Penises not required: A systematic review of the potential for human papillomavirus horizontal transmission that is non-sexual or does not include penile penetration

Sexual Health

Volumn 13, Issue 1, 2016, Pages 10-21

  Liu, Zhiyue ^a   Rashid, Tasnuva ^a   Nyitray, Alan G ^a,b  

^a UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^b UNIVERSITY OF TEXAS   (United States)

Author keywords

environment; fomites; hand; nosocomial; penetrative sex; transmission; virgins.

Indexed keywords

VIRUS DNA;

DISEASE TRANSMISSION; FEMALE GENITAL SYSTEM; HETEROSEXUALITY; HORIZONTAL TRANSMISSION; HUMAN; NONHUMAN; PENIS; REVIEW; SEXUAL INTERCOURSE; SEXUAL TRANSMISSION; SYSTEMATIC REVIEW; VERRUCA VULGARIS; VIRGINITY; WART VIRUS; CROSS INFECTION; FEMALE; GENETICS; MALE; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTION; PATHOGENICITY; PREVALENCE; SEXUAL BEHAVIOR; TRANSMISSION; VIROLOGY;

CROSS INFECTION; DISEASE TRANSMISSION, INFECTIOUS; DNA, VIRAL; FEMALE; GENITALIA, FEMALE; HETEROSEXUALITY; HUMANS; MALE; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; PREVALENCE; SEXUAL BEHAVIOR;

EID: 84958239718     PISSN: 14485028     EISSN: 14498987     Source Type: Journal    
DOI: 10.1071/SH15089     Document Type: Review

References (62)

1. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans Biological agents. Volume 100 B. A review of human carcinogens: human papillomaviruses. IARC Monog Eval Carc 2012; 100(Pt B): 255-313
2. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans. Human papillomaviruses. IARC Monog Eval Carc 2007; 90: 136-65
3. Doorbar J, Quint W, Banks L, Bravo IG, Stoler M, Broker TR, et al. The biology and life-cycle of human papillomaviruses. Vaccine 2012; 30(Suppl 5): F55-70. doi:10.1016/j.vaccine.2012.06.083
4. Martin-Hernan F, Sanchez-Hernandez JG, Cano J, Campo J, del Romero J. Oral cancer, HPV infection and evidence of sexual transmission. Med Oral Patol Oral 2013; 18: e439-44. doi:10.4317/ medoral.18419
5. Freitas AC, Mariz FC, Silva MA, Jesus AL. Human papillomavirus vertical transmission: review of current data. Clin Infect Dis 2013; 56: 1451-6. doi:10.1093/cid/cit066
6. VonVille HM. Systematic review workbook for tracking search strategies & results and screening titles & abstracts. 2014. Available online at: http://libguides.sph.uth.tmc.edu/excel-SR-workbook [verified March 2014]
7. Beznos G, Coates V, Focchi J, Omar HA. Biomolecular study of the correlation between papillomatosis of the vulvar vestibule in adolescents and human papillomavirus. ScientificWorldJournal 2006; 6: 628-36. doi:10.1100/tsw.2006.130
8. Bumbuliene Z, Alisauskas J, Sepetiene A. High-risk HPV infection in sexually active and non active young women. Cent Eur J Med 2011; 6: 456-62
9. Doerfler D, Bernhaus A, Kottmel A, Sam C, Koelle D, Joura EA. Human papilloma virus infection prior to coitarche. Am J Obstet Gynecol 2009; 200: 487.e1-5. doi:10.1016/j.ajog.2008.12.028
10. Fairley CK, Chen S, Tabrizi SN, Leeton K, Quinn MA, Garland SM. The absence of genital human papillomavirus DNA in virginal women. Int J STD AIDS 1992; 3: 414-7
11. Ji J, Sun HK, Smith JS, Wang H, Esser MT, Hu S, et al. Seroprevalence of human papillomavirus types 6, 11, 16 and 18 in Chinese women. BMC Infect Dis 2012; 12: 137-46. doi:10.1186/ 1471-2334-12-137
12. Marrazzo JM, Koutsky LA, Kiviat NB, Kuypers JM, Stine K. Papanicolaou test screening and prevalence of genital human papillomavirus among women who have sex with women. Am J Public Health 2001; 91: 947-52. doi:10.2105/AJPH.91.6.947
13. Oh JK, Ju YH, Franceschi S, Quint W, Shin HR. Acquisition of new infection and clearance of type-specific human papillomavirus infections in female students in Busan, South Korea: A follow-up study. BMC Infect Dis 2008; 8: 1-6. doi:10.1186/1471-2334-8-13
14. Pao CC, Tsai PL, Chang YL, Hsieh TT, Jin JY. Possible non-sexual transmission of genital human papillomavirus infections in young women. Eur J Clin Microbiol 1993; 12: 221-3. doi:10.1007/ BF01967118
15. Peters AA, Trimbos JB. The absence of human papilloma virus (HPV) related parameters in sexually non-active women. Eur J Gynaecol Oncol 1994; 15: 43-5
16. Rylander E, Ruusuvaara L, Almstromer MW, Evander M, Wadell G. The absence of vaginal human papillomavirus 16 DNA in women who have not experienced sexual intercourse. Obstet Gynecol 1994; 83: 735-7
17. Shew ML, Weaver B, Tu W, Tong Y, Fortenberry JD, Brown DR. High frequency of human papillomavirus detection in the vagina before first vaginal intercourse among females enrolled in a longitudinal cohort study. J Infect Dis 2013; 207: 1012-5. doi:10.1093/infdis/jis775
18. Tay SK, Oon LL. Prevalence of cervical human papillomavirus infection in healthy women is related to sexual behaviours and educational level: A cross-sectional study. Int J STD AIDS 2014; 25: 1013-21
19. Shimada T, Miyashita M, Miura S, Nakayama D, Miura K, Fukuda M, et al. Genital human papilloma virus infection in mentallyinstitutionalized virgins. Gynecol Oncol 2007; 106: 488-9. doi:10.1016/j.ygyno.2007.04.018
20. Shin HR, Lee DH, Herrero R, Smith JS, Vaccarella S, Hong SH, et al. Prevalence of human papillomavirus infection in women in Busan, South Korea. Int J Cancer 2003; 103: 413-21. doi:10.1002/ ijc.10825
21. Tay SK, Ho TH, Lim-Tan SK. Is genital human papillomavirus infection always sexually transmitted? Aust N Z J Obstet Gynaecol 1990; 30: 240-2. doi:10.1111/j.1479-828X.1990.tb03223.x
22. Widdice LE, Brown DR, Bernstein DI, Ding L, Patel D, Shew M, et al. Prevalence of human papillomavirus infection in young women receiving the first quadrivalent vaccine dose. Arch Pediatr Adolesc Med 2012; 166: 774-6. doi:10.1001/archpediatrics.2012.586
