-
1
-
-
0029591306
-
Differentiation of filoviruses by electron microscopy
-
Geisbert TW, Jahrling PB. 1995. Differentiation of filoviruses by electron microscopy. Virus Res 39:129–150. http://dx.doi.org/10.1016/0168-1702(95)00080-1.
-
(1995)
Virus Res
, vol.39
, pp. 129-150
-
-
Geisbert, T.W.1
Jahrling, P.B.2
-
2
-
-
0036670360
-
The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein
-
Huang Y, Xu L, Sun Y, Nabel GJ. 2002. The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein. Mol Cell 10:307–316. http://dx.doi.org/10.1016/S1097-2765(02)00588-9.
-
(2002)
Mol Cell
, vol.10
, pp. 307-316
-
-
Huang, Y.1
Xu, L.2
Sun, Y.3
Nabel, G.J.4
-
3
-
-
33645780849
-
Functional mapping of the nucleoprotein of Ebola virus
-
Watanabe S, Noda T, Kawaoka Y. 2006. Functional mapping of the nucleoprotein of Ebola virus. J Virol 80:3743–3751. http://dx.doi.org/10.1128/JVI.80.8.3743-3751.2006.
-
(2006)
J Virol
, vol.80
, pp. 3743-3751
-
-
Watanabe, S.1
Noda, T.2
Kawaoka, Y.3
-
4
-
-
84886999873
-
How do filovirus filaments bend without breaking?
-
Booth TF, Rabb MJ, Beniac DR. 2013. How do filovirus filaments bend without breaking? Trends Microbiol 21:583–593. http://dx.doi.org/10.1016/j.tim.2013.08.001.
-
(2013)
Trends Microbiol
, vol.21
, pp. 583-593
-
-
Booth, T.F.1
Rabb, M.J.2
Beniac, D.R.3
-
5
-
-
0031878483
-
Biochemical analysis of the secreted and virion glycoproteins of Ebola virus
-
Sanchez A, Yang ZY, Xu L, Nabel GJ, Crews T, Peters CJ. 1998. Biochemical analysis of the secreted and virion glycoproteins of Ebola virus. J Virol 72:6442–6447.
-
(1998)
J Virol
, vol.72
, pp. 6442-6447
-
-
Sanchez, A.1
Yang, Z.Y.2
Xu, L.3
Nabel, G.J.4
Crews, T.5
Peters, C.J.6
-
6
-
-
0030591276
-
Similar structural models of the transmembrane proteins of Ebola and avian sarcoma viruses
-
GallaherWR
-
GallaherWR. 1996. Similar structural models of the transmembrane proteins of Ebola and avian sarcoma viruses. Cell 85:477–478. http://dx.doi.org/10.1016/S0092-8674(00)81248-9.
-
(1996)
Cell
, vol.85
, pp. 477-478
-
-
-
7
-
-
47049107589
-
Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor
-
Lee JE, Fusco ML, Hessell AJ, Oswald WB, Burton DR, Saphire EO. 2008. Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor. Nature 454:177–182. http://dx.doi.org/10.1038/nature07082.
-
(2008)
Nature
, vol.454
, pp. 177-182
-
-
Lee, J.E.1
Fusco, M.L.2
Hessell, A.J.3
Oswald, W.B.4
Burton, D.R.5
Saphire, E.O.6
-
8
-
-
0032568634
-
The central feature of the membrane fusion subunit from the Ebola virus glycoprotein is a long triple-stranded coiled coil
-
Weissenhorn W, Calder LJ, Wharton SA, Skehel JJ, Wiley DC. 1998. The central feature of the membrane fusion subunit from the Ebola virus glycoprotein is a long triple-stranded coiled coil. Proc Natl Acad Sci U S A 95:6032–6036. http://dx.doi.org/10.1073/pnas.95.11.6032.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6032-6036
-
-
Weissenhorn, W.1
Calder, L.J.2
Wharton, S.A.3
Skehel, J.J.4
Wiley, D.C.5
-
9
-
-
0033020204
-
Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-Å resolution
-
Malashkevich VN, Schneider BJ, McNally ML, Milhollen MA, Pang JX, Kim PS. 1999. Core structure of the envelope glycoprotein GP2 from Ebola virus at 1.9-Å resolution. Proc Natl Acad Sci U S A 96:2662–2667. http://dx.doi.org/10.1073/pnas.96.6.2662.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 2662-2667
-
-
Malashkevich, V.N.1
Schneider, B.J.2
McNally, M.L.3
Milhollen, M.A.4
Pang, J.X.5
Kim, P.S.6
-
10
-
-
45849108331
-
Structures and mechanisms of viral membrane fusion proteins: Multiple variations on a common theme
-
White JM, Delos SE, Brecher M, Schornberg K. 2008. Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme. Crit Rev Biochem Mol Biol 43:189–219. http://dx.doi.org/10.1080/10409230802058320.
-
(2008)
Crit Rev Biochem Mol Biol
, vol.43
, pp. 189-219
-
-
White, J.M.1
Delos, S.E.2
Brecher, M.3
Schornberg, K.4
-
11
-
-
0036278649
-
C-type lectins dc-sign and l-sign mediate cellular entry by Ebola virus in cis and in trans
-
Alvarez CP, Lasala F, Carrillo J, Muñiz O, Corbí AL, Delgado R. 2002. C-type lectins dc-sign and l-sign mediate cellular entry by Ebola virus in cis and in trans. J Virol 76:6841–6844. http://dx.doi.org/10.1128/JVI.76.13.6841-6844.2002.
