PEG grafted polystyrene tentacle polymers: Physico-chemical properties and application in chemical synthesis

Combinatorial Peptide and Nonpeptide Libraries: A Handbook

Volumn , Issue , 2007, Pages 425-464

  Rapp, Wolfgang ^a  

^a Rapp Polymere GmbH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

POLYETHYLENE OXIDES;

GRAFTED POLYSTYRENE; PHYSICOCHEMICAL PROPERTY;

POLYETHYLENE GLYCOLS;

EID: 84958232329     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9783527614912.ch16     Document Type: Chapter

References (165)

1. R. B. Merrifield, Fed. Proc, Fed. Am. Soc. Exp. Biol. 1962, 21, 412.
2. R. B. Merrifield, I Am. Chem. Soc. 1963, 85, 2149.
3. G. R. Marshall, R. B. Merrifield in Biochemical Aspects of Reactions on Solid Supports, Academic Press, NY; 1971.
4. G. Baray, R. B. Merrifield, The Peptides, Academic Press, NY; 1980, 2.
5. R. L. Letsinger, J. L. Finnan, G. A. Heavner, W. B. Lunsford, J. Am. Chem. Soc. 1975, 97, 3278.
6. E. Uhlmann, A. Peyman, Chem. Rev. 1990, 90, 543.
7. J. W. Engels, E. Uhlmann, Angew. Chem. 1989,101, 733;
8. Angew. Chem. Int. Ed. Engl. 1989, 28, 716.
9. R. H. Grubbs, L. C. Kroll, J. Am. Chem. Soc. 1971, 93, 3062.
10. C. U. Pittmann Jr., L. R. Smith, J. Am. Chem. Soc. 1975, 97, 1749.
11. C. U. Pittmann Jr., L. R. Smith, R. M. Hanes, J. Am. Chem Soc. 1975, 97, 742.
12. R. H. Grubbs, Chem. Technol. 1977, 512.
13. Y. Chaurin, D. Commerenc, E Dawens, Prog. Polym. Sci. 1977, 5, 95.
14. V. A. Kubanov, V. J. Smetanyuk, Makromol. Chem. Phys., Suppl 1981, 5, 121.
15. G. Manecke, W. Storck, Angew. Chem. 1978, 90, 691;
16. Angew. Chem. Int. Ed. Engl. 1978, 17, 657.
17. ] C. U. Pittmann Jr., Comprehensive Organometallic Chemistry (Ed.: G. Wilkinson), Pergamon Press, Oxford, New York, Toronto, Sydney, Paris, Frankfurt, 1982, Vol. 8, p. 553 ff.
18. M. Kaneko, E. Tsuchida, Macromol. Rev. 1981, 16, 397.
19. H. D. Orth, W. Brummer, Angew. Chem. 1972, 84, 319;
20. Angew. Chem. Int. Ed. Engl. 1972, 11, 249.
21. H. H. Weetall, Chem. Ztg. 1973, 97, 611.
22. G. Manecke, Chimia 1974, 28, 467.
23. J. Chibata in Immobilized Enzymes, Wiley, New York, 1978, pp. 9-142 and references therein.
24. G. Manecke, E. Ehrenthal, J. Schlünsen, Characterization of Immobilized Biocatalysts (Ed.: K. Buchholz) Schön u. Wetzel GmbH, Frankfurt, 1979, pp. 49-109 and references therein.
25. B. P. Scharma, L. F. Baily, R. A. Messing, Angew. Chem. 1982, 94, 836
26. Angew. Chem. Int. Ed Engl. 1982, 21, 837.
27. L. Goldstein, G. Manecke, Applied Biochemistry and Bioengineering (Eds.: L. S. Wingard Jr., E. Katchalski-Kutzir, L. Goldstein), Academic Press, New York, San Francisco, London, 1976, Vol. 1, pp. 23-110 and references therein.
28. John F. Kennedy in Solid Phase Biochemistry, Analytical and Synthetic Aspects (Ed.: William H. Scouten), John Wiley & Sons, New York, Chichester, Brisbane, Toronto, Singapore, 1983, pp. 257-361 and references therein.
