메뉴 건너뛰기




Volumn 4, Issue , 2015, Pages

Metastatic squamous cell non-small-cell lung cancer (NSCLC): Disrupting the drug treatment paradigm with immunotherapies

Author keywords

Antibodies; Avelumab; Bevacizumab; Carboplatin; Carcinoma; Cisplatin; Gemcitabine; Immunotherapy; MEDI4736; Molecular targeted therapy; Monoclonal; MPDL3280A; MSB0010718C; Nivolumab; Non small cell lung cancer; Pembrolizumab; Pemetrexed; Programmed cell death 1 receptor; Ramucirumab; Squamous cell

Indexed keywords

DOCETAXEL; NIVOLUMAB; PEMBROLIZUMAB; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR;

EID: 84958202246     PISSN: 17451981     EISSN: 17404398     Source Type: Journal    
DOI: 10.7573/dic.212289     Document Type: Review
Times cited : (35)

References (25)
  • 1
    • 84856497560 scopus 로고    scopus 로고
    • National Cancer Institute. cited 2015 Sep 12
    • National Cancer Institute. SEER stat fact sheets: lung and bronchus cancer [cited 2015 Sep 12]. Available from: http://seer.cancer.gov/statfacts/html/lungb.html
    • SEER Stat Fact Sheets: Lung and Bronchus Cancer
  • 2
    • 84961947728 scopus 로고    scopus 로고
    • GLOBOCAN 2012: Estimated cancer incidence, mortality, and prevalence worldwide in 2012
    • World Health Organization. cited 2015 Sep 12
    • World Health Organization. International Agency for Research on Cancer. GLOBOCAN 2012: estimated cancer incidence, mortality, and prevalence worldwide in 2012. Lung Cancer [cited 2015 Sep 12]. Available from: http://globocan.iarc.fr/Pages/fact-sheets-cancer.aspx
    • Lung Cancer
  • 3
    • 79952597194 scopus 로고    scopus 로고
    • American Cancer Society. cited 2015 Sep 12
    • American Cancer Society. Lung Cancer (Non-Small Cell) [cited 2015 Sep 12]. Available from: http://www.cancer.org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-what-is-non-smallcell-lung-cancer
    • Lung Cancer (Non-Small Cell)
  • 4
    • 84857087591 scopus 로고    scopus 로고
    • Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: Lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations
    • Rekhtman N, Paik PK, Arcila ME, et al. Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations. Clin Cancer Res. 2012;18(4):1167-76. http://dx.doi.org/10.1158/1078-0432.CCR-11-2109
    • (2012) Clin Cancer Res , vol.18 , Issue.4 , pp. 1167-1176
    • Rekhtman, N.1    Paik, P.K.2    Arcila, M.E.3
  • 5
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nature Rev Cancer. 2012;12:252-64. http://dx.doi.org/10.1038/nrc3239
    • (2012) Nature Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 6
    • 84920956732 scopus 로고    scopus 로고
    • PD-1 blockade induces responses by inhibiting adaptive immune resistance
    • Tumeh PH, Harview CL, Yearley JH, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature. 2014;515(7528):568-71. http://dx.doi.org/10.1038/nature13954
    • (2014) Nature , vol.515 , Issue.7528 , pp. 568-571
    • Tumeh, P.H.1    Harview, C.L.2    Yearley, J.H.3
  • 7
    • 84936791837 scopus 로고    scopus 로고
    • Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
    • Brahmer J, Reckamp KL, Baas P, et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med. 2015;373:123-35. http://dx.doi.org/10.1056/NEJMoa1504627
    • (2015) N Engl J Med , vol.373 , pp. 123-135
    • Brahmer, J.1    Reckamp, K.L.2    Baas, P.3
  • 8
    • 84924901863 scopus 로고    scopus 로고
    • Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): A phase 2, single-arm trial
