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Volumn , Issue , 2007, Pages 173-201

Combinatorial library based on the one-bead-one-compound concept

Author keywords

[No Author keywords available]

Indexed keywords

COMBINATORIAL LIBRARY;

EID: 84958239785     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527614912.ch06     Document Type: Chapter
Times cited : (7)

References (96)
  • 2
    • 0025004285 scopus 로고
    • Random peptide libraries: Source of specific protein binding molecules
    • J. J. Devlin, L. C. Panganiban, P. E. Devlin, Random peptide libraries: source of specific protein binding molecules. Science 1990, 249, 404-406.
    • (1990) Science , vol.249 , pp. 404-406
    • Devlin, J.J.1    Panganiban, L.C.2    Devlin, P.E.3
  • 3
    • 0025112794 scopus 로고
    • Searching for peptide ligands with an epitope library
    • J. K. Scott, G. P. Smith, Searching for peptide ligands with an epitope library. Science 1990, 249, 386-390.
    • (1990) Science , vol.249 , pp. 386-390
    • Scott, J.K.1    Smith, G.P.2
  • 4
    • 0026411004 scopus 로고
    • Selection of antibody ligands from a large library of oligopeptides expressed on a multivalent exposition vector
    • F. Felici, L. Castagnoli, A. Musacchio, R. Japelli, G. Cesareni, Selection of antibody ligands from a large library of oligopeptides expressed on a multivalent exposition vector. J. Mol. Biol. 1991, 222, 301-310.
    • (1991) J. Mol. Biol. , vol.222 , pp. 301-310
    • Felici, F.1    Castagnoli, L.2    Musacchio, A.3    Japelli, R.4    Cesareni, G.5
  • 5
    • 0026546880 scopus 로고
    • Screening for receptor ligands using large libraries of peptides linked to the C terminus of the lac repressor
    • M. G. Cull, J. F. Miller, P. J. Schatz, Screening for receptor ligands using large libraries of peptides linked to the C terminus of the lac repressor. Proc. Natl. Acad. Sci. USA 1992, 89, 1865-1869.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 1865-1869
    • Cull, M.G.1    Miller, J.F.2    Schatz, P.J.3
  • 6
    • 8244230028 scopus 로고
    • Cell-free synthesis and isolation of novel genes and polypeptides
    • International Patent Application WO 91/05058
    • K. Kawasaki, Cell-free synthesis and isolation of novel genes and polypeptides. International Patent Application WO 91/05058 1991.
    • (1991)
    • Kawasaki, K.1
  • 7
    • 0022646579 scopus 로고
    • A priori delineation of a peptide which mimics a discontinuous antigenic determinant
    • M. H. Geysen, H. M. Rodda, T. J. Mason, A priori delineation of a peptide which mimics a discontinuous antigenic determinant. Mol. Immunol. 1986, 23, 709-715.
    • (1986) Mol. Immunol. , vol.23 , pp. 709-715
    • Geysen, M.H.1    Rodda, H.M.2    Mason, T.J.3
  • 8
    • 0026419319 scopus 로고
    • Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery
    • (7 November)
    • R. A. Houghten, C. Pinilla, S. E. Blondelle, J. R. Appel, C. T. Dooley, J. H. Cuervo, Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature (London) 1991, 354, (7 November), 84-86.
    • (1991) Nature (London) , vol.354 , pp. 84-86
    • Houghten, R.A.1    Pinilla, C.2    Blondelle, S.E.3    Appel, J.R.4    Dooley, C.T.5    Cuervo, J.H.6
  • 9
    • 0026345157 scopus 로고
    • The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures
    • R. A. Owens, P. D. Gesellchen, B. J. Houchins, R. D. DiMarchi, The rapid identification of HIV protease inhibitors through the synthesis and screening of defined peptide mixtures. Biochem. Biophys. Res. Commun. 1991, 181, 402-408.
    • (1991) Biochem. Biophys. Res. Commun. , vol.181 , pp. 402-408
    • Owens, R.A.1    Gesellchen, P.D.2    Houchins, B.J.3    DiMarchi, R.D.4
  • 10
    • 0026952289 scopus 로고
    • Evaluation of peptide libraries: An iterative strategy to analyze the reactivity of peptide mixtures with antibodies
    • J. Blake, L. Litzi-Davis, Evaluation of peptide libraries: an iterative strategy to analyze the reactivity of peptide mixtures with antibodies. Bioconjugate Chem. 1992,3, 510-513.
    • (1992) Bioconjugate Chem. , vol.3 , pp. 510-513
    • Blake, J.1    Litzi-Davis, L.2
  • 12
    • 0345365241 scopus 로고
    • Spot-synthesis: An easy and flexible tool to study molecular recognition
    • (Ed: R. Epton) Mayflower Worldwide Ltd. Birmingham
    • R. Frank, Spot-synthesis: an easy and flexible tool to study molecular recognition in (Ed: R. Epton) Innovation and Perspectives in Solid Phase Synthesis, Vol. 3, Mayflower Worldwide Ltd. Birmingham 1994, pp. 509-512.