-
(2002)
J Virol
, vol.76
, pp. 6841-6844
-
-
Alvarez, C.P.1
Lasala, F.2
Carrillo, J.3
Muñiz, O.4
Corbí, A.L.5
Delgado, R.6
-
12
-
-
0037227457
-
Dc-sign and dc-signr bind Ebola glycoproteins and enhance infection of macrophages and endothelial cells
-
Simmons G, Reeves JD, Grogan CC, Vandenberghe LH, Baribaud F, Whitbeck JC, Burke E, Buchmeier MJ, Soilleux EJ, Riley JL, Doms RW, Bates P, Pöhlmann S. 2003. Dc-sign and dc-signr bind Ebola glycoproteins and enhance infection of macrophages and endothelial cells. Virology 305:115–123. http://dx.doi.org/10.1006/viro.2002.1730.
-
(2003)
Virology
, vol.305
, pp. 115-123
-
-
Simmons, G.1
Reeves, J.D.2
Grogan, C.C.3
Vandenberghe, L.H.4
Baribaud, F.5
Whitbeck, J.C.6
Burke, E.7
Buchmeier, M.J.8
Soilleux, E.J.9
Riley, J.L.10
Doms, R.W.11
Bates, P.12
Pöhlmann, S.13
-
13
-
-
78649710743
-
C-type lectins do not act as functional receptors for filovirus entry into cells
-
Matsuno K, Nakayama E, Noyori O, Marzi A, Ebihara H, Irimura T, Feldmann H, Takada A. 2010. C-type lectins do not act as functional receptors for filovirus entry into cells. Biochem Biophys Res Commun 403:144–148. http://dx.doi.org/10.1016/j.bbrc.2010.10.136.
-
(2010)
Biochem Biophys Res Commun
, vol.403
, pp. 144-148
-
-
Matsuno, K.1
Nakayama, E.2
Noyori, O.3
Marzi, A.4
Ebihara, H.5
Irimura, T.6
Feldmann, H.7
Takada, A.8
-
14
-
-
33749464038
-
Tyro3 family-mediated cell entry of Ebola and Marburg viruses
-
Shimojima M, Takada A, Ebihara H, Neumann G, Fujioka K, Irimura T, Jones S, Feldmann H, Kawaoka Y. 2006. Tyro3 family-mediated cell entry of Ebola and Marburg viruses. J Virol 80:10109–10116. http://dx.doi.org/10.1128/JVI.01157-06.
-
(2006)
J Virol
, vol.80
, pp. 10109-10116
-
-
Shimojima, M.1
Takada, A.2
Ebihara, H.3
Neumann, G.4
Fujioka, K.5
Irimura, T.6
Jones, S.7
Feldmann, H.8
Kawaoka, Y.9
-
15
-
-
79957780148
-
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus
-
Kondratowicz AS, Lennemann NJ, Sinn PL, Davey RA, Hunt CL, Moller-Tank S, Meyerholz DK, Rennert P, Mullins RF, Brindley M, Sandersfeld LM, Quinn K, Weller M, McCray PB, Jr, Chiorini J, Maury W. 2011. T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus. Proc Natl Acad Sci U S A 108:8426–8431. http://dx.doi.org/10.1073/pnas.1019030108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 8426-8431
-
-
Kondratowicz, A.S.1
Lennemann, N.J.2
Sinn, P.L.3
Davey, R.A.4
Hunt, C.L.5
Moller-Tank, S.6
Meyerholz, D.K.7
Rennert, P.8
Mullins, R.F.9
Brindley, M.10
Sandersfeld, L.M.11
Quinn, K.12
Weller, M.13
McCray, P.B.14
Chiorini, J.15
Maury, W.16
-
16
-
-
78149301316
-
Cellular entry of Ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes
-
Saeed MF, Kolokoltsov AA, Albrecht T, Davey RA. 2010. Cellular entry of Ebola virus involves uptake by a macropinocytosis-like mechanism and subsequent trafficking through early and late endosomes. PLoS Pathog 6:e1001110. http://dx.doi.org/10.1371/journal.ppat.1001110.
-
(2010)
Plos Pathog
, vol.6
-
-
Saeed, M.F.1
Kolokoltsov, A.A.2
Albrecht, T.3
Davey, R.A.4
-
17
-
-
78149355646
-
Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner
-
Nanbo A, Imai M, Watanabe S, Noda T, Takahashi K, Neumann G, Halfmann P, Kawaoka Y. 2010. Ebolavirus is internalized into host cells via macropinocytosis in a viral glycoprotein-dependent manner. PLoS Pathog 6:e1001121. http://dx.doi.org/10.1371/journal.ppat.1001121.
-
(2010)
Plos Pathog
, vol.6
-
-
Nanbo, A.1
Imai, M.2
Watanabe, S.3
Noda, T.4
Takahashi, K.5
Neumann, G.6
Halfmann, P.7
Kawaoka, Y.8
-
18
-
-
80052942161
-
The Ebola virus glycoprotein mediates entry via a non-classical dynamindependent macropinocytic pathway
-
Mulherkar N, Raaben M, de la Torre JC, Whelan SP, Chandran K. 2011. The Ebola virus glycoprotein mediates entry via a non-classical dynamindependent macropinocytic pathway. Virology 419:72–82. http://dx.doi.org/10.1016/j.virol.2011.08.009.
