Immunolocalization and Distribution of Rubella Antigen in Fatal Congenital Rubella Syndrome

EBioMedicine

Volumn 3, Issue , 2016, Pages 86-92

  Lazar, Mihaela ^a,c,d   Perelygina, Ludmila ^a   Martines, Roosecelis ^b   Greer, Patricia ^b   Paddock, Christopher D ^b   Peltecu, Gheorghe ^e   Lupulescu, Emilia ^c   Icenogle, Joseph ^a   Zaki, Sherif R ^b  

^a Division of Viral Diseases   (United States)

^b NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^c CANTACUZINO INSTITUTE   (Romania)

^d UNIVERSITY OF BUCHAREST   (Romania)

^e Filantropia Hospital   (Romania)

Author keywords

Autopsy; Congenital rubella syndrome (CRS); CRS pathology; Fatal cases; Immunohistochemistry

Indexed keywords

RUBELLA ANTIBODY; VIRUS ANTIGEN;

ANTIBODY SPECIFICITY; AORTA; APGAR SCORE; ARTICLE; AUTOPSY; CASE REPORT; CENTRAL NERVOUS SYSTEM; CONGENITAL RUBELLA SYNDROME; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HEART; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOLOCALIZATION; IMMUNOPATHOLOGY; LUNG; MALE; PLACENTA; PRIORITY JOURNAL; PULMONARY ARTERY; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UMBILICAL CORD; VIRUS REPLICATION; WESTERN BLOTTING; BIOPSY; CARDIAC MUSCLE; CELL LINE; CLASSIFICATION; FATALITY; GENETICS; IMMUNOLOGY; METABOLISM; NEWBORN; PATHOLOGY; PREGNANCY; RUBELLA SYNDROME, CONGENITAL; RUBELLA VIRUS; TRANSMISSION; VERTICAL TRANSMISSION; VIROLOGY;

ANTIGENS, VIRAL; AUTOPSY; BIOPSY; CELL LINE; CENTRAL NERVOUS SYSTEM; FATAL OUTCOME; FEMALE; HUMANS; INFANT, NEWBORN; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; LUNG; MALE; MYOCARDIUM; PREGNANCY; RUBELLA SYNDROME, CONGENITAL; RUBELLA VIRUS; VIRUS REPLICATION;

EID: 84958871839     PISSN: None     EISSN: 23523964     Source Type: Journal    
DOI: 10.1016/j.ebiom.2015.11.050     Document Type: Article

References (47)

