An Exploration of the Role of MicroRNAs in Psoriasis

Medicine (United States)

Volumn 94, Issue 45, 2015, Pages e2030-

  Huang, Run Yue ^a   Li, Li ^a   Wang, Mao Jie ^a   Chen, Xiu Min ^a   Huang, Qing Chun ^a   Lu, Chuan Jian ^a  

^a GUANGZHOU UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; MICRORNA;

ARTICLE; ATOPIC DERMATITIS; BODY SURFACE; DISEASE MARKER; DOWN REGULATION; GENE FUNCTION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; IMMUNE DYSREGULATION; INFLAMMATION; INFLAMMATORY INFILTRATE; KERATINOCYTE; PHENOTYPE; PRIORITY JOURNAL; PSORIASIS; PSORIASIS AREA AND SEVERITY INDEX; PSORIASIS VULGARIS; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SKIN DEFECT; SYSTEMATIC REVIEW; BLOOD EXAMINATION; GENE EXPRESSION PROFILING; GENETICS; HAIR; IMMUNOLOGY; IMMUNOPATHOLOGY; META ANALYSIS; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SKIN;

BIOMARKERS; DOWN-REGULATION; GENE EXPRESSION PROFILING; HAIR; HEMATOLOGIC TESTS; HUMANS; IMMUNE SYSTEM DISEASES; INFLAMMATION; KERATINOCYTES; MICRORNAS; POLYMORPHISM, GENETIC; PSORIASIS; SIGNAL TRANSDUCTION; SKIN;

EID: 84958150943     PISSN: 00257974     EISSN: 15365964     Source Type: Journal    
DOI: 10.1097/MD.0000000000002030     Document Type: Article

References (58)

