MicroRNA-375 plays a dual role in prostate carcinogenesis

Clinical Epigenetics

Volumn 7, Issue 1, 2015, Pages 1-14

  Costa Pinheiro, Pedro ^a   Ramalho Carvalho, João ^a   Vieira, Filipa Quintela ^a,b   Torres Ferreira, Jorge ^a   Oliveira, Jorge ^a   Gonçalves, Céline S ^c,d   Costa, Bruno M ^c,d   Henrique, Rui ^a,e   Jerónimo, Carmen ^a,e  

^a PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

^b POLYTECHNIC INSTITUTE OF PORTO   (Portugal)

^c UNIVERSITY OF MINHO   (Portugal)

^d UNIVERSITY OF MINHO   (Portugal)

^e UNIVERSITY OF PORTO   (Portugal)

Author keywords

CCND2; Epigenetics; MicroRNAs; MiR 375; Prostate cancer

Indexed keywords

CYCLIN D2; MICRORNA 103 AS; MICRORNA 1200; MICRORNA 147B; MICRORNA 182; MICRORNA 200C; MICRORNA 32; MICRORNA 375; MICRORNA 496; MICRORNA 512 3P; MICRORNA 517B; MICRORNA 518C; MICRORNA 548C 5P; MICRORNA 551A; MICRORNA 562; MICRORNA 615 3P; MICRORNA 770 5P; RETINOBLASTOMA BINDING PROTEIN 1; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; APOPTOSIS; ARTICLE; CANCER GROWTH; CANCER PATIENT; CANCER STAGING; CARCINOGENESIS; CCND2 GENE; CELL CYCLE; CELL DIFFERENTIATION; CELL INVASION; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE ONTOLOGY; GENE TARGETING; GLEASON SCORE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CANCER CELL LINE; PROSTATE CARCINOGENESIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR GENE;

EID: 84960097977     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-015-0076-2     Document Type: Article

References (40)

