Colistin-resistant Enterobacteriaceae bacteraemia: Real-life challenges and options

Clinical Microbiology and Infection

Volumn 22, Issue 2, 2016, Pages e9-e10

  Tuon, F F ^a,b   Santos, T A ^a   Almeida, R ^a   Rocha, J L ^b   Cieslinsk, J ^c   Becker, G N ^c   Arend, L N ^b,d  

^a PONTIFICAL CATHOLIC UNIVERSITY OF PARANÁ   (Brazil)

^b HOSPITAL UNIVERSITÁRIO EVANGÉLICO DE CURITIBA   (Brazil)

^c Division of Microbiology   (Brazil)

^d Laboratório Central do Estado LACEN PR   (Brazil)

Author keywords

Carbapenems; Klebsiella pneumoniae; Klebsiella pneumoniae carbapenemases; Meropenem; Polymyxin; Sepsis; Tigecycline

Indexed keywords

ANTIINFECTIVE AGENT; COLISTIN;

ADULT; AGED; ANTIBIOTIC RESISTANCE; BACTEREMIA; CLASSIFICATION; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; FEMALE; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MALE; MICROBIOLOGY; MIDDLE AGED; MORTALITY; PRACTICE GUIDELINE; TERTIARY CARE CENTER;

ADULT; AGED; ANTI-BACTERIAL AGENTS; BACTEREMIA; COLISTIN; DRUG RESISTANCE, BACTERIAL; ENTEROBACTERIACEAE; ENTEROBACTERIACEAE INFECTIONS; FEMALE; HUMANS; MALE; MIDDLE AGED; PRACTICE GUIDELINES AS TOPIC; TERTIARY CARE CENTERS;

EID: 84960476818     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2015.10.005     Document Type: Letter

References (5)

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2. Jayol A., Poirel L., Brink A., Villegas M.V., Yilmaz M., Nordmann P. Resistance to colistin associated with a single amino acid change in protein PMRB among Klebsiella pneumoniae isolates of worldwide origin. Antimicrob Agents Chemother 2014, 58:4762-4766.
3. Capone A., Giannella M., Fortini D., Giordano A., Meledandri M., Ballardini M., et al. High rate of colistin resistance among patients with carbapenem-resistant Klebsiella pneumoniae infection accounts for an excess of mortality. Clin Microbiol Infect 2013, 19:E23-E30. SEERBIO-GRAB Network.
4. Toledo P.V., Aranha Junior A.A., Arend L.N., Ribeiro V., Zavascki A.P., Tuon F.F. Activity of antimicrobial combinations against KPC-2-producing Klebsiella pneumoniae in a rat model and time-kill assay. Antimicrob Agents Chemother 2015, 59:4301-4304.
5. Gonzalez-Padilla M., Torre-Cisneros J., Rivera-Espinar F., Pontes-Moreno A., López-Cerero L., Pascual A., et al. Gentamicin therapy for sepsis due to carbapenem-resistant and colistin-resistant Klebsiella pneumoniae. J Antimicrob Chemother 2015, 70:905-913.