Oriented growth and transdifferentiation of mesenchymal stem cells towards a Schwann cell fate on micropatterned substrates

Journal of Bioscience and Bioengineering

Volumn 121, Issue 3, 2016, Pages 325-335

  Sharma, Anup D ^a,b   Zbarska, Svitlana ^b   Petersen, Emma M ^b   Marti, Mustafa E ^a   Mallapragada, Surya K ^a,b   Sakaguchi, Donald S ^b  

^a Iowa State University   (United States)

^b IOWA STATE UNIVERSITY   (United States)

Author keywords

Mesenchymal stem cells; Micropatterning; Polymeric films; Schwann cells; Transdifferentiation

Indexed keywords

ASPECT RATIO; BIOCOMPATIBILITY; BIODEGRADABLE POLYMERS; CELLS; CYTOLOGY; FLOWCHARTING; NEURONS; SCAFFOLDS (BIOLOGY); STEM CELLS; SUBSTRATES;

MESENCHYMAL STEM CELL; MICRO PATTERNING; MICROPATTERNED SUBSTRATES; PATTERNED SUBSTRATES; PERIPHERAL NERVE REGENERATION; SCHWANN CELLS; SMOOTH SUBSTRATES; TRANS DIFFERENTIATIONS;

CELL CULTURE;

ALPHA P75 NTR PROTEIN; ALPHA S100 BETA PROTEIN; NEUROTROPHIN RECEPTOR P75; POLYLACTIC ACID; POLYSTYRENE; PROTEIN S100B; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; LACTIC ACID; POLYESTER; POLYLACTIDE; POLYMER; POLYSTYRENE DERIVATIVE;

ANIMAL CELL; ANTIBODY LABELING; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL ELONGATION; CELL FATE; CELL GROWTH; CELL PROLIFERATION; CELL STRUCTURE; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; IN VITRO STUDY; NONHUMAN; PHENOTYPE; QUANTITATIVE ANALYSIS; RAT; SCHWANN CELL; ANIMAL; CELL CULTURE TECHNIQUE; CELL DIVISION; CELL LINEAGE; CELL SHAPE; CYTOLOGY; DRUG EFFECTS; MESENCHYMAL STROMA CELL; METABOLISM; NERVE REGENERATION; PROCEDURES;

ANIMALS; BIOMARKERS; CELL CULTURE TECHNIQUES; CELL DIVISION; CELL LINEAGE; CELL SHAPE; CELL TRANSDIFFERENTIATION; LACTIC ACID; MESENCHYMAL STROMAL CELLS; NERVE REGENERATION; POLYESTERS; POLYMERS; POLYSTYRENES; RATS; SCHWANN CELLS;

EID: 84959124842     PISSN: 13891723     EISSN: 13474421     Source Type: Journal    
DOI: 10.1016/j.jbiosc.2015.07.006     Document Type: Article

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