Lipophilicity Descriptors for Structure-Property Correlation Studies: Overview of Experimental and Theoretical Methods and a Benchmark of log P Calculations

Lipophilicity in Drug Action and Toxicology

Volumn 4, Issue , 2008, Pages 401-418

  van de Waterbeemd, Han ^a   Mannhold, Raimund ^b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Algorithm; Chromatography; Molecular properties; Octanol; Rekker fragmental constant

Indexed keywords

CHROMATOGRAPHY;

DESCRIPTORS; LIPOPHILICITY; MOLECULAR PROPERTIES; OCTANOL; REKKER FRAGMENTAL CONSTANT; STRUCTURE-PROPERTY CORRELATION; THEORETICAL METHODS;

ALGORITHMS;

EID: 84958605951     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527614998.ch23     Document Type: Chapter

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