Periprocedural warfarin reversal with prothrombin complex concentrate

Thrombosis Research

Volumn 139, Issue , 2016, Pages 160-165

  Sridharan, Meera ^a   Wysokinski, Waldemar E ^a   Pruthi, Rajiv ^a   Oyen, Lance ^a   Freeman, William D ^a   Rabinstein, Alejandro A ^b   McBane, Robert D ^a  

^a MAYO CLINIC   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Anticoagulants; Bleeding; Prothrombin complex concentrate (PCC); Thrombosis; Warfarin

Indexed keywords

BLOOD CLOTTING FACTOR 9 COMPLEX; FRESH FROZEN PLASMA; HEPARIN; VITAMIN K GROUP; WARFARIN; ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR; COAGULATING AGENT; PROTHROMBIN COMPLEX CONCENTRATES;

ABDOMINAL SURGERY; AGED; ANTICOAGULANT THERAPY; ARTERY EMBOLISM; ARTICLE; BLEEDING; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; DEATH; DEEP VEIN THROMBOSIS; DRUG EFFICACY; DRUG SAFETY; ENDOSCOPY; FEMALE; GASTROINTESTINAL HEMORRHAGE; HIGH RISK POPULATION; HUMAN; INTERNATIONAL NORMALIZED RATIO; INTRACARDIAC THROMBUS; INVASIVE PROCEDURE; LIMB BLEEDING; LUNG EMBOLISM; MAJOR CLINICAL STUDY; MALE; MORTALITY RATE; ORTHOPEDIC SURGERY; PERIOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RETROPERITONEAL HEMORRHAGE; SINGLE DRUG DOSE; THORAX BLEEDING; THORAX SURGERY; THROMBOEMBOLISM; THROMBUS; TRANSIENT ISCHEMIC ATTACK; VEIN THROMBOSIS; VENOUS THROMBOEMBOLISM; BLOOD CLOTTING; BLOOD LOSS, SURGICAL; CHEMICALLY INDUCED; DRUG EFFECTS; RETROSPECTIVE STUDY; SURGERY;

AGED; ANTICOAGULANTS; BLOOD COAGULATION; BLOOD COAGULATION FACTORS; BLOOD LOSS, SURGICAL; COAGULANTS; FEMALE; HUMANS; INTERNATIONAL NORMALIZED RATIO; MALE; RETROSPECTIVE STUDIES; SURGICAL PROCEDURES, OPERATIVE; THROMBOEMBOLISM; WARFARIN;

EID: 84960095858     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2015.11.024     Document Type: Article

References (35)

