메뉴 건너뛰기




Volumn 101, Issue , 2016, Pages 75-85

Correlation between PD-L1 expression and outcome of NSCLC patients treated with anti-PD-1/PD-L1 agents: A meta-analysis

Author keywords

Nivolumab; NSCLC; PD 1; PD L1; Pembrolizumab

Indexed keywords

ATEZOLIZUMAB; AVELUMAB; DOCETAXEL; DURVALUMAB; NIVOLUMAB; PEMBROLIZUMAB; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; ANTINEOPLASTIC AGENT; CD274 PROTEIN, HUMAN; TAXOID;

EID: 84959865025     PISSN: 10408428     EISSN: 18790461     Source Type: Journal    
DOI: 10.1016/j.critrevonc.2016.03.007     Document Type: Review
Times cited : (119)

References (33)
  • 1
    • 84925831708 scopus 로고    scopus 로고
    • Risk of fatal pulmonary events in patients with advanced non-small-cell lung cancer treated with EGF receptor tyrosine kinase inhibitors: a comparative meta-analysis
    • Abdel-Rahman O., Elhalawani H. Risk of fatal pulmonary events in patients with advanced non-small-cell lung cancer treated with EGF receptor tyrosine kinase inhibitors: a comparative meta-analysis. Future Oncol. 2015, 11(7):1109-1122.
    • (2015) Future Oncol. , vol.11 , Issue.7 , pp. 1109-1122
    • Abdel-Rahman, O.1    Elhalawani, H.2
  • 2
    • 84942236061 scopus 로고    scopus 로고
    • Risk of cutaneous toxicities in patients with solid tumors treated with immune checkpoint inhibitors: a meta-analysis
    • Abdel-Rahman O., ElHalawani H., Fouad M. Risk of cutaneous toxicities in patients with solid tumors treated with immune checkpoint inhibitors: a meta-analysis. Future Oncol. 2015, 1-14.
    • (2015) Future Oncol. , pp. 1-14
    • Abdel-Rahman, O.1    ElHalawani, H.2    Fouad, M.3
  • 3
    • 84942294585 scopus 로고    scopus 로고
    • Risk of elevated transaminases in cancer patients treated with immune checkpoint inhibitors: a meta-analysis
    • Abdel-Rahman O., ElHalawani H., Fouad M. Risk of elevated transaminases in cancer patients treated with immune checkpoint inhibitors: a meta-analysis. Expert Opin. Drug Saf. 2015, 14(10):1507-1518.
    • (2015) Expert Opin. Drug Saf. , vol.14 , Issue.10 , pp. 1507-1518
    • Abdel-Rahman, O.1    ElHalawani, H.2    Fouad, M.3
  • 4
    • 84948171577 scopus 로고    scopus 로고
    • Risk of gastrointestinal complications in cancer patients treated with immune checkpoint inhibitors; a Meta-analysis
    • Abdel-Rahman O., ElHalawani H., Fouad M. Risk of gastrointestinal complications in cancer patients treated with immune checkpoint inhibitors; a Meta-analysis. Immunotherapy 2015.
    • (2015) Immunotherapy
    • Abdel-Rahman, O.1    ElHalawani, H.2    Fouad, M.3
  • 5
    • 84963946266 scopus 로고    scopus 로고
    • Risk of endocrine complications in cancer patients treated with immune check point inhibitors; a meta-analysis
    • Abdel-Rahman O., ElHalawani H., Fouad M. Risk of endocrine complications in cancer patients treated with immune check point inhibitors; a meta-analysis. Future Oncol. 2015.
    • (2015) Future Oncol.
    • Abdel-Rahman, O.1    ElHalawani, H.2    Fouad, M.3
  • 6
    • 84957436355 scopus 로고    scopus 로고
    • Risk of elevated transaminases in non small cell lung cancer (NSCLC) patients treated with erlotinib, gefitinib and afatinib; a Meta analysis
    • Abdel-Rahman O., Ahmed H., Elhalawani H. Risk of elevated transaminases in non small cell lung cancer (NSCLC) patients treated with erlotinib, gefitinib and afatinib; a Meta analysis. Expert Rev. Respir. Med. 2016, 10(2):223-234.