29. K. Poralla, Biotechnology Vortrag Hauptversammlung MNU, 74th 1983, 21 ff.
30. A. Rosevear, J Chem. Technol. Biotechnol, Biotechnol. 1984, 34B(3), 127.
31. A. S. Attiyat, G. D. Christian, Am. Biotechnol. Lab., 2(2) 1984, 8,10, 12-16.
32. T. M. Fyles, C. C. Lenzoff, Can. J. Chem. 1975, 54, 935.
33. G. A. Crosby, N. M. Weinshenker, H. S. Uh, J. Am. Chem. Soc. 1974, 97, 2232.
34. N. M. Weinshenker, C. M. Shen, Tetrahedron Lett. 1972, 3381.
35. W. H. Daly, Makromol. Chem., Suppl. 1979, 180, 3.
36. C. G. Overberger, K. N. Sannes, Angew. Chem. 1974, 86, 139;
37. Angew. Chem. Int. Ed. Engl. 1974, 13, 99.
38. A. Akelah, D. C. Sherrington, Polymer 1983, 24, 1369.
39. E. Atherton, R. C. Sheppard, Peptides 1974 (Ed.: Y. Wolman), Halsted Press, NY, 1975, pp. 123-127.
40. F. G. W. Butwell, E. J. Haws, R. Epton, Macromol. Chem. Macromol. Symp. 1986,19, 69-77.
41. E. Atherton, E. Brown, R. C. Sheppard, J. Chem. Soc, Chem. Commun. 1981, 1151-1152.
42. P. W. Small, D. C. Sherrington, J. Chem. Soc, Chem. Commun. 1989, 1589-1591.
43. E. Bayer, B. Hemmasi, K. Albert, W. Rapp, M. Dengler, Peptides: Structure and Function (Ed.: V. J. Hruby, D. H. Rich), Pierce Chemical Company, 1983, pp. 87-89.
44. E. Bayer, W. Rapp, Chemistry of Peptides and Proteins (Eds.: W. Voelter, E. Bayer, Yu. A. Ovchinnikov, V. T. Ivanov) Walter de Gruyter & Co., Berlin, New York, 1986, Vol. 3, pp. 3-8.
45. E. Bayer, W. Rapp, Dtsch. Offen. DE 3 500 180,10. Juli 1986, Anm. 4. Jan 1985, C. A. 106, 50859.
46. E. Bayer, Angew. Chem. 1991, 103, 117;
47. Angew. Chem. Int. Ed. Engl. 1991, 30, 113.
48. E. Bayer, W. Rapp, Poty(Ethytene Glycol) Chemistry: Biotechnical and Biomedical Applications (Ed.: M. Harris) Plenum Press, New York, 1992, pp. 325-345.
49. TentaGel, registered trademark of Fa. Rapp Polymere GmbH, Tuübingen.
50. E. Bayer, Nachr. Chem. Techn. 1972, 20, 495.
51. M. Mutter, H. Hagenmaier, E. Bayer, Angew. Chem. 1971, 83, 883;
52. Angew. Chem. Int. Ed Engl 1971, 10, 811.
53. E. Bayer, M. Mutter, Nature (London) 1971, 237, 512.
54. M. Mutter, E. Bayer, The Peptides (Eds.: E. Gross, J. Meienhofer) Academic Press, New York, 1970, Vol. 2, 285.
55. M. Mutter, R. Uhmann, E. Bayer, Liebigs Ann. Chem. 1975, 901.
56. E. Bayer, M. Mutter, R. Uhmann, J. Polster, H. Mauser, J. Am. Chem. Soc 1974, 96, 7333.
57. M. Mutter, E. Bayer, Angew. Chem. 1974, 86, 163;
58. Angew. Chem. Int. Ed. Engl. 1974, 13, 149.
59. A. Warshavsky, R. Kaliv, A. Doshe, H. Berkovitz, A. Patchornik, J. Am. Chem. Soc 1979, 101, 4249.
60. E. Tsuchida, H. Nishide, N. Shimidazu, A. Yamada, M. Keneko, Makromol. Chem. Rapid Commun. 1981, 2, 621.
61. S. Zalipsky, M. Albericio G. Barany, Peptides, Chemistry and Biology (Eds.: C. Deber, V. J. Hruby, K. D. Kopple), Proceedings of the Ninth American Peptide Symposium, Rirce Chemical Company, Rockford, II, 1985, pp. 257-260.
62. E. Bayer, B. Hemmasi, K. Albert, W. Rapp, M. Dengler, Peptides: Structure and Function, (Eds.: V. J. Hruby, D. H. Rich) Pierce Chem. Comp. 1983, p. 87.
