Increased Autoreactivity of the Complement-Activating Molecule Mannan-Binding Lectin in a Type 1 Diabetes Model

Journal of Diabetes Research

Volumn 2016, Issue , 2016, Pages

  Østergaard, Jakob Appel ^a,b   Ruseva, Marieta Milkova ^c   Malik, Talat Habib ^c   Hoffmann Petersen, Ingeborg Torp ^a   Pickering, Matthew Caleb ^c   Thiel, Steffen ^d   Hansen, Troels Krarup ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b Danish Diabetes Academy   (Denmark)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d AARHUS UNIVERSITY   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; COMPLEMENT COMPONENT C3; COMPLEMENT COMPONENT C3A; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C9; GLUCOSE; MANNAN BINDING LECTIN; GLUCOSE BLOOD LEVEL; MANNOSE BINDING LECTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD GLUCOSE MONITORING; BLOOD SAMPLING; BODY WEIGHT; COMPARATIVE STUDY; COMPLEMENT ACTIVATION; COMPLEMENT DEPOSITION; COMPLEMENT SYSTEM; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE DURATION; GLUCOSE BLOOD LEVEL; HOUSEKEEPING GENE; IMMUNOFLUORESCENCE; INSULIN DEPENDENT DIABETES MELLITUS; MALE; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; RISK FACTOR; SIGNAL TRANSDUCTION; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; URINARY EXCRETION; ANIMAL; BLOOD; C57BL MOUSE; COMPLEMENT LECTIN PATHWAY; COMPLICATION; DIABETIC NEPHROPATHIES; EXPERIMENTAL DIABETES MELLITUS; GLOMERULUS; IMMUNOLOGY; METABOLISM;

ANIMALS; BLOOD GLUCOSE; COMPLEMENT ACTIVATION; COMPLEMENT C3A; COMPLEMENT PATHWAY, MANNOSE-BINDING LECTIN; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DIABETIC NEPHROPATHIES; KIDNEY GLOMERULUS; MALE; MANNOSE-BINDING LECTIN; MICE, INBRED C57BL;

EID: 84959141984     PISSN: 23146745     EISSN: 23146753     Source Type: Journal    
DOI: 10.1155/2016/1825738     Document Type: Article

References (37)

