메뉴 건너뛰기




Volumn 7, Issue , 2016, Pages

Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS AND CELL COMPONENTS; DATA SET; GENE EXPRESSION; GENETIC MARKER; NERVOUS SYSTEM DISORDER; RISK FACTOR; SEXUAL DIMORPHISM;

EID: 84959017595     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10717     Document Type: Article
Times cited : (204)

References (70)
  • 2
    • 84900527418 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorder among children aged 8 years-Autism and Developmental Disabilities Monitoring Network, 11 sites, United States 2010
    • Wingate, M. et al. Prevalence of autism spectrum disorder among children aged 8 years-Autism and Developmental Disabilities Monitoring Network, 11 sites, United States, 2010. MMWR Surveill. Summ. 63, 1-21 (2014).
    • (2014) MMWR Surveill. Summ. , vol.63 , pp. 1-21
    • Wingate, M.1
  • 3
    • 80051944739 scopus 로고    scopus 로고
    • Genetic heritability and shared environmental factors among twin pairs with autism
    • Hallmayer, J. et al. Genetic heritability and shared environmental factors among twin pairs with autism. Arch. Gen. Psychiatry 68, 1095-1102 (2011).
    • (2011) Arch. Gen. Psychiatry , vol.68 , pp. 1095-1102
    • Hallmayer, J.1
  • 5
    • 80052366179 scopus 로고    scopus 로고
    • Recurrence risk for autism spectrum disorders: A Baby Siblings Research Consortium study
    • Ozonoff, S. et al. Recurrence risk for autism spectrum disorders: a Baby Siblings Research Consortium study. Pediatrics 128, e488-e495 (2011).
    • (2011) Pediatrics , vol.128 , pp. e488-e495
    • Ozonoff, S.1
  • 6
    • 42349095075 scopus 로고    scopus 로고
    • Advances in autism genetics: On the threshold of a new neurobiology
    • Abrahams, B. S., Geschwind, D. H. Advances in autism genetics: on the threshold of a new neurobiology. Nat. Rev. Genet. 9, 341-355 (2008).
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 341-355
    • Abrahams, B.S.1    Geschwind, D.H.2
  • 7
    • 84912144889 scopus 로고    scopus 로고
    • Synaptic, transcriptional and chromatin genes disrupted in autism
    • De Rubeis, S. et al. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature 515, 209-215 (2014).
    • (2014) Nature , vol.515 , pp. 209-215
    • De Rubeis, S.1
  • 8
    • 84912101541 scopus 로고    scopus 로고
    • The contribution of de novo coding mutations to autism spectrum disorder
    • Iossifov, I. et al. The contribution of de novo coding mutations to autism spectrum disorder. Nature 515, 216-221 (2014).
    • (2014) Nature , vol.515 , pp. 216-221
    • Iossifov, I.1
  • 9
    • 84942113437 scopus 로고    scopus 로고
    • Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci
    • Sanders, S. J. et al. Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci. Neuron 87, 1215-1233 (2015).
    • (2015) Neuron , vol.87 , pp. 1215-1233
    • Sanders, S.J.1
  • 10
    • 84860780495 scopus 로고    scopus 로고
    • De novo mutations revealed by whole-exome sequencing are strongly associated with autism
    • Sanders, S. J. et al. De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature 485, 237-241 (2012).
    • (2012) Nature , vol.485 , pp. 237-241
    • Sanders, S.J.1
  • 11
    • 67049118065 scopus 로고    scopus 로고
    • Epidemiology of pervasive developmental disorders
    • Fombonne, E. Epidemiology of pervasive developmental disorders. Pediatr. Res. 65, 591-598 (2009).
    • (2009) Pediatr. Res. , vol.65 , pp. 591-598
    • Fombonne, E.1
  • 12
    • 84874939983 scopus 로고    scopus 로고
    • Sex differences in autism spectrum disorders
    • Werling, D. M., Geschwind, D. H. Sex differences in autism spectrum disorders. Curr. Opin. Neurol. 26, 146-153 (2013).
