of an inactivated varicella vaccine in recipients of hematopoietic-cell transplants. N Engl J Med 2002, 347:26-34.
5. Ljungman P., Cordonnier C., Einsele H., et al. Vaccination of hematopoietic cell transplant recipients. Bone Marrow Transplant 2009, 44:521-526.
6. Tomblyn M., Chiller T., Einsele H., et al. Guidelines for preventing infectious complications among hematopoietic cell transplantation recipients: a global perspective. Biol Blood Marrow Transplant 2009, 15:1143-1238.
7. Ljungman P., Engelhard D., de la Camara R., et al. Vaccination of stem cell transplant recipients: recommendations of the Infectious Diseases Working Party of the EBMT. Bone Marrow Transplant 2005, 35:737-746.
8. Kamiya H., Asano Y., Ozaki T., et al. Varicella vaccine potency and stability during transport and delivery. Kansenshogaku Zasshi 2011, 85:161-165. [In Japanese, English abstract].
9. Ozaki T. Long-term clinical studies of varicella vaccine at a regional hospital in Japan and proposal for a varicella vaccination program. Vaccine 2013, 31:6155-6160.
10. Takahashi M., Otsuka T., Okuno Y., et al. Live vaccine used to prevent the spread of varicella in children in hospital. Lancet 1974, 304:1288-1290.
11. Takahashi M. Clinical overview of varicella vaccine: development and early studies. Pediatrics 1986, 78:736-741.
12. Chickenpox/varicella zoster and vaccine in Japan. Infectious Agents Surveillance Report 2013, 34:287-289. The National Institute of Infectious Diseases, Available at:, Accessed November 12, 2015. http://www.nih.go.jp/niid/en/iasr-vol34-e/865-iasr/4046-tpc404.html.
13. Kato K. Vaccination after stem cell transplantation. Rinsho Ketsueki 2013, 54:1926-1931. [In Japanese, English tables].
14. Kanda Y. Investigation of the freely available easy-to-use software 'EZR' for medical statistics. Bone Marrow Transplant 2013, 48:452-458.
15. Gomi Y., Imagawa T., Takahashi M., Yamanishi K. Oka varicella vaccine is distinguishable from its parental virus in DNA sequence of open reading frame 62 and its transactivation activity. J Med Virol 2000, 61:497-503.
16. Galea S.A., Sweet A., Beninger P., et al. The safety profile of varicella vaccine: a 10-year review. J Infect Dis 2008, 197:S165-S169.
17. Kussmaul S.C., Horn B.N., Dvorak C.C., et al. Safety of the live, attenuated varicella vaccine in pediatric recipients of hematopoietic SCTs. Bone Marrow Transplant 2010, 45:1602-1606.
18. Chou J.F., Kernan N.A., Prockop S., et al. Safety and immunogenicity of the live attenuated varicella vaccine following T replete or T cell-depleted related and unrelated allogeneic hematopoietic cell transplantation (alloHCT). Biol Blood Marrow Transplant 2011, 17:1708-1713.
19. Naidus E., Damon L., Schwartz B.S., et al. Experience with use of Zostavax((R)) in patients with hematologic malignancy and hematopoietic cell transplant recipients. Am J Hematol 2012, 87:123-125.
20. Issa N.C., Marty F.M., Leblebjian H., et al. Live attenuated varicella-zoster vaccine in hematopoietic stem cell transplantation recipients. Biol Blood Marrow Transplant 2014, 20:285-287.
21. Levin M.J. Immune senescence and vaccines to prevent herpes zoster in older persons. Curr Opin Immunol 2012, 24:494-500.
22. Harpaz R., Ortega-Sanchez I., Seward J. Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep 2008, 57:1-30.
23. Spoulou V., Giannaki M., Vounatsou M., et al. Long-term immunity to measles, mumps and rubella after MMR vaccination among children with bone marrow transplants. Bone Marrow Transplant 2004, 33:1187-1190.
24. Inaba H., Hartford C.M., Pei D., et al. Longitudinal analysis of antibody response to immunization in paediatric survivors after allogeneic haematopoietic stem cell transplantation. Br J Haematol 2012, 156:109-117.