63. E. Bayer, W. Rapp, German Pat. DOS 3 714 258, 1988.
64. E. Bayer, M. Dengler, B. Hemmasi, Int. J. Pept. Protein Res. 1985, 25, 178.
65. E. Bayer, W. Rapp, W. Voelter, E. Bayer, Chemistry of Peptides and Proteins (Eds.: Y. A. Ovchinnikov, V. I. Ivanov), Walter de Gruyter, Berlin, 1986, p. 3.
66. E. Bayer, H. Hellstern, H. Eckstein, Z. Naturforsch. 1987, 42c, 455.
67. W. Rapp, L. Zhang, R. Häbich, E. Bayer, Peptides 1988, Proceedings of the 20th European Peptide Symposium (Eds.: G. Jung, E. Bayer), Walter de Gruyter, Berlin, 1989, 1989.
68. W. Rapp, Thesis 1985.
69. E. Bayer, K. Albert, H. Willisch, W. Rapp, B. Hemmasi, Macromolecules 1990,23, 1937.
70. G. C. Look, C. P. Holmes, J. P. Chinn, M. A. Gallap, J. Org. Chem. 1994,59, 7588-7590.
71. W. L. Fitch, G. Detre, C. P. Holmes, J. Org. Chem. 1994, 59, 7955-7956.
72. J. Rudinger, P. Buetzer, Peptides 1974 (Ed.: J. Wolman), Wiley, New York, 1975, p. 211.
73. E. Bayer, W. Rapp, Poly(Ethyleneglycol) Chemistry: Biotechnical and Biomedical Application (Ed.: M. Harris) Plenum Press, New York, 1992, pp. 325-344.
74. T. Hori, W. Rapp, E. Bayer, Proceedings of the 30th Symposium on Chemistry of Dying, Osaka, Japan, 1988, p. 42.
75. T. Hori, W. Rapp, E. Bayer, unpublished results.
76. FurkaFurka, et al, 10th Int. Symp. Med. Chem. Budapest, 1988
77. Furka, et al., Int. J. Pept. Protein Res., 1991, 37, 487.
78. Furka, et al., 14th Int. Cong, of Biochem. Prague, 1988.
79. S. E. Salmon, E. M. Hersh, V. J. Hruby, W. M. Kazncierski, R. J. Knapp, Nature (London) 1991, 354, 82-84.
80. W. Rapp, V. Gnau, unpublished results.
81. W. Rapp, unpublished results.
82. L. Zhang, W. Rapp, E. Bayer, Peptides 1990, Proceedings of the 21st European Peptide Symposium (Eds.: E. Giralt, D. Andreus) Escom, Leiden, 1991, pp. 196-197.
83. W. Rapp in Peptides 1992, Proceedings of the 22nd European Peptide Symposium (Eds.:C. H. Schneider, A. N. Eberle) Escom, Leiden, 1993, p. 243.
84. L. Otvos Jr., I. Elekes, V. M. Y. Lee, Int. J. Pept. Protein Res. 1989, 34, 129.
85. H. B. A. De Bont, J. H. van Boom, R. M. J. Liskamp, Tetrahedron Lett. 1990, 31, 2495.
86. W. Rapp, L. Zhang, W. Bannwarth, E. Bayer, Peptides 1992, Proceedings of the 22nd European Peptide Symposium, Escom, Leiden, 1993, pp. 347-348.
87. L. Zhang, W. Rapp, E. Bayer, Peptides 1992, Proceedings of the 22nd European Peptide Symposium, (Eds.: C. H. Schneider, A. N. Eberle) Escom, Leiden, 1993, pp. 432-433.
88. L. Zhang, W. Rapp, E. Bayer, Peptides 1992, Proceedings of the 22nd European Peptide Symposium, (Eds.: C. H. Schneider, A. N. Eberle) Escom, Leiden, 1993, pp. 432-433.
89. W. Rapp, E. Bayer, Innovations and Perspectives in Solid Phase Synthesis, Peptides, Polypeptides and Oligonucleotides, (Ed.: R. Epton) Intercept Ltd., Andover, 1992, p. 259.
90. W. Rapp, H. Fritz, E. Bayer, Peptides, Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium, (Eds.: J. A. Smith, J. E. Rivier) Escom, Leiden, 1992, p. 529.
91. E. Bayer, C. Goldammer, Peptides, Chemistry and Biology, Proceedings of the Twelfth American Peptide Symposium, (Eds.: J. A. Smith, J. E. Rivier) Escom, Leiden, 1992, p. 589.