1. Zhao YK, Zhang YQ, Wang F, et al. Developing Shingles-Induced Koebner Phenomenon in a Patient With Psoriasis: A Case Report. Medicine. 2015;94:e1009.
2. Sonkoly E, Wei T, Janson PC, et al. MicroRNAs: novel regulators involved in the pathogenesis of psoriasis? PLoS One. 2007;2:e610.
3. Boehncke WH, Schön MP. Psoriasis. Lancet. 2015;386:983-994.
4. Chandra A, Ray A, Senapati S, et al. Genetic and epigenetic basis of psoriasis pathogenesis. Mol Immunol. 2015;64:313-323.
5. Trowbridge RM, Pittelkow MR. Epigenetics in the pathogenesis and pathophysiology of psoriasis vulgaris. J Drugs Dermatol. 2014;13:111-118.
6. Jinnin M. [microRNA in autoimmune disorders]. Nihon Rinsho Meneki Gakkai Kaishi. 2011;34:439-446.
7. Deng X, Su Y, Wu H, et al. The role of microRNAs in autoimmune diseases with skin involvement. Scand J Immunol. 2015;81:153-165.
8. Ivey KN, Srivastava D. microRNAs as developmental regulators. Cold Spring Harb Perspect Biol. 2015;7:a008144.
9. Singh RP, Massachi I, Manickavel S, et al. The role of miRNA in inflammation and autoimmunity. Autoimmun Rev. 2013;12:1160-1165.
10. Jimenez SA, Piera-Velazquez S. Potential role of human-specific genes, human-specific microRNAs and human-specific non-coding regulatory RNAs in the pathogenesis of systemic sclerosis and Sjogren's syndrome. Autoimmun Rev. 2013;12:1046-1051.
11. Grinberg-Bleyer Y, Dainichi T, Oh H, et al. Cutting edge: NFkappaB p65 and c-Rel control epidermal development and immune homeostasis in the skin. J Immunol. 2015;194:2472-2476.
12. Pivarcsi A, Stahle M, Sonkoly E. Genetic polymorphisms altering microRNA activity in psoriasis-A key to solve the puzzle of missing heritability? Exp Dermatol. 2014;23:620-624.
13. Xu N, Meisgen F, Butler LM, et al. MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40. J Immunol. 2013;190:678-688.
14. Joyce CE, Zhou X, Xia J, et al. Deep sequencing of small RNAs from human skin reveals major alterations in the psoriasis miRNAome. Hum Mol Genet. 2011;20:4025-4040.
15. Lovendorf MB, Mitsui H, Zibert JR, et al. Laser capture microdissection followed by next-generation sequencing identifies diseaserelated microRNAs in psoriatic skin that reflect systemic microRNA changes in psoriasis. Exp Dermatol. 2015;24:187-193.
16. Ichihara A, Jinnin M, Oyama R, et al. Increased serum levels of miR-1266 in patients with psoriasis vulgaris. Eur J Dermatol. 2012;22:68-71.
17. Meisgen F, Xu N, Wei T, et al. MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis. Exp Dermatol. 2012;21:312-314.
18. Guinea-Viniegra J, Jimenez M, Schonthaler HB, et al. Targeting miR-21 to treat psoriasis. Sci Transl Med. 2014;6:225re221.
19. Roberts JC, Warren RB, Griffiths CE, et al. Expression of microRNA-184 in keratinocytes represses argonaute 2. Hum Mol Genet. 2013;228:2314-2323.
20. Primo MN, Bak RO, Schibler B, et al. Regulation of proinflammatory cytokines TNFalpha and IL24 by microRNA-203 in primary keratinocytes. Cytokine. 2012;60:741-748.
21. Bracke S, Desmet E, Guerrero-Aspizua S, et al. Identifying targets for topical RNAi therapeutics in psoriasis: assessment of a new in vitro psoriasis model. Arch Dermatol Res. 2013;305:501-512.
22. Nissan X, Denis JA, Saidani M, et al. miR-203 modulates epithelial differentiation of human embryonic stem cells towards epidermal stratification. Dev Biol. 2011;356:506-515.
23. Xu N, Brodin P, Wei T, et al. MiR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2. J Invest Dermatol. 2011;131:1521-1529.
24. Lerman G, Avivi C, Mardoukh C, et al. MiRNA expression in psoriatic skin: reciprocal regulation of hsa-miR-99a and IGF-1R. PLoS One. 2011;6:e20916.
25. Xia P, Fang X, Zhang ZH, et al. Dysregulation of miRNA146a versus IRAK1 induces IL-17 persistence in the psoriatic skin lesions. Immunol Lett. 2012;148:151-162.
26. Lovendorf MB, Zibert JR, Gyldenlove M, et al. MicroRNA-223 and miR-143 are important systemic biomarkers for disease activity in psoriasis. J Dermatol Sci. 2014;75:133-139.
27. Garcia-Rodriguez S, Arias-Santiago S, Orgaz-Molina J, et al. abnormal levels of expression of plasma microRNA-33 in patients with psoriasis. Actas Dermosifiliogr. 2014;105:497-503.
28. Zhao M, Wang LT, Liang GP, et al. Up-regulation of microRNA-210 induces immune dysfunction via targeting FOXP3 in CD4(\+) T cells of psoriasis vulgaris. Clin Immunol. 2014;150: 22-30.
29. Hirao H, Jinnin M, Ichihara A, et al. Detection of hair root miR-19a as a novel diagnostic marker for psoriasis. Eur J Dermatol. 2013;23:807-811.
30. Tsuru Y, Jinnin M, Ichihara A, et al. miR-424 levels in hair shaft are increased in psoriatic patients. J Dermatol. 2014;41:382-385.