    • (2016) Expert Rev. Respir. Med. , vol.10 , Issue.2 , pp. 223-234
    • Abdel-Rahman, O.1    Ahmed, H.2    Elhalawani, H.3
  • 7
    • 84952638752 scopus 로고    scopus 로고
    • Immune checkpoints aberrations and gastric cancer; assessment of prognostic value and evaluation of therapeutic potentials
    • Abdel-Rahman O. Immune checkpoints aberrations and gastric cancer; assessment of prognostic value and evaluation of therapeutic potentials. Crit. Rev. Oncol. Hematol. 2015.
    • (2015) Crit. Rev. Oncol. Hematol.
    • Abdel-Rahman, O.1
  • 8
    • 84923072443 scopus 로고    scopus 로고
    • Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer
    • Azuma K., Ota K., Kawahara A., Hattori S., Iwama E., Harada T., et al. Association of PD-L1 overexpression with activating EGFR mutations in surgically resected nonsmall-cell lung cancer. Ann. Oncol. 2014, 25(10):1935-1940.
    • (2014) Ann. Oncol. , vol.25 , Issue.10 , pp. 1935-1940
    • Azuma, K.1    Ota, K.2    Kawahara, A.3    Hattori, S.4    Iwama, E.5    Harada, T.6
  • 9
    • 85009840975 scopus 로고    scopus 로고
    • Phase II, single-arm trial (BIRCH) of atezolizumab as first-line or subsequent therapy for locally advanced or metastatic PD-L1-selected non-small cell lung cancer (NSCLC)
    • (ELSEVIER SCI LTD THE BOULEVARD, LANGFORD, LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND)
    • Besse B., Johnson M., Jaenne P., Garassino M., Eberhardt W., Peters S., et al. Phase II, single-arm trial (BIRCH) of atezolizumab as first-line or subsequent therapy for locally advanced or metastatic PD-L1-selected non-small cell lung cancer (NSCLC). Eur. J. Cancer 2015, (ELSEVIER SCI LTD THE BOULEVARD, LANGFORD, LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND).
    • (2015) Eur. J. Cancer
    • Besse, B.1    Johnson, M.2    Jaenne, P.3    Garassino, M.4    Eberhardt, W.5    Peters, S.6
  • 10
    • 84944937210 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
    • Borghaei H., Paz-Ares L., Horn L., Spigel D.R., Steins M., Ready N.E., et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N. Engl. J. Med. 2015, 373(17):1627-1639.
    • (2015) N. Engl. J. Med. , vol.373 , Issue.17 , pp. 1627-1639
    • Borghaei, H.1    Paz-Ares, L.2    Horn, L.3    Spigel, D.R.4    Steins, M.5    Ready, N.E.6
  • 12
    • 84939227614 scopus 로고    scopus 로고
    • Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PD-L1): sensitivity analysis of trials in melanoma, lung and genitourinary cancers
    • Carbognin L., Pilotto S., Milella M., Vaccaro V., Brunelli M., Caliò A., et al. Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PD-L1): sensitivity analysis of trials in melanoma, lung and genitourinary cancers. PLoS One 2015, 10(6):e0130142.
    • (2015) PLoS One , vol.10 , Issue.6 , pp. e0130142
    • Carbognin, L.1    Pilotto, S.2    Milella, M.3    Vaccaro, V.4    Brunelli, M.5    Caliò, A.6
  • 14
    • 84937541453 scopus 로고    scopus 로고
    • Clinical correlation and frequency of programmed death ligand-1 (PD-L1) expression in EGFR-mutant and ALK-rearranged non-small cell lung cancer (NSCLC)
    • Gainor J.F., Sequist L.V., Shaw A.T., Azzoli C.G., Piotrowska Z., Huynh T., et al. Clinical correlation and frequency of programmed death ligand-1 (PD-L1) expression in EGFR-mutant and ALK-rearranged non-small cell lung cancer (NSCLC). ASCO Annual Meeting Proceedings 2015.