-
(2011)
Virology
, vol.419
, pp. 72-82
-
-
Mulherkar, N.1
Raaben, M.2
De La Torre, J.C.3
Whelan, S.P.4
Chandran, K.5
-
19
-
-
19144365133
-
Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection
-
Chandran K, Sullivan NJ, Felbor U, Whelan SP, Cunningham JM. 2005. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science 308:1643–1645. http://dx.doi.org/10.1126/science.1110656.
-
(2005)
Science
, vol.308
, pp. 1643-1645
-
-
Chandran, K.1
Sullivan, N.J.2
Felbor, U.3
Whelan, S.P.4
Cunningham, J.M.5
-
20
-
-
80052851832
-
Ebola virus entry requires the cholesterol transporter Niemann-pick C1
-
Carette JE, Raaben M, Wong AC, Herbert AS, Obernosterer G, Mulherkar N, Kuehne AI, Kranzusch PJ, Griffin AM, Ruthel G, Dal Cin P, Dye JM, Whelan SP, Chandran K, Brummelkamp TR. 2011. Ebola virus entry requires the cholesterol transporter Niemann-pick C1. Nature 477: 340–343. http://dx.doi.org/10.1038/nature10348.
-
(2011)
Nature
, vol.477
, pp. 340-343
-
-
Carette, J.E.1
Raaben, M.2
Wong, A.C.3
Herbert, A.S.4
Obernosterer, G.5
Mulherkar, N.6
Kuehne, A.I.7
Kranzusch, P.J.8
Griffin, A.M.9
Ruthel, G.10
Dal Cin, P.11
Dye, J.M.12
Whelan, S.P.13
Chandran, K.14
Brummelkamp, T.R.15
-
21
-
-
80052868218
-
Small molecule inhibitors reveal Niemann-pick C1 is essential for Ebola virus infection
-
Côté M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J. 2011. Small molecule inhibitors reveal Niemann-pick C1 is essential for Ebola virus infection. Nature 477: 344–348. http://dx.doi.org/10.1038/nature10380.
-
(2011)
Nature
, vol.477
, pp. 344-348
-
-
Côté, M.1
Misasi, J.2
Ren, T.3
Bruchez, A.4
Lee, K.5
Filone, C.M.6
Hensley, L.7
Li, Q.8
Ory, D.9
Chandran, K.10
Cunningham, J.11
-
22
-
-
84859907529
-
Ebola virus entry requires the host-programmed recognition of an intra-cellular receptor
-
Miller EH, Obernosterer G, Raaben M, Herbert AS, Deffieu MS, Krishnan A, Ndungo E, Sandesara RG, Carette JE, Kuehne AI, Ruthel G, Pfeffer SR, Dye JM, Whelan SP, Brummelkamp TR, Chandran K. 2012. Ebola virus entry requires the host-programmed recognition of an intra-cellular receptor. EMBO J 31:1947–1960. http://dx.doi.org/10.1038/emboj.2012.53.
-
(2012)
EMBO J
, vol.31
, pp. 1947-1960
-
-
Miller, E.H.1
Obernosterer, G.2
Raaben, M.3
Herbert, A.S.4
Deffieu, M.S.5
Krishnan, A.6
Ndungo, E.7
Sandesara, R.G.8
Carette, J.E.9
Kuehne, A.I.10
Ruthel, G.11
Pfeffer, S.R.12
Dye, J.M.13
Whelan, S.P.14
Brummelkamp, T.R.15
Chandran, K.16
-
23
-
-
82555169314
-
Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusion
-
Bale S, Liu T, Li S, Wang Y, Abelson D, Fusco M, Woods VL, Jr., Saphire EO. 2011. Ebola virus glycoprotein needs an additional trigger, beyond proteolytic priming for membrane fusion. PLoS Negl Trop Dis 5:e1395. http://dx.doi.org/10.1371/journal.pntd.0001395.
-
(2011)
Plos Negl Trop Dis
, vol.5
-
-
Bale, S.1
Liu, T.2
Li, S.3
Wang, Y.4
Abelson, D.5
Fusco, M.6
Woods, V.L.7
Saphire, E.O.8
-
24
-
-
84874138355
-
Multiple cationic amphiphiles induce a Niemann-pick C phenotype and inhibit Ebola virus entry and infection
-
Shoemaker CJ, Schornberg KL, Delos SE, Scully C, Pajouhesh H, Olinger GG, Johansen LM, White JM. 2013. Multiple cationic amphiphiles induce a Niemann-pick C phenotype and inhibit Ebola virus entry and infection. PLoS One 8:e56265. http://dx.doi.org/10.1371/journal.pone.0056265.