    • (1994) Innovation and Perspectives in Solid Phase Synthesis , vol.3 , pp. 509-512
    • Frank, R.1
  • 13
    • 0027689252 scopus 로고
    • Simultaneous synthesis of peptide libraries on single resin and continuous cellulose membrane supports: Examples for the identification of protein, metal and DNA binding peptide mixtures
    • A. Kramer, R. Volkmer-Engert, R. Malin, U. Reineke, J. Schneider-Mergener, Simultaneous synthesis of peptide libraries on single resin and continuous cellulose membrane supports: examples for the identification of protein, metal and DNA binding peptide mixtures. Pept. Res. 1993, 6, 314-319.
    • (1993) Pept. Res. , vol.6 , pp. 314-319
    • Kramer, A.1    Volkmer-Engert, R.2    Malin, R.3    Reineke, U.4    Schneider-Mergener, J.5
  • 14
    • 0027052983 scopus 로고
    • Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries
    • C. Pinilla, J. R. Appel, P. Blanc, R. A. Houghten, Rapid identification of high affinity peptide ligands using positional scanning synthetic peptide combinatorial libraries. BioTechniques 1992, 13, 901-905.
    • (1992) BioTechniques , vol.13 , pp. 901-905
    • Pinilla, C.1    Appel, J.R.2    Blanc, P.3    Houghten, R.A.4
  • 15
    • 0028067551 scopus 로고
    • Investigation of antigen-antibody interactions using a soluble, non-support-bound synthetic dacapeptide library composed of four trillion (4 x 1012) sequences
    • C. Pinilla, J. R. Appel, R. A. Houghten, Investigation of antigen-antibody interactions using a soluble, non-support-bound synthetic dacapeptide library composed of four trillion (4 x 1012) sequences. Biochem. J. 1994, 301, 847-853.
    • (1994) Biochem. J. , vol.301 , pp. 847-853
    • Pinilla, C.1    Appel, J.R.2    Houghten, R.A.3
  • 16
    • 0026419328 scopus 로고
    • A new type of synthetic peptide library for identifying ligand-binding activity
    • (7 November)
    • K. S. Lam, S. E. Salmon, E. M. Hersh, V. J. Hruby, W. M. Kazmierski, R. J. Knapp, A new type of synthetic peptide library for identifying ligand-binding activity. Nature (London) 1991, 354, (7 November), 82-84.
    • (1991) Nature (London) , vol.354 , pp. 82-84
    • Lam, K.S.1    Salmon, S.E.2    Hersh, E.M.3    Hruby, V.J.4    Kazmierski, W.M.5    Knapp, R.J.6
  • 17
    • 8244253832 scopus 로고
    • Random bio-oligomer library, a method of synthesis thereof and a method of use thereof
    • International Patent WO 91/17823
    • K. S. Lam, S. E. Salmon, V. J. Hruby, E. M. Hersh, Random bio-oligomer library, a method of synthesis thereof and a method of use thereof. International Patent WO 91/178231993.
    • (1993)
    • Lam, K.S.1    Salmon, S.E.2    Hruby, V.J.3    Hersh, E.M.4
  • 18
    • 0001759581 scopus 로고
    • Synthtic receptor for internal residues of a peptide chain. Highly selective binding of (l)X-(l)Pto-(l)X tripeptides
    • A. Borchardt, W. C. Still, Synthtic receptor for internal residues of a peptide chain. Highly selective binding of (l)X-(l)Pto-(l)X tripeptides. J. Am. Chem. Soc. 1994,116, 7467-7468.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 7467-7468
    • Borchardt, A.1    Still, W.C.2
  • 19
    • 0028100318 scopus 로고
    • Peptidosteroidal receptors for opioid peptides. Sequence-selective binding using a synthetic receptor library
    • R. Boyce, G. Li, H. P. Nestler, T. Suenaga, W. C. Still, Peptidosteroidal receptors for opioid peptides. Sequence-selective binding using a synthetic receptor library. J. Am. Chem. Soc. 1994, 116, 7955-7956.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 7955-7956
    • Boyce, R.1    Li, G.2    Nestler, H.P.3    Suenaga, T.4    Still, W.C.5
  • 20
    • 23444457432 scopus 로고
    • A mass spectrometry solution to the address problem of combinational libraries
    • (15 Apr)
    • C. L. Brummel, I. N. W. Lee, Y. Zhou, S. J. Benkovic, N. Winograd, A mass spectrometry solution to the address problem of combinational libraries. Science 1994,264, (15 Apr): 399-402.
    • (1994) Science , vol.264 , pp. 399-402
    • Brummel, C.L.1    Lee, I.N.W.2    Zhou, Y.3    Benkovic, S.J.4    Winograd, N.5
  • 21
    • 3743084024 scopus 로고
    • Analogous organic synthesis of small-compound libraries: validation of combinatorial chemistry in small-molecule synthesis
    • C. Chen, A. L. A. Randall, B. R. Miller, D. A. Jones, M. J. Kurth, Analogous organic synthesis of small-compound libraries: validation of combinatorial chemistry in small-molecule synthesis. J. Am. Chem. Soc. 1994, 116, 2661-2662.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 2661-2662
    • Chen, C.1    Randall, A.L.A.2    Miller, B.R.3    Jones, D.A.4    Kurth, M.J.5
  • 22
    • 0028458139 scopus 로고
    • Self-encoded, highly condensed solid phase-supported peptide library for identification of ligand-specific peptides
    • V. Hornik, E. Hadas, Self-encoded, highly condensed solid phase-supported peptide library for identification of ligand-specific peptides. React. Polym. 1994, 22, 213-220.