    • (2015) ASCO Annual Meeting Proceedings
    • Gainor, J.F.1    Sequist, L.V.2    Shaw, A.T.3    Azzoli, C.G.4    Piotrowska, Z.5    Huynh, T.6
  • 16
    • 84963963169 scopus 로고    scopus 로고
    • Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer
    • Gettinger S.N., Horn L., Gandhi L., Spigel D.R., Antonia S.J., Rizvi N.A., et al. Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer. J. Clin. Oncol. 2015: JCO 2014, 58:3708.
    • (2014) J. Clin. Oncol. 2015: JCO , vol.58 , pp. 3708
    • Gettinger, S.N.1    Horn, L.2    Gandhi, L.3    Spigel, D.R.4    Antonia, S.J.5    Rizvi, N.A.6
  • 17
    • 84947439090 scopus 로고    scopus 로고
    • First-line monotherapy with nivolumab (NIVO; anti-programmed death-1 [PD-1]) in advanced non-small cell lung cancer (NSCLC): Safety, efficacy and correlation of outcomes with PD-1 ligand (PD-L1) expression
    • Gettinger S.N., Hellmann M.D., Shepherd F.A., Antonia S.J., Brahmer J.R., Chow L.Q.M., et al. First-line monotherapy with nivolumab (NIVO; anti-programmed death-1 [PD-1]) in advanced non-small cell lung cancer (NSCLC): Safety, efficacy and correlation of outcomes with PD-1 ligand (PD-L1) expression. ASCO Annual Meeting Proceedings 2015.
    • (2015) ASCO Annual Meeting Proceedings
    • Gettinger, S.N.1    Hellmann, M.D.2    Shepherd, F.A.3    Antonia, S.J.4    Brahmer, J.R.5    Chow, L.Q.M.6
  • 18
    • 77950520452 scopus 로고    scopus 로고
    • Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data
    • Group NM-aC Adjuvant chemotherapy, with or without postoperative radiotherapy, in operable non-small-cell lung cancer: two meta-analyses of individual patient data. Lancet 2010, 375(9722):1267-1277.
    • (2010) Lancet , vol.375 , Issue.9722 , pp. 1267-1277
  • 19
    • 84944751040 scopus 로고    scopus 로고
    • Avelumab (MSB0010718C), an anti-PD-L1 antibody, in advanced NSCLC patients: a phase 1b, open-label expansion trial in patients progressing after platinum-based chemotherapy
    • Gulley J.L., Spigel D., Kelly K., Chandler J.C., Rajan A., Hassan R., et al. Avelumab (MSB0010718C), an anti-PD-L1 antibody, in advanced NSCLC patients: a phase 1b, open-label expansion trial in patients progressing after platinum-based chemotherapy. ASCO Annual Meeting Proceedings 2015.
    • (2015) ASCO Annual Meeting Proceedings
    • Gulley, J.L.1    Spigel, D.2    Kelly, K.3    Chandler, J.C.4    Rajan, A.5    Hassan, R.6
  • 20
    • 84950117835 scopus 로고    scopus 로고
    • Pembrolizumab versus docetaxel for previously treated PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
    • Herbst R.S., Baas P., Kim D.-W., Felip E., Pérez-Gracia J.L., Han J.-Y., et al. Pembrolizumab versus docetaxel for previously treated PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet 2016.
