The curious case of the 1960 Nobel Prize to Burnet and Medawar

Immunology

Volumn 147, Issue 3, 2016, Pages 269-274

  Silverstein, Arthur M ^a  

^a Johns Hopkins Institute of the History of Medicine   (United States)

Author keywords

Burnet; Medawar; Nobel Prize; Tolerance; Transplantation

Indexed keywords

ANTIBODY; ANTIGEN; PNEUMOCOCCUS POLYSACCHARIDE;

ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNE DISEASE; AWARDS AND PRIZES; BOVINE; CELLULAR IMMUNITY; CHIMERA; HUMAN; HYPERSENSITIVITY; IMMUNOLOGICAL TOLERANCE; IMMUNOPATHOLOGY; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEDICAL LITERATURE; NONHUMAN; PRIORITY JOURNAL; TRANSPLANTATION TOLERANCE; HISTORY; IMMUNOLOGY;

ALLERGY AND IMMUNOLOGY; HISTORY, 20TH CENTURY; IMMUNE TOLERANCE; NOBEL PRIZE;

EID: 84958683122     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12558     Document Type: Article

References (53)

1. Burnet FM. The Production of Antibodies. New York: Macmillan, 1941.
2. Burnet FM, Fenner F. The Production of Antibodies, 2nd edn. New York: Macmillan, 1949.
3. Owen RD. Immunogenetic consequences of vascular anastomosis between bovine twins. Science 1945; 102:400-1.
4. Traub E. Factors influencing the persistence of choriomeningitis virus in the blood of mice after clinical recovery. J Exp Med 1936; 64:136; 1938; 68:229; 1939; 69:801.
5. Norrby E. Nobel Prizes and Nature's Surprises. Singapore: World Scientific, 2013: 48-9.
6. Billingham RE, Brent L, Medawar PB "Actively acquired tolerance" of foreign cells. Nature (London) 1953; 172:603-6 (It may be noted that Medawar, as lab chief, always insisted that all authors be listed in alphabetical order).
7. Billingham RE, Lampkin GH, Medawar PB, Williams HL. Studies in tissue homotransplantation in cattle. Heredity 1951; 5:379.
8. Billingham RE, Brent L, Medawar PB. Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance. Philos Trans R Soc Lond B Biol Sci 1956; 239:357.
9. Silverstein AM. A History of Immunology, 2nd edn. New York: Elsevier, 2009.
10. Burnet FM. Enzyme Antigen and Virus. Cambridge: Cambridge University Press, 1956.
11. Talmage DW. Immunological specificity, unique combinations of selected natural globulins provide an alternative to the classical concept. Annu Rev Med 1957; 8:239.
12. Talmage D. Immunological specificity; an alternative to the classical concept. Science 1959; 129:1643.
13. Lederberg J. Genes and antibodies. Science 1959; 129:1649.
14. Burnet FM. The Clonal Selection Theory of Acquired Immunity. Nashville, Vanderbilt University Press, 1959.
15. Burnet FM. Cellular Immunology. Cambridge: Cambridge University Press, 1969.
16. Burnet FM. Self and Not Self. Melbourne: Melbourne University Press, 1969.
17. Medawar PB. The immunology of transplantation. Harvey Lect (New York, Academic Press) 1958; 44:691.
18. Billingham RE, Brent L, Medawar PB. Acquired tolerance of skin homografts. Ann N Y Acad Sci 1955; 59:409.
19. Woodruff MFA. Postpartum induction of tolerance to homologous skin in rats. Ann N Y Acad Sci 1957; 64:792.
20. Cohn M. The problem of specific inhibition of antibody synthesis in adult animals by immunization of embryos. Ann N Y Acad Sci 1957; 64:859.
21. A discussion meeting on tolerance. Proc Roy Soc B 1956; 146:1-92.
