Transfusion of 35-day stored RBCs in the presence of endotoxemia does not result in lung injury in humans

Critical Care Medicine

Volumn 44, Issue 6, 2016, Pages e412-e419

  Peters, Anna L ^a   Van Hezel, Maike E ^a,b   Cortjens, Bart ^a   Tuip De Boer, Anita M ^a   Van Bruggen, Robin ^b   De Korte, Dirk ^b   Jonkers, René E ^a   Bonta, Peter I ^a   Zeerleder, Sacha S ^a,c   Lutter, Rene ^a   Juffermans, Nicole P ^a   Vlaar, Alexander P J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b CENTRAL LABORATORY   (Netherlands)

^c SANQUIN RESEARCH   (Netherlands)

Author keywords

human; storage; transfusion; transfusion related acute lung injury; two hit model

Indexed keywords

CARBON MONOXIDE; LIPOPOLYSACCHARIDE; SODIUM CHLORIDE; OXYGEN; PROTEIN;

ADULT; ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; ENDOTOXEMIA; ERYTHROCYTE TRANSFUSION; HUMAN; HUMAN EXPERIMENT; LUNG DIFFUSION CAPACITY; LUNG HEMODYNAMICS; LUNG LAVAGE; NEUTROPHIL; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SEPSIS; SPIROMETRY; THORAX RADIOGRAPHY; TRANSFUSION RELATED ACUTE LUNG INJURY; ACUTE LUNG INJURY; ADVERSE EFFECTS; BLOOD STORAGE; BRONCHOALVEOLAR LAVAGE FLUID; CHEMICALLY INDUCED; CHEMISTRY; CYTOLOGY; DIAGNOSTIC IMAGING; ERYTHROCYTE; MALE; PARTIAL PRESSURE; PATHOPHYSIOLOGY; STANDARDS; YOUNG ADULT;

ACUTE LUNG INJURY; ADULT; BLOOD PRESERVATION; BRONCHOALVEOLAR LAVAGE FLUID; CARBON MONOXIDE; ENDOTOXEMIA; ERYTHROCYTE TRANSFUSION; ERYTHROCYTES; HEALTHY VOLUNTEERS; HUMANS; LIPOPOLYSACCHARIDES; MALE; NEUTROPHILS; OXYGEN; PARTIAL PRESSURE; PROTEINS; PULMONARY DIFFUSING CAPACITY; RADIOGRAPHY, THORACIC; SPIROMETRY; YOUNG ADULT;

EID: 84960363080     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000001614     Document Type: Article

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