Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity

Cell Host and Microbe

Volumn 19, Issue 3, 2016, Pages 361-374

  Sterkel, Alan K ^a   Lorenzini, Jenna L ^a   Fites, J Scott ^a   Subramanian Vignesh, Kavitha ^b   Sullivan, Thomas D ^a   Wuthrich, Marcel ^a   Brandhorst, Tristan ^a   Hernandez Santos, Nydiaris ^a   Deepe, George S ^b   Klein, Bruce S ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

DppIV; fungal; macrophages; neutrophils; TipDCs

Indexed keywords

AMINOPEPTIDASE; BETA CHEMOKINE; CHEMOKINE RECEPTOR CCR2; DIPEPTIDYL PEPTIDASE; DIPEPTIDYL PEPTIDASE IVA; ECTOPEPTIDASE CD26; FUNGAL ENZYME; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PEPTIDASE; REACTIVE OXYGEN METABOLITE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; CHEMOKINE; VIRULENCE FACTOR;

AJELLOMYCES DERMATITIDIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DPPIVA GENE; EFFECTOR CELL; FUNGAL GENE; FUNGAL MIMICRY; FUNGAL VIRULENCE; GENE EXPRESSION; GENE SILENCING; IMMUNOREGULATION; INNATE IMMUNITY; LEUKOCYTE; MOLECULAR MIMICRY; MONOCYTE; MOUSE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; SYSTEMIC MYCOSIS; ANIMAL; BIOLOGICAL MIMICRY; BLASTOMYCES; DRUG EFFECTS; ENZYMOLOGY; GENETICS; IMMUNE EVASION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MACROPHAGE; METABOLISM; MICROBIAL VIABILITY; PATHOGENICITY; PHAGOCYTOSIS; SEQUENCE HOMOLOGY;

AMINOPEPTIDASES; ANIMALS; BIOLOGICAL MIMICRY; BLASTOMYCES; CHEMOKINES; DIPEPTIDYL-PEPTIDASES AND TRIPEPTIDYL-PEPTIDASES; GENE SILENCING; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; IMMUNE EVASION; IMMUNE TOLERANCE; IMMUNITY, INNATE; MACROPHAGES; MICE; MICROBIAL VIABILITY; MONOCYTES; PHAGOCYTOSIS; REACTIVE OXYGEN SPECIES; SEQUENCE HOMOLOGY, AMINO ACID; VIRULENCE FACTORS;

EID: 84959176762     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2016.02.001     Document Type: Article

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