    • (2016) Lancet
    • Herbst, R.S.1    Baas, P.2    Kim, D.-W.3    Felip, E.4    Pérez-Gracia, J.L.5    Han, J.-Y.6
  • 21
    • 84964023141 scopus 로고    scopus 로고
    • High tumoral IFN gamma mRNA, PD-L1 protein, and combined IFN gamma mRNA/PD -L1 protein expression associates with response to durvalumab (anti-PD -L1) monotherapy in NSCLC patients
    • (ELSEVIER SCI LTD THE BOULEVARD, LANGFORD, LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND)
    • Higgs B., Robbins P., Blake-Haskins J., Zhu W., Morehouse C., Brohawn P., et al. High tumoral IFN gamma mRNA, PD-L1 protein, and combined IFN gamma mRNA/PD -L1 protein expression associates with response to durvalumab (anti-PD -L1) monotherapy in NSCLC patients. Eur. J. Cancer 2015, (ELSEVIER SCI LTD THE BOULEVARD, LANGFORD, LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND).
    • (2015) Eur. J. Cancer
    • Higgs, B.1    Robbins, P.2    Blake-Haskins, J.3    Zhu, W.4    Morehouse, C.5    Brohawn, P.6
  • 22
    • 84944714731 scopus 로고    scopus 로고
    • Clinical activity, safety and predictive biomarkers of the engineered antibody MPDL3280A (anti-PDL1) in non-small cell lung cancer (NSCLC): update from a phase Ia study
    • Horn L., Spigel D.R., Gettinger S.N., Antonia S.J., Gordon M.S., Herbst R.S., et al. Clinical activity, safety and predictive biomarkers of the engineered antibody MPDL3280A (anti-PDL1) in non-small cell lung cancer (NSCLC): update from a phase Ia study. ASCO Annual Meeting Proceedings 2015.
    • (2015) ASCO Annual Meeting Proceedings
    • Horn, L.1    Spigel, D.R.2    Gettinger, S.N.3    Antonia, S.J.4    Gordon, M.S.5    Herbst, R.S.6
  • 23
    • 84957453708 scopus 로고    scopus 로고
    • Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies
    • Ilie M., Long-Mira E., Bence C., Butori C., Lassalle S., Bouhlel L., et al. Comparative study of the PD-L1 status between surgically resected specimens and matched biopsies of NSCLC patients reveal major discordances: a potential issue for anti-PD-L1 therapeutic strategies. Ann. Oncol. 2015.
    • (2015) Ann. Oncol.
    • Ilie, M.1    Long-Mira, E.2    Bence, C.3    Butori, C.4    Lassalle, S.5    Bouhlel, L.6
  • 24
    • 84879579673 scopus 로고    scopus 로고
    • At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy
    • Intlekofer A.M., Thompson C.B. At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy. J. Leukoc. Biol. 2013, 94(1):25-39.
    • (2013) J. Leukoc. Biol. , vol.94 , Issue.1 , pp. 25-39
    • Intlekofer, A.M.1    Thompson, C.B.2
  • 26
    • 0029083342 scopus 로고
    • Randomized trials of radiotherapy alone versus combined chemotherapy and radiotherapy in stages IIIa and IIIb nonsmall cell lung cancer. A meta-analysis
    • Marino P., Preatoni A., Cantoni A. Randomized trials of radiotherapy alone versus combined chemotherapy and radiotherapy in stages IIIa and IIIb nonsmall cell lung cancer. A meta-analysis. Cancer 1995, 76(4):593-601.
    • (1995) Cancer , vol.76 , Issue.4 , pp. 593-601
    • Marino, P.1    Preatoni, A.2    Cantoni, A.3
  • 27
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
    • Moher D., Liberati A., Tetzlaff J., Altman D.G. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann. Intern. Med. 2009, 151(4):264-269.
    • (2009) Ann. Intern. Med. , vol.151 , Issue.4 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 28
    • 84924901863 scopus 로고    scopus 로고
    • Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial
    • Rizvi N.A., Mazières J., Planchard D., Stinchcombe T.E., Dy G.K., Antonia S.J., et al. Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol. 2015, 16(3):257-265.
