Effect of Pre-Hospital Ticagrelor during the First 24 h after Primary Percutaneous Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction the ATLANTIC-H24 Analysis

JACC: Cardiovascular Interventions

Volumn 9, Issue 7, 2016, Pages 646-656

  Montalescot, Gilles ^a   Van 'T Hof, Arnoud W ^b   Bolognese, Leonardo ^c   Cantor, Warren J ^d,t   Cequier, Angel ^e   Chettibi, Mohamed ^f   Collet, Jean Philippe ^a   Goodman, Shaun G ^g   Hammett, Christopher J ^h,t   Huber, Kurt ⁱ   Janzon, Magnus ^j   Lapostolle, Frédéric ^k   Lassen, Jens Flensted ^l   Licour, Muriel ^m   Merkely, Béla ⁿ   Salhi, Néjoua ^m   Silvain, Johanne ^a   Storey, Robert F ^o   Ten Berg, Jurriën M ^p   Tsatsaris, Anne ^m   Zeymer, Uwe ^q   Vicaut, Eric ^r   Hamm, Christian W ^s,t   Bougherbal, Rachid ^t   Bouafia, Mohamed Tahar ^t   Nibouche, Djamaleddine ^t   Moklati, Abdelkader ^t   Benalia, Ahmed ^t   Kaid, Omar ^t   Krim, Messaad ^t   Garrahy, Paul ^t   Jayasinghe, Rohan ^t   Rashford, Stephen ^t   Neunteufl, Thomas ^t   Brussee, Helmut ^t   Alber, Hannes ^t   Weidinger, Franz ^t   Brunner, Michael ^t   Sipoetz, Johann ^t   Prause, Gerhard ^t   Baubin, Michael ^t   Sebald, Dieter ^t   Vijayaraghavan, Ram ^t   Bata, Iqbal ^t   Lavoie, Andrea ^t   Ravkilde, Jan ^t   Jensen, Lisette Okkels ^t   Christensen, Alf Møl ^t   Toftegaard, Marianne ^t   Köhler, Dennis ^t   Ducrocq, Gregory ^t   Danchin, Nicolas ^t   Henry, Patrick ^t   Livarek, Bernard ^t   Berthier, Romain ^t   Hovasse, Thomas ^t   Garot, Philippe ^t   Payot, Laurent ^t   Benamer, Hakim ^t   Esteve, Jean Baptiste ^t   Elhadad, Simon ^t   Teiger, Emmanuel ^t   Bonnet, Jean Louis ^t   Paganelli, Franck ^t   Cottin, Yves ^t   Schiele, François ^t   Thuaire, Christophe ^t   Cayla, Guillaume ^t   Coste, Pierre ^t   Ohlmann, Patrick ^t   Cudraz, Eric Bonnefoy ^t   Lantelme, Pierre ^t   Perret, Thibault ^t   Tron, Christophe ^t   De Labriolle, Axel ^t   Aptecar, Edouardo ^t   Beliard, Olivier ^t   Varenne, Olivier ^t   El Mahmoud, Rami ^t   Filippi Codaccioni, Emmanuelle ^t   Angoulvant, Denis ^t   Peycher, Patrick ^t   Poitrineau, Olivier ^t   Tabone, Xavier ^t   Ecollan, Patrick ^t   Broche, Claire ^t   Lambert, Yves ^t   Briole, Nicolas ^t   Beruben, Arielle ^t   Porcher, Nicolas ^t   Auffray, Jean Pierre ^t   Freysz, Marc ^t   Depardieu, Franck ^t   Poubel, David ^t   De La Cousaye, Jean Emmanuel ^t   Bartier, Jean Claude ^t   Jardel, Benoît ^t   Boulanger, Bertrand ^t   Labourel, Hervé ^t   Soulat, Louis Christophe ^t   Julie, Véronique ^t   Thicoipe, Michel ^t   Capel, Olivier ^t   Stibbe, Olivier ^t   Carli, Pierre ^t   Tazarourte, Karim ^t   Alcouffe, Fabrice ^t   Aboucaya, David ^t   Aubert, Gaële ^t   Kierzek, Gérald ^t   Cahun Giraud, Séverine ^t   Dengler, Thomas ^t   Prondzinsky, Roland ^t   Biever, Paul Marc ^t   Schäfer, Andreas ^t   Seyfarth, Melchior ^t   Lemke, Bernd ^t   Werner, Gerald ^t   Nef, Holger ^t   Steiger, Holger ^t   Leschke, Matthias ^t   Münzel, Thomas ^t   Dell Orto, Marco Campo ^t   Loges, Christian ^t   Schinke, Monika ^t   Koberne, Frank ^t   Reiffen, Hans Peter ^t   Tiroch, Klaus ^t   Wierich, Dirk ^t   Kneussel, Michael ^t   Little, Simon ^t   Sauer, Hartmut ^t   Laufenberg Feldmann, Rita ^t   Ungi, Imre ^t   Horváth, Iván ^t   Édes, István ^t   Mártai, István ^t   Berti, Sergio ^t   Chiarella, Francesco ^t   Calabria, Paolo ^t   Fineschi, Massimo ^t   Galvani, Marcello ^t   Valgimigli, Marco ^t   Moretti, Luciano ^t   Tespili, Maurizio ^t   Mandó, Massimo ^t   Bermano, Francesco ^t   Biagioni, Robusto ^t   Fabbri, Andrea ^t   Ricciardelli, Adelina ^t   Petroni, Maria Romana ^t   Vatteroni, Umberto Roberto ^t   Palumbo, Francesco ^t   Willems, Frank F ^t   Al Mafragi, Amar ^t   Heestermans, Ton A A C M ^t   Van Eck, Martijn J ^t   Heutz, Wim M J M ^t   Meppelder, H H ^t   Jong, Anika Roukema De ^t   Van De Pas, Harm ^t   Fillat, Ángel Cequier ^t   Tenas, Manel Sabaté ^t   Ferrer, Josepa Mauri ^t   Peñaranda, Antoni Serra ^t   Ferrer, Joan Ángel ^t   Del Blanco, Bruno García ^t   Guardiola, Faustino Miranda ^t   Ruiz Nodar, Juan Miguel ^t   Romo, Andrés Íñiguez ^t   González, Nicolás Vázquez ^t   Nouche, Ramiro Trillo ^t   De La Llera, Luis Díaz ^t   Hernández García, José María ^t   Rivero Crespo, Fernando ^t   Hernández, Felipe Hernández ^t   Zamorano Gómez, José Luis ^t   Fárega, Xavier Jiménez ^t   Fernández, Gilberto Alonso ^t   Toboso, José Luis ^t   Carrasco, Mercedes ^t   Barreiro, Victoria ^t   Iglesias Vázquez, José Antonio ^t   Montero, María Del Mar Ruiz ^t   Ortiz, Fernando Rosell ^t   Escudero, Guillermo Garcia ^t   Ingelmo, Vicente Sánchez Brunete ^t   García, Antonio Lara ^t   Oldgren, Jonas ^t   Calais, Fredrik ^t   Kastberg, Robert ^t   Bergsten, Per Adolf ^t   Blomberg, Hans ^t   Thörn, Kristian ^t   Skoog, Gunnar ^t   Zaman, Azfar ^t   Gerber, Robert ^t   Ryding, Alisdair ^t   Spence, Mark ^t   Swanson, Neil ^t   Been, Martin ^t   Grosser, Konrad ^t   Schofield, Peter ^t   Mackin, David ^t   Fell, Paul ^t   Quinn, Tom ^t   Foster, Teresa ^t   McManus, David ^t   Carson, Andy ^t   more..

