Evaluation of KIF23 variant 1 expression and relevance as a novel prognostic factor in patients with hepatocellular carcinoma

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Sun, Xiaotong ^a   Jin, Zhongtian ^a   Song, Xiao ^a   Wang, Jingjing ^a   Li, Yan ^a   Qian, Xiaoping ^a   zhang, Yu ^a   Yin, Yanhui ^a  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Hepatocellular carcinoma; Immunohistochemisty; KIF23; Overall survival; Prognostic factor

Indexed keywords

KIF23 PROTEIN; KINESIN; POLYCLONAL ANTIBODY; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; ISOPROTEIN; KIF23 PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; TUMOR MARKER;

ADULT; AGED; ALTERNATIVE RNA SPLICING; ANTIBODY SPECIFICITY; ARTICLE; CANCER PROGNOSIS; CELL NUCLEUS; CLINICAL FEATURE; CONTROLLED STUDY; CYTOPLASM; DISEASE ASSOCIATION; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; OVERALL SURVIVAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; VERY ELDERLY; WESTERN BLOTTING; BIOSYNTHESIS; DNA MICROARRAY; GENETICS; LIVER TUMOR; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL;

ADULT; AGED; AGED, 80 AND OVER; BIOMARKERS, TUMOR; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROTEIN ISOFORMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84959112958     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1987-1     Document Type: Article

References (22)

1. Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005;55(2):74-108.
2. Xu L, Qian G, Tang L, Su J, Wang JS. Genetic variations of hepatitis B virus and serum aflatoxin-lysine adduct on high risk of hepatocellular carcinoma in Southern Guangxi, China. J Hepatol. 2010;53(4):671-6.
3. Kew MC, Yu MC, Kedda MA, Coppin A, Sarkin A, Hodkinson J. The relative roles of hepatitis B and C viruses in the etiology of hepatocellular carcinoma in southern African blacks. Gastroenterology. 1997;112(1):184-7.
4. Parkin DM. The global health burden of infection-associated cancers in the year 2002. Int J Cancer. 2006;118(12):3030-44.
5. Shi YY, Wang HC, Yin YH, Sun WS, Li Y, Zhang CQ, et al. Identification and analysis of tumour-associated antigens in hepatocellular carcinoma. Br J Cancer. 2005;92(5):929-34.
6. Yi Y, Wu H, Gao Q, He HW, Li YW, Cai XY, et al. Interferon regulatory factor (IRF)-1 and IRF-2 are associated with prognosis and tumor invasion in HCC. Ann Surg Oncol. 2013;20(1):267-76.
7. Chen D, Xing W, Hong J, Wang M, Huang Y, Zhu C, et al. The beta2-adrenergic receptor is a potential prognostic biomarker for human hepatocellular carcinoma after curative resection. Ann Surg Oncol. 2012;19(11):3556-65.
8. Nislow C, Lombillo VA, Kuriyama R, McIntosh JR. A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles. Nature. 1992;359(6395):543-7.
9. Zhu C, Bossy-Wetzel E, Jiang W. Recruitment of MKLP1 to the spindle midzone/midbody by INCENP is essential for midbody formation and completion of cytokinesis in human cells. Biochem J. 2005;389(Pt 2):373-81.
10. Chen MC, Zhou Y, Detrich 3rd HW. Zebrafish mitotic kinesin-like protein 1 (Mklp1) functions in embryonic cytokinesis. Physiol Genomics. 2002;8(1):51-66.
11. Zhu C, Zhao J, Bibikova M, Leverson JD, Bossy-Wetzel E, Fan JB, et al. Functional analysis of human microtubule-based motor proteins, the kinesins and dyneins, in mitosis/cytokinesis using RNA interference. Mol Biol Cell. 2005;16(7):3187-99.
12. Liu X, Zhou T, Kuriyama R, Erikson RL. Molecular interactions of Polo-like-kinase 1 with the mitotic kinesin-like protein CHO1/MKLP-1. J Cell Sci. 2004;117(Pt 15):3233-46.
13. Weinberg RA. Cancer Biology and Therapy: the road ahead. Cancer Biol Ther. 2002;1(1):3.
14. Valk K, Vooder T, Kolde R, Reintam MA, Petzold C, Vilo J, et al. Gene expression profiles of non-small cell lung cancer: survival prediction and new biomarkers. Oncology. 2010;79(3-4):283-92.
15. Takahashi S, Fusaki N, Ohta S, Iwahori Y, Iizuka Y, Inagawa K, et al. Downregulation of KIF23 suppresses glioma proliferation. J Neurooncol. 2012;106(3):519-29.
16. Kuriyama R, Gustus C, Terada Y, Uetake Y, Matuliene J. CHO1, a mammalian kinesin-like protein, interacts with F-actin and is involved in the terminal phase of cytokinesis. J Cell Biol. 2002;156(5):783-90.
17. Hao J, Shen R, Li Y, Zhang Y, Yin Y. Cancer-testis antigen HCA587/MAGE-C2 interacts with BS69 and promotes its degradation in the ubiquitin-proteasome pathway. Biochem Biophys Res Commun. 2014;449(4):386-91.
18. Dong XY, Peng JR, Ye YJ, Chen HS, Zhang LJ, Pang XW, et al. Plac1 is a tumor-specific antigen capable of eliciting spontaneous antibody responses in human cancer patients. Int J Cancer. 2008;122(9):2038-43.
19. Christoph DC, Kasper S, Gauler TC, Loesch C, Engelhard M, Theegarten D, et al. betaV-tubulin expression is associated with outcome following taxane-based chemotherapy in non-small cell lung cancer. Br J Cancer. 2012;107(5):823-30.
20. Miki H, Setou M, Kaneshiro K, Hirokawa N. All kinesin superfamily protein, KIF, genes in mouse and human. Proc Natl Acad Sci U S A. 2001;98(13):7004-11.
21. Glotzer M. The molecular requirements for cytokinesis. Science. 2005;307(5716):1735-9.
22. Fischer M, Grundke I, Sohr S, Quaas M, Hoffmann S, Knorck A, et al. p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes. PLoS One. 2013;8(5):e63187.