    • (1994) React. Polym. , vol.22 , pp. 213-220
    • Hornik, V.1    Hadas, E.2
  • 24
    • 0027603405 scopus 로고
    • Screening of synthetic peptide libraries with radiolabeled acceptor molecules
    • A. Kassarjian, V. Schellenberger, C. W. Turck, Screening of synthetic peptide libraries with radiolabeled acceptor molecules. Pept. Res. 1993, 6, 129-133.
    • (1993) Pept. Res. , vol.6 , pp. 129-133
    • Kassarjian, A.1    Schellenberger, V.2    Turck, C.W.3
  • 25
    • 0028264809 scopus 로고
    • Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endo-protease specificity
    • M. Meldal, I. Svendsen, K. Breddam, I. Auzanneau France, Portion-mixing peptide libraries of quenched fluorogenic substrates for complete subsite mapping of endo-protease specificity. Proc. Natl. Acad. Sci. USA 1994, 91, 3314-3318.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3314-3318
    • Meldal, M.1    Svendsen, I.2    Breddam, K.3    Auzanneau France, I.4
  • 28
    • 0027972778 scopus 로고
    • Matrix-assisted laser desorption ionization for rapid determination of the sequences of biologically active peptides isolated from support-bound combinatorial peptide libraries
    • S. R. Youngquist, G. R. Fuentes, M. P. Lacey, T. Keough, Matrix-assisted laser desorption ionization for rapid determination of the sequences of biologically active peptides isolated from support-bound combinatorial peptide libraries. Rapid Commun. Mass Spectrom. 1994, 8, 77-81.
    • (1994) Rapid Commun. Mass Spectrom. , vol.8 , pp. 77-81
    • Youngquist, S.R.1    Fuentes, G.R.2    Lacey, M.P.3    Keough, T.4
  • 29
    • 0027892193 scopus 로고
    • Biased combinatorial libraries: novel ligands for the SH3 domain of phosphatidylinositol 3-kinase
    • J. K. Chen, W. S. Lane, A. W. Brauer, A. Tanaka, S. L. Schreiber, Biased combinatorial libraries: novel ligands for the SH3 domain of phosphatidylinositol 3-kinase. J. Am. Chem. Soc. 1993, 115, 12591-12592.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 12591-12592
    • Chen, J.K.1    Lane, W.S.2    Brauer, A.W.3    Tanaka, A.4    Schreiber, S.L.5
  • 30
    • 0027962809 scopus 로고
    • Screening synthetic peptide libraries with targets bound to magnetic beads
    • G. Fassina, M. R. Bellitti, G. Cassani, Screening synthetic peptide libraries with targets bound to magnetic beads. Protein Pept. Lett. 1994, 1, 15-18.
    • (1994) Protein Pept. Lett. , vol.1 , pp. 15-18
    • Fassina, G.1    Bellitti, M.R.2    Cassani, G.3
  • 31
    • 0026521405 scopus 로고
    • Identification of highest-affinity ligands by affinity selection from equimolar peptide mixtures generated by robotic synthesis
    • R. N. Zuckermann, M. Kerr, M. A. Siani, S. C. Banville, D. V. Santi, Identification of highest-affinity ligands by affinity selection from equimolar peptide mixtures generated by robotic synthesis. Proc. Natl. Acad. Sci. USA 1992, 89, 4505-4509.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4505-4509
    • Zuckermann, R.N.1    Kerr, M.2    Siani, M.A.3    Banville, S.C.4    Santi, D.V.5
  • 33
    • 0025893762 scopus 로고
    • General method for rapid synthesis of multicomponent peptide mixtures
    • A. Furka, F. Sebestyen, M. Asgedom, G. Dibo, General method for rapid synthesis of multicomponent peptide mixtures. Int. J. Pept. Protein Res. 1991, 37, 487-493.
    • (1991) Int. J. Pept. Protein Res. , vol.37 , pp. 487-493
    • Furka, A.1    Sebestyen, F.2    Asgedom, M.3    Dibo, G.4
  • 40
  • 41
    • 0028109561 scopus 로고
    • All-ro cyclopentane scaffolding for combinatorial solid phase synthesis of small non-peptide compounds
    • M. Paítek, B. Drake, M. Lebl, All-ro cyclopentane scaffolding for combinatorial solid phase synthesis of small non-peptide compounds. Tetrahedron Lett. 1994,35,9169-9172.