    • (2013) Curr. Opin. Neurol. , vol.26 , pp. 146-153
    • Werling, D.M.1    Geschwind, D.H.2
  • 13
    • 34547886497 scopus 로고    scopus 로고
    • A unified genetic theory for sporadic and inherited autism
    • Zhao, X. et al. A unified genetic theory for sporadic and inherited autism. Proc. Natl Acad. Sci. USA 104, 12831-12836 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 12831-12836
    • Zhao, X.1
  • 15
    • 84895920717 scopus 로고    scopus 로고
    • A higher mutational burden in females supports a 'female protective model' in neurodevelopmental disorders
    • Jacquemont, S. et al. A higher mutational burden in females supports a 'female protective model' in neurodevelopmental disorders. Am. J. Hum. Genet. 94, 415-425 (2014).
    • (2014) Am. J. Hum. Genet. , vol.94 , pp. 415-425
    • Jacquemont, S.1
  • 16
    • 6544270937 scopus 로고    scopus 로고
    • Autistic behavior in young boys with fragile X syndrome
    • Bailey, Jr D. B. et al. Autistic behavior in young boys with fragile X syndrome. J. Autism Dev. Disord. 28, 499-508 (1998).
    • (1998) J. Autism Dev. Disord. , vol.28 , pp. 499-508
    • Bailey, D.B.1
  • 17
    • 0037656313 scopus 로고    scopus 로고
    • Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism
    • Jamain, S. et al. Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism. Nat. Genet. 34, 27-29 (2003).
    • (2003) Nat. Genet. , vol.34 , pp. 27-29
    • Jamain, S.1
  • 18
    • 8844244724 scopus 로고    scopus 로고
    • Evidence for sex-specific risk alleles in autism spectrum disorder
    • Stone, J. L. et al. Evidence for sex-specific risk alleles in autism spectrum disorder. Am. J. Hum. Genet. 75, 1117-1123 (2004).
    • (2004) Am. J. Hum. Genet. , vol.75 , pp. 1117-1123
    • Stone, J.L.1
  • 19
    • 84895925000 scopus 로고    scopus 로고
    • Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder
    • Werling, D. M., Lowe, J. K., Luo, R., Cantor, R. M., Geschwind, D. H. Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder. Mol. Autism 5, 13 (2014).
    • (2014) Mol. Autism , vol.5 , pp. 13
    • Werling, D.M.1    Lowe, J.K.2    Luo, R.3    Cantor, R.M.4    Geschwind, D.H.5
  • 20
    • 0033963470 scopus 로고    scopus 로고
    • Imprinting the X-chromosome, and the male brain: Explaining sex differences in the liability to autism
    • Skuse, D. H. Imprinting, the X-chromosome, and the male brain: explaining sex differences in the liability to autism. Pediatr. Res. 47, 9-16 (2000).
    • (2000) Pediatr. Res. , vol.47 , pp. 9-16
    • Skuse, D.H.1
  • 21
    • 0036606475 scopus 로고    scopus 로고
    • The extreme male brain theory of autism
    • Baron-Cohen, S. The extreme male brain theory of autism. Trends Cogn. Sci. 6, 248-254 (2002).
    • (2002) Trends Cogn. Sci. , vol.6 , pp. 248-254
    • Baron-Cohen, S.1
  • 22
    • 84924743530 scopus 로고    scopus 로고
    • Elevated fetal steroidogenic activity in autism
    • Baron-Cohen, S. et al. Elevated fetal steroidogenic activity in autism. Mol. Psychiatry 20, 369-376 (2014).
    • (2014) Mol. Psychiatry , vol.20 , pp. 369-376
    • Baron-Cohen, S.1
  • 23
    • 84923384915 scopus 로고    scopus 로고
    • Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism
    • Gupta, S. et al. Transcriptome analysis reveals dysregulation of innate immune response genes and neuronal activity-dependent genes in autism. Nat. Commun. 5, 5748 (2014).
    • (2014) Nat. Commun. , vol.5 , pp. 5748
    • Gupta, S.1
  • 24
    • 79959262465 scopus 로고    scopus 로고
    • Transcriptomic analysis of autistic brain reveals convergent molecular pathology
    • Voineagu, I. et al. Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature 474, 380-384 (2011).
    • (2011) Nature , vol.474 , pp. 380-384
    • Voineagu, I.1
  • 25
    • 9744255446 scopus 로고    scopus 로고
    • Microarray analysis of activated mixed glial (microglia) and monocyte-derived macrophage gene expression
    • Albright, A. V., Gonzalez-Scarano, F. Microarray analysis of activated mixed glial (microglia) and monocyte-derived macrophage gene expression. J. Neuroimmunol. 157, 27-38 (2004).