31. Xia J, Joyce CE, Bowcock AM, et al. Noncanonical microRNAs and endogenous siRNAs in normal and psoriatic human skin. Hum Mol Genet. 2013;22:737-748.
32. Sethupathy P, Collins FS. MicroRNA target site polymorphisms and human disease. Trends Genet. 2008;24:489-497.
33. Wu X, Dong H, Luo L, et al. A novel statistic for genome-wide interaction analysis. PLoS Genet. 2010;6:e1001131.
34. Zhang W, Yi X, Guo S, et al. A single-nucleotide polymorphism of miR-146a and psoriasis: an association and functional study. J Cell Mol Med. 2014;18:2225-2234.
35. Chatzikyriakidou A, Voulgari PV, Georgiou I, et al. The role of microRNA-146a (miR-146a) and its target IL-1R-associated kinase (IRAK1) in psoriatic arthritis susceptibility. Scand J Immunol. 2010;71:382-385.
36. Wu LS, Li FF, Sun LD, et al. A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in central south Chinese population. Hum Genet. 2011;130:749-757.
37. Majorczyk E, Matusiak L, Nowak I, et al. A single nucleotide polymorphism-35 kb T C (rs9264942) is strongly associated with psoriasis vulgaris depending on HLA-Cw(-)06. Hum Immunol. 2014;75:504-507.
38. Schonthaler HB, Guinea-Viniegra J, Wagner EF. Targeting inflammation by modulating the Jun/AP-1 pathway. Ann Rheum Dis. 2011;70(Suppl 1): i109-112.
39. Kitoh A, Nomura T, Kabashima K. TGFbeta1, an epidermal controller of skin dendritic cell homeostasis. J Invest Dermatol. 2013;133:9-11.
40. Xu WD, Pan HF, Li JH, et al. MicroRNA-21 with therapeutic potential in autoimmune diseases. Expert Opin Ther Targets. 2013;17:659-665.
41. Fu D, Yu W, Li M, et al. MicroRNA-138 regulates the balance of Th1/Th2 via targeting RUNX3 in psoriasis. Immunol Lett. 2015;166:55-62.
42. Fayyad-Kazan H, Rouas R, Fayyad-Kazan M, et al. MicroRNA profile of circulating CD4-positive regulatory T cells in human adults and impact of differentially expressed microRNAs on expression of two genes essential to their function. J Biol Chem. 2012;287:9910-9922.
43. Choi HR, Nam KM, Park SJ, et al. Suppression of miR135b increases the proliferative potential of normal human keratinocytes. J Invest Dermatol. 2014;134:1161-1164.
44. Guo S, Zhang W, Wei C, et al. Serum and skin levels of miR-369-3p in patients with psoriasis and their correlation with disease severity. Eur J Dermatol. 2013;23:608-613.
45. Xia J, Zhang W. MicroRNAs in normal and psoriatic skin. Physiol Genomics. 2014;46:113-122.
46. Zibert JR, Lovendorf MB, Litman T, et al. MicroRNAs and potential target interactions in psoriasis. J Dermatol Sci. 2010;58: 177-185.
47. Gu X, Nylander E, Coates PJ, et al. Effect of narrow-band ultraviolet B phototherapy on p63 and microRNA (miR-21 and miR-125b) expression in psoriatic epidermis. Acta Derm Venereol. 2011;91: 392-397.
48. Finch PW, Murphy F, Cardinale I, et al. Altered expression of keratinocyte growth factor and its receptor in psoriasis. Am J Pathol. 1997;151:1619-1628.
49. Ichihara A, Jinnin M, Yamane K, et al. microRNA-mediated keratinocyte hyperproliferation in psoriasis vulgaris. Br J Dermatol. 2011;165:1003-1010.
50. Yan S, Xu Z, Lou F, et al. NF-kappaB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nat Commun. 2015;6:7652.
51. Liang Y, Pan HF, Ye DQ. microRNAs function in CD8\+T cell biology. J Leukoc Biol. 2015;97:487-497.
52. Pivarcsi A, Meisgen F, Xu N, et al. Changes in the level of serum microRNAs in patients with psoriasis after antitumour necrosis factor-alpha therapy. Br J Dermatol. 2013;169:563-570.
53. Wang L, Zhang H, Rodriguez S, et al. Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-kappaB-dependent manner. Cell stem cell. 2014;15:51-65.
54. Baldoni S, Sportoletti P, Del Papa B, et al. NOTCH and NF-kappaB interplay in chronic lymphocytic leukemia is independent of genetic lesion. Int J Hematol. 2013;98:153-157.
55. Peng H, Kaplan N, Hamanaka RB, et al. microRNA-31/factorinhibiting hypoxia-inducible factor 1 nexus regulates keratinocyte differentiation. Proc Natl Acad Sci USA. 2012;109:14030-14034.
56. Chowdhari S, Saini N. hsa-miR-4516 mediated downregulation of STAT3/CDK6/UBE2N plays a role in PUVA induced apoptosis in keratinocytes. J Cell Physiol. 2014;229:1630-1638.
57. Killeen ME, Ferris L, Kupetsky EA, et al. Signaling through purinergic receptors for ATP induces human cutaneous innate and adaptive Th17 responses: implications in the pathogenesis of psoriasis. J Immunol. 2013;190:4324-4336.
58. Lovendorf MB, Zibert JR, Hagedorn PH, et al. Comparison of microRNA expression using different preservation methods of matched psoriatic skin samples. Exp Dermatol. 2012;21:299-301.