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b ISALA HOSPITAL   (Netherlands)

^c Azienda Ospedaliera Arezzo   (Italy)

^d UNIVERSITY OF TORONTO   (Canada)

^e HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^f Centre Hospitalo Universitaire Frantz Fanon   (Algeria)

^g ST MICHAEL'S HOSPITAL   (Canada)

^h ROYAL BRISBANE AND WOMEN'S HOSPITAL   (Australia)

ⁱ WILHELMINEN HOSPITAL   (Austria)

^j LINKÖPING UNIVERSITY   (Sweden)

^k AVICENNE HOSPITAL   (France)

^l AARHUS UNIVERSITY HOSPITAL   (Denmark)

^m ASTRAZENECA   (United Kingdom)

ⁿ SEMMELWEIS UNIVERSITY   (Hungary)

^o UNIVERSITY OF SHEFFIELD   (United Kingdom)

^p ST ANTONIUS HOSPITAL   (Netherlands)

^q KLINIKUM LUDWIGSHAFEN   (Germany)

^r UNIVERSITÉ PARIS DESCARTES   (France)

^s KERCKHOFF HEART CENTER   (Germany)

^t NONE

more..

Author keywords

myocardial infarction; platelets; reperfusion; stents; thrombosis

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; FIBRINOGEN RECEPTOR ANTAGONIST; TICAGRELOR; ADENOSINE; ANTITHROMBOCYTIC AGENT;

ADULT; ARTICLE; BLEEDING; CARDIOGENIC SHOCK; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; CORONARY REPERFUSION; DOUBLE BLIND PROCEDURE; DRUG ELUTING STENT; FEMALE; HEART ARREST; HEART FAILURE; HEART INFARCTION; HEART MUSCLE REVASCULARIZATION; HUMAN; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PATIENT SAFETY; PERCUTANEOUS CORONARY INTERVENTION; PLATELET REACTIVITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ST SEGMENT ELEVATION; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STENT THROMBOSIS; ADVERSE EFFECTS; AGED; AMBULANCE; ANALOGS AND DERIVATIVES; BLOOD; BLOOD CLOTTING PARAMETERS; CLINICAL TRIAL; COMPARATIVE STUDY; CORONARY THROMBOSIS; DIAGNOSTIC IMAGING; DRUG EFFECTS; EMERGENCY HEALTH SERVICE; MIDDLE AGED; MORTALITY; MULTICENTER STUDY; PROCEDURES; RECURRENT DISEASE; ST ELEVATION MYOCARDIAL INFARCTION; THROMBOCYTE AGGREGATION; TIME FACTOR; TIME TO TREATMENT; TREATMENT OUTCOME;

