KatG and KatE confer Acinetobacter resistance to hydrogen peroxide but sensitize bacteria to killing by phagocytic respiratory burst

Life Sciences

Volumn 148, Issue , 2016, Pages 31-40

  Sun, Daqing ^a,b   Crowell, Sara A ^a   Harding, Christian M ^a   De Silva, P Malaka ^c   Harrison, Alistair ^a,d   Fernando, Dinesh M ^c   Mason, Kevin M ^a,d   Santana, Estevan ^a   Loewen, Peter C ^c   Kumar, Ayush ^c   Liu, Yusen ^a,d  

^a THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b THE SECOND HOSPITAL OF SHANDONG UNIVERSITY   (China)

^c UNIVERSITY OF MANITOBA   (Canada)

^d THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Abbreviations ACB Acinetobacter calcoaceticus baumannii; ICU intensive care unit; kat catalase; MOI multiplicity of infection; OD optical density; ROS reactive oxygen species; WT wildtype

Indexed keywords

BACTERIAL PROTEIN; CATALASE; HYDROGEN PEROXIDE; KATE PROTEIN; KATG PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ESCHERICHIA COLI PROTEIN; HYDROPEROXIDASE II; KATG PROTEIN, E COLI;

ACINETOBACTER; ACINETOBACTER BAUMANNII; ACINETOBACTER NOSOCOMIALIS; ARTICLE; BACTERIAL VIRULENCE; CHEMOLUMINESCENCE; ENZYME ACTIVITY; GALLERIA MELLONELLA; GENE EXPRESSION; NEUTROPHIL; NONHUMAN; PHAGOCYTE; PHAGOCYTOSIS; RESPIRATORY BURST; ANIMAL; ANTIBIOTIC RESISTANCE; C3H MOUSE; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY;

ACINETOBACTER; ANIMALS; CATALASE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI PROTEINS; HYDROGEN PEROXIDE; MICE; MICE, INBRED C3H; PHAGOCYTES; RESPIRATORY BURST;

EID: 84958763954     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2016.02.015     Document Type: Article

References (43)

