Associations of Sarcopenic Obesity and Dynapenic Obesity with Bone Mineral Density and Incident Fractures Over 5–10 Years in Community-Dwelling Older Adults

Calcified Tissue International

Volumn 99, Issue 1, 2016, Pages 30-42

  Scott, David ^a,b   Chandrasekara, Sahan D ^a   Laslett, Laura L ^c   Cicuttini, Flavia ^a   Ebeling, Peter R ^a,b   Jones, Graeme ^c  

^a MONASH UNIVERSITY   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF TASMANIA   (Australia)

Author keywords

Dynapenia; Fracture; Obesity; Osteoporosis; Sarcopenia

Indexed keywords

ADULT; ARTICLE; BODY FAT; BODY MASS; BONE DENSITY; CONTROLLED STUDY; DYNAPENIC OBESITY; FAT MASS; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MUSCLE MASS; MUSCLE STRENGTH; NON VERTEBRAL FRACTURE; OBESITY; OSTEOPENIA; OSTEOPOROSIS; PHYSICAL ACTIVITY; PREVALENCE; PRIORITY JOURNAL; SARCOPENIA; SARCOPENIC OBESITY; SPINE FRACTURE; WAIST CIRCUMFERENCE; AGED; AGING; BODY COMPOSITION; COMPLICATION; FRACTURE; HAND STRENGTH; PHYSIOLOGY; RISK FACTOR;

AGED; AGING; BODY COMPOSITION; BONE DENSITY; FEMALE; FRACTURES, BONE; HAND STRENGTH; HUMANS; MALE; MIDDLE AGED; MUSCLE STRENGTH; OBESITY; RISK FACTORS; SARCOPENIA;

EID: 84960101736     PISSN: 0171967X     EISSN: 14320827     Source Type: Journal    
DOI: 10.1007/s00223-016-0123-9     Document Type: Article

References (34)

