Effects of enzyme replacement therapy on immune function in ADA deficiency patient

Clinical Immunology

Volumn 161, Issue 2, 2015, Pages 391-393

  Nakazawa, Yumiko ^a   Kawai, Toshinao ^a   Uchiyama, Toru ^a   Goto, Fumihiro ^a   Watanabe, Nobuyuki ^a   Maekawa, Takanobu ^b   Ishiguro, Akira ^b   Okuyama, Torayuki ^b   Otsu, Makoto ^c   Yamada, Masafumi ^e   Hershfield, Michael S ^d   Ariga, Tadashi ^e   Onodera, Masafumi ^a  

^a NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^b NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e HOKKAIDO UNIVERSITY   (Japan)

Author keywords

Adenosine deaminase deficiency; Enzyme replacement therapy; Immune reconstitution; PEG ADA; Severe combined immunodeficiency; Stem cell gene therapy

Indexed keywords

ADENOSINE; ADENOSINE DEAMINASE; B CELL ACTIVATING FACTOR RECEPTOR; CD38 ANTIGEN; CD45RA ANTIGEN; CD5 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; DEOXYADENOSINE; IMMUNOGLOBULIN; IMMUNOGLOBULIN D; IMMUNOGLOBULIN M; PEGADEMASE;

ADENOSINE DEAMINASE DEFICIENCY; ADOLESCENT; ANALYTICAL EQUIPMENT; CASE REPORT; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNODEFICIENCY; CHILD; CLONAL VARIATION; ENZYME ACTIVITY; ENZYME REPLACEMENT; ERYTHROCYTE; FAILURE TO THRIVE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GASTROINTESTINAL SYMPTOM; HUMAN; HUMORAL IMMUNE DEFICIENCY; IMMUNE RESPONSE; LETTER; LOSS OF APPETITE; LYMPHOCYTE COUNT; MEMORY CELL; OUTCOME ASSESSMENT; PNEUMONIA; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; STEM CELL GENE THERAPY; THERAPY EFFECT; AGAMMAGLOBULINEMIA; B LYMPHOCYTE; BLOOD; DEFICIENCY; DRUG EFFECTS; ENZYMOLOGY; FLOW CYTOMETRY; IMMUNOLOGY; METABOLISM; PROCEDURES; SEVERE COMBINED IMMUNODEFICIENCY; T LYMPHOCYTE; TREATMENT OUTCOME;

ADENOSINE DEAMINASE; ADOLESCENT; AGAMMAGLOBULINEMIA; B-LYMPHOCYTES; ENZYME REPLACEMENT THERAPY; FEMALE; FLOW CYTOMETRY; HUMANS; LYMPHOCYTE COUNT; SEVERE COMBINED IMMUNODEFICIENCY; T-LYMPHOCYTES; TREATMENT OUTCOME;

EID: 84959528016     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2015.06.011     Document Type: Letter

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