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Volumn 4, Issue 3, 2015, Pages 223-227

Improved overall survival following tyrosine kinase inhibitor treatment in advanced or metastatic non-small-cell lung cancer-the Holy Grail in cancer treatment?

Author keywords

Editorial; Gefitinib; Maintenance therapy; Non small cell lung cancer (NSCLC); Overall survival (OS)

Indexed keywords


EID: 84960126831     PISSN: 22186751     EISSN: 22264477     Source Type: Journal    
DOI: 10.3978/j.issn.2218-6751.2015.03.01     Document Type: Editorial
Times cited : (23)

References (23)
  • 1
    • 84929687699 scopus 로고    scopus 로고
    • Targeted therapy for NSCLC-a doubleedged sword?
    • Dempke WC. Targeted therapy for NSCLC-a doubleedged sword? Anticancer Res 2015;35:2503-12
    • (2015) Anticancer Res , vol.35 , pp. 2503-2512
    • Dempke, W.C.1
  • 2
    • 0037050352 scopus 로고    scopus 로고
    • Comparison of four chemotherapy regimens for advanced non-smallcell lung cancer
    • Schiller JH, Harrington D, Belani CP, et al. Comparison of four chemotherapy regimens for advanced non-smallcell lung cancer. N Engl J Med 2002;346:92-8
    • (2002) N Engl J Med , vol.346 , pp. 92-98
    • Schiller, J.H.1    Harrington, D.2    Belani, C.P.3
  • 3
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer
    • Scagliotti GV, Parikh P, Von Pawel J, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer. J Clin Oncol 2008;26:3543-51
    • (2008) J Clin Oncol , vol.26 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    Von Pawel, J.3
  • 4
    • 84885924300 scopus 로고    scopus 로고
    • PARAMOUNT: Final overall survival results of the phase III study of maintenance pemetrexed versus placebo immediately after induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer
    • Paz-Ares LG, de Marinis F, Dediu M, et al. PARAMOUNT: Final overall survival results of the phase III study of maintenance pemetrexed versus placebo immediately after induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small-cell lung cancer. J Clin Oncol 2013;31:2895-902
    • (2013) J Clin Oncol , vol.31 , pp. 2895-2902
    • Paz-Ares, L.G.1    de Marinis, F.2    Dediu, M.3
  • 5
    • 84877291745 scopus 로고    scopus 로고
    • Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: A meta-analysis
    • Lee CK, Brown C, Gralla RJ, et al. Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis. J Natl Cancer Inst 2013;105:595-605
    • (2013) J Natl Cancer Inst , vol.105 , pp. 595-605
    • Lee, C.K.1    Brown, C.2    Gralla, R.J.3
  • 6
    • 70350225538 scopus 로고    scopus 로고
    • Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: A randomised, double-blind, phase 3 study
    • Ciuleanu T, Brodowicz T, Zielinski C, et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. Lancet 2009;374:1432-40
    • (2009) Lancet , vol.374 , pp. 1432-1440
    • Ciuleanu, T.1    Brodowicz, T.2    Zielinski, C.3
  • 7
    • 77953541527 scopus 로고    scopus 로고
    • Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: A multicentre, randomised, placebo-controlled phase 3 study
    • Cappuzzo F, Ciuleanu T, Stelmakh L, et al. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study. Lancet Oncol 2010;11:521-9
    • (2010) Lancet Oncol , vol.11 , pp. 521-529
    • Cappuzzo, F.1    Ciuleanu, T.2    Stelmakh, L.3
  • 8
    • 84860479704 scopus 로고    scopus 로고
    • Gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804): A multicentre, double-blind randomised phase 3 trial
    • Zhang L, Ma S, Song X, et al. Gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804): a multicentre, double-blind randomised phase 3 trial. Lancet Oncol 2012;13:466-75
    • (2012) Lancet Oncol , vol.13 , pp. 466-475
    • Zhang, L.1    Ma, S.2    Song, X.3
  • 9
    • 84929675940 scopus 로고    scopus 로고
    • Gefitinib in non-small-cell lung cancer- an old lesson new re-visited
    • Dempke WC. Gefitinib in non-small-cell lung cancer- an old lesson new re-visited. Transl Lung Cancer Res 2013;2:435-8
    • (2013) Transl Lung Cancer Res , vol.2 , pp. 435-438
    • Dempke, W.C.1
  • 10
    • 84930934298 scopus 로고    scopus 로고
    • Final overall survival results from a phase III, randomised, placebo-controlled, parallelgroup study of gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804)
    • Zhao H, Fan Y, Ma S, et al. Final overall survival results from a phase III, randomised, placebo-controlled, parallelgroup study of gefitinib versus placebo as maintenance therapy in patients with locally advanced or metastatic non-small-cell lung cancer (INFORM; C-TONG 0804). J Thorac Oncol 2015;10:655-64
    • (2015) J Thorac Oncol , vol.10 , pp. 655-664
    • Zhao, H.1    Fan, Y.2    Ma, S.3
  • 11
    • 84857882376 scopus 로고    scopus 로고
    • Antiangiogenic agents in the management of non-small cell lung cancer: Where do we stand now and where are we headed?
    • Aggarwal C, Somaiah N, Simon G. Antiangiogenic agents in the management of non-small cell lung cancer: where do we stand now and where are we headed? Cancer Biol Ther 2012;13:247-63
    • (2012) Cancer Biol Ther , vol.13 , pp. 247-263
    • Aggarwal, C.1    Somaiah, N.2    Simon, G.3
  • 12
    • 33746388176 scopus 로고    scopus 로고