23. Winer RL, Hughes JP, Feng Q, Xi LF, Cherne S, O'Reilly S, et al. Detection of genital HPV types in fingertip samples from newly sexually active female university students. Cancer Epidem Biomar 2010; 19: 1682-5. doi:10.1158/1055-9965.EPI-10-0226
24. Winer RL, Lee SK, Hughes JP, Adam DE, Kiviat NB, Koutsky LA. Genital human papillomavirus infection: incidence and risk factors in a cohort of female university students. Am J Epidemiol 2003; 157: 218-26. doi:10.1093/aje/kwf180
25. Thilagavathi A, Shanmughapriya S, Vinodhini K, Das BC, Natarajaseenivasan K. Prevalence of human papillomavirus (HPV) among college going girls using self collected urine samples from Tiruchirappalli, Tamilnadu. Arch Gynecol Obstet 2012; 286: 1483-6. doi:10.1007/s00404-012-2500-6
26. Frega A, Cenci M, Stentella P, Cipriano L, De Ioris A, Alderisio M, et al. Human papillomavirus in virgins and behaviour at risk. Cancer Lett 2003; 194: 21-4. doi:10.1016/S0304-3835(03)00048-X
27. Partridge JM, Hughes JP, Feng Q, Winer RL, Weaver BA, Xi LF, et al. Genital human papillomavirus infection in men: incidence and risk factors in a cohort of university students. J Infect Dis 2007; 196: 1128-36. doi:10.1086/521192
28. Widdice LE, Breland DJ, Jonte J, Farhat S, Ma Y, Leonard AC, et al. Human papillomavirus concordance in heterosexual couples. J Adolesc Health 2010; 47: 151-9. doi:10.1016/j.jadohealth.2010. 01.006
29. Widdice L, Ma Y, Jonte J, Farhat S, Breland D, Shiboski S, et al. Concordance and transmission of human papillomavirus within heterosexual couples observed over short intervals. J Infect Dis 2013; 207: 1286-94. doi:10.1093/infdis/jit018
30. Hernandez BY, Wilkens LR, Zhu X, Thompson P, McDuffie K, Shvetsov YB, et al. Transmission of human papillomavirus in heterosexual couples. Emerg Infect Dis 2008; 14: 888-94. doi:10.3201/eid1406.0706162
31. Sonnex C, Strauss S, Gray JJ. Detection of human papillomavirus DNA on the fingers of patients with genital warts. Sex Transm Infect 1999; 75: 317-9. doi:10.1136/sti.75.5.317
32. Forslund O, Nordin P, Hansson BG. Mucosal human papillomavirus types in squamous cell carcinomas of the uterine cervix and subsequently on fingers. Br J Dermatol 2000; 142: 1148-53. doi:10.1046/j.1365-2133.2000.03540.x
33. Hunt R, Hwa C, Tzu J, Patel R, Tyring SK, Stein J. Multiple human papillomavirus-16 associated digital squamous-cell carcinomas in an immunocompetent woman with prior human papillomavirus-related genital carcinoma. Dermatol Online J 2011; 17: 20
34. Hernandez BY, Shvetsov YB, Goodman MT, Wilkens LR, Thompson PJ, Zhu X, et al. Genital and extra-genital warts increase the risk of asymptomatic genital human papillomavirus infection in men. Sex Transm Infect 2011; 87: 391-5. doi:10.1136/sti.2010.048876
35. Jin F, Prestage GP, Kippax SC, Pell CM, Donovan B, Templeton DJ, et al. Risk factors for genital and anal warts in a prospective cohort of HIV-negative homosexual men: The HIM study. Sex Transm Dis 2007; 34: 488-93
36. Handley J, Dinsmore W, Maw R, Corbett R, Burrows D, Bharucha H, et al. Anogenital warts in prepubertal children; sexual abuse or not? Int J STD AIDS 1993; 4: 271-9
37. Rock B, Naghashfar Z, Barnett N, Buscema J, Woodruff JD, Shah K. Genital tract papillomavirus infection in children. Arch Dermatol 1986; 122: 1129-32. doi:10.1001/archderm.1986.01660220047012
38. Fleming KA, Venning V, Evans M. DNA typing of genital warts and diagnosis of sexual abuse of children. Lancet 1987; 330: 454. doi:10.1016/S0140-6736(87)90987-1
39. Klinglmair G, Pichler R, Zelger B, Dogan HS, Becker T, Esterbauer J, et al. Prevalence of the human papillomavirus (HPV) expression of the inner prepuce in asymptomatic boys and men. World J Urol 2013; 31: 1389-94. doi:10.1007/s00345-012-0997-8
40. Myhre AK, Dalen A, Berntzen K, Bratlid D. Anogenital human papillomavirus in non-abused preschool children. Acta Paediatr 2003; 92: 1445-52. doi:10.1111/j.1651-2227.2003.tb00830.x
41. McCance DJ, Campion MJ, Baram A, Singer A. Risk of transmission of human papillomavirus by vaginal specula. Lancet 1986; 328: 816-7. doi:10.1016/S0140-6736(86)90343-0
42. Kac G, Podglajen I, Si-Mohamed A, Rodi A, Grataloup C, Meyer G. Evaluation of ultraviolet C for disinfection of endocavitary ultrasound transducers persistently contaminated despite probe covers. Infect Control Hosp Epidemiol 2010; 31: 165-70. doi:10.1086/649794