    • (1994) Tetrahedron Lett. , vol.35 , pp. 9169-9172
    • Paítek, M.1    Drake, B.2    Lebl, M.3
  • 42
    • 85033302330 scopus 로고
    • Libraries of small compact structures N-acyl-N-alkylamino acids
    • Proceedings of the 23rd European Peptide Symposioum, (Ed: H. S. Maia)
    • Z. Flegelova, V. Krchnaík, N. F. Sepetov, M. Stankova, O. Issakova, D. Cabel, K. S. Lam, M. Lebl, Libraries of small compact structures N-acyl-N-alkylamino acids in Peptides 94, Proceedings of the 23rd European Peptide Symposioum, (Ed: H. S. Maia), 1995, p. 469-470.
    • (1995) Peptides 94 , pp. 469-470
    • Flegelova, Z.1    Krchnaík, V.2    Sepetov, N.F.3    Stankova, M.4    Issakova, O.5    Cabel, D.6    Lam, K.S.7    Lebl, M.8
  • 43
    • 85030305839 scopus 로고
    • Amino-acid like subunits based on iminodiacetic acid and their application in linear and DKP-libraries
    • (Ed: H. S. Maia), Proceedings of the 23rd European Peptide Symposium
    • P. Safar, A. Stierandova, M. Lebl, Amino-acid like subunits based on iminodiacetic acid and their application in linear and DKP-libraries in Peptides 94 (Ed: H. S. Maia), Proceedings of the 23rd European Peptide Symposium, 1994, p. 471-472.
    • (1994) Peptides 94 , pp. 471-472
    • Safar, P.1    Stierandova, A.2    Lebl, M.3
  • 44
    • 0027597947 scopus 로고
    • Peptide-encoding for structure determination of nonsequenceable polymers within libraries synthesized and tested on solid-phase supports
    • V. Nikolaiev, A. Stierandova, V. Krchnaík, B. Seligman, K. S. Lam, S. E. Salmon, M. Lebl, Peptide-encoding for structure determination of nonsequenceable polymers within libraries synthesized and tested on solid-phase supports. Pept. Res. 1993, 6, 161-170.
    • (1993) Pept. Res. , vol.6 , pp. 161-170
    • Nikolaiev, V.1    Stierandova, A.2    Krchnaík, V.3    Seligman, B.4    Lam, K.S.5    Salmon, S.E.6    Lebl, M.7
  • 46
    • 84989568285 scopus 로고
    • Synthetic methods for the implementation of encoded combinatorial chemistry
    • J. Nielsen, R. A. Brenner, K. D. Janda, Synthetic methods for the implementation of encoded combinatorial chemistry. J. Am. Chem. Soc. 1993, 115, 9812-9813.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 9812-9813
    • Nielsen, J.1    Brenner, R.A.2    Janda, K.D.3
  • 47
    • 33751157590 scopus 로고
    • A general method for molecular tagging of encoded combinatorial chemistry libraries
    • H. P. Nestler, P. A. Bartlett, W. C. Still, A general method for molecular tagging of encoded combinatorial chemistry libraries. J. Org. Chem. 1994, 59, 4723-4724.
    • (1994) J. Org. Chem. , vol.59 , pp. 4723-4724
    • Nestler, H.P.1    Bartlett, P.A.2    Still, W.C.3
  • 48
    • 0000772738 scopus 로고
    • Encoded combinatorial peptide libraries containing non-natural amino acids
    • J. M. Kerr, S. C. Banville, R. N. Zuckermann, Encoded combinatorial peptide libraries containing non-natural amino acids. J. Am. Chem. Soc. 1993, 115, 2529-2531.
    • (1993) J. Am. Chem. Soc. , vol.115 , pp. 2529-2531
    • Kerr, J.M.1    Banville, S.C.2    Zuckermann, R.N.3
  • 49
    • 3042872161 scopus 로고
    • Synthetic combinatorial libraries-a new tool for drug design: Methods for identifying the composition of compound from peptide and/or nonpeptide libraries
    • (Eds: M. Z. Atassi, E. Appella), Plenum Publishing
    • M. Lebl, V. Krchnaík, N. F. Sepetov, V. Nikolaev, M. Stankovaí, P. Kocis, M. Paítek, Z. Flegelovaí, R. Ferguson, K. S. Lam, Synthetic combinatorial libraries-a new tool for drug design: methods for identifying the composition of compound from peptide and/or nonpeptide libraries in Methods in Protein Structure Analysis. (Eds: M. Z. Atassi, E. Appella), Plenum Publishing, 1995, pp. 335-342.
    • (1995) Methods in Protein Structure Analysis , pp. 335-342
    • Lebl, M.1    Krchnaík, V.2    Sepetov, N.F.3    Nikolaev, V.4    Stankovaí, M.5    Kocis, P.6    Paítek, M.7    Flegelovaí, Z.8    Ferguson, R.9    Lam, K.S.10
  • 50
    • 0002104206 scopus 로고
    • Novel methodology for differentiation of surface and interior areas of poly(oxyethylene)-polystyrene (POE-PS) supports: applications to library screening procedures
    • (Ed: R. Epton) Mayflower Worldwide Ltd., Birmingham
    • J. Vagner, V. Krchnaík, N. F. Sepetov, P. Strop, K. S. Lam, G. Barany, M. Lebl, Novel methodology for differentiation of surface and interior areas of poly(oxyethylene)-polystyrene (POE-PS) supports: applications to library screening procedures in Innovation and Perspectives in Solid Phase Synthesis (Ed: R. Epton), Vol. 3, Mayflower Worldwide Ltd., Birmingham, 1994, pp. 347-352.
