Febuxostat-induced acute liver injury

Hepatology

Volumn 63, Issue 3, 2016, Pages 1047-1049

  Bohm, Matt ^a   Vuppalanchi, Raj ^a   Chalasani, N ^b   Fontana, R J ^b   Watkins, P B ^b   Bonkovsky, H L ^b   Davern, T ^b   Serrano, J ^b   Rochon, J ^b  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALLOPURINOL; BILIRUBIN; COLCHICINE; FEBUXOSTAT; ANTIGOUT AGENT;

ABDOMINAL PAIN; ACUTE PANCREATITIS; ADD ON THERAPY; ADULT; ARTICLE; BILIRUBIN BLOOD LEVEL; CASE REPORT; CHOLESTASIS; DRUG WITHDRAWAL; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FATIGUE; GOUT; HUMAN; HUMAN TISSUE; INTRAHEPATIC CHOLESTASIS; JAUNDICE; LIVER BIOPSY; LIVER INJURY; MALE; OBESITY; PRIORITY JOURNAL; CHEMICAL AND DRUG INDUCED LIVER INJURY; LIVER; PATHOLOGY;

ADULT; CHEMICAL AND DRUG INDUCED LIVER INJURY; FEBUXOSTAT; GOUT SUPPRESSANTS; HUMANS; LIVER; MALE;

EID: 84959054418     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.28403     Document Type: Article

References (5)

1. Bruce SP. Febuxostat: a selective xanthine oxidase inhibitor for the treatment of hyperuricemia and gout. Ann Pharmacother 2006;40:2187-2194.
2. Becker MA, Schumacher HR, MacDonald PA, Lloyd E, Lademacher C. Clinical efficacy and safety of successful longterm urate lowering with febuxostat or allopurinol in patients with gout. J Rheumatol 2009;36:1273-1282.
3. Becker MA, Schumacher HR, Jr., Wortmann RL, MacDonald PA, Palo WA, Eustace D, et al. Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med 2005;353:2450-2461.
4. LiverTox Database. Febuxostat. Available at: http://livertox.nlm.nih.gov. Accessed August 10, 2014.
5. Fontana RJ, Watkins PB, Bonkovsky HL, Chalasani N, Davern T, Serrano J, Rochon J; DILIN Study Group. Drug-Induced Liver Injury Network (DILIN) prospective study: rationale, design and conduct. Drug Saf 2009;32:55-68.