-
(2013)
Plos One
, vol.8
-
-
Shoemaker, C.J.1
Schornberg, K.L.2
Delos, S.E.3
Scully, C.4
Pajouhesh, H.5
Olinger, G.G.6
Johansen, L.M.7
White, J.M.8
-
25
-
-
0031449064
-
A system for functional analysis of Ebola virus glycoprotein
-
Takada A, Robison C, Goto H, Sanchez A, Murti KG, Whitt MA, Kawaoka Y. 1997. A system for functional analysis of Ebola virus glycoprotein. Proc Natl Acad Sci U S A 94:14764–14769. http://dx.doi.org/10.1073/pnas.94.26.14764.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 14764-14769
-
-
Takada, A.1
Robison, C.2
Goto, H.3
Sanchez, A.4
Murti, K.G.5
Whitt, M.A.6
Kawaoka, Y.7
-
26
-
-
84940856868
-
Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion
-
Kleinfelter LM, Jangra RK, Jae LT, Herbert AS, Mittler E, Stiles KM, Wirchnianski AS, Kielian M, Brummelkamp TR, Dye JM, Chandran K. 2015. Haploid genetic screen reveals a profound and direct dependence on cholesterol for hantavirus membrane fusion. mBio 6:e00801-15. http://dx.doi.org/10.1128/mBio.00801-15.
-
(2015)
Mbio
, vol.6
-
-
Kleinfelter, L.M.1
Jangra, R.K.2
Jae, L.T.3
Herbert, A.S.4
Mittler, E.5
Stiles, K.M.6
Wirchnianski, A.S.7
Kielian, M.8
Brummelkamp, T.R.9
Dye, J.M.10
Chandran, K.11
-
27
-
-
84877578867
-
A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum
-
Shaner NC, Lambert GG, Chammas A, Ni Y, Cranfill PJ, Baird MA, Sell BR, Allen JR, Day RN, Israelsson M, Davidson MW, Wang J. 2013. A bright monomeric green fluorescent protein derived from Branchiostoma lanceolatum. Nat Methods 10:407–409. http://dx.doi.org/10.1038/nmeth.2413.
-
(2013)
Nat Methods
, vol.10
, pp. 407-409
-
-
Shaner, N.C.1
Lambert, G.G.2
Chammas, A.3
Ni, Y.4
Cranfill, P.J.5
Baird, M.A.6
Sell, B.R.7
Allen, J.R.8
Day, R.N.9
Israelsson, M.10
Davidson, M.W.11
Wang, J.12
-
28
-
-
0029118831
-
Efficient recovery of infectious vesicular virus entirely from cDNA clones
-
Whelan SP, Ball LA, Barr JN, Wertz GT. 1995. Efficient recovery of infectious vesicular virus entirely from cDNA clones. Proc Natl Acad SciU S A 92:8388–8392. http://dx.doi.org/10.1073/pnas.92.18.8388.
-
(1995)
Proc Natl Acad Sciu S A
, vol.92
, pp. 8388-8392
-
-
Whelan, S.P.1
Ball, L.A.2
Barr, J.N.3
Wertz, G.T.4
-
29
-
-
0036893140
-
Covalent modifications of the Ebola virus glycoprotein
-
Jeffers SA, Sanders DA, Sanchez A. 2002. Covalent modifications of the Ebola virus glycoprotein. J Virol 76:12463–12472. http://dx.doi.org/10.1128/JVI.76.24.12463-12472.2002.
-
(2002)
J Virol
, vol.76
, pp. 12463-12472
-
-
Jeffers, S.A.1
Sanders, D.A.2
Sanchez, A.3
-
30
-
-
37049006295
-
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity
-
Kaletsky RL, Simmons G, Bates P. 2007. Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity. J Virol 81: 13378–13384. http://dx.doi.org/10.1128/JVI.01170-07.
-
(2007)
J Virol
, vol.81
, pp. 13378-13384
-
-
Kaletsky, R.L.1
Simmons, G.2
Bates, P.3
-
31
-
-
0023642631
-
Fusion of influenza virus in an intracellular acidic compartment measured by fluorescence dequenching
-
Stegmann T, Morselt HW, Scholma J, Wilschut J. 1987. Fusion of influenza virus in an intracellular acidic compartment measured by fluorescence dequenching. Biochim Biophys Acta 904:165–170. http://dx.doi.org/10.1016/0005-2736(87)90100-3.
-
(1987)
Biochim Biophys Acta
, vol.904
, pp. 165-170
-
-
Stegmann, T.1
Morselt, H.W.2
Scholma, J.3
Wilschut, J.4
-
33
-
-
0037690744
-
Differential requirements of Rab5 and Rab7 for endocytosis of influenza and other enveloped viruses
-
Sieczkarski SB, Whittaker GR. 2003. Differential requirements of Rab5 and Rab7 for endocytosis of influenza and other enveloped viruses. Traffic 4:333–343. http://dx.doi.org/10.1034/j.1600-0854.2003.00090.x.
-
(2003)
Traffic
, vol.4
, pp. 333-343
-
-
Sieczkarski, S.B.1
Whittaker, G.R.2
-
34
-
-
58149390171
-
Host cell factors and functions involved in vesicular stomatitis virus entry
-
Johannsdottir HK, Mancini R, Kartenbeck J, Amato L, Helenius A. 2009. Host cell factors and functions involved in vesicular stomatitis virus entry. J Virol 83:440–453. http://dx.doi.org/10.1128/JVI.01864-08.
