The effect of genetic test-based risk information on behavioral outcomes: A critical examination of failed trials and a call to action

American Journal of Medical Genetics, Part A

Volumn 167, Issue 12, 2015, Pages 2913-2915

  Austin, Jehannine ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Behavioral change; Behavioral economics; Biases; Cancer; Complex disorders; Diabetes; Genetic counseling; Genetic risk; Heart disease; Heuristics; Lifestyle modification

Indexed keywords

ARTICLE; BEHAVIOR CHANGE; CANCER RISK; DIABETES MELLITUS; DIET RESTRICTION; EMOTION; EXERCISE; FEEDING BEHAVIOR; GENETIC COUNSELING; GENETIC RISK; GENETIC SCREENING; HEALTH BEHAVIOR; HEART DISEASE; HIGH RISK BEHAVIOR; LIFESTYLE MODIFICATION; NEOPLASM; PRIORITY JOURNAL; PSYCHOTHERAPY; RISK REDUCTION; SMOKING CESSATION; ATTITUDE TO HEALTH; CLINICAL TRIAL (TOPIC); HUMAN; PROCEDURES; PSYCHOLOGY;

ATTITUDE TO HEALTH; CLINICAL TRIALS AS TOPIC; EMOTIONS; GENETIC COUNSELING; GENETIC TESTING; HUMANS;

EID: 84959338941     PISSN: 15524825     EISSN: 15524833     Source Type: Journal    
DOI: 10.1002/ajmg.a.37289     Document Type: Article

References (17)

1. Blumenthal-Barby JS, McGuire AL, Ubel PA. 2014. Why information alone is not enough: Behavioral economics and the future of genomic medicine. Ann Int Med 161:605-606.
2. Boeldt DL, Schork NJ, Topol EJ, Bloss CS. 2015. Influence of individual differences in disease perception on consumer response to direct-to-consumer genomic testing. Clin Genet 87:225-232.
3. Edwards A, Gray J, Clarke AJ, Dundon J, Elwyn G, Gaff CL, Hood K, Iredale R, Sivell S, Shaw C, Thornton H. 2008. Interventions to improve risk communication in clinical genetics: Systematic review. Patient Educ Couns 71:4-25.
4. Gigerenzer G, Selten R. 2002. Bounded rationality. Cambridge, MA: MIT Press.
5. Grant RW, O'Brien KE, Waxler JL, Vassy JL, Delahanty LM, Bissett LG, Green RC, Stember KG, Guiducci C, Park ER, Florez JC, Meigs JB. 2013. Personalized genetic risk counseling to motivate diabetes prevention: A randomized trial. Diabetes Care 36:13-19.
6. Inglis A, Koehn D, McGillivray B, Stewart SE, Austin J. 2015. Evaluating a unique, specialist psychiatric genetic counseling clinic: Uptake and impact. Clin Genet 87:218-224.
7. Jorgensen T, Jacobsen RK, Toft U, Aadahl M, Glumer C, Pisinger C. 2014. Effect of screening and lifestyle counselling on incidence of ischaemic heart disease in general population: Inter99 randomised trial. BMJ 348:g3617-g3617.
8. Kahneman D. 2011. Thinking, fast and slow. Canada: Doubleday.
9. Marteau T, French D, Griffin S. 2010. Effects of communicating DNA-based disease risk estimates on risk-reducing behaviours. Cochrane Database Syst Rev 6:CD007275.
10. McCarthy-Veach P, Bartels DM, LeRoy BS. 2007. Coming full circle: A reciprocal-engagement model of genetic counseling practice. J Genet Couns 16:713-728.
11. Michie S, van Stralen MM, West R. 2011. The behaviour change wheel: A new method for characterising and designing behaviour change interventions. Implement Sci 6:42.
12. Miller WR, Rollnick S. 2009. Ten things that motivational interviewing is not. Behav Cogn Psychoth 37:129-140.
13. Resta R, Biesecker BB, Bennett RL, Blum S, Estabrooks HS, Strecker MN, Williams JL. 2006. A new definition of genetic counseling: National Society of Genetic Counselors' task force report. J Genet Couns 15:77-83.
14. Rutherford S, Zhang X, Atzinger C, Ruschman J, Myers MF. 2014. Medical management adherence as an outcome of genetic counseling in a pediatric setting. GiM 16:157-163.
15. Slovic P, Finucane ML, Peters E, MacGregor DG. 2004. Risk as analysis and risk as feelings: Some thoughts about affect, reason, risk, and rationality. Risk Anal 24:311-322.
16. Walter FM, Emery J, Braithwaite D, Marteau TM. 2004. Lay understanding of familial risk of common chronic diseases: A systematic review and synthesis of qualitative research. Ann Fam Med 2:583-594.
17. Weinberg DS, Myers RE, Keenan E, Ruth K, Sifri R, Ziring B, Ross E, Manne S. 2014. Genetic and environmental risk assessment and colorectal cancer screening in an average-risk population. Ann Int Med 161:537-545.