    • (2004) J. Neuroimmunol. , vol.157 , pp. 27-38
    • Albright, A.V.1    Gonzalez-Scarano, F.2
  • 26
    • 38149129457 scopus 로고    scopus 로고
    • A transcriptome database for astrocytes, neurons, and oligodendrocytes: A new resource for understanding brain development and function
    • Cahoy, J. D. et al. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J. Neurosci. 28, 264-278 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 264-278
    • Cahoy, J.D.1
  • 27
    • 84924565530 scopus 로고    scopus 로고
    • Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
    • Zeisel, A. et al. Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq. Science 347, 1138-1142 (2015).
    • (2015) Science , vol.347 , pp. 1138-1142
    • Zeisel, A.1
  • 28
    • 84903612456 scopus 로고    scopus 로고
    • BrainSpan Consortium Available [Accessed 31 October 2013]
    • BrainSpan Consortium. BrainSpan: Atlas of the Developing Human Brain. Available: http://www.brainspan.org (2013) [Accessed 31 October 2013].
    • (2013) BrainSpan: Atlas of the Developing Human Brain
  • 29
    • 80054993342 scopus 로고    scopus 로고
    • Spatio-temporal transcriptome of the human brain
    • Kang, H. J. et al. Spatio-temporal transcriptome of the human brain. Nature 478, 483-489 (2011).
    • (2011) Nature , vol.478 , pp. 483-489
    • Kang, H.J.1
  • 30
    • 84889561601 scopus 로고    scopus 로고
    • Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism
    • Parikshak, N. N. et al. Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell 155, 1008-1021 (2013).
    • (2013) Cell , vol.155 , pp. 1008-1021
    • Parikshak, N.N.1
  • 31
    • 84889583293 scopus 로고    scopus 로고
    • Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism
    • Willsey, A. J. et al. Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism. Cell 155, 997-1007 (2013).
    • (2013) Cell , vol.155 , pp. 997-1007
    • Willsey, A.J.1
  • 32
    • 58149178561 scopus 로고    scopus 로고
    • AutDB: A gene reference resource for autism research
    • Basu, S. N., Kollu, R., Banerjee-Basu, S. AutDB: a gene reference resource for autism research. Nucleic Acids Res. 37, D832-D836 (2009).
    • (2009) Nucleic Acids Res. , vol.37 , pp. D832-D836
    • Basu, S.N.1    Kollu, R.2    Banerjee-Basu, S.3
  • 33
    • 79960779323 scopus 로고    scopus 로고
    • FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism
    • Darnell, J. C. et al. FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism. Cell 146, 247-261 (2011).
    • (2011) Cell , vol.146 , pp. 247-261
    • Darnell, J.C.1
  • 34
    • 84878242024 scopus 로고    scopus 로고
    • Identification of transcriptional regulators in the mouse immune system
    • Jojic, V. et al. Identification of transcriptional regulators in the mouse immune system. Nat. Immunol. 14, 633-643 (2013).
    • (2013) Nat. Immunol. , vol.14 , pp. 633-643
    • Jojic, V.1
  • 35
    • 84888367236 scopus 로고    scopus 로고
    • Widespread sex differences in gene expression and splicing in the adult human brain
    • Trabzuni, D. et al. Widespread sex differences in gene expression and splicing in the adult human brain. Nat. Commun. 4, 2771 (2013).
    • (2013) Nat. Commun. , vol.4 , pp. 2771
    • Trabzuni, D.1
  • 36
    • 10744226630 scopus 로고    scopus 로고
    • Gender-specific gene expression in post-mortem human brain: Localization to sex chromosomes
    • Vawter, M. P. et al. Gender-specific gene expression in post-mortem human brain: localization to sex chromosomes. Neuropsychopharmacology 29, 373-384 (2004).
    • (2004) Neuropsychopharmacology , vol.29 , pp. 373-384
    • Vawter, M.P.1
  • 37
    • 33746681910 scopus 로고    scopus 로고
    • Tissue-specific expression and regulation of sexually dimorphic genes in mice
    • Yang, X. et al. Tissue-specific expression and regulation of sexually dimorphic genes in mice. Genome Res. 16, 995-1004 (2006).
    • (2006) Genome Res. , vol.16 , pp. 995-1004
    • Yang, X.1
  • 38
    • 84938310540 scopus 로고    scopus 로고
    • Different immune cells mediate mechanical pain hypersensitivity in male and female mice
    • Sorge, R. E. et al. Different immune cells mediate mechanical pain hypersensitivity in male and female mice. Nat. Neurosci. 18, 1081-1083 (2015).
