History of medicine: Stroke and t-PA-triggering new paradigms of care

New England Journal of Medicine

Volumn 374, Issue 9, 2016, Pages 809-811

  Snow, S J ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

TISSUE PLASMINOGEN ACTIVATOR; FIBRINOLYTIC AGENT;

BRAIN HEMORRHAGE; CAROTID ARTERY THROMBOSIS; CEREBROVASCULAR ACCIDENT; DRUG EFFICACY; HEALTH CARE; HEALTH CARE ACCESS; HEALTH CARE POLICY; HEALTH CARE SYSTEM; HISTORY OF MEDICINE; HUMAN; PRIORITY JOURNAL; REVIEW; RISK BENEFIT ANALYSIS; TRANSIENT ISCHEMIC ATTACK; BRAIN ISCHEMIA; CEREBROVASCULAR DISEASE; HISTORY; STROKE; TIME TO TREATMENT;

BRAIN ISCHEMIA; CEREBROVASCULAR DISORDERS; FIBRINOLYTIC AGENTS; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; STROKE; TIME-TO-TREATMENT; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84959515986     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMp1514696     Document Type: Review

References (5)

1. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. N Engl J Med 1995; 333:1581-8.
2. Laureno R. Raymond Adams: a life of mind and muscle. Oxford, England: Oxford University Press, 2009.
3. Wright IS, McDevitt E. Cerebral vascular diseases: their significance, diagnosis and present treatment, including the selective use of anticoagulant substances. Ann Intern Med 1954;41:682-98.
4. Hoffman JR. Should physicians give tPA to patients with acute ischemic stroke? Against: and just what is the emperor of stroke wearing? West J Med 2000; 173: 149-50.
5. Audebert HJ, Sobesky J. Stroke: 'time is brain' after stroke, regardless of age and severity. Nat Rev Neurol 2014; 10: 675-6.