Global identification of caspase substrates using PROTOMAP (Protein Topography and Migration Analysis Platform)

Methods in Molecular Biology

Volumn 1133, Issue , 2014, Pages 61-70

  Dix, Melissa M ^a   Simon, Gabriel M ^b   Cravatt, Benjamin F ^b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b Abide Therapeutics   (United States)

Author keywords

In gel digestion; Mass spectrometry; Peptograph; PROTOMAP; SDS PAGE; Spectral counting; Substrate identification

Indexed keywords

CASPASE;

APOPTOSIS; ARTICLE; COMPUTER PROGRAM; ENZYME SUBSTRATE; METHODOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN TOPOGRAPHY AND MIGRATION ANALYSIS PLATFORM; PROTEIN TRANSPORT; TANDEM MASS SPECTROMETRY; CONTROLLED STUDY; PROTEIN LOCALIZATION; PROTEIN PROCESSING;

EID: 84958740373     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4939-357-3_3     Document Type: Article

References (3)

1. Dix MM, Simon GM, Cravatt BF (2008) Global mapping of the topography and magnitude of proteolytic events in apoptosis. Cell 134:679-691
2. Simon GM, Dix MM, Cravatt BF (2009) Comparative assessment of large-scale proteomic studies of apoptotic proteolysis. ACS Chem Biol 4:401-408
3. Cociorva D, Tabb DL, Yates JR (2006) Validation of tandem mass spectrometry database search results using DTASelect. Curr Protoc Bioinformatics 13.4.1-13.4.14, supplement 16, Johnwiley and Sons