1. Heart Disease and Stroke Statistics-2015 Update a report from the American Heart Association Circulation 131 2015 e29 e322
2. S. Schulman, M. Carrier, A.Y. Lee, S. Shivakumar, M. Blostein, F.A. Spencer, S. Solymoss, R. Barty, G. Wang, N. Heddle, and J.D. Douketis Perioperative management of Dabigatran: A prospective cohort study Circulation 132 2015 167 173
3. D. Garcia, J.H. Alexander, L. Wallentin, D.M. Wojdyla, L. Thomas, M. Hanna, S.M. Al-khatib, P. Dorian, J. Ansell, P. Commerford, G. Flaker, F. Lanas, D. Vinereanu, D. Xavier, E.M. Hylek, C. Held, F.W. Verheugt, C.B. Granger, and R.D. Lopes Management and clinical outcomes in patients treated with apixaban vs warfarin undergoing procedures Blood 124 2014 3692 3698
4. G.H. Guyatt, E.A. Akl, M. Crowther, D.D. Gutterman, H.J. Schuünemann, and American college of chest physicians antithrombotic therapy and prevention of thrombosis panel Executive summary: Antithrombotic therapy and prevention of thrombosis, 9th ed: American college of chest physicians evidence-based clinical practice guidelines Chest 141 2 Suppl. 2012 7S 47S
5. W. Ageno, A.S. Gallus, A. Wittkowsky, M. Crowther, E.M. Hylek, G. Palareti, and American college of chest physicians Oral anticoagulant therapy: Antithrombotic therapy and prevention of thrombosis, 9th ed: American college of chest physicians evidence-based clinical practice guidelines Chest 141 2 Suppl. 2012 e44S e88S
6. J.C. Hemphill 3rd, S.M. Greenberg, C.S. Anderson, K. Becker, B.R. Bendok, M. Cushman, G.L. Fung, J.N. Goldstein, R.L. Macdonald, P.H. Mitchell, P.A. Scott, M.H. Selim, and D. Woo Guidelines for the management of spontaneous intracerebral hemorrhage: A guideline for healthcare professionals from the American Heart Association/American Stroke Association Stroke 2015 May 28 [Epub ahead of print]
7. Á. Altorjay, É. Szabó, Z. Boda, L. Kramer, L.Y. Ngo, W. Engl, C.L. Firth, E.R. Ahlstrom, D.M. Gelmont, and I. Pabinger An international, multicenter, prospective study of a prothrombin complex concentrate, prothromplex total, in anticoagulant reversal Thromb. Res. 135 2015 485 491
8. A.C. Spyropoulos, J.D. Douketis, G. Gerotziafas, S. Kaatz, T.L. Ortel, S. Schulman, and Subcommittee on control of anticoagulation of the SSC of the ISTH Periprocedural antithrombotic and bridging therapy: Recommendations for standardized reporting in patients with arterial indications for chronic oral anticoagulant therapy J. Thromb. Haemost. 10 2012 Apr 692 694
9. J.I. Tange, D. Grill, C.D. Koch, R.J. Ybabez, B.J. Krekelberg, K.A. Fylling, C.R. Wiese, N.A. Baumann, D.R. Block, B.S. Karon, D. Chen, and R.K. Pruthi Local verification and assignment of mean normal prothrombin time and International Sensitivity Index values across various instruments: Recent experience and outcome from North America Semin. Thromb. Hemost. 40 2014 115 120
10. W.E. Wysokinski, and R.D. McBane II Periprocedural bridging management of anticoagulation Circulation 126 2012 486 490
11. A.J. Tafur, R. McBane 2nd, W.E. Wysokinski, S. Litin, P. Daniels, J. Slusser, D. Hodge, M.G. Beckman, and J.A. Heit Predictors of major bleeding in peri-procedural anticoagulation management J. Thromb. Haemost. 10 2012 261 267
12. R.D. McBane, W.E. Wysokinski, P.R. Daniels, S.C. Litin, J. Slusser, D.O. Hodge, N.F. Dowling, and J.A. Heit Periprocedural anticoagulation management of patients with venous thromboembolism Arterioscler. Thromb. Vasc. Biol. 30 2010 442 448
13. P.R. Daniels, R.D. McBane, S.C. Litin, S.A. Ward, D.O. Hodge, N.F. Dowling, and J.A. Heit Peri-procedural anticoagulation management of mechanical prosthetic heart valve patients Thromb. Res. 124 2009 300 305
14. W.E. Wysokinski, R.D. McBane, P.R. Daniels, S.C. Litin, D.O. Hodge, N.F. Dowling, and J.A. Heit Periprocedural anticoagulation management of patients with nonvalvular atrial fibrillation Mayo Clin. Proc. 83 2008 639 645
15. K. Thygesen, J.S. Alpert, and H.D. White Joint ESC/ACCF/AHA/WHF task force for the redefinition of myocardial infarction. Universal definition of myocardial infarction Eur. Heart J. 28 2007 2525 2538
16. K.L. Furie, S.E. Kasner, R.J. Adams, G.W. Albers, R.L. Bush, S.C. Fagan, J.L. Halperin, S.C. Johnston, I. Katzan, W.N. Kernan, P.H. Mitchell, B. Ovbiagele, Y.Y. Palesch, R.L. Sacco, L.H. Schwamm, S. Wassertheil-Smoller, T.N. Turan, D. Wentworth, and American Heart Association Stroke Council, Council on Cardiovascular Nursing, Council on Clinical Cardiology, and Interdisciplinary Council on Quality of Care and Outcomes Research Guidelines for the prevention of stroke in patients with stroke or transient ischemic attack: A guideline for healthcare professionals from the American Heart Association/American Stroke Association Stroke 42 2011 227 276
17. S. Schulman, and C. Kearon Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients J. Thromb. Haemost. 3 2005 692 694