92. W. Rapp, E. Bayer, Peptides 1992, Proceedings of the 22nd European Peptide Symposium, (Eds.: C. H. Schneider, A. N. Eberle) Escom, Leiden, 1993, p. 25.
93. W. Rapp, E. Bayer, Peptide Chemistry 1992, Proceedings of the 2nd Japanese Symposium on Peptide Chemistry, (Ed.: N. Yanaihara) Escom, Leiden, 1993, p. 7.
94. W. Rapp, E. Bayer, Peptides, Chemistry and Biology, Proceedings of the Thirteenth American Peptide Symposium, (Eds.: J. A. Smith, R. S. Hodges) Escom, Leiden, 1994, p. 40.
95. R. Lotz, L. Zhang, A. Korn, F. Zühl, G. Boheim, E. Bayer, G. Jung, J. Pept. Sci. 1996, submitted.
96. S. Modrow, B. Hoflacher, R. Merz, H. Wolf, J. Immunol. Methods 1989, 118, 1.
97. P. M. Fischer, A. Comis, M. E. Howden, J. Immunol. Methodsi 1989, 118, 119-123.
98. M. Flegel, D. Pichova, P. Minarik, R. C. Sheppard in Peptides 1990, Proceedings of the 21st European Peptide Symposium, (Eds.: E. Giralt, D. Andreu) Escom, Leiden, 1991, pp. 837-838.
99. P. Kanda, R. C. Kennedy, J. T. Sparrow, Int. J. Pept. Protein Res. 1991, 38, 385-391.
100. R. C. Kennedy, G. R. Dreesman, T. C. Chanh, R. N. Boswell, J. S. Allan, T. H. Lee,
101. M. Zeppezauer, R. Hoffmann, A. Schönberger, S. Rawer, W. Rapp, E. Bayer, Z. Naturforsch. 1993, 48b, 1801-1806.
102. W. Rapp, L. Zhang, A. G. Beck-Sickinger, K. Deres, K.-H. Wiesmüller, G. Jung, E. Bayer, Peptides 1990, Proceedings of the 21st European Peptide Symposium, (Eds.:E. Giralt, D. Andreu), Escom, Leiden, 1991, p. 849.
103. S. Butz, S. Rawer, W. Rapp, U. Birsner, Pept. Res. 1994, 7, 20-23.
104. K.-H. Wiesmüller, G. Jung, G. Hess, Vaccine 1989, 7, 29.
105. B. Kleine, W. Rapp, K.-H. Wiesmüller, M. Edinger, W. Beck, J. Metzger, R. Ataullakha-nov, G. Jung, W. G. Bessler, Immunobiol. 1994, 110, 53-66.
106. W. Rapp, L. Zhang, C. Muller, F. Zuhl, K.-H. Wiesmüller, G. Jung, E. Bayer, Innovations and Perspectives in Solid Phase Synthesis, Peptides, Proteins and Nucleic Acids, Proceedings of the 3rd International Symposium 1993, (Ed.: R. Epton), Mayflower Worldwide Limited, Birmingham, 1994, p. 197.
107. R. L. Letsinger, V. Mahalevan, J. Am. Chem. Soc. 1966, 87, 3526.
108. H. Ito, Y. Ike, S. Ikuta, K. Itakura, Nucl. Acids Res. 1982, 10, 1755-1769.
109. T. Tanaka, T. Sakata, K. Fujimoto, M. Ikehara, Nucl. Acids Res. 1987,15, 6209-6224.
110. F. Bardella, E. Giralt, E. Pedroso, Tetrahedron Lett. 1990, 31, 6231-6234.
111. E. Bayer, K. Bleicher, M. Maier, H. J. Gaus, K. Schmeer, T. Bauer, Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications: Collected Papers, Third International Symposium, 1993, Oxford, UK, (Ed.: R. Epton) Mayflower Worldwide Limited, Birmingham, 1994, pp. 9-20.
112. R. T. Pon, N. Usman, K. K. Ogilvie, Biotechniques 1988, 6, 768-775.
113. M. D. Matteucci, M. H. Caruthers, J. Am. Chem. Soc. 1981, 103, 3185-3191.
114. G. R. Gough, M. J. Brunden, P. T. Gilham, Tetrahedron Lett. 1981, 22, 4177-4180.
115. S. P. Adams, K. S. Kavka, E. J. Wykes, S. B. Holder, G. R. Galluppi, J. Am. Chem. Soc. 1983, 105, 661-663.
116. S. Frey, N. D. Sinha, Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications, Collected Papers, Third International Symposium, 1993, Oxford, UK, (Ed.: R. Epton) Mayflower Worldwide Limited, Birmingham 1994, pp. 9-20.