43. Casalegno JS, Le Bail Carval K, Eibach D, Valdeyron ML, Lamblin G, Jacquemoud H, et al. High risk HPV contamination of endocavity vaginal ultrasound probes: An underestimated route of nosocomial infection? PLoS One 2012; 7: 1-4. doi:10.1371/journal.pone.0048137
44. Ma STC, Yeung AC, Chan PKS, Graham CA. Transvaginal ultrasound probe contamination by the human papillomavirus in the emergency department. Emerg Med J 2013; 30: 472-5. doi:10.1136/emermed-2012-201407
45. Ferenczy A, Bergeron C, Richart RM. Human papillomavirus DNA in fomites on objects used for the management of patients with genital human papillomavirus infections. Obstet Gynecol 1989; 74: 950-4
46. Ilmarinen T, Auvinen E, Hiltunen-Back E, Ranki A, Aaltonen L, Pitkaranta A. Transmission of human papillomavirus DNA from patient to surgical masks, gloves and oral mucosa of medical personnel during treatment of laryngeal papillomas and genital warts. Eur Arch Otorhinolaryngol 2012; 269: 2367-71. doi:10.1007/ s00405-012-2049-9
47. Kashima HK, Kessis T, Mounts P, Shah K. Polymerase chain reaction identification of human papillomavirus DNA in CO2 laser plume from recurrent respiratory papillomatosis. Otolaryng Head Neck 1991; 104: 191-5
48. Hallmo P, Naess O. Laryngeal papillomatosis with human papillomavirus DNA contracted by a laser surgeon. Eur Arch Otorhinolaryngol 1991; 248: 425-7. doi:10.1007/BF01463570
49. Garden JM, O'Banion MK, Shelnitz LS, Pinski KS, Bakus AD, Reichmann ME, et al. Papillomavirus in the vapor of carbon dioxide laser-treated verrucae. JAMA 1988; 259: 1199-202. doi:10.1001/jama.1988.03720080033024
50. Bergbrant I, Samuelsson L, Olofsson S, Jonassen F,, Ricksten A. Polymerase chain reaction for monitoring human papillomavirus contamination of medical personnel during treatment of genital warts with CO2 laser and electrocoagulation. Acta Derm Venereol 1994; 74: 393-5
51. Andre P, Orth G, Evenou P, Guillaume JC, Avril MF. Risk of papillomavirus infection in carbon dioxide laser treatment of genital lesions. J Am Acad Dermatol 1990; 22: 131-2. doi:10.1016/S0190-9622(08)80016-3
52. Lobraico RV, Schifano MJ, Brader KR. Acquired HPV lesions compared in laser and nonlaser users. J Gynecol Surg 1989; 5: 77-85. doi:10.1089/gyn.1989.5.77
53. Hughes PSH, Hughes AP. Absence of human papillomavirus DNA in the plume of erbium: YAG laser-treated warts. J Am Acad Dermatol 1998; 38: 426-8. doi:10.1016/S0190-9622(98)70500-6
54. Strauss S, Sastry P, Sonnex C, Edwards S, Gray J. Contamination of environmental surfaces by genital human papillomaviruses. Sex Transm Infect 2002; 78: 135-8. doi:10.1136/sti.78.2.135
55. Strauss S, Stephen H, Sonnex C, Gray J. Contamination of environmental surfaces by genital human papillomaviruses (HPV): A follow up study. Sex Transm Infect 2003; 79: 426-7. doi:10.1136/ sti.79.5.426-a
56. Smelov V, Eklund C, Arroyo Muhr LS, Hultin E, Dillner J. Are human papillomavirus DNA prevalences providing high-flying estimates of infection? An international survey of HPV detection on environmental surfaces. Sex Transm Infect 2013; 89: 627. doi:10.1136/sextrans-2013-051280
57. Anderson TA, Schick V, Herbenick D, Dodge B, Fortenberry JD. A study of human papillomavirus on vaginally inserted sex toys, before and after cleaning, among women who have sex with women and men. Sex Transm Infect 2014; 90: 529-31. doi:10.1136/sextrans-2014-051558
58. Winer RL, Hughes JP, Feng Q, Xi LF, Cherne S, O'Reilly S, Kiviat NB, Koutsky LA. Early natural history of incident, type-specific human papillomavirus infections in newly sexually active young women. Cancer Epidemiol Biomarkers Prev 2011; 20: 699-707. doi:10.1158/1055-9965.EPI-10-1108
59. Coutlee F, Hankins C, Lapointe N. Comparison between vaginal tampon and cervicovaginal lavage specimen collection for detection of human papillomavirus DNA by the polymerase chain reaction. The Canadian Women's HIV Study Group. J Med Virol 1997; 51: 42-7. doi:10.1002/(SICI)1096-9071(199701)51:1<42::AID-JMV7> 3.0.CO;2-S
60. Roden RB, Lowy DR, Schiller JT. Papillomavirus is resistant to desiccation. J Infect Dis 1997; 176: 1076-9. doi:10.1086/516515
61. Ding DC, Chang YC, Liu HW, Chu TY. Long-term persistence of human papillomavirus in environments. Gynecol Oncol 2011; 121: 148-51. doi:10.1016/j.ygyno.2010.11.040
62. Nyitray AG, Lin HY, Fulp WJ, Chang M, Menezes L, Lu B, et al. The role of monogamy and duration of heterosexual relationships in human papillomavirus transmission. J Infect Dis 2014; 209: 1007-15. doi:10.1093/infdis/jit615