    • (1994) Innovation and Perspectives in Solid Phase Synthesis , vol.3 , pp. 347-352
    • Vagner, J.1    Krchnaík, V.2    Sepetov, N.F.3    Strop, P.4    Lam, K.S.5    Barany, G.6    Lebl, M.7
  • 51
    • 84958271352 scopus 로고
    • New approach in constructing and screening peptide libraries
    • (Ed: H. S. Maia), Proceedings of the 23rd European Peptide Symposium
    • N. F. Septov, V. Krchnaík, M. Stankovaí, K. S. Lam, S. Wade, M. Lebl, New approach in constructing and screening peptide libraries in Peptides 94 (Ed: H. S. Maia), Proceedings of the 23rd European Peptide Symposium 1995, 467-468.
    • (1995) Peptides 94 , pp. 467-468
    • Septov, N.F.1    Krchnaík, V.2    Stankovaí, M.3    Lam, K.S.4    Wade, S.5    Lebl, M.6
  • 52
    • 0029074391 scopus 로고
    • Library of libraries-a new way of screening the structural complexity of randomly synthesized ligands
    • N. F. Sepetov, V. Krchnaík, M. Stankovaí, K. S. Lam, M. Lebl, Library of libraries-a new way of screening the structural complexity of randomly synthesized ligands. Proc. Natl. Acad. Sci. USA 1995, 92, 5426-5430.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 5426-5430
    • Sepetov, N.F.1    Krchnaík, V.2    Stankovaí, M.3    Lam, K.S.4    Lebl, M.5
  • 53
    • 8244232090 scopus 로고
    • Substrate motif identification for posttranslational motifications
    • K. S. Lam, J. Wu, Substrate motif identification for posttranslational motifications. Methods, A Companion to Methods Enzymol. 1994, 6, 401-403.
    • (1994) Methods, A Companion to Methods Enzymol , vol.6 , pp. 401-403
    • Lam, K.S.1    Wu, J.2
  • 54
    • 0028556408 scopus 로고
    • Identifying substrate motifs of protein kinases by a random library approach
    • J. Wu, Q. N. Ma, K. S. Lam, Identifying substrate motifs of protein kinases by a random library approach. Biochemistry 1994, 33, 14825-14833.
    • (1994) Biochemistry , vol.33 , pp. 14825-14833
    • Wu, J.1    Ma, Q.N.2    Lam, K.S.3
  • 55
    • 0027994775 scopus 로고
    • Identification of small peptides that interact specifically with a small organic dye
    • K. S. Lam, Z.-G. Zhao, S. Wade, V. Krchnaík, M. Lebl, Identification of small peptides that interact specifically with a small organic dye. Drug Devel. Res. 1994, 33, 157-160.
    • (1994) Drug Devel. Res. , vol.33 , pp. 157-160
    • Lam, K.S.1    Zhao, Z.-G.2    Wade, S.3    Krchnaík, V.4    Lebl, M.5
  • 57
    • 0028914195 scopus 로고
    • Application of a dual color detection scheme in the screening of a random combinatorial peptide library
    • K. S. Lam, S. Wade, F. Abdul-Latif, M. Lebl, Application of a dual color detection scheme in the screening of a random combinatorial peptide library. J. Immun. Methods 1995, 180, 219-223.
    • (1995) J. Immun. Methods , vol.180 , pp. 219-223
    • Lam, K.S.1    Wade, S.2    Abdul-Latif, F.3    Lebl, M.4
  • 58
    • 8244234626 scopus 로고
    • Screening of completely random one-bead-one-peptide libraries for activities in solution
    • M. Lebl, V. Krchnaík, S. E. Salmon, K. Lam, Screening of completely random one-bead-one-peptide libraries for activities in solution. Methods, A companion to Methods Enzymol. 1994, 6, 381-387.
    • (1994) Methods, A companion to Methods Enzymol , vol.6 , pp. 381-387
    • Lebl, M.1    Krchnaík, V.2    Salmon, S.E.3    Lam, K.4
  • 63
    • 37049102463 scopus 로고
    • Peptide synthesis. Part 1. Preparation and use of polar supports based on poly(dimethylacrylamide)
    • R. Arshady, E. Aetherton, D. L. J. Clive, R. C. Sheppard, Peptide synthesis. Part 1. Preparation and use of polar supports based on poly(dimethylacrylamide). J. Chem. Soc, Perkin 1981, 2, 529-537.