117. G. Grubler, H. Straubinger, W. Reinig, H. Echner, M. Geiger, W. Voelter in Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications, Collected Papers, Third International Symposium, 1993, Oxford, UK, (Ed.: R. Epton) Mayflower Worldwide Limited, Birmingham, 1994, pp. 9-20.
118. H. Gao, B. L. Gaffney, R. A. Jones, Tetrahedron Lett. 1991, 32, 5477-5480.
119. P. Wright, D. Lloyd, W. Rapp, A. Andrus, Tetrahedron Lett. 1993, 34, 3373-3376.
120. E. Bayer, Angew. Chem. 1991, 103, 117;
121. Angew. Chem. Int. Ed. Engl. 1991, 30, 113.
122. C. Bleicher, Thesis, University of Tubingen, 1995.
123. E. Bayer, K. Bleicher, M. Maier, Z. Naturforsch. 1995, 50b, 1096-1100.
124. J. Weiler, T. Maier, W. Pfleiderer, Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications, Collected Papers, Third International Symposium, 1993, Oxford, UK, (Ed.: R. Epton) Mayflower Worldwide Limited, Birmingham, 1994, pp. 9-20.
125. D. Tsou, P. Wright, D. Lloyd, A. Andreus, Solid Phase Synthesis of Peptides, Proteins, Nucleic Acids, Biological and Biomedical Applications, Collected Papers, Third International Symposium, 1993, Oxford, UK, (Ed.: R. Epton) Mayflower Worldwide Limited, Birmingham, 1994, pp. 9-20.
126. A. Andrus, presented at the 4th International Symposium on Solid Phase Synthesis, Edinburgh, 1995.
127. M. Lebl, V. Krchftak, N. F. Sepetov, B. Seligmann, S. Felder, Biopolymers (Peptide Science), (Ed.: J. Wiley & Sons), 1995, 177-198.
128. S. E. Salmon, K. S. Lam, M. Lebl, A. Kandola, P. S. Khattri, S. Wade, M. Patek, P. Kocis, V. Krchftak, D. Thorpe, S. Felder, Proc. Natl. Acad. Sci. USA (Chemistry)
129. M. Lebl, V. Krchftak, S. E. Salmon, K. S. Lam, Methods: A Companion to Methods in Enzymology 1994, 6, 381-387.
130. K. S. Lam, Z. Zhao, S. Wade, V. Krchftak, M. Lebl, Drug Development Research 1994, 33, 157-160.
131. V. Nikolaiev, A. Stierandova, V. Krchftak, B. Seligmann, K. S. Lam, S. E. Salmon, M. Lebl, Peptide Res. 1993, 6, 161-170.
132. M. Lebl, M. Patek, P. Kocis, V. Krchftak, V. Hruby, S. E. Salmon, K. S. Urn, Int. J. Pept. Protein Res. 1993, 41, 201-203.
133. J. Vagner, V. Krchftak, N. F. Sepetov, P. Strop, K. S. Lam, G. Barany, M. Lebl, Innovation and Perspectives in Solid Phase Synthesis and Related Technologies, Collected Papers, Third Int. Symp. Oxford, England, (Ed.: R. Epton) 1993, p. 347.
134. M. Lebl, V. Krchftak, N. F. Sepetov, V. Nikolaiev, A. Stierandova, P. Safar, B. Seligmann, P. Strop, K. S. Lam, S. E. Salmon, Innovation and Perspectives in Solid Phase Synthesis and Related Technologies, Collected Papers, Third International Symposium, Oxford, England, (Ed.: R. Epton) 1993, p. 233.
135. M. Lebl, V. Krchftak, P. Safar, A. Stierandova, N. F. Sepetov, P. Kocis, K. S. Lam, Techniques in Protein Chemistry V, 1994, 541-548.
136. V. Nikolaiev, A. Stierandova, V. Krchnak, B. Seligmann, K. S. Lam, S. E. Salmon, S.E.M. Lebl, Lebl, Pept. Res. 1993, 6, 161-170.
137. M. Lebl, M. Patek, P. Kocis, V. Krchfiak, V. Hruby, S. E. Salmon, K. S. Lam, Int. J. Pept. Protein Res. 1993, 41, 201 -203.