1. Rosenberg IH (1989) Summary comments. Am J Clin Nutr 50:1231–1233
2. Delmonico MJ, Harris TB, Visser M et al (2009) Longitudinal study of muscle strength, quality, and adipose tissue infiltration. Am J Clin Nutr 90:1579–1585
3. Visser M, Schaap LA (2011) Consequences of sarcopenia. Clin Geriatr Med 27:387–399
4. Clark BC, Manini TM (2008) Sarcopenia ≠ dynapenia. J Gerontol A Biol Sci Med Sci 63:829–834
5. Scott D, Daly RM, Sanders KM, Ebeling PR (2015) Fall and fracture risk in sarcopenia and dynapenia with and without obesity: the role of lifestyle interventions. Curr Osteoporos Rep 13:235–244
6. Edwards MH, Gregson CL, Patel HP, Jameson KA, Harvey NC, Sayer AA, Dennison EM, Cooper C (2013) Muscle size, strength and physical performance and their associations with bone structure in the Hertfordshire Cohort Study. J Bone Miner Res 28:2295–2304
7. Mitchell RJ, Lord SR, Harvey LA, Close JC (2014) Associations between obesity and overweight and fall risk, health status and quality of life in older people. Aust N Z J Public Health 38:13–18
8. Compston JE, Watts NB, Chapurlat R, Cooper C, Boonen S, Greenspan S, Pfeilschifter J, Silverman S, Díez-Pérez A, Lindsay R (2011) Obesity is not protective against fracture in postmenopausal women: GLOW. Am J Med 124:1043–1050
9. Nielson CM, Srikanth P, Orwoll ES (2012) Obesity and fracture in men and women: an epidemiologic perspective. J Bone Miner Res 27:1–10
10. Waters D, Hale L, Grant A, Herbison P, Goulding A (2010) Osteoporosis and gait and balance disturbances in older sarcopenic obese New Zealanders. Osteoporos Int 21:351–357
11. Scott D, Sanders K, Aitken D, Hayes A, Ebeling PR, Jones G (2014) Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults. Obesity 22:1568–1574
12. Scott D, Blizzard L, Fell J, Jones G (2012) Prospective study of self-reported pain, radiographic osteoarthritis, sarcopenia progression, and falls risk in community-dwelling older adults. Arthritis Care Res 64:30–37
13. Hodge A, Patterson AJ, Brown WJ, Ireland P, Giles G (2000) The Anti Cancer Council of Victoria FFQ: relative validity of nutrient intakes compared with weighed food records in young to middle-aged women in a study of iron supplementation. Aust N Z J Public Health 24:576–583
14. Scott D, Blizzard L, Fell J, Jones G (2009) Ambulatory activity, body composition and lower-limb muscle strength in older adults. Med Sci Sports Exerc 41:383–389
15. Scott D, Blizzard L, Fell J, Jones G (2011) Prospective associations between ambulatory activity, body composition and muscle function in older adults. Scand J Med Sci Sports 21:e168–e175
16. Lord SR, Menz HB, Tiedemann A (2003) A physiological profile approach to falls risk assessment and prevention. Phys Ther 83:237–252
17. Foley S, Quinn S, Jones G (2010) Pedometer determined ambulatory activity and bone mass: a population-based longitudinal study in older adults. Osteoporos Int 21:1809–1816
18. Kanis J, Johnell O, Oden A, Jonsson B, De Laet C, Dawson A (2000) Risk of hip fracture according to the World Health Organization criteria for osteopenia and osteoporosis. Bone 27:585–590
19. Newman AB, Kupelian V, Visser M, Simonsick E, Goodpaster B, Nevitt M, Kritchevsky SB, Tylavsky FA, Rubin SM, Harris TB (2003) Sarcopenia: alternative definitions and associations with lower extremity function. J Am Geriatr Soc 51:1602–1609
20. Bouchard DR, Janssen I (2010) Dynapenic-obesity and physical function in older adults. J Gerontol A Biol Sci Med Sci 65:71–77
21. Sénéchal M, Dionne IJ, Brochu M (2012) Dynapenic abdominal obesity and metabolic risk factors in adults 50 years of age and older. J Aging Health 24:812–826
22. Cruz-Jentoft AJ, Baeyens JP, Bauer JM et al (2010) Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People. Age Ageing 39:412–423
23. Aubertin-Leheudre M, Lord C, Labonté M, Khalil A, Dionne IJ (2008) Relationship between sarcopenia and fracture risks in obese postmenopausal women. J Women Aging 20:297–308
24. He H, Liu Y, Tian Q, Papasian C, Hu T, Deng H-W (2015) Relationship of sarcopenia and body composition with osteoporosis. Osteoporos Int 1–10
25. Edwards MH, Ward KA, Ntani G, Parsons C, Thompson J, Sayer AA, Dennison EM, Cooper C (2015) Lean mass and fat mass have differing associations with bone microarchitecture assessed by high resolution peripheral quantitative computed tomography in men and women from the Hertfordshire Cohort Study. Bone 81:145–151
26. Sornay-Rendu E, Boutroy S, Vilayphiou N, Claustrat B, Chapurlat RD (2013) In obese postmenopausal women, bone microarchitecture and strength are not commensurate to greater body weight: the Os des Femmes de Lyon (OFELY) study. J Bone Miner Res 28:1679–1687
27. Horstman AM, Dillon EL, Urban RJ, Sheffield-Moore M (2012) The role of androgens and estrogens on healthy aging and longevity. Biological Sciences and Medical Sciences, The Journals of Gerontology Series A
28. Yang M, Jiang J, Hao Q, Luo L, Dong B (2015) Dynapenic obesity and lower extremity function in elderly adults. J Am Med Dir Assoc 16:31–36
29. Chalhoub D, Cawthon PM, Ensrud KE et al (2015) Risk of nonspine fractures in older adults with Sarcopenia, low bone mass, or both. J Am Geriatr Soc 63:1733–1740
30. Scott D, Hayes A, Sanders KM, Aitken D, Ebeling PR, Jones G (2014) Operational definitions of sarcopenia and their associations with 5-year changes in falls risk in community-dwelling middle-aged and older adults. Osteoporos Int 25:187–193
31. Andersen S, Frederiksen KD, Hansen S, Brixen K, Gram J, Støving RK (2014) Bone structure and estimated bone strength in obese patients evaluated by high-resolution peripheral quantitative computed tomography. Calcif Tissue Int 95:19–28
32. Baumgartner RN, Romero L, Garry PJ, Heymsfield SB, Koehler KM, Gallagher D, Ross RR, Lindeman RD (1998) Epidemiology of sarcopenia among the elderly in New Mexico. Am J Epidemiol 147:755–763
33. Fielding RA, Vellas B, Evans WJ et al (2011) Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International Working Group on Sarcopenia. J Am Med Dir Assoc 12:249–256
34. Studenski SA, Peters KW, Alley DE, Cawthon PM, McLean RR, Harris TB, Ferrucci L, Guralnik JM, Fragala MS, Kenny AM (2014) The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J Gerontol A Biol Sci Med Sci 69:547–558