    • (2015) Lancet Oncol. , vol.16 , Issue.3 , pp. 257-265
    • Rizvi, N.A.1    Mazières, J.2    Planchard, D.3    Stinchcombe, T.E.4    Dy, G.K.5    Antonia, S.J.6
  • 29
    • 84877611694 scopus 로고    scopus 로고
    • Methods for staging non-small cell lung cancer: diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines
    • e211S-e50S
    • Silvestri G.A., Gonzalez A.V., Jantz M.A., Margolis M.L., Gould M.K., Tanoue L.T., et al. Methods for staging non-small cell lung cancer: diagnosis and management of lung cancer: American College of Chest Physicians evidence-based clinical practice guidelines. Chest J. 2013, 143(Suppl 5). e211S-e50S.
    • (2013) Chest J. , vol.143
    • Silvestri, G.A.1    Gonzalez, A.V.2    Jantz, M.A.3    Margolis, M.L.4    Gould, M.K.5    Tanoue, L.T.6
  • 30
    • 84904024273 scopus 로고    scopus 로고
    • Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy
    • Taube J.M., Klein A., Brahmer J.R., Xu H., Pan X., Kim J.H., et al. Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy. Clin. Cancer Res. 2014, 20(19):5064-5074.
    • (2014) Clin. Cancer Res. , vol.20 , Issue.19 , pp. 5064-5074
    • Taube, J.M.1    Klein, A.2    Brahmer, J.R.3    Xu, H.4    Pan, X.5    Kim, J.H.6
  • 31
    • 53149091690 scopus 로고    scopus 로고
    • Lung cancer occurrence in never-smokers: an analysis of 13 cohorts and 22 cancer registry studies
    • Thun M.J., Hannan L.M., Adams-Campbell L.L., Boffetta P., Buring J.E., Feskanich D., et al. Lung cancer occurrence in never-smokers: an analysis of 13 cohorts and 22 cancer registry studies. PLoS Med. 2008, 5(9):e185.
    • (2008) PLoS Med. , vol.5 , Issue.9 , pp. e185
    • Thun, M.J.1    Hannan, L.M.2    Adams-Campbell, L.L.3    Boffetta, P.4    Buring, J.E.5    Feskanich, D.6
  • 32
    • 84969542128 scopus 로고    scopus 로고
    • Atezolizumab monotherapy vs docetaxel in 2L/3L non-small cell lung cancer: primary analyses for efficacy, safety and predictive biomarkers from a randomized phase II study (POPLAR)
    • (ELSEVIER SCI LTD THE BOULEVARD, LANGFORD, LANE, KIDLINGTON, OXFORD O 1GB, OXON, ENGLAND)
    • Vansteenkiste J., Fehrenbacher L., Spira A., Mazieres J., Park K., Smith D., et al. Atezolizumab monotherapy vs docetaxel in 2L/3L non-small cell lung cancer: primary analyses for efficacy, safety and predictive biomarkers from a randomized phase II study (POPLAR). Eur. J. Cancer 2015, X5. (ELSEVIER SCI LTD THE BOULEVARD, LANGFORD, LANE, KIDLINGTON, OXFORD O 1GB, OXON, ENGLAND).
    • (2015) Eur. J. Cancer , pp. X5
    • Vansteenkiste, J.1    Fehrenbacher, L.2    Spira, A.3    Mazieres, J.4    Park, K.5    Smith, D.6
  • 33
    • 84891373595 scopus 로고    scopus 로고
    • Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial
    • Westin J.R., Chu F., Zhang M., Fayad L.E., Kwak L.W., Fowler N., et al. Safety and activity of PD1 blockade by pidilizumab in combination with rituximab in patients with relapsed follicular lymphoma: a single group, open-label, phase 2 trial. Lancet Oncol. 2014, 15(1):69-77.
    • (2014) Lancet Oncol. , vol.15 , Issue.1 , pp. 69-77
    • Westin, J.R.1    Chu, F.2    Zhang, M.3    Fayad, L.E.4    Kwak, L.W.5    Fowler, N.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.