-
(2009)
J Virol
, vol.83
, pp. 440-453
-
-
Johannsdottir, H.K.1
Mancini, R.2
Kartenbeck, J.3
Amato, L.4
Helenius, A.5
-
35
-
-
33645788357
-
Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein
-
Schornberg K, Matsuyama S, Kabsch K, Delos S, Bouton A, White J. 2006. Role of endosomal cathepsins in entry mediated by the Ebola virus glycoprotein. J Virol 80:4174–4178. http://dx.doi.org/10.1128/JVI.80.8.4174-4178.2006.
-
(2006)
J Virol
, vol.80
, pp. 4174-4178
-
-
Schornberg, K.1
Matsuyama, S.2
Kabsch, K.3
Delos, S.4
Bouton, A.5
White, J.6
-
36
-
-
0031954296
-
Characterization of Ebola virus entry by using pseudotyped viruses: Identification of receptor-deficient cell lines
-
Wool-Lewis RJ, Bates P. 1998. Characterization of Ebola virus entry by using pseudotyped viruses: identification of receptor-deficient cell lines. J Virol 72:3155–3160.
-
(1998)
J Virol
, vol.72
, pp. 3155-3160
-
-
Wool-Lewis, R.J.1
Bates, P.2
-
37
-
-
38449106461
-
Analysis of filovirus entry into vero E6 cells, using inhibitors of endocytosis, endosomal acidification, structural integrity, and cathepsin (B and L) activity
-
Sanchez A. 2007. Analysis of filovirus entry into vero E6 cells, using inhibitors of endocytosis, endosomal acidification, structural integrity, and cathepsin (B and L) activity. J Infect Dis 196(Suppl 2):S364–S371. http://dx.doi.org/10.1086/520597.
-
(2007)
J Infect Dis
, vol.196
, pp. S364-S371
-
-
Sanchez, A.1
-
38
-
-
82755161948
-
Cysteine cathepsins: From structure, function and regulation to new frontiers
-
Turk V, Stoka V, Vasiljeva O, Renko M, Sun T, Turk B, Turk D. 2012. Cysteine cathepsins: from structure, function and regulation to new frontiers. Biochim Biophys Acta 1824:68–88. http://dx.doi.org/10.1016/j.bbapap.2011.10.002.
-
(2012)
Biochim Biophys Acta
, vol.1824
, pp. 68-88
-
-
Turk, V.1
Stoka, V.2
Vasiljeva, O.3
Renko, M.4
Sun, T.5
Turk, B.6
Turk, D.7
-
39
-
-
79960606069
-
Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2
-
Gregory SM, Harada E, Liang B, Delos SE, White JM, Tamm LK. 2011. Structure and function of the complete internal fusion loop from Ebolavirus glycoprotein 2. Proc Natl Acad Sci U S A 108:11211–11216. http://dx.doi.org/10.1073/pnas.1104760108.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 11211-11216
-
-
Gregory, S.M.1
Harada, E.2
Liang, B.3
Delos, S.E.4
White, J.M.5
Tamm, L.K.6
-
40
-
-
84860389311
-
Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: Stability and pH effects
-
Harrison JS, Higgins CD, Chandran K, Lai JR. 2011. Designed protein mimics of the Ebola virus glycoprotein GP2 α-helical bundle: stability and pH effects. Protein Sci 20:1587–1596. http://dx.doi.org/10.1002/pro.688.
-
(2011)
Protein Sci
, vol.20
, pp. 1587-1596
-
-
Harrison, J.S.1
Higgins, C.D.2
Chandran, K.3
Lai, J.R.4
-
41
-
-
84863230082
-
Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences
-
Misasi J, Chandran K, Yang JY, Considine B, Filone CM, Côté M, Sullivan N, Fabozzi G, Hensley L, Cunningham J. 2012. Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences. J Virol 86:3284–3293. http://dx.doi.org/10.1128/JVI.06346-11.
-
(2012)
J Virol
, vol.86
, pp. 3284-3293
-
-
Misasi, J.1
Chandran, K.2
Yang, J.Y.3
Considine, B.4
Filone, C.M.5
Côté, M.6
Sullivan, N.7
Fabozzi, G.8
Hensley, L.9
Cunningham, J.10
-
42
-
-
0033039502
-
Ebola virus can be effectively neutralized by antibody produced in natural human infection
-
Maruyama T, Rodriguez LL, Jahrling PB, Sanchez A, Khan AS, Nichol ST, Peters CJ, Parren PW, Burton DR. 1999. Ebola virus can be effectively neutralized by antibody produced in natural human infection. J Virol 73:6024–6030.
-
(1999)
J Virol
, vol.73
, pp. 6024-6030
-
-
Maruyama, T.1
Rodriguez, L.L.2
Jahrling, P.B.3
Sanchez, A.4
Khan, A.S.5
Nichol, S.T.6
Peters, C.J.7
Parren, P.W.8
Burton, D.R.9
-
43
-
-
80054837546
-
Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies
-
Qiu X, Alimonti JB, Melito PL, Fernando L, Ströher U, Jones SM. 2011. Characterization of Zaire ebolavirus glycoprotein-specific monoclonal antibodies. Clin Immunol 141:218–227. http://dx.doi.org/10.1016/j.clim.2011.08.008.