    • (1981) J. Chem. Soc, Perkin , vol.2 , pp. 529-537
    • Arshady, R.1    Aetherton, E.2    Clive, D.L.J.3    Sheppard, R.C.4
  • 64
    • 0001151375 scopus 로고
    • Noinvasive continuous monitoring of solid phase peptide synthesis by acid-base indicator
    • V. Krchnaík, J. Vaígner, P. Safaír, M. Lebl, Noinvasive continuous monitoring of solid phase peptide synthesis by acid-base indicator. Collect. Czech. Chem. Commun. 1988, 53, 2524-2548.
    • (1988) Collect. Czech. Chem. Commun. , vol.53 , pp. 2524-2548
    • Krchnaík, V.1    Vaígner, J.2    Safaír, P.3    Lebl, M.4
  • 65
    • 0014772602 scopus 로고
    • Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides
    • E. Kaiser, R. L. Colescott, C. D. Bossinger, P. I. Cook, Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides. Anal. Biochem. 1969,34, 595-598.
    • (1969) Anal. Biochem. , vol.34 , pp. 595-598
    • Kaiser, E.1    Colescott, R.L.2    Bossinger, C.D.3    Cook, P.I.4
  • 66
    • 0025103048 scopus 로고
    • A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis
    • D. S. King, C. G. Fields, G. B. Fields, A cleavage method which minimizes side reactions following Fmoc solid phase peptide synthesis. Int. J. Pept. Protein Res. 1990, 36, 255-266.
    • (1990) Int. J. Pept. Protein Res. , vol.36 , pp. 255-266
    • King, D.S.1    Fields, C.G.2    Fields, G.B.3
  • 67
    • 0002484110 scopus 로고
    • Streptavidin and avidin recognize peptide ligands with different motifs
    • K. S. Lam, M. Lebl, Streptavidin and avidin recognize peptide ligands with different motifs. Immunomethods 1992, 1, 11-15.
    • (1992) Immunomethods , vol.1 , pp. 11-15
    • Lam, K.S.1    Lebl, M.2
  • 68
    • 0027500111 scopus 로고
    • Multiple release of equimolar amounts of peptides from a polymeric carrier using orthogonal linkage-cleavage chemistry
    • M. Lebl, M. Paítek, P. Kocis, V. Krchnaík, V. J. Hruby, S. E. Salmon, K. S. Lam, Multiple release of equimolar amounts of peptides from a polymeric carrier using orthogonal linkage-cleavage chemistry. Int. J. Pept. Protein Res. 1993, 41, 201-203.
    • (1993) Int. J. Pept. Protein Res. , vol.41 , pp. 201-203
    • Lebl, M.1    Paítek, M.2    Kocis, P.3    Krchnaík, V.4    Hruby, V.J.5    Salmon, S.E.6    Lam, K.S.7
  • 69
    • 0027367140 scopus 로고
    • Symmetrical structure allowing the selective multiple release of a defind quantity of peptide from a single bead of polymeric support
    • P. Kocis, V. Krchnaík, M. Lebl, Symmetrical structure allowing the selective multiple release of a defind quantity of peptide from a single bead of polymeric support. Tetrahedron Lett. 1993, 34, 7251-7252.
    • (1993) Tetrahedron Lett. , vol.34 , pp. 7251-7252
    • Kocis, P.1    Krchnaík, V.2    Lebl, M.3
  • 70
    • 0025119456 scopus 로고
    • Multi-pin peptide synthesis strategy for T cell determination analysis
    • N. J. Maeji, A. M. Bray, H. M. Geysen, Multi-pin peptide synthesis strategy for T cell determination analysis. J. Immunol. Meth. 1990, 134, 23-33.
    • (1990) J. Immunol. Meth. , vol.134 , pp. 23-33
    • Maeji, N.J.1    Bray, A.M.2    Geysen, H.M.3
  • 71
    • 0001689141 scopus 로고
    • Direct cleavage of peptides from a solid support into aqueous buffer. Application in simultaneous multiple peptide synthesis
    • A. M. Bray, J. N. Maeji, R. M. Valerio, R. A. Campbell, M. H. Geysen, Direct cleavage of peptides from a solid support into aqueous buffer. Application in simultaneous multiple peptide synthesis. J. Org. Chem. 1991, 56, 6659-6666.
    • (1991) J. Org. Chem. , vol.56 , pp. 6659-6666
    • Bray, A.M.1    Maeji, J.N.2    Valerio, R.M.3    Campbell, R.A.4    Geysen, M.H.5
  • 72
    • 0026055927 scopus 로고
    • Gas phase cleavage of peptides from a solid support with ammonia vapour. Application in simultaneous multiple peptide synthesis
    • A. M. Bray, J. N. Maeji, A. G. Jhingran, R. M. Valerio, Gas phase cleavage of peptides from a solid support with ammonia vapour. Application in simultaneous multiple peptide synthesis. Tetrahederon Lett. 1991, 32, 6163-6166.
    • (1991) Tetrahederon Lett. , vol.32 , pp. 6163-6166
    • Bray, A.M.1    Maeji, J.N.2    Jhingran, A.G.3    Valerio, R.M.4
  • 74
    • 7044263277 scopus 로고    scopus 로고
    • Synthesis and application of small molecule libraries
    • J. A. Ellman, L. A. Thompson, Synthesis and application of small molecule libraries. Chem. Rev. 1996, 96, 555-600.