    • (2015) Nat. Neurosci. , vol.18 , pp. 1081-1083
    • Sorge, R.E.1
  • 39
    • 54949113578 scopus 로고    scopus 로고
    • Functional organization of the transcriptome in human brain
    • Oldham, M. C. et al. Functional organization of the transcriptome in human brain. Nat. Neurosci. 11, 1271-1282 (2008).
    • (2008) Nat. Neurosci. , vol.11 , pp. 1271-1282
    • Oldham, M.C.1
  • 40
    • 68749092138 scopus 로고    scopus 로고
    • The organization of the transcriptional network in specific neuronal classes
    • Winden, K. D. et al. The organization of the transcriptional network in specific neuronal classes. Mol. Syst. Biol. 5, 291 (2009).
    • (2009) Mol. Syst. Biol. , vol.5 , pp. 291
    • Winden, K.D.1
  • 41
    • 33748645500 scopus 로고    scopus 로고
    • GENCODE: Producing a reference annotation for ENCODE
    • Harrow, J. et al. GENCODE: producing a reference annotation for ENCODE. Genome Biol. 7(Suppl 1): S4 1-S4 9 (2006).
    • (2006) Genome Biol. , vol.7 , pp. S41-S49
    • Harrow, J.1
  • 42
    • 0001864544 scopus 로고
    • The fetal hormonal environment and its effect on the morphogenesis of the genital system
    • (eds Kogan, S. J., Hafez, E. S. E.) (Martinus Nijhoff
    • Smail, P. J., Reyes, F. I., Winter, J. S. D., Faiman, C. The fetal hormonal environment and its effect on the morphogenesis of the genital system. In Pediatric Andrology Vol. 7 (eds Kogan, S. J., Hafez, E. S. E.) 9-19 (Martinus Nijhoff, 1981).
    • (1981) Pediatric Andrology , vol.7 , pp. 9-19
    • Smail, P.J.1    Reyes, F.I.2    Winter, J.S.D.3    Faiman, C.4
  • 44
    • 0033050029 scopus 로고    scopus 로고
    • Gender differences in the human cerebral cortex: More neurons in males; More processes in females
    • Rabinowicz, T., Dean, D. E., Petetot, J. M., de Courten-Myers, G. M. Gender differences in the human cerebral cortex: more neurons in males; more processes in females. J. Child Neurol. 14, 98-107 (1999).
    • (1999) J. Child Neurol. , vol.14 , pp. 98-107
    • Rabinowicz, T.1    Dean, D.E.2    Petetot, J.M.3    De Courten-Myers, G.M.4
  • 46
    • 0033567850 scopus 로고    scopus 로고
    • Steroid-induced developmental plasticity in hypothalamic astrocytes: Implications for synaptic patterning
    • Mong, J. A., McCarthy, M. M. Steroid-induced developmental plasticity in hypothalamic astrocytes: implications for synaptic patterning. J. Neurobiol. 40, 602-619 (1999).
    • (1999) J. Neurobiol. , vol.40 , pp. 602-619
    • Mong, J.A.1    McCarthy, M.M.2
  • 47
    • 0037115045 scopus 로고    scopus 로고
    • Ontogeny of sexually dimorphic astrocytes in the neonatal rat arcuate
    • Mong, J. A., McCarthy, M. M. Ontogeny of sexually dimorphic astrocytes in the neonatal rat arcuate. Dev. Brain Res. 139, 151-158 (2002).
    • (2002) Dev. Brain Res. , vol.139 , pp. 151-158
    • Mong, J.A.1    McCarthy, M.M.2
  • 48
    • 0033135265 scopus 로고    scopus 로고
    • Localization of estrogen receptor beta-immunoreactivity in astrocytes of the adult rat brain
    • Azcoitia, I., Sierra, A., Garcia-Segura, L. M. Localization of estrogen receptor beta-immunoreactivity in astrocytes of the adult rat brain. Glia 26, 260-267 (1999).
    • (1999) Glia , vol.26 , pp. 260-267
    • Azcoitia, I.1    Sierra, A.2    Garcia-Segura, L.M.3
  • 49
    • 58449118703 scopus 로고    scopus 로고
    • Expression of estrogen receptor alpha and beta in reactive astrocytes at the male rat hippocampus after status epilepticus
    • Sakuma, S., Tokuhara, D., Hattori, H., Matsuoka, O., Yamano, T. Expression of estrogen receptor alpha and beta in reactive astrocytes at the male rat hippocampus after status epilepticus. Neuropathology 29, 55-62 (2009).