22. Grabar P, Eyquem A, eds. Immunopathologie; Clinique et Experimentale. Paris, Flammarion, 1959.
23. Grabar P, Miescher P, eds. Immunopathology-Immunopathologie. Basel: Benno Schwabe, 1959.
24. Shaffer JH, LoGrippo GA, Chase MW, eds. Mechanisms of hypersensitivity, Henry Ford Hospital International Symposium, Boston, Little Brown, 1959.
25. Brent L. Transplantation immunity and hypersensitivity. In: Mechanisms of Hypersensitivity. ref. 25:555-68.
26. Lawrence HS, ed. Cellular and Humoral Aspects of Hypersensitivity States. New York: Hoeber-Harper, 1959.
27. Medawar PB. Reactions to homologous tissue antigens in relation to hypersensitivity. In: Cellular and Humoral Aspects of Hypersensitivity States. ref. 27:504-34.
28. Burnet FM. Immunity as an aspect of general biology. In: Holub M, Jarošková L, eds. Mechanisms of Antibody Formation. Prague, Czech Academy of Science, 1960:15-21.
29. Smith RT. Studies on the mechanism of immune tolerance. In: Mechanisms of Antibody Formation. ref. 29:313-28.
30. Medawar PB. Nobel Lecture. Science 1961; 133:303.
31. Burnet FM. Nobel Lecture. Science 1961; 133:307.
32. Hašek M, Lengerová A, Hraba T. Transplantation immunity and tolerance. Adv Immunol 1961; 1:1.
33. Hašek M. Parabiosis of birds during embryonic development. Czechosl Biol 1953; 2:265.
34. Brent L. A History of Transplantation Immunology. San Diego: Academic Press, 1997: 192-5.
35. Smith RT. Immunological tolerance of nonliving antigens. Adv Immunol 1961; 1:67.
36. Humphrey JH, White RG. Immunology for Students of Medicine. Philadelphia: Davis, 1964.
37. Samter M, Alexander HL, eds. Immunological Diseases. Boston, Little Brown, 1965.
38. Antibodies. Cold Spring Harb Symp Quant Biol vol. 32, 1967.
39. Klein J. Immunology, the Science of Self-Nonself Discrimination. New York: Wiley, 1982.
40. Petrov RV. Ya Ily Nye Ya (Me or Not Me). Moscow, Mir, 1983; English edition 1987.
41. Clark WR. In Defense of Self: How the immune system really works. New York: Oxford, 2008.
42. Bernard J, Bessis M, Debru C. Soi et Nonsoi (Self and Nonself). Paris: Seuil, 1990.
43. Langman RE, ed. Self-nonself discrimination revisited, special issue. Sem Immunol 2000; 12:159-344.
44. Carosella E, Pradeu T. L'identité, la Part de l'Autre: Immunologie et philosophie (Identity, the role of the other). Paris: Odile Jacob, 2010.
45. Tauber AI. The Immune Self: Theory or Metaphor. Cambridge: Cambridge University Press, 1994.
46. Cohen I. Tending Adam's Garden: Evolving the cognitive immune self. San Diego: Academic Press, 2004.
47. Silverstein AM, Rose NR. On the mystique of the immunological self. Immunol Rev 1997; 159:197-206.
48. Pradeu T. The Limits of the Self: Immunology and Biological Identity. New York: Oxford, 2012.
49. Bretscher P, Cohn M. A theory of self-nonself discrimination. Science 1970; 169:1042-9.
50. Brent L. Presidential Address. Transplant Proc 1977; 9:1343.
51. Brent L. A History of Transplantation Immunology. ref. 35: pp. 230-305.
52. Norrby E. Nobel Prizes and Nature's Surprises. ref. 5. While the data from the Nobel Archives are derived from Norrby's book (and from Prof. Norrby's personal communications), all suggestions and conclusions herein are my own.
53. Burnet FM. A modification of Jerne's theory of antibody production using the concept of clonal selection. Aust J Sci 1957; 20:67.