138. P. Kocis, V. Krchfiak, M. Lebl, Tetrahedron Lett. 1993, 34, 7251-7252.
139. S. E. Salmon, K. S. Lam, M. Lebl, A. Kandola, P. S. Khattri, S. Wade, M. Patek, P. Kocis, V. Krchnak, D. Thorpe, S. Felder, Proc. Natl. Acad. Sci. USA (Chemistry) 1993, 90, 11708-11712.
140. M. Torneiro, W. C. Still, J. Am. Chem. Soc. 1995, 117, 5887-5888.
141. H. Wennemers, W. C. Still, Tetrahedron Lett. 1994, 35, 6413-6416.
142. R. S. Youngquist, G. R. Fuentes, M. P. Lacey, T. Keough, J. Am. Chem. Soc. 1995,117,3900-3906.
143. H. Wenschuh, M. Beyermann, S. Rothemund, L. A. Carpino, M. Bienert, Tetrahedron Lett. 1995, 36, 1247-1250.
144. R. S. Youngquist, G. R. Fuentes, M. P. Lacey, T. Keough, J. Am. Chem. Soc. 1995,117,3900-3906.
145. J. J. Baldwin, J. J. Burbaum, I. Henderson, M. H. J. Ohlmeyer, J. Am. Chem. Soc. 1995, 117, 5589.
146. A. A. Virgilo, J. A. Ellman, J. Am. Chem. Soc. 1994, 116, 11580-11581.
147. H. Fenniri, K. D. Janda, R. A. Lerner, Proc. Natl. Acad. Sci. USA (Chemistry) 1995, 92, 2278-2282.
148. F. W. Forman, I. Sucholeiki, J. Org. Chem. 1995, 60, 523-528.
149. G. C. Look, M. M. Murphy, D. A. Campbell, M. A. Gallop, Tetrahedron Lett. 1995, 36, 2937-3940.
150. T. A. Rano, K. T. Chapman, Tetrahedron Lett. 1995, 36, 3789-3792.
151. V. Krchnak, Z. Flegelova, A. S. Weichsel, M. Lebl, Tetrahedron Lett. 1995, 36, 61936196.
152. B. Yan, G. Kumaravel, H. Anjaria, A. Wu, R. C. Petter, C. F. Jewell Jr., J. R. Wareing, J. Org. Chem. 1995, 60, 5736-5738.
153. J. R. Hauske, P. Dorff, Tetrahedron Lett. 1995, 36, 1589-1592.
154. M. Patek, B. Drake, M. Lebl, Tetrahedron Lett. 1995, 36, 2227-2230.
155. I. Sucholeiki, Tetrahedron Lett. 1994, 35, 7307-7310.
156. M. Patek, B. Drake, M. Lebl, Tetrahedron Lett. 1994, 35, 9169-9172.
157. J. Nielsen, S. Brenner, K. D. Janda, Proceedings of the 14th American Peptide Symposium, (Eds.: P. T. P. Kaumaya, R. S. Hodges) Columbus, Ohio, 1995, pp. 92-93.
158. F. W. Forman, I. Sucholeiki, J. Org. Chem. 1995, 60, 523-528.
159. J. J. Baldwin, J. J. Burbaum, I. Henderson, M. H. J. Ohlmeyer, J. Am. Chem. Soc. 1995, 117, 5588-5589.
160. D. A. Campbell, J. C. Bermak, T. S. Burkoth, D. V. Patel, J. Am. Chem. Soc. 1995,117, 5381-5382.
161. M. M. Murphy, J. R. Schullek, E. M. Gordon, M. A. Gallop, J. Am. Chem. Soc. 1995, 117, 7029-7030.
162. K. C. Nicolaou, X. Xiao, Z. Parandoosh, A. Senyei, M. P. Nova, Angew. Chem. 1995, 107, 2476-2479;
163. Angew. Chem. Int. Ed. Engl. 1995, 34, 2289-2291.
164. J. J. Burbaum, M. H. J. Ohlmeyer, J. C. Reader, I. Henderson, L. W. Dillard, G. Li, T. L. Randle, N. H. Sigal, D. Chelsky, J. J. Baldwin, Proc. Natl. Acad. Sci. USA (Phar-malogy) 1995, 92, 6027-6031.
165. W. Rapp, M. Maier, G. Schlotterbeck, M. Pursch, K. Albert, E. Bayer, Peptides, Chemistry and Biology, Proceedings of the 14th American Peptide Symposium, (Eds.: P. T. P. Kaumaya, R. S. Hodges), Columbus, Ohio 1995.