Surface-modified biodegradable nanoparticles' impact on cytotoxicity and inflammation response on a co-culture of lung epithelial cells and human-like macrophages

Journal of Biomedical Nanotechnology

Volumn 12, Issue 1, 2016, Pages 135-146

  Grabowski, Nadège ^a,b   Hillaireau, Hervé ^a,b   Vergnaud Gauduchon, Juliette ^a,b   Nicolas, Valérie ^c   Tsapis, Nicolas ^a,b   Kerdine Römer, Saadia ^d   Fattal, Elias ^a,b  

^a UNIVERSITÉ PARIS SACLAY   (France)

^b CNRS   (France)

^c IPSIT   (France)

^d INSERM   (France)

Author keywords

Co culture; Epithelial cell; Macrophage; Nanoparticles

Indexed keywords

BIODEGRADABLE POLYMERS; BIOLOGICAL ORGANS; CELL DEATH; CYTOLOGY; MACROPHAGES; NANOPARTICLES; PHYSIOLOGY; POLYMERS; TOXICITY;

ALVEOLAR EPITHELIAL CELLS; BIODEGRADABLE NANOPARTICLE; CO-CULTURES; CONFOCAL LASER SCANNING MICROSCOPY; EPITHELIAL CELLS; INFLAMMATORY RESPONSE; POLY-LACTIDE-CO-GLYCOLIDE; STABILIZED NANOPARTICLES;

CELLS;

CHITOSAN; INTERLEUKIN 10; INTERLEUKIN 12P70; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; NANOPARTICLE; POLOXAMER; POLYGLACTIN; STABILIZING AGENT; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; LACTIC ACID; NANOCAPSULE; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL SUBPOPULATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE; HUMAN; HUMAN CELL; IMMUNOPHENOTYPING; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS MACROPHAGE; MACROPHAGE; PARTICLE SIZE; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL; BIODEGRADABLE IMPLANT; CELL LINE; CHEMICALLY INDUCED; CHEMISTRY; COCULTURE; DRUG EFFECTS; EPITHELIUM CELL; IMMUNOLOGY; MACROPHAGE ACTIVATION; PATHOLOGY; SURFACE PROPERTY;

ABSORBABLE IMPLANTS; CELL LINE; COCULTURE TECHNIQUES; CYTOKINES; EPITHELIAL CELLS; HUMANS; INFLAMMATION; LACTIC ACID; MACROPHAGE ACTIVATION; MACROPHAGES; NANOCAPSULES; POLYGLYCOLIC ACID; SURFACE PROPERTIES;

EID: 84959540797     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2016.2126     Document Type: Article

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