Death following ingestion of methylone

International Journal of Legal Medicine

Volumn 130, Issue 2, 2016, Pages 381-385

  Barrios, L ^a   Grison Hernando, H ^a   Boels, D ^b   Bouquie, R ^a   Monteil Ganiere, C ^a   Clement, R ^a  

^a NANTES UNIVERSITY HOSPITAL   (France)

^b ANGERS UNIVERSITY HOSPITAL   (France)

Author keywords

Anoxia; Cathinones; Death; Methylone; Respiratory inhibition

Indexed keywords

CENTRAL STIMULANT AGENT; DRONABINOL; METHAMPHETAMINE; METHYLONE; PSYCHOTROPIC AGENT;

ANALOGS AND DERIVATIVES; BILE; CASE REPORT; CHEMISTRY; COMPLICATION; DRUG DEPENDENCE; FORENSIC TOXICOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MALE; MASS FRAGMENTOGRAPHY; ORAL DRUG ADMINISTRATION; STOMACH JUICE; VITREOUS BODY; YOUNG ADULT;

ADMINISTRATION, ORAL; BILE; CENTRAL NERVOUS SYSTEM STIMULANTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRONABINOL; FORENSIC TOXICOLOGY; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GASTROINTESTINAL CONTENTS; HUMANS; MALE; METHAMPHETAMINE; PSYCHOTROPIC DRUGS; SUBSTANCE-RELATED DISORDERS; VITREOUS BODY; YOUNG ADULT;

EID: 84959077665     PISSN: 09379827     EISSN: 14371596     Source Type: Journal    
DOI: 10.1007/s00414-015-1212-4     Document Type: Article

References (17)

1. Tekulve K, Alexander A, Tormoehlen L (2014) Seizures associated with synthetic cathinone exposures in the pediatric population. Pediatr Neurol 51(1):67–70
2. Prosser JM, Nelson LS (2012) The toxicology of bath salts: a review of synthetic cathinones. J Med Toxicol Off J Am Coll Med Toxicol 8(1):33–42
3. López-Arnau R, Martínez-Clemente J, Abad S, Pubill D, Camarasa J, Escubedo E (2014) Repeated doses of methylone, a new drug of abuse, induce changes in serotonin and dopamine systems in the mouse. Psychopharmacology (Berl) 231(16):3119–29
4. Uralets V, Rana S, Morgan S, Ross W (2014) Testing for designer stimulants: metabolic profiles of 16 synthetic cathinones excreted free in human urine. J Anal Toxicol 38(5):233–41
5. Baumann MH, Partilla JS, Lehner KR (2013) Psychoactive “bath salts”: not so soothing. Eur J Pharmacol 698(1–3):1–5
6. Warrick BJ, Wilson J, Hedge M, Freeman S, Leonard K, Aaron C (2012) Lethal serotonin syndrome after methylone and butylone ingestion. J Med Toxicol Off J Am Coll Med Toxicol 8(1):65–8
7. Jacob P, Shulgin A (1996) Novel n-substituted-2-amino-3’,4’-methylene-dioxypropiophenones - WO1996039133A1
8. Bossong MG, Van Dijk JP, Niesink RJM (2005) Methylone and mCPP, two new drugs of abuse? Addict Biol 10(4):321–3
9. Sogawa C, Sogawa N, Ohyama K, Kikura-Hanajiri R, Goda Y, Sora I et al (2011) Methylone and monoamine transporters: correlation with toxicity. Curr Neuropharmacol 9(1):58–62
10. Nagai F, Nonaka R, Satoh Hisashi Kamimura K (2007) The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. Eur J Pharmacol 559(2-3):132–7
11. Pearson JM, Hargraves TL, Hair LS, Massucci CJ, Frazee CC, Garg U et al (2012) Three fatal intoxications due to methylone. J Anal Toxicol 36(6):444–51
12. Carbone PN, Carbone DL, Carstairs SD, Luzi SA (2013) Sudden cardiac death associated with methylone use. Am J Forensic Med Pathol 34(1):26–8
13. Cawrse BM, Levine B, Jufer RA, Fowler DR, Vorce SP, Dickson AJ et al (2012) Distribution of methylone in four postmortem cases. J Anal Toxicol 36(6):434–9
14. McIntyre IM, Hamm CE, Aldridge L, Nelson CL (2013) Acute methylone intoxication in an accidental drowning – a case report. Forensic Sci Int 231(1-3):e1–3
15. Marinetti LJ, Antonides HM (2013) Analysis of synthetic cathinones commonly found in bath salts in human performance and postmortem toxicology: method development, drug distribution and interpretation of results. J Anal Toxicol 37(3):135–46
16. Kovács K, Tóth AR, Kereszty EM (2012) A new designer drug: methylone related death. Orv Hetil 153(7):271–6
17. Baselt RC (2008) Disposition of toxic drugs and chemicals in man. Édition: 8. Foster City, Ca: Biomedical Publications