    • Rizvi NA, Mazieres J, Planchard D, et al. Activity and safety of nivolumab, an anti-PD-1 immune checkpoint inhibitor, for patients with advanced, refractory squamous non-small-cell lung cancer (CheckMate 063): a phase 2, single-arm trial. Lancet Oncol. 2015;16:257-65. http://dx.doi.org/10.1016/S1470-2045(15)70054-9
    • (2015) Lancet Oncol , vol.16 , pp. 257-265
    • Rizvi, N.A.1    Mazieres, J.2    Planchard, D.3
  • 9
    • 84929481480 scopus 로고    scopus 로고
    • Pembrolizumab for the treatment of non-small-cell lung cancer
    • Garon EB, Rizvi NA, Hui R, et al. Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med. 2015;372:2018-28. http://dx.doi.org/10.1056/NEJMoa1501824
    • (2015) N Engl J Med , vol.372 , pp. 2018-2028
    • Garon, E.B.1    Rizvi, N.A.2    Hui, R.3
  • 10
    • 84943340055 scopus 로고    scopus 로고
    • PD-1 and PD-L1 expression in NSCLC indicate a favorable prognosis in defined subgroups
    • Henning Schmidt L, Kummel A, Gorlich D, et al. PD-1 and PD-L1 expression in NSCLC indicate a favorable prognosis in defined subgroups. PLoS One. 2015;10(8):e0136023. http://dx.doi.org/10.1371/journal.pone.0136023
    • (2015) PLoS One , vol.10 , Issue.8
    • Henning Schmidt, L.1    Kummel, A.2    Gorlich, D.3
  • 11
    • 84939227614 scopus 로고    scopus 로고
    • Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PD-L1): Sensitivity analysis of trials in melanoma, lung, and genitourinary cancers
    • Carbognin L, Pilotto S, Milella M, et al. Differential activity of nivolumab, pembrolizumab and MPDL3280A according to the tumor expression of programmed death-ligand-1 (PD-L1): sensitivity analysis of trials in melanoma, lung, and genitourinary cancers. PLoS One. 2015;10(6):e0130142. http://dx.doi.org/10.1371/journal.pone.0130142
    • (2015) PLoS One , vol.10 , Issue.6
    • Carbognin, L.1    Pilotto, S.2    Milella, M.3
  • 12
    • 85164882895 scopus 로고    scopus 로고
    • cited 2015 Sep 13
    • Food and Drug Administration. Drugs@FDA: Platinol. Label and approval history [cited 2015 Sep 13]. Available from: http://www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm?fuseaction=Search.Label-ApprovalHistory#apphist
    • Drugs@FDA: Platinol. Label and Approval History
  • 13
    • 85077765203 scopus 로고    scopus 로고
    • Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small cell lung cancer
    • de Castria TB, da Silva EM, Gois AF, Riera R. Cisplatin versus carboplatin in combination with third-generation drugs for advanced non-small cell lung cancer. Cochrane Database Syst Rev. 2013;8:CD009256. http://dx.doi.org/10.1002/14651858.CD009256.pub2
    • (2013) Cochrane Database Syst Rev , vol.8
    • De Castria, T.B.1    Da Silva, E.M.2    Gois, A.F.3    Riera, R.4
  • 14
    • 0042413836 scopus 로고    scopus 로고
    • Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small cell lung cancer: The TAX 326 study group
    • Fossella F, Pereira JF, von Pawel J, et al. Randomized, multinational, phase III study of docetaxel plus platinum combinations versus vinorelbine plus cisplatin for advanced non-small cell lung cancer: the TAX 326 study group. J Clin Oncol. 2003;21(16):3016-24. http://dx.doi.org/10.1200/JCO.2003.12.046
    • (2003) J Clin Oncol , vol.21 , Issue.16 , pp. 3016-3024
    • Fossella, F.1    Pereira, J.F.2    Von Pawel, J.3
  • 15
    • 25444511051 scopus 로고    scopus 로고
    • Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer
    • Belani CP, Lee JS, Socinski MA, et al. Randomized phase III trial comparing cisplatin-etoposide to carboplatin-paclitaxel in advanced or metastatic non-small cell lung cancer. Ann Oncol. 2005;16:1069-75. http://dx.doi.org/10.1093/annonc/mdi216