1. Association for Professionals in Infection Control and Epidemiology Guide to the Elimination of Multidrug-resistant Acinetobacter baumannii Transmission in Healthcare Settings 2010 APIC Washington, DC
2. H.M. Babcock, J.E. Zack, T. Garrison, E. Trovillion, M.H. Kollef, and V.J. Fraser Ventilator-associated pneumonia in a multi-hospital system: differences in microbiology by location Infect. Control Hosp. Epidemiol. 24 11 2003 853 858
3. E. Bergogne-Berezin, and K.J. Towner Acinetobacter spp. as nosocomial pathogens: microbiological, clinical, and epidemiological features Clin. Microbiol. Rev. 9 2 1996 148 165
4. J.H. Calhoun, C.K. Murray, and M.M. Manring Multidrug-resistant organisms in military wounds from Iraq and Afghanistan Clin. Orthop. Relat. Res. 466 6 2008 1356 1362
5. M.D. Carruthers, C.M. Harding, B.D. Baker, R.A. Bonomo, K.M. Hujer, P.N.·. Rather, and R.S. Munson Jr. Draft genome sequence of the clinical isolate Acinetobacter nosocomialis strain M2 Genome Announc. 1 6 2013
6. Centers for Disease Control and Prevention (CDC) Acinetobacter baumannii infections among patients at military medical facilities treating injured U.S. service members, 2002-2004 MMWR Morb. Mortal. Wkly Rep. 45 53 2004 1063 1066
7. A. Chmielarczyk, P.G. Higgins, J. Wojkowska-Mach, E. Synowiec, E. Zander, D. Romaniszyn, T. Gosiewski, H. Seifert, P. Heczko, and M. Bulanda Control of an outbreak of Acinetobacter baumannii infections using vaporized hydrogen peroxide J. Hosp. Infect. 81 4 2012 239 245
8. K.A. Davis, K.A. Moran, C.K. McAllister, and P.J. Gray Multidrug-resistant Acinetobacter extremity infections in soldiers Emerg. Infect. Dis. 11 8 2005 1218 1224
9. M.C. Dinauer Chronic granulomatous disease and other disorders of phagocyte function Hematology. Am. Soc. Hematol. Educ. Program. 2005 89 95
10. W.J. Frazier, X. Wang, L.M. Wancket, X.A. Li, X. Meng, L.D. Nelin, A.C. Cato, and Y. Liu Increased inflammation, impaired bacterial clearance, and metabolic disruption after gram-negative sepsis in Mkp-1-deficient mice J. Immunol. 183 11 2009 7411 7419
11. L.A. Gallagher, E. Ramage, E.J. Weiss, M. Radey, H.S. Hayden, K.G. Held, H.K. Huse, D.V. Zurawski, M.J. Brittnacher, and C. Manoil Resources for genetic and genomic analysis of emerging pathogen Acinetobacter baumannii J. Bacteriol. 197 12 2015 2027 2035
12. R.H. Glew, R.C.·. Moellering Jr., and L.J. Kunz Infections with Acinetobacter calcoaceticus (Herellea vaginicola): clinical and laboratory studies Medicine (Baltimore) 56 2 1977 79 97
13. C.M. Harding, E.N. Tracy, M.D. Carruthers, P.N. Rather, L.A. Actis, and R.S. Munson Jr. Acinetobacter baumannii strain M2 produces type IV pili which play a role in natural transformation and twitching motility but not surface-associated motility MBio. 4 4 2013
14. A. Harrison, E.A. Santana, B.R. Szelestey, D.E. Newsom, P. White, and K.M. Mason Ferric uptake regulator and its role in the pathogenesis of nontypeable Haemophilus influenzae Infect. Immun. 81 4 2013 1221 1233
15. A. Hillar, B. Peters, R. Pauls, A. Loboda, H. Zhang, A.G. Mauk, and P.C. Loewen Modulation of the activities of catalase-peroxidase HPI of Escherichia coli by site-directed mutagenesis Biochemistry (Mosc) 39 19 2000 5868 5875
16. A.C. Jacobs, M.G. Thompson, C.C. Black, J.L. Kessler, L.P. Clark, C.N. McQueary, H.Y. Gancz, B.W. Corey, J.K. Moon, Y. Si, M.T. Owen, J.D. Hallock, Y.I. Kwak, A. Summers, C.Z. Li, D.A. Rasko, W.F. Penwell, C.L. Honnold, M.C. Wise, P.E. Waterman, E.P. Lesho, R.L. Stewart, L.A. Actis, T.J. Palys, D.W. Craft, and D.V. Zurawski AB5075, a highly virulent isolate of Acinetobacter baumannii, as a model strain for the evaluation of pathogenesis and antimicrobial treatments MBio. 5 3 2014 e01076-14
17. Klebanoff S.J., and Clark R.A. The Neutrophil: Function and Clinical Disorders 1978 North-Holland Publishing Company Amsterdam
18. Klenk H., Gotz P.H., Siegmeier R., and Mayr W. "Peroxy Compounds, Organic", Ullmann's Encyclopedia of Industrial Chemistry 2005 Wiley-VCH Weinheim
19. T.H. Koh, T.T. Tan, C.T. Khoo, S.Y. Ng, T.Y. Tan, L.Y. Hsu, E.E. Ooi, T.J. Van Der Reijden, and L. Dijkshoorn Acinetobacter calcoaceticus-Acinetobacter baumannii complex species in clinical specimens in Singapore Epidemiol. Infect. 140 3 2012 535 538
20. E. Linley, S.P. Denyer, G. McDonnell, C. Simons, and J.Y. Maillard Use of hydrogen peroxide as a biocide: new consideration of its mechanisms of biocidal action J. Antimicrob. Chemother. 67 7 2012 1589 1596
21. P. Loewen Probing the structure of catalase HPII of Escherichia coli-a review Gene 179 1 1996 39 44