    • (2009) Neuropathology , vol.29 , pp. 55-62
    • Sakuma, S.1    Tokuhara, D.2    Hattori, H.3    Matsuoka, O.4    Yamano, T.5
  • 50
    • 0032518514 scopus 로고    scopus 로고
    • Prostaglandins stimulate calcium-dependent glutamate release in astrocytes
    • Bezzi, P. et al. Prostaglandins stimulate calcium-dependent glutamate release in astrocytes. Nature 391, 281-285 (1998).
    • (1998) Nature , vol.391 , pp. 281-285
    • Bezzi, P.1
  • 51
    • 68049143450 scopus 로고    scopus 로고
    • Tripartite synapses: Astrocytes process and control synaptic information
    • Perea, G., Navarrete, M., Araque, A. Tripartite synapses: astrocytes process and control synaptic information. Trends Neurosci. 32, 421-431 (2009).
    • (2009) Trends Neurosci. , vol.32 , pp. 421-431
    • Perea, G.1    Navarrete, M.2    Araque, A.3
  • 52
    • 33748281357 scopus 로고    scopus 로고
    • Cooperative astrocyte and dendritic spine dynamics at hippocampal excitatory synapses
    • Haber, M., Zhou, L., Murai, K. K. Cooperative astrocyte and dendritic spine dynamics at hippocampal excitatory synapses. J. Neurosci. 26, 8881-8891 (2006).
    • (2006) J. Neurosci. , vol.26 , pp. 8881-8891
    • Haber, M.1    Zhou, L.2    Murai, K.K.3
  • 53
    • 1242271191 scopus 로고    scopus 로고
    • PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes
    • Hama, H., Hara, C., Yamaguchi, K., Miyawaki, A. PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytes. Neuron 41, 405-415 (2004).
    • (2004) Neuron , vol.41 , pp. 405-415
    • Hama, H.1    Hara, C.2    Yamaguchi, K.3    Miyawaki, A.4
  • 54
    • 0024449952 scopus 로고
    • Ocular dominance plasticity in adult cat visual cortex after transplantation of cultured astrocytes
    • Muller, C. M., Best, J. Ocular dominance plasticity in adult cat visual cortex after transplantation of cultured astrocytes. Nature 342, 427-430 (1989).
    • (1989) Nature , vol.342 , pp. 427-430
    • Muller, C.M.1    Best, J.2
  • 55
    • 84861427387 scopus 로고    scopus 로고
    • Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner
    • Schafer, D. P. et al. Microglia sculpt postnatal neural circuits in an activity and complement-dependent manner. Neuron 74, 691-705 (2012).
    • (2012) Neuron , vol.74 , pp. 691-705
    • Schafer, D.P.1
  • 56
    • 1342266618 scopus 로고    scopus 로고
    • Estradiol modulation of astrocytes and the establishment of sex differences in the brain
    • McCarthy, M. M., Todd, B. J., Amateau, S. K. Estradiol modulation of astrocytes and the establishment of sex differences in the brain. Ann. NY Acad. Sci. 1007, 283-297 (2003).
    • (2003) Ann. NY Acad. Sci. , vol.1007 , pp. 283-297
    • McCarthy, M.M.1    Todd, B.J.2    Amateau, S.K.3
  • 57
    • 82555196668 scopus 로고    scopus 로고
    • Mutations causing syndromic autism define an axis of synaptic pathophysiology
    • Auerbach, B. D., Osterweil, E. K., Bear, M. F. Mutations causing syndromic autism define an axis of synaptic pathophysiology. Nature 480, 63-68 (2011).
    • (2011) Nature , vol.480 , pp. 63-68
    • Auerbach, B.D.1    Osterweil, E.K.2    Bear, M.F.3
  • 58
    • 79958035893 scopus 로고    scopus 로고
    • Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses
    • Gilman, S. R. et al. Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron 70, 898-907 (2011).
    • (2011) Neuron , vol.70 , pp. 898-907
    • Gilman, S.R.1
  • 59
    • 79958204980 scopus 로고    scopus 로고
    • Protein interactome reveals converging molecular pathways among autism disorders
    • Sakai, Y. et al. Protein interactome reveals converging molecular pathways among autism disorders. Sci. Transl. Med. 3, 86ra49 (2011).
