Long-term financing needs for HIV control in sub-Saharan Africa in 2015-2050: A modelling study

BMJ Open

Volumn 6, Issue 3, 2016, Pages

  Atun, Rifat ^a   Chang, Angela Y ^a   Ogbuoji, Osondu ^a   Silva, Sachin ^a   Resch, Stephen ^a   Hontelez, Jan ^a   Bärnighausen, Till ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFRICA; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; FINANCIAL MANAGEMENT; FUNDING; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; MODEL; PREVENTION; SCALE UP; ADOLESCENT; ADULT; AFRICA SOUTH OF THE SAHARA; DEVELOPING COUNTRY; ECONOMICS; FEMALE; HEALTH CARE COST; HEALTH SERVICE; HIV INFECTIONS; INTERNATIONAL COOPERATION; MALE; MIDDLE AGED; STATISTICS AND NUMERICAL DATA; THEORETICAL MODEL; YOUNG ADULT;

ADOLESCENT; ADULT; AFRICA SOUTH OF THE SAHARA; CD4 LYMPHOCYTE COUNT; DEVELOPING COUNTRIES; FEMALE; FINANCIAL SUPPORT; FINANCING, GOVERNMENT; HEALTH CARE COSTS; HEALTH SERVICES NEEDS AND DEMAND; HIV INFECTIONS; HUMANS; INTERNATIONAL COOPERATION; MALE; MIDDLE AGED; MODELS, THEORETICAL; YOUNG ADULT;

EID: 84960422787     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2015-009656     Document Type: Article

References (46)