-
(2011)
Clin Immunol
, vol.141
, pp. 218-227
-
-
Qiu, X.1
Alimonti, J.B.2
Melito, P.L.3
Fernando, L.4
Ströher, U.5
Jones, S.M.6
-
44
-
-
84914127561
-
Structures of protective antibodies reveal sites of vulnerability on Ebola virus
-
Murin CD, Fusco ML, Bornholdt ZA, Qiu X, Olinger GG, Zeitlin L, Kobinger GP, Ward AB, Saphire EO. 2014. Structures of protective antibodies reveal sites of vulnerability on Ebola virus. Proc Natl Acad SciU S A 111:17182–17187. http://dx.doi.org/10.1073/pnas.1414164111.
-
(2014)
Proc Natl Acad Sciu S A
, vol.111
, pp. 17182-17187
-
-
Murin, C.D.1
Fusco, M.L.2
Bornholdt, Z.A.3
Qiu, X.4
Olinger, G.G.5
Zeitlin, L.6
Kobinger, G.P.7
Ward, A.B.8
Saphire, E.O.9
-
45
-
-
84922806645
-
Molecular characterization of the monoclonal antibodies composing ZMAb: A protective cocktail against Ebola virus
-
Audet J, Wong G, Wang H, Gao G, Kobinger GF, Qiu X. 2014. Molecular characterization of the monoclonal antibodies composing ZMAb: a protective cocktail against Ebola virus. Sci Rep 4:6881. http://dx.doi.org/10.1038/srep06881.
-
(2014)
Sci Rep
, vol.4
, pp. 6881
-
-
Audet, J.1
Wong, G.2
Wang, H.3
Gao, G.4
Kobinger, G.F.5
Qiu, X.6
-
46
-
-
84870613982
-
Niemann-pick C1 (NPC1)/NPC1-like chimeras define sequences critical for NPC1’s function as a filovirus entry receptor
-
Krishnan A, Miller EH, Herbert AS, Ng M, Ndungo E, Whelan SP, Dye JM, Chandran K. 2012. Niemann-pick C1 (NPC1)/NPC1-like chimeras define sequences critical for NPC1’s function as a filovirus entry receptor. Viruses 4:2471–2484. http://dx.doi.org/10.3390/v4112471.
-
(2012)
Viruses
, vol.4
, pp. 2471-2484
-
-
Krishnan, A.1
Miller, E.H.2
Herbert, A.S.3
Ng, M.4
Ndungo, E.5
Whelan, S.P.6
Dye, J.M.7
Chandran, K.8
-
47
-
-
16244391124
-
Comprehensive analysis of Ebola virus GP1 in viral entry
-
Manicassamy B, Wang J, Jiang H, Rong L. 2005. Comprehensive analysis of Ebola virus GP1 in viral entry. J Virol 79:4793–4805. http://dx.doi.org/10.1128/JVI.79.8.4793-4805.2005.
-
(2005)
J Virol
, vol.79
, pp. 4793-4805
-
-
Manicassamy, B.1
Wang, J.2
Jiang, H.3
Rong, L.4
-
48
-
-
63149192804
-
The primed Ebolavirus glycoprotein (19-kilodalton GP1,2): Sequence and residues critical for host cell binding
-
Dube D, Brecher MB, Delos SE, Rose SC, Park EW, Schornberg KL, Kuhn JH, White JM. 2009. The primed Ebolavirus glycoprotein (19-kilodalton GP1,2): sequence and residues critical for host cell binding. J Virol 83:2883–2891. http://dx.doi.org/10.1128/JVI.01956-08.
-
(2009)
J Virol
, vol.83
, pp. 2883-2891
-
-
Dube, D.1
Brecher, M.B.2
Delos, S.E.3
Rose, S.C.4
Park, E.W.5
Schornberg, K.L.6
Kuhn, J.H.7
White, J.M.8
-
49
-
-
0032887393
-
Niemann-pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network
-
Higgins ME, Davies JP, Chen FW, Ioannou YA. 1999. Niemann-pick C1 is a late endosome-resident protein that transiently associates with lysosomes and the trans-Golgi network. Mol Genet Metab 68:1–13. http://dx.doi.org/10.1006/mgme.1999.2882.
-
(1999)
Mol Genet Metab
, vol.68
, pp. 1-13
-
-
Higgins, M.E.1
Davies, J.P.2
Chen, F.W.3
Ioannou, Y.A.4
-
50
-
-
84923815384
-
Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment
-
Sakurai Y, Kolokoltsov AA, Chen CC, Tidwell MW, Bauta WE, Klugbauer N, Grimm C, Wahl-Schott C, Biel M, Davey RA. 2015. Two-pore channels control Ebola virus host cell entry and are drug targets for disease treatment. Science 347:995–998. http://dx.doi.org/10.1126/science.1258758.
-
(2015)
Science
, vol.347
, pp. 995-998
-
-
Sakurai, Y.1
Kolokoltsov, A.A.2
Chen, C.C.3
Tidwell, M.W.4
Bauta, W.E.5
Klugbauer, N.6
Grimm, C.7
Wahl-Schott, C.8
Biel, M.9
Davey, R.A.10
-
51
-
-
77951205549
-
Purified TPC isoforms form NAADP receptors with distinct roles in Ca2_ signaling ad endolysosomal trafficking
-
Ruas M, Rietdorf K, Arredouani A, Davis LC, Lloyd-Evans E, Koegel H, Funnell TM, Morgan AJ, Ward JA, Watanabe K, Cheng X, Churchill GC, Zhu MX, Platt FM, Wessel GM, Parrington J, Galione A. 2010. Purified TPC isoforms form NAADP receptors with distinct roles in Ca2_ signaling ad endolysosomal trafficking. Curr Biol 20:703–709. http://dx.doi.org/10.1016/j.cub.2010.02.049.
