Characterization of age-associated exhausted CD8+ T cells defined by increased expression of Tim-3 and PD-1

Aging Cell

Volumn 15, Issue 2, 2016, Pages 291-300

  Lee, Kyoo A ^a   Shin, Kwang Soo ^a   Kim, Ga Young ^b   Song, You Chan ^a   Bae, Eun Ah ^b   Kim, Il Kyu ^a   Koh, Choong Hyun ^a   Kang, Chang Yuil ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Aging; CD8+ T cells; PD 1; T cell exhaustion; Tim 3

Indexed keywords

HERMES ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 15 RECEPTOR; INTERLEUKIN 17 RECEPTOR; INTERLEUKIN 2 RECEPTOR BETA; INTERLEUKIN 7 RECEPTOR; L SELECTIN; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN; T CELL IMMUNOGLOBULIN MUCIN DOMAIN 3; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG; HAVCR2 PROTEIN, MOUSE; HEPATITIS A VIRUS CELLULAR RECEPTOR 2; PDCD1 PROTEIN, MOUSE;

AGED; AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; IMMUNE DYSREGULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE SUBPOPULATION; UPREGULATION; ANIMAL; BIOSYNTHESIS; IMMUNOLOGY; PATHOLOGY;

AGING; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; HEPATITIS A VIRUS CELLULAR RECEPTOR 2; MICE; PROGRAMMED CELL DEATH 1 RECEPTOR;

EID: 84960080908     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12435     Document Type: Article

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