1. Abernathy E., Cabezas C., Sun H., et al. Confirmation of rubella within 4 days of rash onset: comparison of rubella virus RNA detection in oral fluid with immunoglobulin M detection in serum or oral fluid. J. Clin. Microbiol. 2009, 47(1):182-188.
2. Alford C.A., Neva F.A., Weller T.H. Virologic and serologic studies on human products of conception after maternal rubella. N. Engl. J. Med. 1964, 271:1275-1281.
3. Andrus J.K., de Quadros C.A., Solorzano C.C., Periago M.R., Henderson D.A. Measles and rubella eradication in the Americas. Vaccine 2011, 29(Suppl. 4):D91-D96.
4. Boner A., Wilmott R.W., Dinwiddie R., et al. Desquamative interstitial pneumonia and antigen-antibody complexes in two infants with congenital rubella. Pediatrics 1983, 72(6):835-839.
5. Brown A.S., Derkits E.J. Prenatal infection and schizophrenia: a review of epidemiologic and translational studies. Am. J. Psychiatry 2010, 167(3):261-280.
6. Chantler J.K., Smyrnis L., Tai G. Selective infection of astrocytes in human glial cell cultures by rubella virus. Lab. Investig. 1995, 72(3):334-340.
7. Cooper L.Z., Krugman S. Clinical manifestations of postnatal and congenital rubella. Arch. Ophthalmol. 1967, 77(4):434-439.
8. Cooper L.Z., Green R.H., Krugman S., Giles J.P., Mirick G.S. Neonatal thrombocytopenic purpura and other manifestations of rubella contracted in utero. Am. J. Dis. Child. 1965, 110(4):416-427.
9. Cutts F.T., Vynnycky E. Modelling the incidence of congenital rubella syndrome in developing countries. Int. J. Epidemiol. 1999, 28(6):1176-1184.
10. Deb A., Ubil E. Cardiac fibroblast in development and wound healing. J. Mol. Cell. Cardiol. 2014, 70:47-55.
11. Dietrich J., Blumberg B.M., Roshal M., et al. Infection with an endemic human herpesvirus disrupts critical glial precursor cell properties. J. Neurosci. 2004, 24(20):4875-4883.
12. Driscoll S.G. Histopathology of gestational rubella. Am. J. Dis. Child. 1969, 118(1):49-53.
13. Esterly J.R., Oppenheimer E.H. Pathological lesions due to congenital rubella. Arch. Pathol. 1969, 87(4):380-388.
14. Esterly J.R., Oppenheimer E.H. Intrauterine rubella infection. Perspect. Pediatr. Pathol. 1973, 1:313-338.
15. Feuer R., Mena I., Pagarigan R.R., Harkins S., Hassett D.E., Whitton J.L. Coxsackievirus B3 and the neonatal CNS: the roles of stem cells, developing neurons, and apoptosis in infection, viral dissemination, and disease. Am. J. Pathol. 2003, 163(4):1379-1393.
16. Franklin S.L., Kelley R. Congenital rubella and interstitial pneumonitis. Clin. Pediatr. (Phila.) 2001, 40(2):101-103.
17. Garcia A.G., Marques R.L., Lobato Y.Y., Fonseca M.E., Wigg M.D. Placental pathology in congenital rubella. Placenta 1985, 6(4):281-295.
18. Greaves W.L., Orenstein W.A., Stetler H.C., Preblud S.R., Hinman A.R., Bart K.J. Prevention of rubella transmission in medical facilities. JAMA 1982, 248(7):861-864.
19. de Groot-Mijnes J.D., de Visser L., Rothova A., Schuller M., van Loon A.M., Weersink A.J. Rubella virus is associated with Fuchs heterochromic iridocyclitis. Am J. Ophthalmol. 2006, 141(1):212-214.
20. Hardy J., Monif G., Medearis D., Sever J.L. Postnatal transmission of rubella virus to nurses. JAMA 1965, 191:1034.
21. Horstmann D.M. Rubella: the challenge of its control. J. Infect. Dis. 1971, 123(6):640-654.
22. Janta D., Stanescu A., Lupulescu E., Molnar G., Pistol A. Ongoing rubella outbreak among adolescents in Salaj, Romania, September 2011-January 2012. Euro Surveill. 2012, 17(7).
23. Kemper T.L., Lecours A.R., Gates M.J., Yakovlev P.I. Retardation of the myelo- and cytoarchitectonic maturation of the brain in the congenital rubella syndrome. Res. Publ. Assoc. Res. Nerv. Ment. Dis. 1973, 51:23-62.
24. Lima M.T., Machado R., Javech C., Aguilera A., Cutie E. Histopathological study of human placenta in women infected with rubella virus during pregnancy. Morphol. Embryol. (Bucur.) 1977, 23(4):257-260.