-
(2010)
Curr Biol
, vol.20
, pp. 703-709
-
-
Ruas, M.1
Rietdorf, K.2
Arredouani, A.3
Davis, L.C.4
Lloyd-Evans, E.5
Koegel, H.6
Funnell, T.M.7
Morgan, A.J.8
Ward, J.A.9
Watanabe, K.10
Cheng, X.11
Churchill, G.C.12
Zhu, M.X.13
Platt, F.M.14
Wessel, G.M.15
Parrington, J.16
Galione, A.17
-
52
-
-
84923050027
-
Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: Evidence that transport to NPC1+ endolysosomes is a rate-defining step
-
Mingo RM, Simmons JA, Shoemaker CJ, Nelson EA, Schornberg KL, D’Souza RS, Casanova JE, White JM. 2015. Ebola virus and severe acute respiratory syndrome coronavirus display late cell entry kinetics: evidence that transport to NPC1+ endolysosomes is a rate-defining step. J Virol 89:2931–2943. http://dx.doi.org/10.1128/JVI.03398-14.
-
(2015)
J Virol
, vol.89
, pp. 2931-2943
-
-
Mingo, R.M.1
Simmons, J.A.2
Shoemaker, C.J.3
Nelson, E.A.4
Schornberg, K.L.5
D’Souza, R.S.6
Casanova, J.E.7
White, J.M.8
-
53
-
-
84953897258
-
The ebolavirus glycoprotein directs fusion through NPC1+endolysosomes
-
Simmons JA, D’Souza RS, Ruas M, Galione A, Casanova JE, White JM. 2015. The ebolavirus glycoprotein directs fusion through NPC1+endolysosomes. J Virol 90:605–610. http://dx.doi.org/10.1128/JVI.01828-15.
-
(2015)
J Virol
, vol.90
, pp. 605-610
-
-
Simmons, J.A.1
D’Souza, R.S.2
Ruas, M.3
Galione, A.4
Casanova, J.E.5
White, J.M.6
-
54
-
-
84863393651
-
Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change
-
Brecher M, Schornberg KL, Delos SE, Fusco ML, Saphire EO, White JM. 2012. Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change. J Virol 86: 364–372. http://dx.doi.org/10.1128/JVI.05708-11.
-
(2012)
J Virol
, vol.86
, pp. 364-372
-
-
Brecher, M.1
Schornberg, K.L.2
Delos, S.E.3
Fusco, M.L.4
Saphire, E.O.5
White, J.M.6
-
55
-
-
84901350351
-
Ebolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop
-
Gregory SM, Larsson P, Nelson EA, Kasson PM, White JM, Tamm LK. 2014. Ebolavirus entry requires a compact hydrophobic fist at the tip of the fusion loop. J Virol 88:6636–6649. http://dx.doi.org/10.1128/JVI.00396-14.
-
(2014)
J Virol
, vol.88
, pp. 6636-6649
-
-
Gregory, S.M.1
Larsson, P.2
Nelson, E.A.3
Kasson, P.M.4
White, J.M.5
Tamm, L.K.6
-
56
-
-
50849144350
-
Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus
-
Saeed MF, Kolokoltsov AA, Freiberg AN, Holbrook MR, Davey RA. 2008. Phosphoinositide-3 kinase-Akt pathway controls cellular entry of Ebola virus. PLoS Pathog 4:e1000141. http://dx.doi.org/10.1371/journal.ppat.1000141.
-
(2008)
Plos Pathog
, vol.4
-
-
Saeed, M.F.1
Kolokoltsov, A.A.2
Freiberg, A.N.3
Holbrook, M.R.4
Davey, R.A.5
-
57
-
-
84914165942
-
Relating influenza virus membrane fusion kinetics to stoichiometry of neutralizing antibodies at the single-particle level
-
Otterstrom JJ, Brandenburg B, Koldijk MH, Juraszek J, Tang C, Mashaghi S, Kwaks T, Goudsmit J, Vogels R, Friesen RH, van Oijen AM. 2014. Relating influenza virus membrane fusion kinetics to stoichiometry of neutralizing antibodies at the single-particle level. Proc Natl Acad Sci U S A 111:—E5143–E5148. http://dx.doi.org/10.1073/pnas.1411755111.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
-
-
Otterstrom, J.J.1
Brandenburg, B.2
Koldijk, M.H.3
Juraszek, J.4
Tang, C.5
Mashaghi, S.6
Kwaks, T.7
Goudsmit, J.8
Vogels, R.9
Friesen, R.H.10
Van Oijen, A.M.11
-
58
-
-
58049198443
-
Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM_ memory B cells
-
Throsby M, van den Brink E, Jongeneelen M, Poon LL, Alard P, Cornelissen L, Bakker A, Cox F, van Deventer E, Guan Y, Cinatl J, ter Meulen J, Lasters I, Carsetti R, Peiris M, de Kruif J, Goudsmit J. 2008. Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM_ memory B cells. PLoS One 3:e3942. http://dx.doi.org/10.1371/journal.pone.0003942.
