Estradiol regulates human QT-interval: Acceleration of cardiac repolarization by enhanced KCNH2 membrane trafficking

European Heart Journal

Volumn 37, Issue 7, 2016, Pages 640-650

  Anneken, Lars ^a,b   Baumann, Stefan ^a,c   Vigneault, Patrick ^d   Biliczki, Peter ^a   Friedrich, Corinna ^e   Xiao, Ling ^d   Girmatsion, Zenawit ^a   Takac, Ina ^a   Brandes, Ralf P ^a   Kissler, Stefan ^a   Wiegratz, Inka ^a,f   Zumhagen, Sven ^e   Stallmeyer, Birgit ^e   Hohnloser, Stefan H ^a   Klingenheben, Thomas ^a,g   Schulze Bahr, Eric ^e   Nattel, Stanley ^d   Ehrlich, Joachim R ^a,h  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY HOSPITAL ERLANGEN   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d MONTREAL HEART INSTITUTE   (Canada)

^e UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^f Praxisgemeinschaft am Goetheplatz   (Germany)

^g Ambulante Herzkatheter Kooperation Bonn   (Germany)

^h ST JOSEFS HOSPITAL   (Germany)

Author keywords

Gender; Hormones; Ion channels; Long QT syndrome; Repolarization

Indexed keywords

CHAPERONE; CLOMIFENE CITRATE; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; GELDANAMYCIN; POTASSIUM CHANNEL; POTASSIUM CHANNEL KCNH2; PROGESTERONE; UNCLASSIFIED DRUG; BENZOQUINONE DERIVATIVE; CLOMIFENE; ENZYME INHIBITOR; FERTILITY PROMOTING AGENT; KCNH2 PROTEIN, HUMAN; MACROCYCLIC LACTAM; POTASSIUM CHANNEL HERG;

ACCELERATION; ARTICLE; CELL MEMBRANE; CELL MIGRATION; FEMALE; FEMALE INFERTILITY; HEART REPOLARIZATION; HORMONE DETERMINATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MENSTRUAL CYCLE; MISSENSE MUTATION; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; QTC INTERVAL; TRANSLATIONAL RESEARCH; ADULT; DRUG EFFECTS; ELECTROCARDIOGRAPHY; GENETICS; HEART MUSCLE CONDUCTION SYSTEM; HETEROZYGOTE; LONG QT SYNDROME; METABOLISM; PHYSIOLOGY; PREGNANCY; PREGNANCY COMPLICATION; PROSPECTIVE STUDY; PROTEIN TRANSPORT;

ADULT; BENZOQUINONES; CLOMIPHENE; ELECTROCARDIOGRAPHY; ENZYME INHIBITORS; ERG1 POTASSIUM CHANNEL; ESTRADIOL; FEMALE; FERTILITY AGENTS, FEMALE; HEALTHY VOLUNTEERS; HEART CONDUCTION SYSTEM; HETEROZYGOTE; HUMANS; INFERTILITY, FEMALE; LACTAMS, MACROCYCLIC; LONG QT SYNDROME; MENSTRUAL CYCLE; MUTATION, MISSENSE; PREGNANCY; PREGNANCY COMPLICATIONS, CARDIOVASCULAR; PROSPECTIVE STUDIES; PROTEIN TRANSPORT;

EID: 84960074791     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehv371     Document Type: Article

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