25. Lindquist J.M., Plotkin S.A., Shaw L., Gilden R.V., Williams M.L. Congenital rubella syndrome as a systemic infection. Studies of affected infants born in Philadelphia, U.S.A. Br. Med. J. 1965, 2(5475):1401-1406.
26. Menser M.A., Forrest J.M., Honeyman M.C., Burgess J.A. Letter: Diabetes, HL-A antigens, and congenital rubella. Lancet 1974, 2(7895):1508-1509.
27. Miller E., Cradock-Watson J.E., Pollock T.M. Consequences of confirmed maternal rubella at successive stages of pregnancy. Lancet 1982, 2(8302):781-784.
28. Namuwulya P., Abernathy E., Bukenya H., et al. Phylogenetic analysis of rubella viruses identified in Uganda, 2003-2012. J. Med. Virol. 2014.
29. Nguyen T.V., Pham V.H., Abe K. Pathogenesis of congenital rubella virus infection in human fetuses: viral infection in the ciliary body could play an important role in cataractogenesis. EBioMedicine 2015, 2(1):59-63.
30. Ornoy A., Segal S., Nishmi M., Simcha A., Polishuk W.Z. Fetal and placental pathology in gestational rubella. Am. J. Obstet. Gynecol. 1973, 116(7):949-956.
31. Plotkin S., Reef S., Cooper L., Alford C.A. Rubella. Infectious Diseases of the Fetus and Newborn Infant 2011, 861-898. Elsveier, Philadelphia, PA. J. R, J.P. Klein, C. Wilson, V. Nizet, Y. Maldonato (Eds.).
32. Rawls W.E. Congenital rubella: the significance of virus persistence. Prog. Med. Virol. 1968, 10:238-285.
33. Rawls W.E., Phillips A., Melnick J.L., Desmond M.M. Persistent virus infection in congenital rubella. Arch. Ophthalmol. 1967, 77(4):430-433.
34. Rorke L.B. Nervous system lesions in the congenital rubella syndrome. Arch. Otolaryngol. 1973, 98(4):249-251.
35. Rorke L.B., Spiro A.J. Cerebral lesions in congenital rubella syndrome. J. Pediatr. 1967, 70(2):243-255.
36. Rosenberg H.S., Oppenheimer E.H., Esterly J.R. Congenital rubella syndrome: the late effects and their relation to early lesions. Perspect. Pediatr. Pathol. 1981, 6:183-202.
37. Schiff G.M., Dine M.S. Transmission of rubella from newborns. A controlled study among young adult women and report of an unusual case. Am. J. Dis. Child. 1965, 110(4):447-451.
38. Sheridan M.D. Final report of a prospective study of children whose mothers had rubella in early pregnancy. Br. Med. J. 1964, 2(5408):536-539.
39. Simons E.A., Reef S.E., Cooper L.Z., Zimmerman L., Thompson K.M. Systematic review of the manifestations of congenital rubella syndrome in infants and characterization of disability-adjusted life years (DALYs). Risk Anal. 2014.
40. Singer D.B., Rudolph A.J., Rosenberg H.S., Rawls W.E., Boniuk M. Pathology of the congenital rubella syndrome. J. Pediatr. 1967, 71(5):665-675.
41. Standardization of the nomenclature for genetic characteristics of wild-type rubella viruses Wkly Epidemiol. Rec. 2005, 80(14):126-132.
42. Toizumi M., Motomura H., Vo H.M., et al. Mortality associated with pulmonary hypertension in congenital rubella syndrome. Pediatrics 2014.
43. Tondury G., Smith D.W. Fetal rubella pathology. J. Pediatr. 1966, 68(6):867-879.
44. Townsend J.J., Wolinsky J.S., Baringer J.R. The neuropathology of progressive rubella panencephalitis of late onset. Brain 1976, 99(1):81-90.
45. Tsutsui Y., Kosugi I., Kawasaki H., et al. Roles of neural stem progenitor cells in cytomegalovirus infection of the brain in mouse models. Pathol. Int. 2008, 58(5):257-267.
46. Winchester S.A., Varga Z., Parmar D., Brown K.E. Persistent intraocular rubella infection in a patient with Fuchs' uveitis and congenital rubella syndrome. J. Clin. Microbiol. 2013, 51(5):1622-1624.
47. Woods W.A., Johnson R.T., Hostetler D.D., Lepow M.L., Robbins F.C. Immunofluorescent studies on rubella-infected tissue cultures and human tissues. J. Immunol. 1966, 96(2):253-260.