1. V. Harjutsalo and P.-H. Groop, "Epidemiology and risk factors for diabetic kidney disease," Advances in Chronic Kidney Disease, vol. 21, no. 3, pp. 260-266, 2014.
2. R. Saran, Y. Li, B. Robinson et al., "US Renal Data System 2014 annual data report: epidemiology of kidney disease in the United States," American Journal of Kidney Diseases, vol. 66, no. 1, supplement 1, p. A7, 2015.
3. EDTA, ERA-EDTA Registry - Annual Report 2013, 2013, http:// www.era-edta-reg.org/files/annualreports/pdf/AnnRep2013.pdf.
4. T. K. Hansen, C. Forsblom, M. Saraheimo et al., "Association between mannose-binding lectin, high-sensitivity C-reactive protein and the progression of diabetic nephropathy in type 1 diabetes," Diabetologia, vol. 53, no. 7, pp. 1517-1524, 2010.
5. T. K. Hansen, L. Tarnow, S. Thiel et al., "Association between mannose-binding lectin and vascular complications in type 1 diabetes," Diabetes, vol. 53, no. 6, pp. 1570-1576, 2004.
6. T. K. Hansen, S. Thiel, S. T. Knudsen et al., "Elevated levels of mannan-binding lectin in patients with type 1 diabetes," Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 10, pp. 4857-4861, 2003.
7. P. Hovind, T. K. Hansen, L. Tarnow et al., "Mannose-binding lectin as a predictor of microalbuminuria in type 1 diabetes: an inception cohort study," Diabetes, vol. 54, no. 5, pp. 1523-1527, 2005.
8. M. A. Kaunisto, L. Sjölind, R. Sallinen et al., "Elevated MBL concentrations are not an indication of association between the MBL2 gene and type 1 diabetes or diabetic nephropathy," Diabetes, vol. 58, no. 7, pp. 1710-1714, 2009.
9. M. Saraheimo, C. Forsblom, T. K. Hansen et al., "Increased levels of mannan-binding lectin in type 1 diabetic patients with incipient and overt nephropathy," Diabetologia, vol. 48, no. 1, pp. 198-202, 2005.
10. J. A. Østergaard, S. Thiel, M. Lajer et al., "Increased all-cause mortality in patients with type 1 diabetes and high-expression mannan-binding lectin genotypes: a 12-year follow-up study," Diabetes Care, vol. 38, no. 10, pp. 1898-1903, 2015.
11. J. Østergaard, S. Thiel, M. Gadjeva, T. K. Hansen, R. Rasch, and A. Flyvbjerg, "Mannose-binding lectin deficiency attenuates renal changes in a streptozotocin-induced model of type 1 diabetes in mice," Diabetologia, vol. 50, no. 7, pp. 1541-1549, 2007.
12. J. A. Østergaard, M. Bjerre, S. P. Ramachandrarao et al., "Mannan-binding lectin in diabetic kidney disease: the impact of mouse genetics in a type 1 diabetes model," Experimental Diabetes Research, vol. 2012, Article ID 678381, 9 pages, 2012.
13. J. Fortpied, D. Vertommen, and E. Van Schaftingen, "Binding of mannose-binding lectin to fructosamines: a potential link between hyperglycaemia and complement activation in diabetes," Diabetes/Metabolism Research and Reviews, vol. 26, no. 4, pp. 254-260, 2010.
14. W.-X. Fan, S.-M. Huang, F. Liu et al., "Activation of the lectin complement pathway on human renal glomerular endothelial cells triggered by high glucose and mannose-binding lectin," African Journal of Biotechnology, vol. 10, no. 80, pp. 18539-18549, 2011.
15. M. P. Cohen, E. Urdanivia, M. Surma, and V. Y. Wu, "Increased glycosylation of glomerular basement membrane collagen in diabetes," Biochemical and Biophysical Research Communications, vol. 95, no. 2, pp. 765-769, 1980.
16. Y. Nishio, C. E. Warren, J. A. Buczek-Thomas et al., "Identification and characterization of a gene regulating enzymatic glycosylation which is induced by diabetes and hyperglycemia specifically in rat cardiac tissue," The Journal of Clinical Investigation, vol. 96, no. 4, pp. 1759-1767, 1995.
17. M. Brownlee, H. Vlassara, and A. Cerami, "Nonenzymatic glycosylation and the pathogenesis of diabetic complications," Annals of Internal Medicine, vol. 101, no. 4, pp. 527-537, 1984.
18. A. Ravidà, L. Musante, M. Kreivi et al., "Glycosylation patterns of kidney proteins differ in rat diabetic nephropathy," Kidney International, vol. 87, no. 5, pp. 963-974, 2015.