    • (1996) Chem. Rev. , vol.96 , pp. 555-600
    • Ellman, J.A.1    Thompson, L.A.2
  • 75
    • 21344450014 scopus 로고    scopus 로고
    • Molecular diversity and libraries of structures: Synthesis and screening
    • Rinnova M., Lebl M. M. Rinnova, M. Lebl, Molecular diversity and libraries of structures: Synthesis and screening. Collect. Czech. Chem. Commun. 1996, 61, 161-222.
    • (1996) Collect. Czech. Chem. Commun. , vol.61 , pp. 161-222
    • Rinnova, M.1    Lebl, M.M.2    Rinnova, M.3
  • 76
    • 0029065615 scopus 로고
    • Combinatorial synthesis: The design of compound libraries and their application to drug discovery
    • N. K. Terrett, M. Gardner, D. W. Gordon, R. J. Kobylecki, J. Steele, Combinatorial synthesis: The design of compound libraries and their application to drug discovery. Tetrahedron 1995, 51, 8135-8173.
    • (1995) Tetrahedron , vol.51 , pp. 8135-8173
    • Terrett, N.K.1    Gardner, M.2    Gordon, D.W.3    Kobylecki, R.J.4    Steele, J.5
  • 77
    • 84958271355 scopus 로고    scopus 로고
    • Compilation of papers in molecular diversity field
    • M. Lebl (1996), Compilation of papers in molecular diversity field, INTERNET World Wide Web address: http://vesta.pd.com.
    • (1996) INTERNET World Wide Web address
    • Lebl, M.1
  • 79
    • 84911274375 scopus 로고
    • Methods for building libraries of peptide structures and determination of consensus structures
    • (Eds.: C. H. Schneider, A. N. Eberle), Proceedings of the 22nd European Peptide Symposium. ESCOM, Leiden
    • M. Lebl, K. S. Lam, P. Kocis, V. Krchnaík, M. Paítek, S. E. Salmon, V. J. Hruby, Methods for building libraries of peptide structures and determination of consensus structures in Peptides 1992 (Eds.: C. H. Schneider, A. N. Eberle), Proceedings of the 22nd European Peptide Symposium. ESCOM, Leiden, 1993, pp. 67-69.
    • (1993) Peptides 1992 , pp. 67-69
    • Lebl, M.1    Lam, K.S.2    Kocis, P.3    Krchnaík, V.4    Paítek, M.5    Salmon, S.E.6    Hruby, V.J.7
  • 80
    • 0027353585 scopus 로고
    • The use of hydrogen-deuterium exchange to facilitate peptide sequencing by electrospray tandem mass spectrometry
    • N. F. Sepetov, O. L. Issakova, M. Lebl, K. Swiderek, D. C. Stahl, T. D. Lee, The use of hydrogen-deuterium exchange to facilitate peptide sequencing by electrospray tandem mass spectrometry. Rapid Commun. Mass Spectrom. 1993, 7, 58-62.
    • (1993) Rapid Commun. Mass Spectrom. , vol.7 , pp. 58-62
    • Sepetov, N.F.1    Issakova, O.L.2    Lebl, M.3    Swiderek, K.4    Stahl, D.C.5    Lee, T.D.6
  • 81
    • 8244235899 scopus 로고
    • Peptide sequencing using mass spectrometry
    • USA Patent 5.470.753
    • N. F. Sepetov, O. L. Issakova, V. Krchnaík, M. Lebl, Peptide sequencing using mass spectrometry. USA Patent 5.470.753 (1995).
    • (1995)
    • Sepetov, N.F.1    Issakova, O.L.2    Krchnaík, V.3    Lebl, M.4
  • 82
    • 0003761016 scopus 로고
    • (Eds.: C. N. McEwen, B. S. Larsen), Marcel Dekker, New York
    • K. Biemann, In Mass Spectrometry of Biological Materials. (Eds.: C. N. McEwen, B. S. Larsen), Marcel Dekker, New York, 1990, pp. 3-(N).
    • (1990) Mass Spectrometry of Biological Materials , pp. 3-(N)
    • Biemann, K.1
  • 83
    • 84958256671 scopus 로고
    • Generation of diverse chemically synthesized peptide libraries
    • (Ed.: N. Yanaihara), Proceedings of the 2nd Japanese Symposium on Peptide Chemistry. ESCOM, Leiden
    • M. H. Geysen, Generation of diverse chemically synthesized peptide libraries in Peptide Chemistry 1992 (Ed.: N. Yanaihara), Proceedings of the 2nd Japanese Symposium on Peptide Chemistry. ESCOM, Leiden, 1993, pp. 3-6.
    • (1993) Peptide Chemistry 1992 , pp. 3-6
    • Geysen, M.H.1
  • 84
    • 0027454521 scopus 로고
    • Identification of substrate-analog trysin inhibitors through the screening of synthetic peptide combinatorial libraries
    • J. Eichler, R. A. Houghten, Identification of substrate-analog trysin inhibitors through the screening of synthetic peptide combinatorial libraries. Biochemistry 1993, 32, 11035-11041.