1. Lozano R, Wang H, Foreman KJ, et al. Progress towards Millennium Development Goals 4 and 5 on maternal and child mortality: an updated systematic analysis. Lancet 2011;378:1139-65.
2. Murray CJL, Ortblad KF, Guinovart C, et al. Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2014;384:1005-70.
3. Coker RJ, Atun RA, McKee M. Health-care system frailties and public health control of communicable disease on the European Union's new eastern border. Lancet 2004;363:1389-92.
4. Coker R, Atun RA, McKee M. Health systems and communicable disease control. McGraw Hill, Open University Press, 2008.
5. IOM (Institute of Medicine). Investing in global health systems: sustaining gains, transforming lives. Washington DC: The National Academies Press, 2014.
6. UNAIDS. Fact Sheet 2015. Joint United Nations Programme on HIV/AIDS (UNAIDS). Geneva: UNAIDS. 2015 (accessed 16 Jan 2016).
7. UNAIDS. Epi slides. July 2014. http://www.unaids.org/en/media/unaids/contentassets/documents/document/2014/2014gapreport slides/01-Epi-slides-2014July.pdf (accessed 2 Nov. 2014).
8. United Nations General Assembly Sixty-fifth session. A/65/L.77. Political Declaration on HIV/AIDS: Intensifying our Efforts to Eliminate HIV/AIDS. http://daccess-dds-ny.un.org/doc/UNDOC/LTD/N11/367/84/PDF/N1136784.pdf?OpenElement (accessed 2 Nov. 2014).
9. Resch S, Korenromp E, Stover J, et al. Economic returns to investment in AIDS treatment in low and middle income countries. PLoS ONE 2011;6:e25310.
10. Bor J, Herbst AJ, Newell ML, et al. Increases in adult life expectancy in rural South Africa: valuing the scale-up of HIV treatment. Science 2013;339:961-5.
11. Bor J, Tanser F, Newell M-L, et al. In a study of a population cohort in South Africa, HIV patients on antiretrovirals had nearly full recovery of employment. Health Aff (Millwood) 2012;31:1459-69.
12. Eaton JW, Menzies NA, Stover J, et al. Health benefits, costs, and cost-effectiveness of earlier eligibility for adult antiretroviral therapy and expanded treatment coverage: a combined analysis of 12 mathematical models. Lancet Glob Health 2014;2:e23-34.
13. Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011;365:493-505.
14. Tanser F, Bärnighausen T, Grapsa E, et al. High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa. Science 2013;339:966-71.
15. Samb B, Evans T, Dybul M, et al. An assessment of interactions between global health initiatives and country health systems. Lancet 2009;373:2137-69.
16. Rasschaert F, Pirard M, Philips MP, et al. Positive spill-over effects of ART scale up on wider health systems development: evidence from Ethiopia and Malawi. J Int AIDS Soc 2011;14(Suppl 1):S3.
17. Wilson N. Child mortality risk and fertility: evidence from prevention of mother-to-child transmission of HIV. J Dev Econ 2015;116:74-88.
18. Grépin, KA. Leveraging HIV programs to deliver an integrated package of health services: some words of caution. J Acquir Immune Defic Syndr 2011;57:S77-9.
19. Goldberg AB, Fox A, Gore R, et al. Indicators of political commitment to respond to HIV. Sex Transm Infect 2011;88:79-84.
20. Haacker M. HIV/AIDS as a fiscal liability. Proceedings of the German Development Economics Conference; Berlin, 2011, No. 35.
21. Futures Institute. Spectrum. http://www.futuresinstitute.org/spectrum.aspx (accessed 2 Nov. 2014).
22. Hontelez JA, Lurie MN, Bärnighausen T, et al. Elimination of HIV in South Africa through expanded access to antiretroviral therapy: a model comparison study. PLoS Med 2013;10:e1001534.
23. Bärnighausen T, Bloom DE, Humair S. Economics of antiretroviral treatment vs. circumcision for HIV prevention. Proc Natl Acad Sci USA 2012;109:21271-6.
24. Futures Institute. Goals Manual-a model for estimating the effects of interventions and resource allocation on HIV infections and deaths. 2011. http://www.avenirhealth.org/Download/Spectrum/Manuals/Goals-Manual-August-2011.pdf (accessed 23 Feb. 2016).
25. Renaud-Théry F, Avila-Figueroa C, Stover J, et al. Utilization patterns and projected demand of antiretroviral drugs in low- and middle-income countries. AIDS Res Treat 2011;2011:749041.
26. Schwartländer B, Stover J, Hallett T, et al. Towards an improved investment approach for an effective response to HIV/AIDS. Lancet 2011;377:2031-41.
27. Tagar E, Sundaram M, Condliffe K, et al. Multi-Country Analysis of Treatment Costs for HIV/AIDS (MATCH): facility-level ART unit cost analysis in Ethiopia, Malawi, Rwanda, South Africa and Zambia. PLoS ONE 2014;9:e108304.
28. Menzies NA, Berruti AA, Berzon R, et al. The cost of providing comprehensive HIV treatment in PEPFAR-supported programs. AIDS 2011;25:1753.
29. United States Department of Labor. Bureau of Labor Statistics. Consumer Price Indexes. http://www.bls.gov/cpi/(accessed 10 Mar. 2014).
30. International Monetary Fund. World Economic Outlook (WEO) Database. https://www.imf.org/external/pubs/ft/weo/2015/02/weodata/index.aspx (accessed 16 Jan 2016).
31. World Health Organization. Making choices in health: WHO guide to cost-effectiveness analysis/edited by T. Tan-Torres Edejer et al. Geneva: World Health Organization, 2003. http://www.who.int/choice/publications/p-2003-generalised-cea.pdf (accessed 10 Nov. 2014).
32. Behrman JR, Kohler H-P. Assessment paper. Prevention of sexual infection. Copenhagen, Denmark and Lausanne, Switzerland: Copenhagen Consensus Center and Rush Foundation, 2011. http://www.copenhagenconsensus.com/sites/default/files/behrman-kohler.pdf (accessed 10 Nov. 2014).
33. Resch S, Ryckman T, Hecht R. Funding AIDS programmes in the era of shared responsibility: an analysis of domestic spending in 12 low-income and middle-income countries. Lancet Glob Health 2015;3:e52-61.
34. Brock DW, Wikler D. Ethical challenges in long-term funding for HIV/AIDS. Health Aff (Millwood) 2009;28:1666-76.
35. Atun R, Bataringaya J. Building a durable response to HIV/AIDS: implications for health systems. J Acquir Immune Defic Syndr 2011;57(Suppl 2):S91-5.
36. Atun R, Jaffar S, Nishtar S, et al. Improving responsiveness of health systems to non-communicable diseases. Lancet 2013;381:690-7.
37. Vassall A, Remme M, Watts C, et al. Financing essential HIV services: a new economic agenda. PLoS Med 2013;10:e1001567.
38. Lule E, Haacker M. The fiscal dimension of HIV/AIDS in Botswana, South Africa, Swaziland, and Uganda. Washington DC: World Bank, 2012. http://reliefweb.int/sites/reliefweb.int/files/resources/Full-Report-2938.pdf (accessed 20 Apr. 2015).
39. Institute for Health Metrics and Evaluation. Financing Global Health 2013: Transition in an Age of Austerity. http://www.healthdata.org/policy-report/financing-global-health-2013-transition-age-austerity (accessed 2 Nov. 2014).
40. Atun R, Knaul FM, Akachi Y, et al. Innovative financing for health: what is truly innovative? Lancet 2012;380:2044-9.
41. UNITAID. Annual reports. http://www.unitaid.eu/en/resources/publications/annual-reports (accessed 1 Nov. 2014).
42. The Charity Commission of England and Wales. Find Charities. Children's Investment Fund Foundation (CIFF). View Accounts. http://www.charitycommission. gov. uk/find-charities/(accessed 1 Nov. 2014).
43. International Finance Facility for Immunization. IFFIm Supporting GAVI. About IFFIm. Overview. http://www.iffim.org/about/overview/(accessed 1 Nov. 2014).
44. Schwalbe N, El-Ziq I. GAVI's advance market commitment. Lancet 2010;375:638-9.
45. Grigoli F, Kapsoli J. Waste not, want not: the efficiency of health expenditure in emerging and developing economies. IMF Working Paper. Washington DC: International Monetary Fund, 2013. http://www.imf.org/external/pubs/ft/wp/2013/wp13187.pdf (accessed 2 Nov. 2014).
46. Atun R, Gurol-Urganci I, McKee M. Health systems and increased longevity in people with HIV and AIDS. BMJ 2009;338:b2165.