Genome-Wide polyadenylation maps reveal dynamic mRNA 3′-End formation in the failing human heart

Circulation Research

Volumn 118, Issue 3, 2016, Pages 433-438

  Creemers, Esther E ^a   Bawazeer, Amira ^a   Van Ugalde, Alejandro P ^b   Van Deutekom, Hanneke W M ^a   Der Made, Ingeborg ^a   De Groot, Nina E ^a   Adriaens, Michiel E ^a   Cook, Stuart A ^c   Van Bezzina, Connie R ^a   Hubner, Norbert ^d   Der Velden, Jolanda ^e   Elkon, Ran ^b   Agami, Reuven ^b   Pinto, Yigal M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^d MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Cardiomyopathies; Gene expression regulation; Heart failure; Humans; Polyadenylation; Untranslated regions

Indexed keywords

ACTIN; CALCINEURIN; CALCINEURIN 1; CARDIAC ACTIN; CDC42 EFFECTOR PROTEIN 3; PHOSPHATIDYLINOSITOL GLYCAN K; POLYADENYLIC ACID BINDING PROTEIN; PROTEIN CDC42; SMALL EDRK RICH FACTOR 2; UNCLASSIFIED DRUG; WEE1 G2 CHECKPOINT KINASE; 3' UNTRANSLATED REGION; MESSENGER RNA; PABPN1 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ACTIN BINDING; ALTERNATIVE CLEAVAGE AND POLYADENYLATION; ARTICLE; CLEAVAGE SITE; CLINICAL ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; CYTOSKELETON; DOWN REGULATION; GENE EXPRESSION; HEART; HEART FAILURE; HUMAN; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN BINDING; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA BINDING; RNA CLEAVAGE; RNA SEQUENCE; STOP CODON; UPREGULATION; WESTERN BLOTTING; ADULT; AGED; CASE CONTROL STUDY; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MALE; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PROCEDURES;

3' UNTRANSLATED REGIONS; ADULT; AGED; BASE SEQUENCE; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME-WIDE ASSOCIATION STUDY; HEART FAILURE; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; POLY(A)-BINDING PROTEIN I; POLYADENYLATION; RNA, MESSENGER;

EID: 84958656746     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.115.307082     Document Type: Article

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