    • (1993) Biochemistry , vol.32 , pp. 11035-11041
    • Eichler, J.1    Houghten, R.A.2
  • 85
    • 0027199771 scopus 로고
    • Direct selection of antibodies that coordinate metals from semisynthetic combinatorial libraries
    • C. F. Ill Barbas, J. S. Rosenblum, R. A. Lerner, Direct selection of antibodies that coordinate metals from semisynthetic combinatorial libraries. Proc. Natl. Acad. Sci. USA 1993, 90, 6385-6389.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6385-6389
    • Barbas, C.F.1    Rosenblum, J.S.2    Lerner, R.A.3
  • 86
    • 0027450097 scopus 로고
    • The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands
    • C. T. Dooley, R. A. Houghten, The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligands. Life Sci. 1993, 52, 1509-1517.
    • (1993) Life Sci. , vol.52 , pp. 1509-1517
    • Dooley, C.T.1    Houghten, R.A.2
  • 87
    • 0027372945 scopus 로고
    • Acetalins: opioid receptor antagonists determined through the use of synthetic peptide combinatorial libraries
    • C. T. Dooley, N. N. Chung, P. Q. Schiller, R. A. Houghten, Acetalins: opioid receptor antagonists determined through the use of synthetic peptide combinatorial libraries. Proc. Natl. Acad. Sci. USA 1993, 90, 10811-10815.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10811-10815
    • Dooley, C.T.1    Chung, N.N.2    Schiller, P.Q.3    Houghten, R.A.4
  • 88
    • 0027472271 scopus 로고
    • The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors
    • K. S. Lam, V. J. Hruby, M. Lebl, R. J. Knapp, W. M. Kazmierski, E. M. Hersh, S. E. Salmon, The chemical synthesis of large random peptide libraries and their use for the discovery of ligands for macromolecular acceptors. Bioorg. Med. Chem. Lett. 1993, 3, 419-424.
    • (1993) Bioorg. Med. Chem. Lett. , vol.3 , pp. 419-424
    • Lam, K.S.1    Hruby, V.J.2    Lebl, M.3    Knapp, R.J.4    Kazmierski, W.M.5    Hersh, E.M.6    Salmon, S.E.7
  • 89
    • 0028027454 scopus 로고
    • Peptide sequences binding to MHC class I binding peptides
    • M. H. Smith, K. S. Lam, E. M. Hersh, M. Lebl, W. J. Grimes, Peptide sequences binding to MHC class I binding peptides. Mol. Immunol. 1994, 31, 1431-1437.
    • (1994) Mol. Immunol. , vol.31 , pp. 1431-1437
    • Smith, M.H.1    Lam, K.S.2    Hersh, E.M.3    Lebl, M.4    Grimes, W.J.5
  • 90
    • 0028027454 scopus 로고
    • Peptide sequences binding to MHC class I proteins using a synthetic peptide library approach
    • M. H. Smith, K. S. Lam, E. M. Hersh, W. Grimes, Peptide sequences binding to MHC class I proteins using a synthetic peptide library approach. Molecular Immunology 1994, 31, 1431-1437.
    • (1994) Molecular Immunology , vol.31 , pp. 1431-1437
    • Smith, M.H.1    Lam, K.S.2    Hersh, E.M.3    Grimes, W.4
  • 91
    • 0025855156 scopus 로고
    • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
    • K. Falk, O. Rötzschke, S. Stevanovic, G. Jung, H.-G. Rammensee, Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature (London), 1991, 351, 290-296.
    • (1991) Nature (London) , vol.351 , pp. 290-296
    • Falk, K.1    Rötzschke, O.2    Stevanovic, S.3    Jung, G.4    Rammensee, H.-G.5
  • 94
    • 0025158107 scopus 로고
    • Protein kinase recognition sequence motifs
    • B. E. Kemp, R. B. Pearson, Protein kinase recognition sequence motifs. Trends Biochem. Sci. 1990, 15, 342-346.
    • (1990) Trends Biochem. Sci. , vol.15 , pp. 342-346
    • Kemp, B.E.1    Pearson, R.B.2
  • 95
    • 0029046713 scopus 로고
    • Identification and characterization of a novel peptide substrate specific for src-family tyrosine kinase
    • K. S. Lam, J. S. Wu, Q. Lou, Identification and characterization of a novel peptide substrate specific for src-family tyrosine kinase. Intl. J. Protein. Peptide Res. 1995, 45, 587-592.
    • (1995) Intl. J. Protein. Peptide Res. , vol.45 , pp. 587-592
    • Lam, K.S.1    Wu, J.S.2    Lou, Q.3
  • 96
    • 0028327679 scopus 로고
    • Synthetic receptor binding elucidated with an encoded combinatorial library
    • A. Borchardt, C. W. Still, Synthetic receptor binding elucidated with an encoded combinatorial library. J. Am. Chem. Soc. 1994, 116, 373-374.
    • (1994) J. Am. Chem. Soc. , vol.116 , pp. 373-374
    • Borchardt, A.1    Still, C.W.2


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