18. H. Attaya, N.D. Shah, W.E. Wysokinski, H.K. Van Houten, J.A. Heit, and R.D. McBane II Outcomes and total costs of outpatient vs. inpatient peri-procedural anticoagulation management of mechanical prosthetic heart valve patients Int. J. Cardiol. 168 2013 5311 5315
19. H. Attaya, W.E. Wysokinski, T. Bower, S. Litin, P.R. Daniels, J. Slusser, J.A. Heit, and R.D. McBane 2nd. Three-month cumulative incidence of thromboembolism and bleeding after periprocedural anticoagulation management of arterial vascular bypass patients J. Thromb. Thrombolysis 35 2013 100 106
20. J.S. Healey, J. Eikelboom, J. Douketis, L. Wallentin, J. Oldgren, S. Yang, E. Themeles, H. Heidbuchel, A. Avezum, P. Reilly, S.J. Connolly, S. Yusuf, M. Ezekowitz, and RE-LY investigators Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: Results from the randomized evaluation of long-term anticoagulation therapy (RE-LY) randomized trial Circulation 126 2012 343 348
21. J.A. Frontera, E. Gordon, V. Zach, M. Jovine, K. Uchino, M.S. Hussain, and L. Aledort Reversal of coagulopathy using prothrombin complex concentrates is associated with improved outcome compared to fresh frozen plasma in warfarin-associated intracranial hemorrhage Neurocrit. Care. 21 2014 397 406
22. J.B. Kuramatsu, S.T. Gerner, P.D. Schellinger, J. Glahn, M. Endres, J. Sobesky, J. Flechsenhar, H. Neugebauer, E. Jüttler, A. Grau, F. Palm, J. Röther, P. Michels, G.F. Hamann, J. Hüwel, G. Hagemann, B. Barber, C. Terborg, F. Trostdorf, H. Bäzner, and et al. Anticoagulant reversal, blood pressure levels, and anticoagulant resumption in patients with anticoagulation-related intracerebral hemorrhage J. Am. Med. Assoc. 313 2015 824 836
23. T.H. Baron, P.S. Kamath, and R.D. McBane Management of antithrombotic therapy in patients undergoing invasive procedures N. Engl. J. Med. 368 2013 2113 2124
24. K.P. Cabral, G.L. Fraser, J. Duprey, B.A. Gibbons, T. Hayes, J.E. Florman, and D.B. Seder Prothrombin complex concentrates to reverse warfarin-induced coagulopathy in patients with intracranial bleeding Clin. Neurol. Neurosurg. 115 2013 770 774
25. C.H. Woo, N. Patel, C. Conell, V.A. Rao, B.S. Faigeles, M.C. Patel, J. Pombra, P.T. Akins, Y.K. Axelrod, I.Y. Ge, W.F. Sheridan, and A.C. Flint Rapid warfarin reversal in the setting of intracranial hemorrhage: A comparison of plasma, recombinant activated factor VII, and prothrombin complex concentrate World Neurosurg. 81 2014 110 115
26. M. Cartmill, G. Dolan, J.L. Byrne, and P.O. Byrne Prothrombin complex concentrate for oral anticoagulant reversal in neurosurgical emergencies Br. J. Neurosurg. 14 2000 458 466
27. J.F. Guest, H.G. Watson, and S. Limaye Modeling the cost-effectiveness of prothrombin complex concentrate compared with fresh frozen plasma in emergency warfarin reversal in the United Kingdom Clin. Ther. 32 2010 2478 2493
28. L.A. Linkins, P.T. Choi, and J.D. Douketis Clinical impact of bleeding in patients taking oral anticoagulant therapy for venous thromboembolism: A meta-analysis Ann. Intern. Med. 139 2003 893 900
29. C.A. Leissinger, P.M. Blatt, W.K. Hoots, and B. Ewenstein Role of prothrombin complex concentrates in reversing warfarin anticoagulation: A review of the literature Am. J. Hematol. 83 2008 137 143
30. S.A. Voils, and B. Baird Systematic review: 3-factor versus 4-factor prothrombin complex concentrate for warfarin reversal: Does it matter? Thromb. Res. 130 2012 833 840
31. A.R. Parry-Jones, M. Di Napoli, J.N. Goldstein, F.H. Schreuder, S. Tetri, T. Tatlisumak, B. Yan, K.M. van Nieuwenhuizen, N. Dequatre-Ponchelle, M. Lee-Archer, S. Horstmann, D. Wilson, F. Pomero, L. Masotti, C. Lerpiniere, D.A. Godoy, A.S. Cohen, R. Houben, R. Al-Shahi Salman, P. Pennati, and et al. Reversal strategies for vitamin K antagonists in acute intracerebral hemorrhage Ann. Neurol. 2015 [Epub ahead of print]
32. D. Imberti, G. Barillari, C. Biasioli, M. Bianchi, L. Contino, R. Duce, and et al. Emergency reversal of anticoagulation with a three-factor prothrombin complex concentrate in patients with intracranial haemorrhage Blood Transfus. 9 2011 148 155
33. E. Lavenne-Pardonge, M.A. Itegwa, M. Kalaai, G. Klinkenberg, J.L. Loncke, K. Pelgrims, and et al. Emergency reversal of oral anticoagulation through PPSB-SD: The fastest procedure in Belgium Acta Anaesthesiol. Belg. 57 2006 121 125
34. D. Imberti, G. Barillari, C. Biasioli, M. Bianchi, L. Contino, R. Duce, and et al. Prothrombin complex concentrates for urgent anticoagulation reversal in patients with intracranial haemorrhage Pathophysiol. Haemost. Thromb. 36 5 2008 259 265
35. R.C. Shields, R.D. McBane, J.D. Kuiper, H. Li, and J.A. Heit Efficacy and safety of intravenous phytonadione (vitamin K1) in patients on long-term oral anticoagulant therapy Mayo Clin. Proc. 76 3 2001 Mar 260 266