1. Ferlay J, Steliarova-Foucher E, Lortet-Tieulent J, Rosso S, Coebergh JW, Comber H, et al. Cancer incidence and mortality patterns in Europe: estimates for 40 countries in 2012. Eur J Cancer. 2013;49(6):1374–403. doi:10.1016/j.ejca.2012.12.027.
2. Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin. 2014;64(1):9–29. doi:10.3322/caac.21208.
3. Hricak H, Scardino PT. Prostate cancer. Contemporary issues in cancer imaging. Cambridge, UK. New York: Cambridge University Press; 2009.
4. Jeronimo C, Bastian PJ, Bjartell A, Carbone GM, Catto JW, Clark SJ, et al. Epigenetics in prostate cancer: biologic and clinical relevance. Eur Urol. 2011;60(4):753–66. doi:10.1016/j.eururo.2011.06.035.
5. Porkka KP, Pfeiffer MJ, Waltering KK, Vessella RL, Tammela TL, Visakorpi T. MicroRNA expression profiling in prostate cancer. Cancer Res. 2007;67(13):6130–5. doi:10.1158/0008-5472. CAN-07-0533.
6. Croce CM. Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet. 2009;10(10):704–14. doi:10.1038/nrg2634.
7. Iorio MV, Croce CM. MicroRNAs in cancer: small molecules with a huge impact. J Clin Oncol. 2009;27(34):5848–56. doi:10.1200/JCO.2009.24.0317.
8. Kozomara A, Griffiths-Jones S. miRBase: annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res. 2014;42(Database issue):D68–73. doi:10.1093/nar/gkt1181.
9. van Rooij E, Olson EN. MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. Nat Rev Drug Discov. 2012;11(11):860–72. doi:10.1038/nrd3864.
10. Iorio MV, Croce CM. MicroRNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review. EMBO Mol Med. 2012;4(3):143–59. doi:10.1002/emmm.201100209.
11. Davalos V, Esteller M. MicroRNAs and cancer epigenetics: a macrorevolution. Curr Opin Oncol. 2010;22(1):35–45. doi:10.1097/CCO.0b013e328333dcbb.
12. Catto JW, Alcaraz A, Bjartell AS, De Vere WR, Evans CP, Fussel S, et al. MicroRNA in prostate, bladder, and kidney cancer: a systematic review. Eur Urol. 2011;59(5):671–81. doi:10.1016/j.eururo.2011.01.044.
13. Coppola V, De Maria R, Bonci D. MicroRNAs and prostate cancer. Endocr Relat Cancer. 2010;17(1):F1–F17. doi:10.1677/ERC-09-0172.
14. Shen MM, Abate-Shen C. Molecular genetics of prostate cancer: new prospects for old challenges. Genes Dev. 2010;24(18):1967–2000. doi:10.1101/gad.1965810.
15. Lewis H, Lance R, Troyer D, Beydoun H, Hadley M, Orians J, et al. miR-888 is an expressed prostatic secretions-derived microRNA that promotes prostate cell growth and migration. Cell Cycle. 2014;13(2):227–39. doi:10.4161/cc.26984.
16. Sun R, Fu X, Li Y, Xie Y, Mao Y. Global gene expression analysis reveals reduced abundance of putative microRNA targets in human prostate tumours. BMC Genomics. 2009;10:93. doi:10.1186/1471-2164-10-93.
17. Lockhart DJ, Winzeler EA. Genomics, gene expression and DNA arrays. Nature. 2000;405(6788):827–36. doi:10.1038/35015701.
18. Tsuchiyama K, Ito H, Taga M, Naganuma S, Oshinoya Y, Nagano K, et al. Expression of microRNAs associated with Gleason grading system in prostate cancer: miR-182-5p is a useful marker for high grade prostate cancer. Prostate. 2013;73(8):827–34. doi:10.1002/pros.22626.
19. Cheng HH, Mitchell PS, Kroh EM, Dowell AE, Chery L, Siddiqui J, et al. Circulating microRNA profiling identifies a subset of metastatic prostate cancer patients with evidence of cancer-associated hypoxia. PLoS One. 2013;8(7), e69239. doi:10.1371/journal.pone.0069239.
20. Nguyen HC, Xie W, Yang M, Hsieh CL, Drouin S, Lee GS, et al. Expression differences of circulating microRNAs in metastatic castration resistant prostate cancer and low-risk, localized prostate cancer. Prostate. 2013;73(4):346–54. doi:10.1002/pros.22572.
21. Huang X, Yuan T, Liang M, Du M, Xia S, Dittmar R, et al. Exosomal miR-1290 and miR-375 as prognostic markers in castration-resistant prostate cancer. Eur Urol. 2015;67(1):33–41. doi:10.1016/j.eururo.2014.07.035.
