Centrifugal Partition Chromatography for Lipophilicity Measurements

Lipophilicity in Drug Action and Toxicology

Volumn 4, Issue , 2008, Pages 89-107

  Tsai, Ruey Shiuan ^a   Lisa, Giuseppe ^a   Carrupt, Pierre Alain ^a   Testa, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

Chloroform; Di N butyl ether; Hydrostatic equilibrium systems; Lipophilicity; Structure activity relationships

Indexed keywords

CHLORINE COMPOUNDS;

BUTYL ETHER; CENTRIFUGAL PARTITION CHROMATOGRAPHY; HYDROSTATIC EQUILIBRIUM; LIPOPHILICITY; LIPOPHILICITY MEASUREMENT; STRUCTURE ACTIVITY RELATIONSHIPS;

LIQUID CHROMATOGRAPHY;

EID: 84958646408     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527614998.ch6     Document Type: Chapter

References (34)

1. Hansch, C., and Leo, A., Substituent Constants for Correlation Analysis in Chemistry and Biology. Wiley: New York 1979
2. Rekker, R. F., The Hydrophobic Fragmental Constant. Elsevier: Amsterdam 1977
3. Hansch, C., Vittoria, A., Silipo, C., and Jow, P. Y. C., J. Med. Chem. 18, 546-548 (1975)
4. Young, R. C., Mitchell, R. C., Brown, T.H., Ganellin, C. R., Griffiths, R., Jones, M., Rana, K. K., Saunders, D., Smith, I. R., Nerina, E. S., and Wilks, T. J. J. Med. Chem. 31, 656-671 (1988)
5. Burton, P. S., Conradi, R. A., Hilgers, A. R., Ho, N.F.H., and Maggiora, L. L., J. Controlled Release 19, 87-98 (1992)
6. El Tayar, N., Tsai, R.-S., Testa, B., Carrupt, P.-A., Hansch, C., and Leo, A. J. Pharm. Sci. 80, 744-749 (1991)
7. Leo, A., Hansch, C., and Elkins, D., Chem. Rev. 71, 525-555 (1971)
8. Dearden, J. C., and Bresnen, G. M., Quant. Struc.-Act. Relat. 7, 133-144 (1988)
9. Lambert, W. J., J. Chromatogr. 656, 469-484 (1993)
10. El Tayar, N., Tsai, R.-S., Vallat, P., Altomare, C., and Testa, B., J. Chromatogr. 556, 181-194 (1991)
11. Martin, A. J. P., and Synge, R. L. M., Biochem. J., 35, 1358-1368 (1941)
12. Horváth, C., and Lipsky, S. R., Nature 211, 748-749 (1966)
13. Ito, Y., Weinstein, M. A., Aoki, I., Harada, R., Kimura, E., and Nunogaki, K., Nature 212, 985-987 (1966)
14. Terada, H., Kosuge, Y., Murayama, W., Nakaya, N., Nunogaki, Y. and Nunogaki, K.-I., J. Chromatogr. 400, 343-351 (1987)
15. Berthod, A., Han, Y. I., and Armstrong, D. W., J. Liq. Chromatogr. 11, 1441-1456 (1988)
16. Et Tayar, N., Marston, A., Bechalany, A., Hostettmann, K., and Testa, B., J. Chromatogr. 469, 91-99 (1989)
17. Vallat, P., El Tayar, N., Testa, B., Slacanin, I., Marston, A., and Hostettmann, K., J. Chromatogr. 504, 411-419 (1990)
18. Tsai, R.-S., Carrupt, P.-A., and Testa, B., Measurement of partition coefficient using centrifugal chromatography method development and application to the determination of solute properties. In: Countercurrent Chromatography. Conway, W. D. and Petroski, R. (Eds.). ACS Symposium Series 593, American Chemical Society: Washington, DC; 143-154 (1995)
19. El Tayar, N., Tsai, R.-S., Testa, B., Carrupt, P. A., and Leo, A., J. Pharm. Sci. 80, 590-598 (1991)
20. Tanimura, T., Pisano, J. J., Ito, Y., and Bowman, R. L., Science 169, 54-56 (1970)
21. Ito, Y., CRC Crit. Rev. Anal. Chem. 17, 65-148 (1986)
22. Foucault, A. P., (Ed.). Centrifugal Partition Chromatography. Marcel Dekker: New York 1994
23. Conway, W. D., and Ito, Y., Abstract of the 1984 Pittsburgh Conference and Exposition on Analytical Chemistry and Applied Spectroscopy, 471 (1984)
24. Hansch, C., and Leo, A., The Pomona College Medicinal Chemistry Project. Version 3.55, Clarement 1993
25. Zografi, G., and Yalkowsky, S. H., J. Pharm. Sci. 63, 1533-1536 (1974)
26. Ter Laak, T., Tsai, R.-S., Donné-Op den Kelder, G. M., Carrupt, P.-A., Testa, B., and Tim-merman, H., Eur. J. Pharm. Sci. 2, 373-384 (1994)
27. Seiler, P., Eur. J. Med. Chem. 9, 473-479 (1974)
28. Fan, W., A New Experimental Hydration Parameter: the Water-Dragging Effect. PhD Thesis, Université de Lausanne, Lausanne 1992
29. Rose, G. J., Gierash, L. M., and Smith, J. A., Adv. Protein Chem. 37, 1-109 (1985)
30. Abraham, D. J., and Leo, A., Proteins: Structure, Function, and Genetics 2, 130-152 (1987)
31. Tsai, R.-S., Testa, B., El Tayar, N., and Carrupt, P.-A., J. Chem. Soc. Perkins Trans. II, 1797-1802 (1991)
32. Carrupt, P.-A., Tsai, R.-S., El Tayar, N., Testa, B., de Paulis, T., and Högberg, T., Helv. Chim. Acta 74, 956-968 (1991)
33. Tsai, R.-S., Carrupt, P.-A., Testa, B., Gaillard, P., El Tayar, N., and Högberg, T., J. Med. Chem. 36, 196-204 (1993)
34. Berthod, A., Menges, R. A., and Armstrong, D. W., J. Liq. Chromatogr. 16, 2769-2785 (1992)