    • (2005) Ann Oncol , vol.16 , pp. 1069-1075
    • Belani, C.P.1    Lee, J.S.2    Socinski, M.A.3
  • 16
    • 49049089802 scopus 로고    scopus 로고
    • Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naïve patients with advanced-stage non-small-cell lung cancer
    • Scagliotti GV, Parikh P, von Pawel J, et al. Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naïve patients with advanced-stage non-small-cell lung cancer. J Clin Oncol. 2008;26(21):3543-51.
    • (2008) J Clin Oncol , vol.26 , Issue.21 , pp. 3543-3551
    • Scagliotti, G.V.1    Parikh, P.2    Von Pawel, J.3
  • 17
    • 84906903314 scopus 로고    scopus 로고
    • Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): A multicenter, double-blind, randomised phase 3 trial
    • Garon EB, Ciuleanu TE, Arrieta O, et al. Ramucirumab plus docetaxel versus placebo plus docetaxel for second-line treatment of stage IV non-small-cell lung cancer after disease progression on platinum-based therapy (REVEL): a multicenter, double-blind, randomised phase 3 trial. Lancet. 2014;384:665-73. http://dx.doi.org/10.1016/S0140-6736(14)60845-X
    • (2014) Lancet , vol.384 , pp. 665-673
    • Garon, E.B.1    Ciuleanu, T.E.2    Arrieta, O.3
  • 19
    • 84920655625 scopus 로고    scopus 로고
    • PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients
    • D'Incecco A, Andreozzi M, Ludovini V, et al. PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients. Br J Cancer. 2015;112:95-102.
    • (2015) Br J Cancer , vol.112 , pp. 95-102
    • D'Incecco, A.1    Andreozzi, M.2    Ludovini, V.3
  • 20
    • 85164888664 scopus 로고    scopus 로고
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02041533 [cited 2015 Sep 15]
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02041533 [cited 2015 Sep 15]. Available from: https://clinicaltrials.gov/show/NCT02041533
  • 21
    • 85164888573 scopus 로고    scopus 로고
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02220894 [cited 2015 Sep 15]
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02220894 [cited 2015 Sep 15]. Available from: https://clinicaltrials.gov/ct2/show/NCT02220894?term=pembrolizumab+and+lung&rank=9
  • 22
    • 85164892518 scopus 로고    scopus 로고
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02142738 [cited 2015 Sep 15]
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02142738 [cited 2015 Sep 15]. Available from: https://clinicaltrials.gov/ct2/show/NCT02142738?term=pembrolizumab+and+lung&rank=10
  • 23
    • 85164884375 scopus 로고    scopus 로고
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02477826 [cited 2015 Sep 15]
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number: NCT02477826 [cited 2015 Sep 15]. Available from: https://www.clinicaltrials.gov/ct2/show/NCT02477826?term=nivolumab+and+lung&rank=4
  • 24
    • 85164898607 scopus 로고    scopus 로고
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number NCT02039674 [cited 2015 Sep 15]
    • National Institutes of Health. Clinicaltrials.gov. NCI clinical trial number NCT02039674 [cited 2015 Sep 15]. Available from: https://clinicaltrials.gov/ct2/show/NCT02039674?term=pembrolizumab+and+lung&rank=13
  • 25
    • 85164886142 scopus 로고    scopus 로고
    • National Institutes of Health. Clinicaltrials.gov [cited 2015 Sep 15]
    • National Institutes of Health. Clinicaltrials.gov [cited 2015 Sep 15]. Available from: https://clinicaltrials.gov/ct2/results?term=PD-L1+and+lung&Search=Search


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.