22. Szafranska AE, Davison TS, John J, Cannon T, Sipos B, Maghnouj A, et al. MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene. 2007;26(30):4442–52. doi:10.1038/sj.onc.1210228.
23. Ladeiro Y, Couchy G, Balabaud C, Bioulac-Sage P, Pelletier L, Rebouissou S, et al. MicroRNA profiling in hepatocellular tumors is associated with clinical features and oncogene/tumor suppressor gene mutations. Hepatology. 2008;47(6):1955–63. doi:10.1002/hep.22256.
24. Avissar M, Christensen BC, Kelsey KT, Marsit CJ. MicroRNA expression ratio is predictive of head and neck squamous cell carcinoma. Clin Cancer Res. 2009;15(8):2850–5. doi:10.1158/1078-0432. CCR-08-3131.
25. Tsukamoto Y, Nakada C, Noguchi T, Tanigawa M, Nguyen LT, Uchida T, et al. MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta. Cancer Res. 2010;70(6):2339–49. doi:10.1158/0008-5472. CAN-09-2777.
26. Ding L, Xu Y, Zhang W, Deng Y, Si M, Du Y, et al. MiR-375 frequently downregulated in gastric cancer inhibits cell proliferation by targeting JAK2. Cell Res. 2010;20(7):784–93. doi:10.1038/cr.2010.79.
27. Szczyrba J, Nolte E, Wach S, Kremmer E, Stohr R, Hartmann A, et al. Downregulation of Sec23A protein by miRNA-375 in prostate carcinoma. Mol Cancer Res. 2011;9(6):791–800. doi:10.1158/1541-7786. MCR-10-0573.
28. Selth LA, Townley S, Gillis JL, Ochnik AM, Murti K, Macfarlane RJ, et al. Discovery of circulating microRNAs associated with human prostate cancer using a mouse model of disease. Int J Cancer. 2012;131(3):652–61. doi:10.1002/ijc.26405.
29. Wach S, Nolte E, Szczyrba J, Stohr R, Hartmann A, Orntoft T, et al. MicroRNA profiles of prostate carcinoma detected by multiplatform microRNA screening. Int J Cancer. 2012;130(3):611–21. doi:10.1002/ijc.26064.
30. Nam JW, Rissland OS, Koppstein D, Abreu-Goodger C, Jan CH, Agarwal V, et al. Global analyses of the effect of different cellular contexts on microRNA targeting. Mol Cell. 2014;53(6):1031–43. doi:10.1016/j.molcel.2014.02.013.
31. Costa VL, Henrique R, Jeronimo C. Epigenetic markers for molecular detection of prostate cancer. Dis Markers. 2007;23(1–2):31–41.
32. Kobayashi T, Nakamura E, Shimizu Y, Terada N, Maeno A, Kobori G, et al. Restoration of cyclin D2 has an inhibitory potential on the proliferation of LNCaP cells. Biochem Biophys Res Commun. 2009;387(1):196–201. doi:10.1016/j.bbrc.2009.06.146.
33. Bettendorf O, Schmidt H, Staebler A, Grobholz R, Heinecke A, Boecker W, et al. Chromosomal imbalances, loss of heterozygosity, and immunohistochemical expression of TP53, RB1, and PTEN in intraductal cancer, intraepithelial neoplasia, and invasive adenocarcinoma of the prostate. Genes, Chromosomes Cancer. 2008;47(7):565–72. doi:10.1002/gcc.20560.
34. Chu M, Chang Y, Li P, Guo Y, Zhang K, Gao W. Androgen receptor is negatively correlated with the methylation-mediated transcriptional repression of miR-375 in human prostate cancer cells. Oncol Rep. 2014;31(1):34–40. doi:10.3892/or.2013.2810.
35. Di Leva G, Piovan C, Gasparini P, Ngankeu A, Taccioli C, Briskin D, et al. Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status. PLoS Genet. 2013;9(3), e1003311. doi:10.1371/journal.pgen.1003311.
36. DeVita VT, Lawrence TS, Rosenberg SA. Cancer: principles and practice of oncology. 5th ed. Philadelphia: Wolters Kluwer/Lippincott Williams & Wilkins; 2008.
37. Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative C (T) method. Nat Protoc. 2008;3(6):1101–8.
38. Carbon S, Ireland A, Mungall CJ, Shu S, Marshall B, Lewis S. AmiGO: online access to ontology and annotation data. Bioinformatics. 2009;25(2):288–9. doi:10.1093/bioinformatics/btn615
39. Boyle EI, Weng S, Gollub J, Jin H, Botstein D, Cherry JM, et al. GO: TermFinder - open source software for accessing Gene Ontology information and finding significantly enriched Gene Ontology terms associated with a list of genes. Bioinformatics. 2004;20(18):3710–5. doi:10.1093/bioinformatics/bth456.
40. Gonçalves C. The Cancer Genome Atlas (TCGA). http://cancergenome.nih.gov/. Accessed 2014.