-
(2008)
Plos One
, vol.3
-
-
Throsby, M.1
Van Den Brink, E.2
Jongeneelen, M.3
Poon, L.L.4
Alard, P.5
Cornelissen, L.6
Bakker, A.7
Cox, F.8
Van Deventer, E.9
Guan, Y.10
Cinatl, J.11
Ter Meulen, J.12
Lasters, I.13
Carsetti, R.14
Peiris, M.15
De Kruif, J.16
Goudsmit, J.17
-
59
-
-
80051635697
-
A highly conserved neutralizing epitope on group 2 influenza A viruses
-
Ekiert DC, Friesen RHE, Bhabha G, Kwaks T, Jongeneelen M, Yu W, Ophorst C, Cox F, Korse HJWM, Brandenburg B, Vogels R, Brakenhoff JPJ, Kompier R, Koldijk MH, Cornelissen LAHM, Poon LLM, Peiris M, Koudstaal W, Wilson IA, Goudsmit J. 2011. A highly conserved neutralizing epitope on group 2 influenza A viruses. Science 333:843–850. http://dx.doi.org/10.1126/science.1204839.
-
(2011)
Science
, vol.333
, pp. 843-850
-
-
Ekiert, D.C.1
Friesen, R.2
Bhabha, G.3
Kwaks, T.4
Jongeneelen, M.5
Yu, W.6
Ophorst, C.7
Cox, F.8
Korse, H.9
Brandenburg, B.10
Vogels, R.11
Brakenhoff, J.12
Kompier, R.13
Koldijk, M.H.14
Cornelissen, L.15
Poon, L.16
Peiris, M.17
Koudstaal, W.18
Wilson, I.A.19
Goudsmit, J.20
more..
-
60
-
-
72849133481
-
A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alters its protease dependence during cell entry
-
Wong AC, Sandesara RG, Mulherkar N, Whelan SP, Chandran K. 2010. A forward genetic strategy reveals destabilizing mutations in the Ebolavirus glycoprotein that alters its protease dependence during cell entry. J Virol 84:163–175. http://dx.doi.org/10.1128/JVI.01832-09.
-
(2010)
J Virol
, vol.84
, pp. 163-175
-
-
Wong, A.C.1
Sandesara, R.G.2
Mulherkar, N.3
Whelan, S.P.4
Chandran, K.5
-
61
-
-
0033697734
-
Retroviral entry mediated by receptor priming and lowpHtriggering of an envelope glycoprotein
-
Mothes W, Boerger AL, Narayan S, Cunningham JM, Young JA. 2000. Retroviral entry mediated by receptor priming and lowpHtriggering of an envelope glycoprotein. Cell 103:679–689. http://dx.doi.org/10.1016/S0092-8674(00)00170-7.
-
(2000)
Cell
, vol.103
, pp. 679-689
-
-
Mothes, W.1
Boerger, A.L.2
Narayan, S.3
Cunningham, J.M.4
Young, J.A.5
-
62
-
-
84873734105
-
RNA-guided human genome engineering via Cas9
-
Mali P, Yang L, Esvelt KM, Aach J, Guell M, DiCarlo JE, Norville JE, Church GM. 2013. RNA-guided human genome engineering via Cas9. Science 339:823–826. http://dx.doi.org/10.1126/science.1232033.
-
(2013)
Science
, vol.339
, pp. 823-826
-
-
Mali, P.1
Yang, L.2
Esvelt, K.M.3
Aach, J.4
Guell, M.5
Dicarlo, J.E.6
Norville, J.E.7
Church, G.M.8
-
63
-
-
33947310214
-
Antibody internalization studied using a novel IgG binding toxin fusion
-
Mazor Y, Barnea I, Keydar I, Benhar I. 2007. Antibody internalization studied using a novel IgG binding toxin fusion. J Immunol Methods 321: 41–59. http://dx.doi.org/10.1016/j.jim.2007.01.008.
-
(2007)
J Immunol Methods
, vol.321
, pp. 41-59
-
-
Mazor, Y.1
Barnea, I.2
Keydar, I.3
Benhar, I.4
-
64
-
-
84864089013
-
Synthetic human monoclonal antibodies toward staphylococcal enterotoxin B (SEB) protective against toxic shock syndrome
-
Karauzum H, Chen G, Abaandou L, Mahmoudieh M, Boroun AR, Shulenin S, Devi VS, Stavale E, Warfield KL, Zeitlin L, Roy CJ, Sidhu SS, Aman MJ. 2012. Synthetic human monoclonal antibodies toward staphylococcal enterotoxin B (SEB) protective against toxic shock syndrome. J Biol Chem 287:25203–25215. http://dx.doi.org/10.1074/jbc.M112.364075.
-
(2012)
J Biol Chem
, vol.287
, pp. 25203-25215
-
-
Karauzum, H.1
Chen, G.2
Abaandou, L.3
Mahmoudieh, M.4
Boroun, A.R.5
Shulenin, S.6
Devi, V.S.7
Stavale, E.8
Warfield, K.L.9
Zeitlin, L.10
Roy, C.J.11
Sidhu, S.S.12
Aman, M.J.13
|