ADENOSINE; ADULT; AGED; AMBULANCES; CORONARY THROMBOSIS; DOUBLE-BLIND METHOD; EMERGENCY MEDICAL SERVICES; FEMALE; HUMANS; MALE; MIDDLE AGED; PERCUTANEOUS CORONARY INTERVENTION; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; RECURRENCE; ST ELEVATION MYOCARDIAL INFARCTION; TIME FACTORS; TIME-TO-TREATMENT; TREATMENT OUTCOME;

EID: 84959464492     PISSN: 19368798     EISSN: 18767605     Source Type: Journal    
DOI: 10.1016/j.jcin.2015.12.024     Document Type: Article

References (17)

1. G. Montalescot, A.W. van 't Hof, F. Lapostolle, and et al. Prehospital ticagrelor in ST-segment elevation myocardial infarction N Engl J Med 371 2014 1016 1027
2. G. Montalescot, and A.W. van 't Hof Prehospital ticagrelor in ST-segment elevation myocardial infarction (letter) N Engl J Med 371 2014 2339
3. G. Montalescot, J.F. Lassen, C.W. Hamm, and et al. Ambulance or in-catheterization laboratory administration of ticagrelor for primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: rationale and design of the randomized, double-blind Administration of Ticagrelor in the cath Lab or in the Ambulance for New ST elevation myocardial Infarction to open the Coronary artery (ATLANTIC) study Am Heart J 165 2013 515 522
4. M. Valgimigli, M. Tebaldi, G. Campo, and et al. Prasugrel versus tirofiban bolus with or without short post-bolus infusion with or without concomitant prasugrel administration in patients with myocardial infarction undergoing coronary stenting: the FABOLUS PRO (Facilitation through Aggrastat By drOpping or shortening Infusion Line in patients with ST-segment elevation myocardial infarction compared to or on top of PRasugrel given at loading dOse) trial J Am Coll Cardiol Intv 5 2012 268 277
5. S. Koul, P. Andell, A. Martinsson, and et al. A pharmacodynamic comparison of 5 anti-platelet protocols in patients with ST-elevation myocardial infarction undergoing primary PCI BMC Cardiovasc Disord 14 2014 189
6. D.S. Wald, J.K. Morris, and N.J. Wald Preventive angioplasty in myocardial infarction N Engl J Med 370 2014 283
7. M.S. Sabatine, C.P. Cannon, C.M. Gibson, and et al. Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation N Engl J Med 352 2005 1179 1189
8. B.M. Scirica, M.S. Sabatine, D.A. Morrow, and et al. The role of clopidogrel in early and sustained arterial patency after fibrinolysis for ST-segment elevation myocardial infarction: the ECG CLARITY-TIMI 28 Study J Am Coll Cardiol 48 2006 37 42
9. G.W. Stone, B. Witzenbichler, G. Guagliumi, and et al. Bivalirudin during primary PCI in acute myocardial infarction N Engl J Med 358 2008 2218 2230
10. D.L. Bhatt, A.M. Lincoff, C.M. Gibson, and et al. Intravenous platelet blockade with cangrelor during PCI N Engl J Med 361 2009 2330 2341
11. D.L. Bhatt, G.W. Stone, K.W. Mahaffey, and et al. Effect of platelet inhibition with cangrelor during PCI on ischemic events N Engl J Med 368 2013 1303 1313
12. G. Montalescot, P. Barragan, O. Wittenberg, and et al. Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction N Engl J Med 344 2001 1895 1903
13. G. De Luca, E. Navarese, and P. Marino Risk profile and benefits from Gp IIb-IIIa inhibitors among patients with ST-segment elevation myocardial infarction treated with primary angioplasty: a meta-regression analysis of randomized trials Eur Heart J 30 2009 2705 2713
14. K. Huber, D.R. Holmes Jr., A.W. van 't Hof, and et al. Use of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention: insights from the APEX-AMI trial Eur Heart J 31 2010 1708 1716
15. G.W. Stone, C.L. Grines, D.A. Cox, and et al. Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction N Engl J Med 346 2002 957 966
16. A.W. van 't Hof, J.M. ten Berg, T. Heestermans, and et al. Prehospital initiation of tirofiban in patients with ST-elevation myocardial infarction undergoing primary angioplasty (On-TIME 2): a multicentre, double-blind, randomised controlled trial Lancet 372 2008 537 546
17. G. Parodi, I. Xanthopoulou, B. Bellandi, and et al. Ticagrelor crushed tablets administration in STEMI patients: the MOJITO study J Am Coll Cardiol 65 2015 511 512