Advances in the development and validation of test methods in the united states

Toxicological Research

Volumn 32, Issue 1, 2016, Pages 9-14

  Casey, Warren M ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Alternative; HTS; Tox21; Toxicity; US; Validation

Indexed keywords

EID: 84959274248     PISSN: 19768257     EISSN: 22342753     Source Type: Journal    
DOI: 10.5487/TR.2016.32.1.009     Document Type: Article

References (8)

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3. National Academy of Sciences. (2007) Board on environmental studies and toxicology. Toxicity testing in the 21st century: a vision and a strategy. The National Academies Press, Washington DC.
4. Browne, P., Judson, R.S., Casey, W.M., Kleinstreuer, N.C. and Thomas, R. (2015) Screening chemicals for estrogen receptor bioactivity using a computational model. Environ. Sci. Technol., 49, 8804-8814.
5. Judson, R.S., Magpantay, F.M., Chickarmane, V., Haskell, C., Tania, N., Taylor, J., Xia, M., Huang, R., Rotroff, D.M., Filer, D.L., Houck, K.A., Martin, M.T., Sipes, N., Richard, A.M., Mansouri, K., Setzer, R.W., Knudsen, T.B., Croffon, K.M. and Thomas, R.S. (2015) Integrated model of chemical perturbations of a biological pathway using 18 in vitro high throughput screening assays for the estrogen receptor. Toxicol. Sci., 148, 137-154.
6. Kleinstreuer, N.C., Ceger, P.C., Allen, D.G., Strickland, J., Chang, X., Hamm, J.T. and Casey, W.M. (2015) A curated database of rodent uterotrophic bioactivity. Environ. Health Perspect., doi:10.1289/ehp.1510183.
7. Dix, D.J., Houck, K.A., Martin, M.T., Richard, A.M., Setzer, R.W. and Kavlock, R.J. (2007) The toxcast program for prioritizing toxicity testing of environmental chemicals. Toxicol. Sci., 95, 5-12.
8. Rotroff, D.M., Dix, D.J., Houck, K.A., Knudsen, T.B., Martin, M.T., McLaurin, K.W., Reif, D.M., Crofton, K.M., Singh, A.V., Xia, M., Huang, R. and Judson, R.S. (2013) Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals. Environ. Health Perspect., 121, 7-14.