    • "Oncogenic shock": Explaining oncogene addiction through differential signal attenuation
    • Sharma SV, Fischbach MA, Haber DA, et al. "Oncogenic shock": explaining oncogene addiction through differential signal attenuation. Clin Cancer Res 2006;12:4392s-5s
    • (2006) Clin Cancer Res , vol.12 , pp. 4392s-4395s
    • Sharma, S.V.1    Fischbach, M.A.2    Haber, D.A.3
  • 13
    • 84857502654 scopus 로고    scopus 로고
    • Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, open-label, randomised phase 3 trial
    • Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, open-label, randomised phase 3 trial. Lancet Oncol 2012;13:239-46
    • (2012) Lancet Oncol , vol.13 , pp. 239-246
    • Rosell, R.1    Carcereny, E.2    Gervais, R.3
  • 14
    • 79960889662 scopus 로고    scopus 로고
    • Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
    • Zhou C, Wu YL, Chen G, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol 2011;12:735-42
    • (2011) Lancet Oncol , vol.12 , pp. 735-742
    • Zhou, C.1    Wu, Y.L.2    Chen, G.3
  • 15
    • 69949162760 scopus 로고    scopus 로고
    • Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
    • Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-57
    • (2009) N Engl J Med , vol.361 , pp. 947-957
    • Mok, T.S.1    Wu, Y.L.2    Thongprasert, S.3
  • 16
    • 84871597401 scopus 로고    scopus 로고
    • Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin-paclitaxel for chemonaïve non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002)
    • Inoue A, Kobayashi K, Maemondo M, et al. Updated overall survival results from a randomized phase III trial comparing gefitinib with carboplatin-paclitaxel for chemonaïve non-small cell lung cancer with sensitive EGFR gene mutations (NEJ002). Ann Oncol 2013;24:54-9
    • (2013) Ann Oncol , vol.24 , pp. 54-59
    • Inoue, A.1    Kobayashi, K.2    Maemondo, M.3
  • 17
    • 84861976809 scopus 로고    scopus 로고
    • First-SIGNAL: First-line single-agent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung
    • Han JY, Park K, Kim SW, et al. First-SIGNAL: first-line single-agent iressa versus gemcitabine and cisplatin trial in never-smokers with adenocarcinoma of the lung. J Clin Oncol 2012;30:1122-8
    • (2012) J Clin Oncol , vol.30 , pp. 1122-1128
    • Han, J.Y.1    Park, K.2    Kim, S.W.3
  • 18
    • 84921525233 scopus 로고    scopus 로고
    • Final overall survival results of WJTOG3405, a randomized phase 3 trial comparing gefitinib (G) with cisplatin plus docetaxel (CD) as the first-line treatment for patients with non-small cell lung cancer (NSCLC) harbouring mutations of the epidermal growth factor receptor (EGFR)
    • Yoshioka H, Mitsudomi T, Morita S, et al. Final overall survival results of WJTOG3405, a randomized phase 3 trial comparing gefitinib (G) with cisplatin plus docetaxel (CD) as the first-line treatment for patients with non-small cell lung cancer (NSCLC) harbouring mutations of the epidermal growth factor receptor (EGFR). J Clin Oncol 2014;32:5s
    • (2014) J Clin Oncol , vol.32 , pp. 5s
    • Yoshioka, H.1    Mitsudomi, T.2    Morita, S.3
  • 19
    • 84884736973 scopus 로고    scopus 로고
    • Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations
    • Sequist LV, Yang JC, Yamamoto N, et al. Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations. J Clin Oncol 2013;31:3327-34
    • (2013) J Clin Oncol , vol.31 , pp. 3327-3334
    • Sequist, L.V.1    Yang, J.C.2    Yamamoto, N.3
  • 20
    • 84892997539 scopus 로고    scopus 로고
    • Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): An open-label, randomised phase 3 trial
    • Wu YL, Zhou C, Hu CP, et al. Afatinib versus cisplatin plus gemcitabine for first-line treatment of Asian patients with advanced non-small-cell lung cancer harbouring EGFR mutations (LUX-Lung 6): an open-label, randomised phase 3 trial. Lancet Oncol 2014;15:213-22
    • (2014) Lancet Oncol , vol.15 , pp. 213-222
    • Wu, Y.L.1    Zhou, C.2    Hu, C.P.3
  • 21
    • 84921892043 scopus 로고    scopus 로고
    • Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): Analysis of overall survival data from two randomised, phase 3 trials
    • Yang JC, Wu YL, Schuler M, et al. Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials. Lancet Oncol 2015;16:141-51
    • (2015) Lancet Oncol , vol.16 , pp. 141-151
    • Yang, J.C.1    Wu, Y.L.2    Schuler, M.3
  • 22
    • 84921864537 scopus 로고    scopus 로고
    • LUX-Lung: Determining the best EGFR inhibitor in NSCLC?
    • Rossi A, Di Maio M. LUX-Lung: determining the best EGFR inhibitor in NSCLC? Lancet Oncol 2015;16:118-9
    • (2015) Lancet Oncol , vol.16 , pp. 118-119
    • Rossi, A.1    Di Maio, M.2
  • 23
    • 84871037359 scopus 로고    scopus 로고
    • Progression-free survival and overall survival in phase III trials of moleculartargeted agents in advanced non-small-cell lung cancer
    • Hotta K, Suzuki E, Di Maio M, et al. Progression-free survival and overall survival in phase III trials of moleculartargeted agents in advanced non-small-cell lung cancer. Lung Cancer 2013;79:20-6.
    • (2013) Lung Cancer , vol.79 , pp. 20-26
    • Hotta, K.1    Suzuki, E.2    Di Maio, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.