22. P.C. Loewen, J. Switala, and B.L. Triggs-Raine Catalases HPI and HPII in Escherichia coli are induced independently Arch. Biochem. Biophys. 243 1 1985 144 149
23. P.C. Loewen, and B.L. Triggs Genetic mapping of katF, a locus that with katE affects the synthesis of a second catalase species in Escherichia coli J. Bacteriol. 160 2 1984 668 675
24. V. Manchanda, S. Sanchaita, and N. Singh Multidrug resistant Acinetobacter J. Global Infect. Dis. 2 3 2010 291 304
25. G.L. Mandell Catalase, superoxide dismutase, and virulence of Staphylococcus aureus. In vitro and in vivo studies with emphasis on staphylococcal-leukocyte interaction J. Clin. Invest. 55 3 1975 561 566
26. L.L. Maragakis, and T.M. Perl Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options Clin. Infect. Dis. 46 8 2008 1254 1263
27. C. Michan, M. Manchado, G. Dorado, and C. Pueyo In vivo transcription of the Escherichia coli oxyR regulon as a function of growth phase and in response to oxidative stress J. Bacteriol. 181 9 1999 2759 2764
28. M.R. Mulvey, J. Switala, A. Borys, and P.C. Loewen Regulation of transcription of katE and katF in Escherichia coli J. Bacteriol. 172 12 1990 6713 6720
29. C. Nathan, and A. Cunningham-Bussel Beyond oxidative stress: an immunologist's guide to reactive oxygen species Nat. Rev. Immunol. 13 5 2013 349 361
30. A. Nemec, L. Krizova, M. Maixnerova, T.J. Van Der Reijden, P. Deschaght, V. Passet, M. Vaneechoutte, S. Brisse, and L. Dijkshoorn Genotypic and phenotypic characterization of the Acinetobacter calcoaceticus-Acinetobacter baumannii complex with the proposal of Acinetobacter pittii sp. nov. (formerly Acinetobacter genomic species 3) and Acinetobacter nosocomialis sp. nov. (formerly Acinetobacter genomic species 13TU) Res. Microbiol. 162 4 2011 393 404
31. A.Y. Peleg, H. Seifert, and D.L. Paterson Acinetobacter baumannii: emergence of a successful pathogen Clin. Microbiol. Rev. 21 3 2008 538 582
32. F. Perez, A.M. Hujer, K.M. Hujer, B.K. Decker, P.N. Rather, and R.A. Bonomo Global challenge of multidrug-resistant Acinetobacter baumannii Antimicrob. Agents Chemother. 51 10 2007 3471 3484
33. A. Ray, F. Perez, A.M. Beltramini, M. Jakubowycz, P. Dimick, M.R. Jacobs, K. Roman, R.A. Bonomo, and R.A. Salata Use of vaporized hydrogen peroxide decontamination during an outbreak of multidrug-resistant Acinetobacter baumannii infection at a long-term acute care hospital Infect. Control Hosp. Epidemiol. 31 12 2010 1236 1241
34. T. Rebmann, and P.A. Rosenbaum Preventing the transmission of multidrug-resistant Acinetobacter baumannii: an executive summary of the association for professionals in infection control and epidemiology's elimination guide Am. J. Infect. Control 39 5 2011 439 441
35. M. Rorth, and P.K. Jensen Determination of catalase activity by means of the Clark oxygen electrode Biochim. Biophys. Acta 139 1 1967 171 173
36. P. Scott, G. Deye, A. Srinivasan, C. Murray, K. Moran, E. Hulten, J. Fishbain, D. Craft, S. Riddell, L. Lindler, J. Mancuso, E. Milstrey, C.T. Bautista, J. Patel, A. Ewell, T. Hamilton, C. Gaddy, M. Tenney, G. Christopher, K. Petersen, T. Endy, and B. Petruccelli An outbreak of multidrug-resistant Acinetobacter baumannii-calcoaceticus complex infection in the US military health care system associated with military operations in Iraq Clin. Infect. Dis. 44 12 2007 1577 1584
37. P.J. Sebeny, M.S. Riddle, and K. Petersen Acinetobacter baumannii skin and soft-tissue infection associated with war trauma Clin. Infect. Dis. 47 4 2008 444 449
38. N.C. Soares, M.P. Cabral, C. Gayoso, S. Mallo, P. Rodriguez-Velo, E. Fernandez-Moreira, and G. Bou Associating growth-phase-related changes in the proteome of Acinetobacter baumannii with increased resistance to oxidative stress J. Proteome Res. 9 4 2010 1951 1964
39. G. Storz, and J.A. Imlay Oxidative stress Curr. Opin. Microbiol. 2 2 1999 188 194
40. J. Switala, and P.C. Loewen Diversity of properties among catalases Arch. Biochem. Biophys. 401 2 2002 145 154
41. E.L. Thomas, T.W. Milligan, R.E. Joyner, and M.M. Jefferson Antibacterial activity of hydrogen peroxide and the lactoperoxidase-hydrogen peroxide-thiocyanate system against oral streptococci Infect. Immun. 62 2 1994 529 535
42. H. Wisplinghoff, T. Paulus, M. Lugenheim, D. Stefanik, P.G. Higgins, M.B. Edmond, R.P. Wenzel, and H. Seifert Nosocomial bloodstream infections due to Acinetobacter baumannii. Acinetobacter pittii and Acinetobacter nosocomialis in the United States J. Infect. 64 3 2012 282 290
43. J. Yan, X. Meng, L.M. Wancket, K. Lintner, L.D. Nelin, B. Chen, K.P. Francis, C.V. Smith, L.K. Rogers, and Y. Liu Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps J. Immunol. 188 5 2012 2316 2327