19. H. Holthofer, E. Pettersson, and T. Tornroth, "Diabetes mellitus associated changes in glomerular glycocompounds: a fluorescence microscopical study," Histochemical Journal, vol. 19, no. 6-7, pp. 351-356, 1987.
20. T. H. Rosenquist and T. Huff, "Lectin binding in the diabetic rat kidney," Histochemistry, vol. 83, no. 4, pp. 279-284, 1985.
21. C. S. Lee, S. M. Mauer, D. M. Brown, D. E. Sutherland, A. F. Michael, and J. S. Najarian, "Renal transplantation in diabetes mellitus in rats," The Journal of Experimental Medicine, vol. 139, no. 4, pp. 793-800, 1974.
22. S. M. Mauer, M. W. Steffes, D. E. R. Sutherland, Najarian-S, A. F. Michael, and D. M. Brown, "Studies of the rate of regression of the glomerular lesions in diabetic rats treated with pancreatic islet transplantation," Diabetes, vol. 24, no. 3, pp. 280-285, 1975.
23. S. M. Mauer, D. E. R. Sutherland, M. W. Steffes et al., "Pancreatic islet transplantation. Effects on the glomerular lesions of experimental diabetes in the rat," Diabetes, vol. 23, no. 9, pp. 748-753, 1974.
24. J. Acosta, J. Hettinga, R. Flückiger et al., "Molecular basis for a link between complement and the vascular complications of diabetes," Proceedings of the National Academy of Sciences of the United States of America, vol. 97, no. 10, pp. 5450-5455, 2000.
25. X. Qin, A. Goldfine, N. Krumrei et al., "Glycation inactivation of the complement regulatory protein CD59: a possible role in the pathogenesis of the vascular complications of human diabetes," Diabetes, vol. 53, no. 10, pp. 2653-2661, 2004.
26. J. A. Halperin, A. Taratuska, and A. Nicholson-Weller, "Terminal complement complex C5b-9 stimulates mitogenesis in 3T3 cells," The Journal of Clinical Investigation, vol. 91, no. 5, pp. 1974-1978, 1993.
27. L. R. Benzaquen, A. Nicholson-Weller, and J. A. Halperin, "Terminal complement proteins C5b-9 release basic fibroblast growth factor and platelet-derived growth factor from endothelial cells," The Journal of Experimental Medicine, vol. 179, no. 3, pp. 985-992, 1994.
28. G. H. Tesch and T. J. Allen, "Rodent models of streptozotocin-induced diabetic nephropathy (Methods in Renal Research)," Nephrology, vol. 12, no. 3, pp. 261-266, 2007.
29. T. H. Malik, A. Cortini, D. Carassiti, J. J. Boyle, D. O. Haskard, and M. Botto, "The alternative pathway is critical for pathogenic complement activation in endotoxin- and diet-induced atherosclerosis in low-density lipoprotein receptor-deficient mice," Circulation,vol. 122, no. 19, pp. 1948-1956, 2010.
30. H. Liu, L. Jensen, S. Hansen et al., "Characterization and quantification of mouse mannan-binding lectins (MBL-A and MBL-C) and study of acute phase responses," Scandinavian Journal of Immunology, vol. 53, no. 5, pp. 489-497, 2001.
31. M. G. Robson, H. T. Cook, M. Botto et al., "Accelerated nephrotoxic nephritis is exacerbated in C1q-deficient mice," Journal of Immunology, vol. 166, no. 11, pp. 6820-6828, 2001.
32. T. Yamamoto, "Isolation and enrichment of glomeruli using sieving techniques," in Renal and Urinary Proteomics, pp. 1-7, Wiley-VCH, 2009.
33. S. Thiel, "Complement activating soluble pattern recognition molecules with collagen-like regions, mannan-binding lectin, ficolins and associated proteins," Molecular Immunology, vol. 44, no. 16, pp. 3875-3888, 2007.
34. A. J. Nauta, G. Castellano, W. Xu et al., "Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells," The Journal of Immunology, vol. 173, no. 5, pp. 3044-3050, 2004.
35. D. Ricklin, G. Hajishengallis, K. Yang, and J. D. Lambris, "Complement: a key system for immune surveillance and homeostasis," Nature Immunology, vol. 11, no. 9, pp. 785-797, 2010.
36. T. E. Mollnes, P. Garred, and G. Bergseth, "Effect of time, temperature and anticoagulants on in vitro complement activation: consequences for collection and preservation of samples to be examined for complement activation," Clinical & Experimental Immunology, vol. 73, no. 3, pp. 484-488, 1988.
37. K. I. Woroniecka, A. S. D. Park, D. Mohtat, D. B. Thomas, J. M. Pullman, and K. Susztak, "Transcriptome analysis of human diabetic kidney disease," Diabetes, vol. 60, no. 9, pp. 2354-2369, 2011.