    • (2011) Sci. Transl. Med. , vol.3 , pp. 86ra49
    • Sakai, Y.1
  • 60
    • 0024583837 scopus 로고
    • Two sexually dimorphic cell groups in the human brain
    • Allen, L. S., Hines, M., Shryne, J. E., Gorski, R. A. Two sexually dimorphic cell groups in the human brain. J. Neurosci. 9, 497-506 (1989).
    • (1989) J. Neurosci. , vol.9 , pp. 497-506
    • Allen, L.S.1    Hines, M.2    Shryne, J.E.3    Gorski, R.A.4
  • 61
    • 84937520584 scopus 로고    scopus 로고
    • Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders
    • Parikshak, N. N., Gandal, M. J., Geschwind, D. H. Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders. Nat. Rev. Genet. 16, 441-458 (2015).
    • (2015) Nat. Rev. Genet. , vol.16 , pp. 441-458
    • Parikshak, N.N.1    Gandal, M.J.2    Geschwind, D.H.3
  • 62
    • 0032898896 scopus 로고    scopus 로고
    • Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis
    • Kirschbaum, C., Kudielka, B.M., Gaab, J., Schommer, N. C., Hellhammer, D. H. Impact of gender, menstrual cycle phase, and oral contraceptives on the activity of the hypothalamus-pituitary-adrenal axis. Psychosom. Med. 61, 154-162 (1999).
    • (1999) Psychosom. Med. , vol.61 , pp. 154-162
    • Kirschbaum, C.1    Kudielka, B.M.2    Gaab, J.3    Schommer, N.C.4    Hellhammer, D.H.5
  • 63
    • 84858068675 scopus 로고    scopus 로고
    • Removing technical variability in RNA-seq data using conditional quantile normalization
    • Hansen, K. D., Irizarry, R. A., Wu, Z. J. Removing technical variability in RNA-seq data using conditional quantile normalization. Biostatistics 13, 204-216 (2012).
    • (2012) Biostatistics , vol.13 , pp. 204-216
    • Hansen, K.D.1    Irizarry, R.A.2    Wu, Z.J.3
  • 64
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • Johnson, W. E., Li, C., Rabinovic, A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 8, 118-127 (2007).
    • (2007) Biostatistics , vol.8 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 65
    • 33645241407 scopus 로고    scopus 로고
    • The RIN: An RNA integrity number for assigning integrity values to RNA measurements
    • Schroeder, A. et al. The RIN: an RNA integrity number for assigning integrity values to RNA measurements. BMC Mol. Biol. 7, 3 (2006).
    • (2006) BMC Mol. Biol. , vol.7 , pp. 3
    • Schroeder, A.1
  • 66
    • 65449136284 scopus 로고    scopus 로고
    • TopHat: Discovering splice junctions with RNA-Seq
    • Trapnell, C., Pachter, L., Salzberg, S. L. TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25, 1105-1111 (2009).
    • (2009) Bioinformatics , vol.25 , pp. 1105-1111
    • Trapnell, C.1    Pachter, L.2    Salzberg, S.L.3
  • 67
    • 84928987900 scopus 로고    scopus 로고
    • HTSeq-a Python framework to work with high-throughput sequencing data
    • Anders, S., Pyl, P. T., Huber, W. HTSeq-a Python framework to work with high-throughput sequencing data. Bioinformatics 31, 166-169 (2014).
    • (2014) Bioinformatics , vol.31 , pp. 166-169
    • Anders, S.1    Pyl, P.T.2    Huber, W.3
  • 68
    • 84861970118 scopus 로고    scopus 로고
    • Network methods for describing sample relationships in genomic datasets: Application to Huntington's disease
    • Oldham, M. C., Langfelder, P., Horvath, S. Network methods for describing sample relationships in genomic datasets: application to Huntington's disease. BMC Syst. Biol. 6, 63 (2012).
    • (2012) BMC Syst. Biol. , vol.6 , pp. 63
    • Oldham, M.C.1    Langfelder, P.2    Horvath, S.3
  • 70
    • 84860297457 scopus 로고    scopus 로고
    • De novo gene disruptions in children on the autistic spectrum
    • Iossifov, I. et al. De novo gene disruptions in children on the autistic spectrum. Neuron 74, 285-299 (2012).
    • (2012) Neuron , vol.74 , pp. 285-299
    • Iossifov, I.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.